Search Results - "DEL BUFALO, D"

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ by Noto, A, De Vitis, C, Pisanu, M E, Roscilli, G, Ricci, G, Catizone, A, Sorrentino, G, Chianese, G, Taglialatela-Scafati, O, Trisciuoglio, D, Del Bufalo, D, Di Martile, M, Di Napoli, A, Ruco, L, Costantini, S, Jakopin, Z, Budillon, A, Melino, G, Del Sal, G, Ciliberto, G, Mancini, R

“…Recent evidences suggest that stearoyl-CoA-desaturase 1 (SCD1), the enzyme involved in monounsaturated fatty acids synthesis, has a role in several cancers. We…”
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N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore–microtubule dynamics by Orticello, M, Fiore, M, Totta, P, Desideri, M, Barisic, M, Passeri, D, Lenzi, J, Rosa, A, Orlandi, A, Maiato, H, Bufalo, D Del, Degrassi, F

“…Mitotic proteins are attractive targets to develop molecular cancer therapeutics due to the intimate interdependence between cell proliferation and mitosis. In…”
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Involvement of RB gene family in tumor angiogenesis by Gabellini, C, Del Bufalo, D, Zupi, G

“…Angiogenesis, the development of new blood vessels from pre-existing vessels, represents a fundamental step in tumor progression and metastatization. The…”
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Involvement of hTERT in apoptosis induced by interference with Bcl-2 expression and function by Del Bufalo, D, Rizzo, A, Trisciuoglio, D, Cardinali, G, Torrisi, M R, Zangemeister-Wittke, U, Zupi, G, Biroccio, A

“…Here, we investigated the role of telomerase on Bcl-2-dependent apoptosis. To this end, the 4625 Bcl-2/Bcl-xL bispecific antisense oligonucleotide and the…”
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relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells by RICCA, A, BIROCCIO, A, TRISCIUOGLIO, D, CIPPITELLI, M, ZUPI, G, DEL BUFALO, D

“…We previously demonstrated that bcl-2 over-expression increases the malignant behaviour of the MCF7 ADR human breast cancer cell line and enhances nuclear…”
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Small molecules targeted to the microtubule–Hec1 interaction inhibit cancer cell growth through microtubule stabilization by Ferrara, M, Sessa, G, Fiore, M, Bernard, F, Asteriti, I A, Cundari, E, Colotti, G, Ferla, S, Desideri, M, Buglioni, S, Trisciuoglio, D, Del Bufalo, D, Brancale, A, Degrassi, F

“…Highly expressed in cancer protein 1 (Hec1) is a subunit of the kinetochore (KT)-associated Ndc80 complex, which ensures proper segregation of sister…”
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Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells by Trisciuoglio, D, Gabellini, C, Desideri, M, Ragazzoni, Y, De Luca, T, Ziparo, E, Del Bufalo, D

“…In addition to act as an antiapoptotic protein, B-cell lymphoma (bcl)-2 can also promote tumor angiogenesis. In this context, we have previously demonstrated…”
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Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ by Noto, A, De Vitis, C, Pisanu, M E, Roscilli, G, Ricci, G, Catizone, A, Sorrentino, G, Chianese, G, Taglialatela-Scafati, O, Trisciuoglio, D, Del Bufalo, D, Di Martile, M, Di Napoli, A, Ruco, L, Costantini, S, Jakopin, Z, Budillon, A, Melino, G, Del Sal, G, Ciliberto, G, Mancini, R

“…This corrects the article DOI: 10.1038/onc.2017.75…”
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Aurora B kinase inhibitor AZD1152: determinants of action and ability to enhance chemotherapeutics effectiveness in pancreatic and colon cancer by Azzariti, A, Bocci, G, Porcelli, L, Fioravanti, A, Sini, P, Simone, G M, Quatrale, A E, Chiarappa, P, Mangia, A, Sebastian, S, Del Bufalo, D, Del Tacca, M, Paradiso, A

“…Background: AZD1152, the prodrug for AZD1152-hydroxyquinazoline pyrazol anilide (HQPA), is a selective inhibitor of Aurora B kinase activity. Preclinical…”
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Erratum: Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ by Noto, A, De Vitis, C, Pisanu, M E, Roscilli, G, Ricci, G, Catizone, A, Sorrentino, G, Chianese, G, Taglialatela-Scafati, O, Trisciuoglio, D, Del Bufalo, D, Di Martile, M, Di Napoli, A, Ruco, L, Costantini, S, Jakopin, Z, Budillon, A, Melino, G, Del Sal, G, Ciliberto, G, Mancini, R

“…Correction to: Oncogene (2017) 36, 4573–4584; doi: 10.1038/onc.2017.75; published online 3 April 2017 Since the publication of the above article, the authors…”
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Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells by Di Martile, M, Desideri, M, De Luca, T, Buglioni, S, Del Bufalo, D, Trisciuoglio, D

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Role of bcl-2 in cancer–stroma interplay by Farini, V, Trisciuoglio, D, Desideri, M, Di Martile, M, Tupone, M.G, D’Aguanno, S, Del Bufalo, D

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241: Bcl-xL protein overexpression enhances tumor progression of human melanoma cells in zebrafish xenograft model: involvement of interleukin 8 by Gabellini, C, Gómez-Abenza, E, De Oliveira, S, Del Bufalo, D, Mulero, V

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Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein by D’Aguanno, S, Trisciuoglio, D, Desideri, M, Farini, V, Di Martile, M, De Luca, T, Tupone, M.G, Urbani, A, Del Bufalo, D

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Enhancement of doxorubicin cytotoxicity by histone deacetylase inhibition in human sarcoma cells by Tupone, M.G, Trisciuoglio, D, Desideri, M, Di Martile, M, Buglioni, S, Loria, R, Ferraresi, V, Baldini, N, Biagini, R, Del Bufalo, D

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Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein by Trisciuoglio, D, Desideri, M, Farini, V, De Luca, T, Di Martile, M, Tupone, M G, Urbani, A, D'Aguanno, S, Del Bufalo, D

“…Members of the bcl-2 protein family share regions of sequence similarity, the bcl-2 homology (BH) domains. Bcl-2, the most studied member of this family, has…”
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284: Evidence of a correlation between bcl-2 protein and miR-211 expression in melanoma cell lines by De Luca, T, Pelosi, A, Trisciuoglio, D, D’Aguanno, S, Felsani, A, Urbani, A, Rizzo, M.G, Del Bufalo, D

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822: The histone acetyltransferases inhibitor CPTH6 preferentially inhibits proliferation of patient-derived lung cancer stem cells in vitro and in vivo by Di Martile, M, Desideri, M, Gabellini, C, Eramo, A, Carradori, S, Secci, D, Milella, M, Del Bufalo, D, Trisciuoglio, D

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The thiazole derivative CPTH6 impairs autophagy by Ragazzoni, Y, Desideri, M, Gabellini, C, De Luca, T, Carradori, S, Secci, D, Nescatelli, R, Candiloro, A, Condello, M, Meschini, S, Del Bufalo, D, Trisciuoglio, D

“…We have previously demonstrated that the thiazole derivative 3-methylcyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone (CPTH6) induces apoptosis and…”
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Lost in translation: bridging the gap between cancer research and effective therapies by Del Bufalo, D, Bagnato, A, Fusco, A, Milella, M

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