Search Results - "DEGRAY, Gerald"

In vitro microtumors provide a physiologically predictive tool for breast cancer therapeutic screening by Benton, Gabriel, DeGray, Gerald, Kleinman, Hynda K, George, Jay, Arnaoutova, Irina

“…Many anti-cancer drugs fail in human trials despite showing efficacy in preclinical models. It is clear that the in vitro assays involving 2D monoculture do…”
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Evidence for the Involvement of Tyrosine Kinase ZAP 70 in Nuclear Retinoid Receptor-dependent Transactivation in T Lymphocytes by Ishaq, Mohammad, DeGray, Gerald, Natarajan, Ven

“…Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are transcription factors that control diverse cellular functions during development and…”
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SS4-4 Ku70 is a novel cytosolic DNA sensor and induces type-III IFN rather than Type-I IFN by Zhang, Xing, Brann, Terrence W., Lidie, Kristy B., Zhou, Ming, Oguariri, Raphael M., Yang, Jun, Fullmer, Brandie, Zheng, Xin, Degray, Gerald S., Imamichi, Hiromi, Huang, Da-Wei, Lempicki, Richard A., Baseler, Michael W., Veenstra, Timothy D., Young, Howard A., Clifford Lane, H., Imamichi, Tomozumi

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Abstract 324: High throughput triculture: A breast cancer spheroid model for drug screening by Benton, Gabriel J., DeGray, Gerald, Arnaoutova, Irina, Kleinman, Hynda K., George, Jay

“…Abstract Many drugs that show promise in preclinical evaluation fail miserably during clinical trials, and the inability of current preclinical models to…”
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Abstract 2033: A comprehensive 3D triple coculture model for evaluating breast cancer progression by Benton, Gabriel J., George, Jay, DeGray, Gerald, Arnaoutova, Irina, Kleinman, Hynda K.

“…Abstract Current models for evaluating breast cancer progression lack a comprehensive, physiological approach to modeling the complex tumor microenvironment…”
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Lack of Compartmentalization of HIV-1 Quasispecies Between the Gut and Peripheral Blood Compartments by Imamichi, Hiromi, DeGray, Gerald, Dewar, Robin L., Mannon, Peter, Yao, Michael, Chairez, Cheryl, Sereti, Irini, Kovacs, Joseph A.

“…Compartmental differences in human immunodeficiency virus type 1 (HIV-1) between the gut and peripheral blood and within the gut were examined. Biopsy…”
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Expression of an Antimicrobial Peptide via the Chloroplast Genome to Control Phytopathogenic Bacteria and Fungi by Gerald De Gray, Kanniah Rajasekaran, Franzine Smith, John Sanford, Daniell, Henry

“…The antimicrobial peptide MSI-99, an analog of magainin 2, was expressed via the chloroplast genome to obtain high levels of expression in transgenic tobacco…”
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HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy by IMAMICHI, Hiromi, DEGRAY, Gerald, ASMUTH, David M, FISCHL, Margaret A, LANDAY, Alan L, LEDERMAN, Michael M, SERETI, Irini

“…administration of recombinant human interleukin (IL)-7 leads to CD4 and CD8 T-cell expansions in HIV-infected individuals, demonstrating promising capacity for…”
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HIV-1 viruses detected during episodic blips following IL-7 administration are similar to the viruses present before and after IL-7 therapy by Imamichi, Hiromi, DeGray, Gerald, Asmuth, David M., Fischl, Margaret A., Landay, Alan L., Lederman, Michael M., Sereti, Irini

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Zap70 Signaling Pathway Mediates Glucocorticoid Receptor-Dependent Transcriptional Activation: Role in the Regulation of Annexin 1 Expression in T Cells by Ishaq, Mohammad, DeGray, Gerald, Mou, Kathy, Aguilera, Angelica, Yang, Jun, Lempicki, Richard A, Hazen, Allison, Natarajan, Ven

“…We have recently shown that Zap70 is important in retinoid receptor-dependent transactivation in T lymphocytes. We report that Zap70 signaling is also…”
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Protein Kinase Cθ Modulates Nuclear Receptor-Corepressor Interaction during T Cell Activation by Mohammad Ishaq, Gerald DeGray, Ven Natarajan

“…Transcriptional repression by nuclear receptor corepressors plays a critical role in T cell development. However, the role of these corepressors in T cell…”
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Protein Kinase Cθ Modulates Nuclear Receptor-Corepressor Interaction during T Cell Activation by Ishaq, Mohammad, DeGray, Gerald, Natarajan, Ven

“…Transcriptional repression by nuclear receptor corepressors plays a critical role in T cell development. However, the role of these corepressors in T cell…”
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