Search Results - "DEBIES, Michael T"

Genetic basis of human breast cancer metastasis by Debies, M T, Welch, D R

“…Once cancer cells have spread and formed secondary masses, breast cancers are largely incurable even with state-of-the-art medicine. To improve diagnosis and…”
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Dormant Wnt-Initiated Mammary Cancer Can Participate in Reconstituting Functional Mammary Glands by Gestl, Shelley A., Leonard, Travis L., Biddle, Jessica L., Debies, Michael T., Gunther, Edward J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Ubiquitous Brms1 expression is critical for mammary carcinoma metastasis suppression via promotion of apoptosis by Cook, Leah M, Cao, Xuemei, Dowell, Alexander E, Debies, Michael T, Edmonds, Mick D, Beck, Benjamin H, Kesterson, Robert A, Desmond, Renee A, Frost, Andra R, Hurst, Douglas R, Welch, Danny R

“…Morbidity and mortality of breast cancer patients are drastically increased when primary tumor cells are able to spread to distant sites and proliferate to…”
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Predisposition to efficient mammary tumor metastatic progression is linked to the breast cancer metastasis suppressor gene Brms1 by HUNTER, Kent W, BROMAN, Karl W, LE VOYER, Thomas, LUKES, Luanne, COZMA, Diana, DEBIES, Michael T, ROUSE, Jessica, WELCH, Danny R

“…Tumor metastasis is one of the most important clinical aspects of neoplastic disease because patient mortality is frequently attributable to disseminated…”
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Suppression of murine mammary carcinoma metastasis by the murine ortholog of breast cancer metastasis suppressor 1 ( Brms1) by Samant, Rajeev S., Debies, Michael T., Hurst, Douglas R., Moore, Blake P., Shevde, Lalita A., Welch, Danny R.

“…The murine ortholog (Brms1) of human breast cancer metastasis suppressor 1 shares 95% identity to the human metastasis suppressor, BRMS1, in amino acid…”
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Identification and characterization of the murine ortholog (brms1) of breast‐cancer metastasis suppressor 1 (BRMS1) by Samant, Rajeev S., Debies, Michael T., Shevde, Lalita A., Verderame, Michael F., Welch, Danny R.

“…We have cloned a novel metastasis‐suppressor gene (BRMS1) by differential display, comparing metastatic human breast carcinoma cell line MDA‐MB‐435 to its…”
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Comparative sequence analysis in eight inbred strains of the metastasis modifier QTL candidate gene Brms1 by Park, Yeong-Gwan, Lukes, Luanne, Yang, Howard, Debies, Michael T, Samant, Rajeev S, Welch, Danny R, Lee, Maxwell, Hunter, Kent W

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Cu/Zn superoxide dismutase plays a role in angiogenesis by Marikovsky, Moshe, Nevo, Nava, Vadai, Ezra, Harris‐Cerruti, Catherine

“…Endothelial cells produce oxygen radicals spontaneously and this process is augmented by hypoxia/reoxygenation. Cu/Zn superoxide dismutase (SOD‐1) is an…”
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Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16Ink4a loss by Debies, Michael T., Gestl, Shelley A., Mathers, Jessica L., Mikse, Oliver R., Leonard, Travis L., Moody, Susan E., Chodosh, Lewis A., Cardiff, Robert D., Gunther, Edward J.

“…Breast cancers frequently progress or relapse during targeted therapy, but the molecular mechanisms that enable escape remain poorly understood. We elucidated…”
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Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by [p19.sup.Arf]/p53 pathway lesions but not [p16.sup.Ink4a] loss by Debies, Michael T, Gestl, Shelley A, Mathers, Jessica L, Mikse, Oliver R, Leonard, Travis L, Moody, Susan E, Chodosh, Lewis A, Cardiff, Robert D, Gunther, Edward J

“…Breast cancers frequently progress or relapse during targeted therapy, but the molecular mechanisms that enable escape remain poorly understood. We elucidated…”
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Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19Arf/p53 pathway lesions but not p16 Ink4a loss by Debies, Michael T, Gestl, Shelley A, Mathers, Jessica L, Mikse, Oliver R, Leonard, Travis L, Moody, Susan E, Chodosh, Lewis A, Cardiff, Robert D, Gunther, Edward J

“…Breast cancers frequently progress or relapse during targeted therapy, but the molecular mechanisms that enable escape remain poorly understood. We elucidated…”
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Tumor escape in a Wnt1-dependent mouse breast cancer model is enabled by p19^sup Arf^/p53 pathway lesions but not p16^sup Ink4a^ loss by Debies, Michael T, Gestl, Shelley A, Mathers, Jessica L, Mikse, Oliver R, Leonard, Travis L, Moody, Susan E, Chodosh, Lewis A, Cardiff, Robert D, Gunther, Edward J

“…Breast cancers frequently progress or relapse during targeted therapy, but the molecular mechanisms that enable escape remain poorly understood. We elucidated…”
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Genetic basis of human breast cancer metastasis: Breast cancer progression and metastasis by DEBIES, Michael T, WELCH, Danny R

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A small molecule antagonist of the α v β 3 integrin suppresses MDA-MB-435 skeletal metastasis by Harms, John F., Welch, Danny R., Samant, Rajeev S., Shevde, Lalita A., Miele, Mary E., Babu, Geetha R., Goldberg, Steven F., Gilman, Virginia R., Sosnowski, Donna M., Campo, Dianalee A., Gay, Carol V., Budgeon, Lynn R., Mercer, Robin, Jewell, Jennifer, Mastro, Andrea M., Donahue, Henry J., Erin, Nuray, Debies, Michael T., Meehan, William J., Jones, Amy L., Mbalaviele, Gabriel, Nickols, Allen, Christensen, Neil D., Melly, Robert, Beck, Lisa N., Kent, Julia, Rader, Randall K., Kotyk, John J., Pagel, M.D., Westlin, William F., Griggs, David W.

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A small molecule antagonist of the alpha(v)beta3 integrin suppresses MDA-MB-435 skeletal metastasis by Harms, John F, Welch, Danny R, Samant, Rajeev S, Shevde, Lalita A, Miele, Mary E, Babu, Geetha R, Goldberg, Steven F, Gilman, Virginia R, Sosnowski, Donna M, Campo, Dianalee A, Gay, Carol V, Budgeon, Lynn R, Mercer, Robin, Jewell, Jennifer, Mastro, Andrea M, Donahue, Henry J, Erin, Nuray, Debies, Michael T, Meehan, William J, Jones, Amy L, Mbalaviele, Gabriel, Nickols, Allen, Christensen, Neil D, Melly, Robert, Beck, Lisa N, Kent, Julia, Rader, Randall K, Kotyk, John J, Pagel, M D, Westlin, William F, Griggs, David W

“…Breast cancer is one of the most common malignancies affecting women in the United States and Europe. Approximately three out of every four women with breast…”
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