Search Results - "DEBETTE, Stéphanie"
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PREDICTED VALUE OF CSF/MRI RESULTS IN THE THREE CITIES STUDY
Published in Alzheimer's & dementia (01-07-2016)Get full text
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Pathophysiology and risk factors of cervical artery dissection: what have we learnt from large hospital-based cohorts?
Published in Current opinion in neurology (01-02-2014)“…Cervical artery dissection (CeAD) is a major cause of ischemic stroke in young and middle-aged adults, although relatively uncommon in the community. Recent…”
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Cervical-artery dissections: predisposing factors, diagnosis, and outcome
Published in Lancet neurology (01-07-2009)“…Summary Cervical-artery dissection (CAD) is a major cause of cerebral ischaemia in young adults and can lead to various clinical symptoms, some of which are…”
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Genetic Risk Factors for Ischemic and Hemorrhagic Stroke
Published in Current cardiology reports (01-12-2016)“…Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel…”
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Genetics of common cerebral small vessel disease
Published in Nature reviews. Neurology (01-02-2022)“…Cerebral small vessel disease (cSVD) is a leading cause of ischaemic and haemorrhagic stroke and a major contributor to dementia. Covert cSVD, which is…”
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Stroke Genetics: Discovery, Insight Into Mechanisms, and Clinical Perspectives
Published in Circulation research (15-04-2022)“…Stroke is the second leading cause of death worldwide and a complex, heterogeneous condition. In this review, we provide an overview of the current knowledge…”
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Extending understanding of the genetic architecture of cerebral small vessel disease using advanced imaging measures in UK Biobank
Published in Alzheimer's & dementia (01-12-2023)“…Cerebral small vessel disease (cSVD) is a leading cause of stroke and a major contributor to cognitive decline and dementia in the population (Debette JAMA…”
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Stroke Genetics, Genomics, and Precision Medicine
Published in Stroke (1970) (01-08-2024)Get full text
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Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke
Published in Nature reviews. Neurology (01-05-2020)“…Despite many years of research, no biomarkers for stroke are available to use in clinical practice. Progress in high-throughput technologies has provided new…”
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The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis
Published in BMJ (26-07-2010)“…Objectives To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death.Design…”
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Extracellular matrix protein signature in cervical artery dissection: The key differentiator?
Published in Neurology (13-10-2020)Get full text
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Is Hypertension Associated With an Accelerated Aging of the Brain?
Published in Hypertension (Dallas, Tex. 1979) (01-05-2014)Get full text
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Multiomic approaches to stroke: the beginning of a journey
Published in Nature reviews. Neurology (01-02-2024)“…Using integrative multiomics, a new study has shed light on the aetiology of ischaemic stroke. By probing the mechanisms underlying stroke, such approaches…”
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Clinical Significance of Magnetic Resonance Imaging Markers of Vascular Brain Injury: A Systematic Review and Meta-analysis
Published in JAMA neurology (01-01-2019)“…Covert vascular brain injury (VBI) is highly prevalent in community-dwelling older persons, but its clinical and therapeutic implications are debated. To…”
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Comment: Tackling shared genetic underpinnings of migraine and ischemic stroke
Published in Neurology (26-05-2015)“…In this large collaborative effort, Malik et al.[1] explore shared genetic variation underlying 2 common conditions: migraine and ischemic stroke (IS)…”
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Early detection of white matter hyperintensities using SHIVA‐WMH detector
Published in Human brain mapping (01-01-2024)“…White matter hyperintensities (WMHs) are well‐established markers of cerebral small vessel disease, and are associated with an increased risk of stroke,…”
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Differential associations of plasma lipids with incident dementia and dementia subtypes in the 3C Study: A longitudinal, population-based prospective cohort study
Published in PLoS medicine (28-03-2017)“…Vascular risk factors have been proposed as important targets for the prevention of dementia. As lipid fractions represent easily modifiable targets, we…”
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Redefining common and rare HTRA1 variants as risk factors for polyvascular disease
Published in Nature cardiovascular research (01-06-2024)Get more information
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Neuroimaging standards for research into small vessel disease—advances since 2013
Published in Lancet neurology (01-07-2023)“…Cerebral small vessel disease (SVD) is common during ageing and can present as stroke, cognitive decline, neurobehavioural symptoms, or functional impairment…”
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