Search Results - "DEFTOS, L. J"
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Chromogranin A: its role in endocrine function and as an endocrine and neuroendocrine tumor marker
Published in Endocrine reviews (01-05-1991)“…CgA is a 49 kilodalton protein that is present in the secretory granules of most endocrine and many neuroendocrine cells. Detection of CgA in cells by…”
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Treatment of Paget's Disease — Taming the Wild Osteoclast
Published in The New England journal of medicine (01-09-2005)“…Dr. L.J. Deftos writes that in Paget's disease, as in many other skeletal disorders, the osteoclast is the cellular villain; it literally chews up the…”
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Monitoring of skeletal progression of prostate cancer by GFP imaging, X-ray, and serum OPG and PTHrP
Published in The Prostate (15-02-2005)“…Background Prostate cancers (PCas) produce factors that can serve as biomarkers for tumor metastasis and bone progression. Transduced GFP expression by cancer…”
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Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression
Published in Osteoarthritis and cartilage (01-05-2005)“…Growth plate chondrocytes up-regulate calcium-sensing receptor (CaR) expression as they mature to hypertrophy. In cells other than chondrocytes, extracellular…”
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The effect of electroporation on iontophoretic transdermal delivery of calcium regulating hormones
Published in Journal of controlled release (15-05-2000)“…Electrically-assisted delivery by iontophoresis and/or electroporation was used in vitro to deliver the calcium regulating hormones, salmon calcitonin (sCT)…”
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Quantitative computed tomography in the evaluation of spinal osteoporosis following spinal cord injury
Published in Osteoporosis international (01-10-2000)“…Disuse osteoporosis occurs in the lower extremities of patients with spinal cord injury (SCI). However, spinal osteoporosis is not usually observed in these…”
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Parathyroid hormone-related protein induces interleukin 8 production by prostate cancer cells via a novel intracrine mechanism not mediated by its classical nuclear localization sequence
Published in Cancer research (Chicago, Ill.) (01-03-2001)“…PTHrP (parathyroid hormone-related protein) overexpression by prostate carcinoma cells has been implicated in tumor progression. Although the biological…”
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Parathyroid hormone-like protein is a secretory product of atrial myocytes
Published in The Journal of clinical investigation (01-08-1993)“…Parathyroid hormone-like protein (PLP) was originally identified from tumors associated with hypercalcemia. Recently, it has been found to be expressed in a…”
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Bone mineral density and indexes of bone metabolism in spinal cord injury
Published in American journal of physical medicine & rehabilitation (01-01-1998)“…We evaluated the pattern of osteoporosis after spinal cord injury, determined the time-frame of the changes, and elucidated the relationship among parathyroid…”
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High-efficiency non-viral transfection of primary chondrocytes and perichondrial cells for ex-vivo gene therapy to repair articular cartilage defects
Published in Osteoarthritis and cartilage (01-04-2001)“…Background Primary perichondrial cells and chondrocytes have been used to repair articular cartilage defects in tissue engineering studies involving various…”
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The short-term effects of conjugated estrogen on bone turnover in older women
Published in The journal of clinical endocrinology and metabolism (01-08-1994)“…Estrogen replacement therapy (ERT) prevents bone loss and fracture in early postmenopausal women, but its benefit for women over 70 yr of age has not been…”
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Parathyroid hormone-related protein in the cardiovascular system
Published in Endocrinology (Philadelphia) (01-07-1994)“…PTH-related protein (PTHrP) is expressed in a stretch-responsive manner in several types of smooth muscle. We previously demonstrated the production of PTHrP…”
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Transdermal iontophoretic delivery of salmon calcitonin
Published in International journal of pharmaceutics (25-04-2000)“…Electrically enhanced transdermal delivery of salmon calcitonin could be useful for chronic treatment of post-menopausal osteoporosis and other clinical…”
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1,25-dihydroxyvitamin D3 receptors in human leukocytes
Published in Science (American Association for the Advancement of Science) (16-09-1983)“…A 1,25-dihydroxyvitamin D3 receptor macromolecule was detected in peripheral mononuclear leukocytes from normal humans. This macromolecule was found to be…”
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Demineralization in tetraplegic and paraplegic man over time
Published in Spinal cord (01-04-1997)“…The aim of the present study was to compare bone mineral density (BMD in g/cm2) in the lumbar spine and three hip regions of male spinal cord injured subjects…”
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Densitometric patterns of spinal cord injury associated bone loss
Published in Spinal cord (01-06-1997)“…The purpose of the study was to use dual energy X-ray absorptiometry to measure bone mineral density (BMD) in the lumbar spine, the femoral neck, Ward's…”
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Parathyroid hormone-related protein: a potential autocrine growth regulator in human prostate cancer cell lines
Published in Urology (Ridgewood, N.J.) (01-05-1994)“…We recently demonstrated that parathyroid hormone-related protein (PTHrP) is widely expressed by human prostate cancer tissue, suggesting that PTHrP might be…”
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Prostate carcinoma : Production of bioactive factors
Published in Cancer (15-06-2000)“…Many molecular mechanisms regulate prostate carcinoma pathogenesis, proliferation, and progression to bone metastases. The basic molecular mechanisms are…”
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Immunoassay and immunohistology studies of chromogranin A as a neuroendocrine marker in patients with carcinoma of the prostate
Published in Urology (Ridgewood, N.J.) (01-07-1996)“…Objectives. Neuroendocrine differentiation in carcinoma of the prostate is characterized by the expression of neuroendocrine cell products such as chromogranin…”
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