Search Results - "DEL POETA, M"

The immunosuppressant FK506 and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein by Odom, A, Del Poeta, M, Perfect, J, Heitman, J

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Functional characterization of the Aspergillus nidulans glucosylceramide pathway reveals that LCB Δ8‐desaturation and C9‐methylation are relevant to filamentous growth, lipid raft localization and Psd1 defensin activity by Fernandes, C. M., de Castro, P. A., Singh, A., Fonseca, F. L., Pereira, M. D., Vila, T. V. M., Atella, G. C., Rozental, S., Savoldi, M., Del Poeta, M., Goldman, G. H., Kurtenbach, E.

“…Summary C8‐desaturated and C9‐methylated glucosylceramide (GlcCer) is a fungal‐specific sphingolipid that plays an important role in the growth and virulence…”
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Toward Developing a Universal Treatment for Fungal Disease Using Radioimmunotherapy Targeting Common Fungal Antigens by Bryan, R. A., Guimaraes, A. J., Hopcraft, S., Jiang, Z., Bonilla, K., Morgenstern, A., Bruchertseifer, F., Del Poeta, M., Torosantucci, A., Cassone, A., Nosanchuk, J. D., Casadevall, A., Dadachova, E.

“…Background Previously, we demonstrated the ability of radiolabeled antibodies recognizing the cryptococcal polysaccharide capsule to kill Cryptococcus…”
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Rapamycin and Less Immunosuppressive Analogs Are Toxic to Candida albicans and Cryptococcus neoformans via FKBP12-Dependent Inhibition of TOR by CRUZ, M. Cristina, GOLDSTEIN, Alan L, BLANKENSHIP, Jill, DEL POETA, Maurizio, PERFECT, John R, MCCUSKER, John H, BENNANI, Youssef L, CARDENAS, Maria E, HEITMAN, Joseph

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In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds by DEL POETA, M, SCHELL, W. A, PERFECT, J. R

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Comparison of broth dilution and semisolid agar dilution for in vitro susceptibility testing of Cryptococcus neoformans by Del Poeta, M, Barchiesi, F, Morbiducci, V, Arzeni, D, Marinucci, G, Ancarani, F, Scalise, G

“…We compared the in vitro activity of amphotericin B, flucytosine, itraconazole, fluconazole, ketoconazole and miconazole against 18 strains of Cryptococcus…”
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In-vitro activity of dicationic aromatic compounds and fluconazole against Cryptococcus neoformans and Candida spp by DEL POETA, M, BIXEL, A. S, BARCHIESI, F, TIDWELL, R. R, BOYKIN, D, SCALISE, G, PERFECT, J. R

“…We investigated the in-vitro activity of three selected dicationic aromatic compounds for nine clinical isolates of Cryptococcus neoformans and 93 clinical…”
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Role of phagocytosis in the virulence of Cryptococcus neoformans by Del Poeta, Maurizio

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Role of Sphingolipids in Microbial Pathogenesis by Heung, Lena J, Luberto, Chiara, Del Poeta, Maurizio

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Transmission of Fluconazole-Resistant Candida albicans Between Patients with AIDS and Oropharyngeal Candidiasis Documented by Pulsed-Field Gel Electrophoresis by Barchiesi, Francesco, Hollis, Richard J., Del Poeta, Maurizio, McGough, Deanna A., Scalise, Giorgio, Rinaldi, Michael G., Pfaller, Michael A.

