Search Results - "DEBERNARDIS, D"

Thymidylate synthase protein expression in colorectal cancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil by Aschele, C., Debernardis, D., Bandelloni, R., Cascinu, S., Catalano, V., Giordani, P., Barni, S., Turci, D., Drudi, G., Lonardi, S., Gallo, L., Maley, F., Monfardini, S.

“…Background: Different 5-fluorouracil (5-FU) schedules and/or biochemical modulators may result in different mechanisms of cytotoxicity, potentially affecting…”
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Schedule-dependent synergism between raltitrexed and irinotecan in human colon cancer cells in vitro by ASCHELE, C, BALDO, C, SOBRERO, A. F, DEBERNARDIS, D, BORNMANN, W. G, BERTINO, J. R

“…The quinazoline folate analogue raltitrexed (ZD1694; Tomudex) and the camptothecin derivative irinotecan are two new agents showing clinical activity against…”
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DDP-induced cytotoxicity is not influenced by p53 in nine human ovarian cancer cell lines with different p53 status by DE FEUDIS, P, DEBERNARDIS, D, BROGGINI, M, BECCAGLIA, P, VALENTI, M, SIRE, E. G, ARZANI, D, STANZIONE, S, PARODI, S, D'INCALCI, M, RUSSO, P

“…Nine human ovarian cancer cell lines that express wild-type (wt) or mutated (mut) p53 were used to evaluate the cytotoxicity induced by cisplatin (DDP). The…”
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Immunohistochemical determination of p53 protein does not predict clinical response in advanced colorectal cancer with low thymidylate synthase expression receiving a bolus 5-fluorouracil—leucovorin combination by Cascinu, S., Catalano, V., Aschele, C., Barni, S., Debernardis, D., Gallo, L., Bandelloni, R., Staccioli, M. P., Baldelli, A. M., Brenna, A., Valenti, A., Muretto, P., Catalano, G.

“…Background We assessed the hypothesis that a compromised p53 function could account for the non response of colon cancer patients with low thymidylate synthase…”
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Endogenous tumor necrosis factor enhances topoisomerase II inhibitors activity in human ovarian cancer cell lines by Debernardis, D, Stanzione, S, Ottoboni, C, Clerico, L, Mancuso, T, Parodi, S, Russo, P

“…In this study, we demonstrated that tumor necrosis factor (TNF), secreted endogenously by four human ovarian cancer cell lines (A2774, IGROV-1, OVCAR-8,…”
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In vitro synergism between 5-fluorouracil and natural beta interferon in human colon carcinoma cells by GUGLIELMI, A, ASCHELE, C, SOBRERO, A, MORI, A, BALDO, C, RUSSO, P, DEBERNARDIS, D, VALENTI, M, BRUNO, S, TAVERNA, M, ROSSO, R

“…The combination of 5-fluorouracil (FUra) plus IFN-beta was studied in vitro using a human colon carcinoma cell line, HCT-8. Continuous exposure to high…”
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Immunohistochemical Quantitation of Thymidylate Synthase Expression in Colorectal Cancer Metastases Predicts for Clinical Outcome to Fluorouracil-Based Chemotherapy by ASCHELE, C, DEBERNARDIS, D, CASAZZA, S, ANTONELLI, G, TUNESI, G, BALDO, C, LIONETTO, R, MALEY, F, SOBRERO, A

“…To determine whether immunohistochemical thymidylate synthase (TS) quantitation predicts for clinical outcome in patients with advanced colorectal cancer…”
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Thymidylate Synthase Protein Expression in Primary Colorectal Cancer Compared with the Corresponding Distant Metastases and Relationship with the Clinical Response to 5-Fluorouracil by ASCHELE, Carlo, DEBERNARDIS, Domizia, TUNESI, Gianni, MALEY, Frank, SOBRERO, Alberto

“…Thymidylate synthase (TS) expression in colorectal cancer metastases has been shown to predict for the clinical response to 5-fluorouracil. Because primary…”
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Thymidylate Synthase Protein Expression in Advanced Colon Cancer: Correlation with the Site of Metastasis and the Clinical Response to Leucovorin-modulated Bolus 5-Fluorouracil by CASCINU, S, ASCHELE, C, CATALANO, G, BARNI, S, DEBERNARDIS, D, BALDO, C, TUNESI, G, CATALANO, V, STACCIOLI, M. P, BRENNA, A, MURETTO, P

