Search Results - "DEBETTE, Stéphanie"

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    Pathophysiology and risk factors of cervical artery dissection: what have we learnt from large hospital-based cohorts? by Debette, Stéphanie

    Published in Current opinion in neurology (01-02-2014)
    “…Cervical artery dissection (CeAD) is a major cause of ischemic stroke in young and middle-aged adults, although relatively uncommon in the community. Recent…”
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    Journal Article
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    Cervical-artery dissections: predisposing factors, diagnosis, and outcome by Debette, Stéphanie, MD, Leys, Didier, MD

    Published in Lancet neurology (01-07-2009)
    “…Summary Cervical-artery dissection (CAD) is a major cause of cerebral ischaemia in young adults and can lead to various clinical symptoms, some of which are…”
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    Genetic Risk Factors for Ischemic and Hemorrhagic Stroke by Chauhan, Ganesh, Debette, Stéphanie

    Published in Current cardiology reports (01-12-2016)
    “…Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel…”
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    Genetics of common cerebral small vessel disease by Bordes, Constance, Sargurupremraj, Muralidharan, Mishra, Aniket, Debette, Stéphanie

    Published in Nature reviews. Neurology (01-02-2022)
    “…Cerebral small vessel disease (cSVD) is a leading cause of ischaemic and haemorrhagic stroke and a major contributor to dementia. Covert cSVD, which is…”
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    Stroke Genetics: Discovery, Insight Into Mechanisms, and Clinical Perspectives by Debette, Stéphanie, Markus, Hugh S.

    Published in Circulation research (15-04-2022)
    “…Stroke is the second leading cause of death worldwide and a complex, heterogeneous condition. In this review, we provide an overview of the current knowledge…”
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    Extending understanding of the genetic architecture of cerebral small vessel disease using advanced imaging measures in UK Biobank by Debette, Stéphanie

    Published in Alzheimer's & dementia (01-12-2023)
    “…Cerebral small vessel disease (cSVD) is a leading cause of stroke and a major contributor to cognitive decline and dementia in the population (Debette JAMA…”
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    Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke by Montaner, Joan, Ramiro, Laura, Simats, Alba, Tiedt, Steffen, Makris, Konstantinos, Jickling, Glen C., Debette, Stephanie, Sanchez, Jean-Charles, Bustamante, Alejandro

    Published in Nature reviews. Neurology (01-05-2020)
    “…Despite many years of research, no biomarkers for stroke are available to use in clinical practice. Progress in high-throughput technologies has provided new…”
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    The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis by Debette, Stéphanie, Markus, H S

    Published in BMJ (26-07-2010)
    “…Objectives To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death.Design…”
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    Multiomic approaches to stroke: the beginning of a journey by Debette, Stéphanie, Chasman, Daniel I.

    Published in Nature reviews. Neurology (01-02-2024)
    “…Using integrative multiomics, a new study has shed light on the aetiology of ischaemic stroke. By probing the mechanisms underlying stroke, such approaches…”
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    Clinical Significance of Magnetic Resonance Imaging Markers of Vascular Brain Injury: A Systematic Review and Meta-analysis by Debette, Stéphanie, Schilling, Sabrina, Duperron, Marie-Gabrielle, Larsson, Susanna C, Markus, Hugh S

    Published in JAMA neurology (01-01-2019)
    “…Covert vascular brain injury (VBI) is highly prevalent in community-dwelling older persons, but its clinical and therapeutic implications are debated. To…”
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    Comment: Tackling shared genetic underpinnings of migraine and ischemic stroke by Debette, Stéphanie

    Published in Neurology (26-05-2015)
    “…In this large collaborative effort, Malik et al.[1] explore shared genetic variation underlying 2 common conditions: migraine and ischemic stroke (IS)…”
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    Early detection of white matter hyperintensities using SHIVA‐WMH detector by Tsuchida, Ami, Boutinaud, Philippe, Verrecchia, Violaine, Tzourio, Christophe, Debette, Stéphanie, Joliot, Marc

    Published in Human brain mapping (01-01-2024)
    “…White matter hyperintensities (WMHs) are well‐established markers of cerebral small vessel disease, and are associated with an increased risk of stroke,…”
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