Search Results - "DE WAELE, Jan J"

Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper by Abdul-Aziz, Mohd H., Alffenaar, Jan-Willem C., Bassetti, Matteo, Bracht, Hendrik, Dimopoulos, George, Marriott, Deborah, Neely, Michael N., Paiva, Jose-Artur, Pea, Federico, Sjovall, Fredrik, Timsit, Jean F., Udy, Andrew A., Wicha, Sebastian G., Zeitlinger, Markus, De Waele, Jan J., Roberts, Jason A.

“…Purpose This Position Paper aims to review and discuss the available data on therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in…”
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Antimicrobial stewardship, therapeutic drug monitoring and infection management in the ICU: results from the international A- TEAMICU survey by Lanckohr, Christian, Boeing, Christian, De Waele, Jan J., de Lange, Dylan W., Schouten, Jeroen, Prins, Menno, Nijsten, Maarten, Povoa, Pedro, Morris, Andrew Conway, Bracht, Hendrik

“…Background Severe infections and multidrug-resistant pathogens are common in critically ill patients. Antimicrobial stewardship (AMS) and therapeutic drug…”
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Pathogen-based target attainment of optimized continuous infusion dosing regimens of piperacillin-tazobactam and meropenem in surgical ICU patients: a prospective single center observational study by De Corte, Thomas, Verhaeghe, Jarne, Dhaese, Sofie, Van Vooren, Sarah, Boelens, Jerina, G. Verstraete, Alain, Stove, Veronique, Ongenae, Femke, De Bus, Liesbet, Depuydt, Pieter, Van Hoecke, Sofie, J. De Waele, Jan

“…Background Several studies have indicated that commonly used piperacillin-tazobactam (TZP) and meropenem (MEM) dosing regimens lead to suboptimal plasma…”
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Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017 by Vincent, Jean-Louis, Sakr, Yasser, Singer, Mervyn, Martin-Loeches, Ignacio, Machado, Flavia R, Marshall, John C, Finfer, Simon, Pelosi, Paolo, Brazzi, Luca, Aditianingsih, Dita, Timsit, Jean-François, Du, Bin, Wittebole, Xavier, Máca, Jan, Kannan, Santhana, Gorordo-Delsol, Luis A, De Waele, Jan J, Mehta, Yatin, Bonten, Marc J. M, Khanna, Ashish K, Kollef, Marin, Human, Mariesa, Angus, Derek C

“…IMPORTANCE: Infection is frequent among patients in the intensive care unit (ICU). Contemporary information about the types of infections, causative pathogens,…”
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Antimicrobial stewardship in ICUs during the COVID-19 pandemic: back to the 90s? by De Waele, Jan J., Derde, Lennie, Bassetti, Matteo

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Antimicrobial de-escalation as part of antimicrobial stewardship in intensive care: no simple answers to simple questions—a viewpoint of experts by De Waele, Jan J., Schouten, Jeroen, Beovic, Bojana, Tabah, Alexis, Leone, Marc

“…Antimicrobial de-escalation (ADE) is defined as the discontinuation of one or more components of combination empirical therapy, and/or the change from a…”
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Selective digestive decontamination - Pro by De Waele, Jan J., Leroux-Roels, Isabel, Depuydt, Pieter

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Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome: a systematic review and meta-analysis by Van Damme, Lana, De Waele, Jan J

“…Decompressive laparotomy has been advised as potential treatment for abdominal compartment syndrome (ACS) when medical management fails; yet, the effect on…”
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ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients by Martin-Loeches, Ignacio, Antonelli, Massimo, Cuenca-Estrella, Manuel, Dimopoulos, George, Einav, Sharon, De Waele, Jan J., Garnacho-Montero, Jose, Kanj, Souha S., Machado, Flavia R., Montravers, Philippe, Sakr, Yasser, Sanguinetti, Maurizio, Timsit, Jean-Francois, Bassetti, Matteo

“…Introduction The term invasive candidiasis (IC) refers to both bloodstream and deep-seated invasive infections, such as peritonitis, caused by Candida species…”
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A Clinician's Guide to Management of Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Critically Ill Patients by De Laet, Inneke E, Malbrain, Manu L N G, De Waele, Jan J

“…This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online…”
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A Systematic Review of the Definitions, Determinants, and Clinical Outcomes of Antimicrobial De-escalation in the Intensive Care Unit by Tabah, Alexis, Cotta, Menino Osbert, Garnacho-Montero, Jose, Schouten, Jeroen, Roberts, Jason A., Lipman, Jeffrey, Tacey, Mark, Timsit, Jean-François, Leone, Marc, Zahar, Jean Ralph, De Waele, Jan J.