“…Electrophoretic karyotype and restriction endonuclease analysis of genomic DNA were used for the typing of nine isolates of Candida albicans from the oral…”
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Ergosterol Biosynthesis Inhibitors Become Fungicidal when Combined with Calcineurin Inhibitors against Candida albicans, Candida glabrata, and Candida krusei by ONYEWU, Chiatogu, BLANKENSHIP, Jill R, DEL POETA, Maurizio, HEITMAN, Joseph

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Functional characterization of the Aspergillus nidulans glucosylceramide pathway reveals that LCB [Delta]8-desaturation and C9-methylation are relevant to filamentous growth, lipid raft localization and Psd1 defensin activity by Fernandes, C M, de Castro, P A, Singh, A, Fonseca, F L, Pereira, M D, Vila, T V M, Atella, G C, Rozental, S, Savoldi, M, Del Poeta, M, Goldman, G H, Kurtenbach, E

“…Summary C8-desaturated and C9-methylated glucosylceramide (GlcCer) is a fungal-specific sphingolipid that plays an important role in the growth and virulence…”
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Functional characterization of the A spergillus nidulans glucosylceramide pathway reveals that LCB Δ8‐desaturation and C9‐methylation are relevant to filamentous growth, lipid raft localization and Ps d1 defensin activity by Fernandes, C. M., de Castro, P. A., Singh, A., Fonseca, F. L., Pereira, M. D., Vila, T. V. M., Atella, G. C., Rozental, S., Savoldi, M., Del Poeta, M., Goldman, G. H., Kurtenbach, E.

“…Summary C8‐desaturated and C9‐methylated glucosylceramide (GlcCer) is a fungal‐specific sphingolipid that plays an important role in the growth and virulence…”
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Functional characterization of the Aspergillus nidulans glucosylceramide pathway reveals that LCB Delta 8-desaturation and C9-methylation are relevant to filamentous growth, lipid raft localization and Psd1 defensin activity by Fernandes, C M, de Castro, PA, Singh, A, Fonseca, F L, Pereira, MD, Vila, TVM, Atella, G C, Rozental, S, Savoldi, M, Del Poeta, M, Goldman, G H, Kurtenbach, E

“…C8-desaturated and C9-methylated glucosylceramide (GlcCer) is a fungal-specific sphingolipid that plays an important role in the growth and virulence of many…”
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Lipid Signaling in Pathogenic Fungi by RHOME, Ryan, DEL POETA, Maurizio

“…Lipid signaling in pathogenic fungi has been studied to determine the role of these pathways in fungal biology and human infections. Owing to their unique…”
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Calcineurin is essential for survival during membrane stress in Candida albicans by Cruz, M.Cristina, Goldstein, Alan L., Blankenship, Jill R., Del Poeta, Maurizio, Davis, Dana, Cardenas, Maria E., Perfect, John R., McCusker, John H., Heitman, Joseph

“…The immunosuppressants cyclosporin A (CsA) and FK506 inhibit the protein phosphatase calcineurin and block T‐cell activation and transplant rejection…”
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Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans by Luberto, Chiara, Martinez-Mariño, Beatriz, Taraskiewicz, Daniel, Bolaños, Benjamin, Chitano, Pasquale, Toffaletti, Dena L., Cox, Gary M., Perfect, John R., Hannun, Yusuf A., Balish, Edward, Poeta, Maurizio Del

“…Cryptococcus neoformans is a fungal pathogen that, after inhalation, can disseminate to the brain. Host alveolar macrophages (AMs) represent the first defense…”
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Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans by Del Poeta, M, Cruz, M C, Cardenas, M E, Perfect, J R, Heitman, J

“…Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening infections of the central nervous system. Existing therapies include…”
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The Role and Mechanism of Diacylglycerol-Protein Kinase C1 Signaling in Melanogenesis by Cryptococcus neoformans by Heung, Lena J, Kaiser, Ashley E, Luberto, Chiara, Del Poeta, Maurizio

“…The fungus Cryptococcus neoformans is an opportunistic human pathogen that causes a life-threatening meningoencephalitis by expression of virulence factors…”
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Turbidimetric and visual criteria for in vitro susceptibility testing of Cryptococcus neoformans clinical isolates by Del Poeta, M, Barchiesi, F, Arzeni, D, Marinucci, G, Scalise, G

“…The drug concentration which inhibited 50% of growth (IC50), the lowest drug concentration at which growth was less than 30% of that in a positive control well…”
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