“…Recently, we have demonstrated that thymidylate synthase (TS) protein expression predicts for the clinical response to a regimen of infusional 5-fluorouracil…”
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p53 status does not affect sensitivity of human ovarian cancer cell lines to paclitaxel by DEBERNARDIS, D, SIRE, E. G, DE FEUDIS, P, VIKHANSKAYA, F, VALENTI, M, RUSSO, P, PARODI, S, D'INCALCI, M, BROGGINI, M

“…Nine human ovarian cancer cell lines that express wild-type (wt) or mutated p53 were used to evaluate the cytotoxicity induced by paclitaxel. The IC50…”
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Deleted in Colon Cancer Protein Expression in Colorectal Cancer Metastases: A Major Predictor of Survival in Patients With Unresectable Metastatic Disease Receiving Palliative Fluorouracil-Based Chemotherapy by ASCHELE, Carlo, DEBERNARDIS, Domizia, LONARDI, Sara, BANDELLONI, Roberto, CASAZZA, Stefania, MONFARDINI, Silvio, GALLO, Luigi

“…To determine whether deleted in colon cancer (DCC) protein expression in colorectal cancer (CRC) metastases could predict outcome to palliative fluorouracil…”
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Surgical fixation of periprosthetic humeral shaft fracture about a short-stem anatomic total shoulder arthroplasty with a proximal humeral locking plate: surgical technique and report of 3 cases by Santoro, Adam, DeBernardis, Dennis, Chen, Raymond, Hendy, Benjamin, Lazarus, Mark

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Biologic graft augmentation for glenoid bone loss in conversion of failed anatomic to reverse shoulder arthroplasty: a systematic review by Fliegel, Brian E., DeBernardis, Dennis, Ford, Elizabeth, Favorito, Paul, McMillan, Sean

“…Glenoid bone loss presents a challenging dilemma, particularly in the setting of failed arthroplasty requiring conversion to a reverse total shoulder…”
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Thymidylate synthase protein expression in colorectalcancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil by Aschele, C., Debernardis, D., Bandelloni, R., Cascinu, S., Catalano, V., Giordani, P., Barni, S., Turci, D., Drudi, G., Lonardi, S., Gallo, L., Maley, F., Monfardini, S.

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Midterm outcomes and survivorship of arthroscopic elbow debridement: a comparison of posttraumatic versus primary degenerative osteoarthritis by DeBernardis, Dennis A., Santoro, Adam J., Minissale, Nicholas J., Kirsch, Jacob M., Cheesman, Quincy T., Alberta, Frank G., Austin, Luke S.

“…Arthroscopic debridement is an effective means of surgical management of both degenerative osteoarthritis (DOA) and posttraumatic arthritis (PTA) of the elbow…”
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284 DCC protein expression in colorectal cancer (CRC) metastases and lack of response to biochemically-modulated 5-fluorouracil (FU) among patients (pts) with low level of thymidylate synthase (TS) protein expression by Lonardi, S., Casazza, S., Debernardis, D., Garrè, S., Gallo, L., Monfardini, S., Aschele, C.

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Thymidylate synthase (TS) protein expression in advanced colon cancer: correlation with the site of metastasis and the clinical response to leucovorin-modulated bolus 5-fluorouracil (5FU) by Cascinu, S., Aschele, C., Barni, S., Debernardis, D., Baldo, C., Tunesi, G., Catalano, V., Giordani, P., Baldelli, A.M., Catalano, G.

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Interactions between taxol and camptothecin by Debernardis, D, Cimoli, G, Parodi, S, Russo, P

“…Taxol is an antitumor drug which, as its mechanism of action, promotes microtubule assembly in vitro. Camptothecin (CPT) is an anticancer agent with the…”
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NADPH diaphorase activity around the suprachiasmatic nucleus in rat brain by Lupi, D, Debernardis, D, Vallerga, S, Morgan, P J, Djamgoz, M B

“…The 'nicotinamide adenine dinucleotide phosphate diaphorase' histochemical technique was used as a marker of neuronal nitric oxide synthase to assess the…”
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Interferon-α or β potentiate platinum analogous in human glioblastoma cell lines by Stanzione, Sabrina, Cimoli, Guido, Debernardis, Domizia, Michelotti, Andrea, Conte, PierFranco, Parodi, Silvio, Russo, Patrizia

“…The effect of interferon-α or β on platinum analogues [cisplatin (CDDP) and carboplatin] cytotoxicity was studied in four glioblastoma cell lines (U373MG,…”
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