“…Antimicrobial de-escalation (ADE) is a strategy to reduce the spectrum of antimicrobials and aims to prevent the emergence of bacterial resistance. We present…”
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How I search for a sepsis source by De Waele, Jan J, Sakr, Yasser

“…Keywords: Sepsis, Septic shock, Infection, Diagnosis, Antibiotic therapy…”
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The Sequential Organ Failure Assessment (SOFA) Score: has the time come for an update? by Moreno, Rui, Rhodes, Andrew, Piquilloud, Lise, Hernandez, Glenn, Takala, Jukka, Gershengorn, Hayley B, Tavares, Miguel, Coopersmith, Craig M, Myatra, Sheila N, Singer, Mervyn, Rezende, Ederlon, Prescott, Hallie C, Soares, Márcio, Timsit, Jean-François, de Lange, Dylan W, Jung, Christian, De Waele, Jan J, Martin, Greg S, Summers, Charlotte, Azoulay, Elie, Fujii, Tomoko, McLean, Anthony S, Vincent, Jean-Louis

“…The Sequential Organ Failure Assessment (SOFA) score was developed more than 25 years ago to provide a simple method of assessing and monitoring organ…”
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Meropenem and piperacillin/tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used? by Carlier, Mieke, Carrette, Sofie, Roberts, Jason A, Stove, Veronique, Verstraete, Alain, Hoste, Eric, Depuydt, Pieter, Decruyenaere, Johan, Lipman, Jeffrey, Wallis, Steven C, De Waele, Jan J

“…Correct antibiotic dosing remains a challenge for the clinician. The aim of this study was to assess the influence of augmented renal clearance on…”
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Towards adequate and automated antibiotic dosing by Janssen, Alexander, De Waele, Jan J., Elbers, Paul W. G.

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Importance of timely and adequate source control in sepsis and septic shock by De Waele, Jan J.

“…Source control is defined as the physical measures undertaken to eliminate the source of infection and control ongoing contamination, as well as restore…”
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Augmented renal clearance is a common finding with worse clinical outcome in critically ill patients receiving antimicrobial therapy by Claus, Barbara O.M., PharmD, Hoste, Eric A., MD, PhD, Colpaert, Kirsten, MD, Robays, Hugo, PharmD, Decruyenaere, Johan, MD, PhD, De Waele, Jan J., MD, PhD

“…Abstract Introduction We describe incidence and patient factors associated with augmented renal clearance (ARC) in adult intensive care unit (ICU) patients…”
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Comparison of different equations to assess glomerular filtration in critically ill patients by Carlier, Mieke, Dumoulin, Alexander, Janssen, Alexander, Picavet, Sven, Vanthuyne, Steve, Van Eynde, Ria, Vanholder, Raymond, Delanghe, Joris, De Schoenmakere, Gert, De Waele, Jan J., Hoste, Eric A. J.

“…Purpose To evaluate equations for estimation of glomerular filtration rate (GFR) and measured urinary creatinine clearance, compared to measured GFR in…”
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Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients: a retrospective observational study by De Bus, Liesbet, Denys, Wouter, Catteeuw, Julie, Gadeyne, Bram, Vermeulen, Karel, Boelens, Jerina, Claeys, Geert, De Waele, Jan J., Decruyenaere, Johan, Depuydt, Pieter O.

“…Purpose Antibiotic de-escalation is promoted to limit prolonged exposure to broad-spectrum antibiotics, but proof that it prevents the emergence of resistance…”
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Clinical outcomes in combination versus mono antibiotic therapy in ICU admitted patients with a suspected infection - A substudy of the DIANA study by Tanha, Nima, Areskog Lejbman, Ilja, De Bus, Liesbet, De Pascale, Gennaro, Garnacho-Montero, José, Leone, Marc, Fujitan, Shigeki, De Waele, Jan J, Torisson, Gustav, Sjövall, Fredrik

“…In a retrospective cohort study of intensive care unit (ICU) admitted adult patients with suspected or confirmed infection, associations between combination…”
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