Search Results - "DEBLOIS, D"
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Differential regulation of Akt, caspases and MAP kinases underlies smooth muscle cell apoptosis during aortic remodelling in SHR treated with amlodipine
Published in British journal of pharmacology (01-08-2007)“…Background and purpose: The regression of aortic hypertrophy is initiated by a transient wave of smooth muscle cell (SMC) apoptosis in spontaneously…”
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Control of left ventricular mass by moxonidine involves reduced DNA synthesis and enhanced DNA fragmentation
Published in British journal of pharmacology (01-02-2008)“…Background and purpose: Left ventricular hypertrophy (LVH) is a maladaptive process associated with increased cardiovascular risk. Regression of LVH is…”
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Evidence That Nitric Oxide Regulates AT1-Receptor Agonist and Antagonist Efficacy in Rat Injured Carotid Artery
Published in Journal of cardiovascular pharmacology (01-05-2000)“…Vascular injury stimulates AT1-receptor expression and nitric oxide (NO) production in smooth muscle cells (SMCs). We examined the ability of AT1 agonists and…”
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Apoptosis in Barrett's oesophagus following antireflux surgery
Published in British journal of surgery (01-11-2002)“…Background: Intestinal metaplasia persists in Barrett's mucosa despite control of reflux. Tissue homeostasis is maintained by the balance between apoptosis and…”
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Hypotensive effects of Lys-des-Arg9-bradykinin and metabolically protected agonists of B1 receptors for kinins
Published in The Journal of pharmacology and experimental therapeutics (01-12-1991)“…B1 receptors for kinins are selectively stimulated by bradykinin (BK) or Lys-BK (kallidin) fragments without the C terminal arginine residue. The present study…”
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Pulse exposure to protein synthesis inhibitors enhances vascular responses to des‐Arg9‐bradykinin: possible role of interleukin‐1
Published in British journal of pharmacology (01-05-1991)“…1 The modulation of the spontaneous increase in contractile responses to des‐Arg9‐bradykinin (des‐Arg9‐BK) of rabbit aortic strips incubated in vitro was…”
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Effect of glucocorticoids, monokines and growth factors on the spontaneously developing responses of the rabbit isolated aorta to des‐Arg9‐bradykinin
Published in British journal of pharmacology (01-04-1988)“…1 The mechanisms modulating the spontaneous induction of contractile responses to agonists of the B1‐receptors for kinins have been studied by submitting the…”
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[3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein
Published in Apoptosis (London) (01-03-2003)“…[(3)H]-thymidine is commonly used to analyze the accumulation of [(3)H]-labeled chromatin fragments in cells undergoing apoptosis. This study shows that…”
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Effect of Phosphorothioated Oligonucleotides on Neointima Formation in the Rat Carotid Artery: Dissecting the Mechanism of Action
Published in Arteriosclerosis, thrombosis, and vascular biology (01-11-1997)“…Several studies have shown that single-dose administration of agents that inhibit medial cell replication, such as antisense oligonucleotides to cell…”
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058 Bradykinin B1 Receptor Antagonism Prevents Angiotensin II-Induced Erectile Dysfunction
Published in Journal of sexual medicine (01-02-2017)Get full text
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Synergism between the contractile effect of epidermal growth factor and that of des‐Arg9‐bradykinin or of α.‐thrombin in rabbit aortic rings
Published in British journal of pharmacology (01-04-1992)“…1 Rabbit aortic rings were used to test the possible contractile effects of growth factors and their interaction with other stimuli. A rapid potentiation of…”
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Endotoxin sensitization to kinin B 1 receptor agonist in a non‐human primate model: haemodynamic and pro‐inflammatory effects
Published in British journal of pharmacology (29-01-2009)“…Although endotoxaemia induces kinin B 1 receptors in several animal models, this condition is not documented in primates. This study examined the up‐regulation…”
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Smooth muscle DNA replication in response to angiotensin II is regulated differently in the neointima and media at different times after balloon injury in the rat carotid artery : Role of AT1 receptor expression
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-1996)“…We have reported that angiotensin II (Ang II) infusion to rats during the third and fourth weeks after vascular injury stimulates DNA replication in a larger…”
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Antiproliferative effect of brief exposure to cholera toxin in vascular smooth muscle cells: role of cAMP and protein kinase A
Published in Canadian journal of physiology and pharmacology (01-06-2001)“…The effect of cholera toxin (CTX), an activator of the adenylate cyclase-coupled G protein alpha(s) subunit, was studied on cultured vascular smooth muscle…”
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Cardiac mitochondrial NADP+-isocitrate dehydrogenase is inactivated through 4-hydroxynonenal adduct formation: an event that precedes hypertrophy development
Published in The Journal of biological chemistry (14-11-2003)“…Mitochondrial NADP+-isocitrate dehydrogenase activity is crucial for cardiomyocyte energy and redox status, but much remains to be learned about its role and…”
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Chronic alpha 1-adrenoreceptor stimulation increases DNA synthesis in rat arterial wall. Modulation of responsiveness after vascular injury
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-1996)“…Despite indirect evidence from studies using adrenergic antagonists or sympathectomy, catecholamines have never been shown directly to stimulate vascular…”
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Human interleukin‐1 induces a rapid relaxation of the rabbit isolated mesenteric artery
Published in British journal of pharmacology (01-06-1991)“…1 Strips of rabbit superior mesenteric artery, precontracted with phenylephrine, relaxed when exposed to human recombinant interleukin‐1 (IL‐1) of the α or β…”
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Effects of interleukin-1 receptor antagonist on three types of responses to interleukin-1 in rabbit isolated blood vessels
Published in Journal of cardiovascular pharmacology (01-05-1992)“…Interleukin-1 receptor antagonist (IRA) is a secretory product of human monocytes or related cell lines that acts as a pure interleukin-1 (IL-1) antagonist in…”
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Contractile Effect of the Chemotactic Factors f-Met-Leu-Phe and C5a on the Human Isolated Umbilical Artery: Role of Cyclooxygenase Products and Tissue Macrophages
Published in Circulation research (01-11-1990)“…Factors that are chemotactic for phagocytic leukocytes are known to elicit important acute circulatory changes, and the role of circulating leukocytes in these…”
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