Search Results - "DEBROSSE, C. W"
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A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent method
Published in RSC advances (01-01-2017)“…Our efforts to develop a scalable and divergent synthesis of cyclic di-nucleotide analog precursors have resulted in (1) an orthogonally protected di-amino…”
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Quality of life in paediatric eosinophilic oesophagitis: what is important to patients?
Published in Child : care, health & development (01-07-2012)“…Background and aims Current research outcomes in paediatric eosinophilic oesophagitis (EoE) are directed towards histological improvement with no attention to…”
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New Leukotriene B4 Receptor Antagonist: Leucettamine A and Related Imidazole Alkaloids from the Marine Sponge Leucetta microraphis
Published in Journal of natural products (Washington, D.C.) (01-01-1993)“…Three new imidazole alkaloids, leucettamines A [1] and B [2] and leucettamidine [3], have been isolated from the Palauan sponge Leucetta microraphis. Their…”
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Lithium quadrupole coupling constants and the structures of organic lithium compounds in solution
Published in Journal of the American Chemical Society (01-09-1987)Get full text
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Aggregation of lithium phenolates in weakly polar aprotic solvents
Published in Journal of the American Chemical Society (01-06-1983)Get full text
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Novel phloroglucinols from the plant Melicope sessiliflora (Rutaceae)
Published in Journal of organic chemistry (28-04-1989)Get full text
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Synthesis, conformation, and dopaminergic activity of 5,6-ethano-bridged derivatives of selective dopaminergic 3-benzazepines
Published in Journal of medicinal chemistry (01-08-1987)“…To probe the suggestion that D-1 (DA1) dopamine receptors might possess an accessory pi-binding site in a location complementary to a suitably oriented…”
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Allergy and eosinophil-associated gastrointestinal disorders (EGID)
Published in Current opinion in immunology (01-12-2008)“…Eosinophil-associated gastrointestinal disorders (EGIDs) are characterized by an inappropriate accumulation of eosinophils within the gastrointestinal tract…”
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Carbamoyl-phosphate synthetase II of the mammalian CAD protein: kinetic mechanism and elucidation of reaction intermediates by positional isotope exchange
Published in Biochemistry (Easton) (05-05-1987)“…The kinetic mechanism of carbamoyl-phosphate synthetase II from Syrian hamster kidney cells has been determined at pH 7.2 and 37 degrees C. Initial velocity,…”
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3-Amino-2-piperidinone-6-carboxylic acid. Molecular structures of cis and trans benzoyl derivatives
Published in International journal of peptide and protein research (01-10-1989)“…The cis (2a) and trans (2b) isomers of methyl 3-benzamido-2-piperidinone-6-carboxylate (Apca) were prepared and separated by fractional recrystallizations…”
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A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent methodDedicated to Prof. Al Padwa, a scholar and a sportsman who has reached pinnacles in both science and sport, on the occasion of his 80th birthday.Electronic supplementary information (ESI) available. See DOI: 10.1039/c7ra06045a
Published 07-06-2017“…Our efforts to develop a scalable and divergent synthesis of cyclic di-nucleotide analog precursors have resulted in (1) an orthogonally protected di-amino…”
Get full text
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A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent method† †Dedicated to Prof. Al Padwa, a scholar and a sportsman who has reached pinnacles in both science and sport, on the occasion of his 80th birthday. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c7ra06045a Click here for additional data file
Published in RSC advances (07-06-2017)“…Herein we present a scalable and divergent synthesis of cyclic di-nucleotide analog precursors facilitated by differentiated di-amino sugars and a Staudinger…”
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Novel phloroglucinols from the plant Melicope sessilifloro (Rutaceae)
Published in Journal of organic chemistry (01-04-1989)Get full text
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Conioidines A and B, Novel DNA-interacting Pyrrolidines from Chamaesaracha conioides
Published in Journal of natural products (Washington, D.C.) (01-05-1993)“…Two novel pyrrolidine compounds, conioidines A [1] and B [2], have been isolated from the Texas plant, Chamaesaracha conioides (Solanaceae). Their structures…”
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Chlorocardicin, a monocyclic beta-lactam from a Streptomyces sp. II. Isolation, physico-chemical properties and structure determination
Published in Journal of antibiotics (1985)“…Chlorocardicin, a novel monocyclic beta-lactam, was isolated from the fermentation broth of a Streptomyces sp. by the use of non-ionic porous resin and reverse…”
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1,3-Diarylindan-2-carboxylic Acids, Potent and Selective Non-Peptide Endothelin Receptor Antagonists
Published in Journal of medicinal chemistry (01-05-1994)Get full text
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A covalent nicotinamide adenine dinucleotide intermediate in the urocanase reaction
Published in Biochemistry (Easton) (01-01-1982)“…When imidazolepropionate, a competitive inhibitor of the nicotinamide adenine dinucleotide (NAD) dependent urocanase from Pseudomonas putida , binds to the…”
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Retrospective Identification of a Unique Cohort of Patients with Eosinophilic Esophagitis
Published in Journal of allergy and clinical immunology (01-02-2009)“…Chart review revealed that these patients ranged from 6 months to 21 years of age. 71% of these patients were male (N = 15/21) and 40% (N = 6/15) had a…”
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A study of variable hydration states in topotecan hydrochloride
Published in Journal of pharmaceutical and biomedical analysis (18-03-2006)“…Topotecan hydrochloride, a pharmaceutical compound developed as a treatment for cancer, exhibits variable hydration states in a crystalline solid form chosen…”
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