Search Results - "DE VERA, A"
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Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression
Published in Molecules (Basel, Switzerland) (30-11-2019)“…The overexpression of ABC transporters induced by anticancer drugs has been found to be the main cause of multidrug resistance. It is actually also a strategy…”
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2
Colorectal Cancer and Onset of Anxiety and Depression: A Systematic Review and Meta-Analysis
Published in Current oncology (Toronto) (15-11-2022)“…Research suggests that colorectal cancer (CRC) is associated with mental health disorders, primarily anxiety and depression. To synthesize this evidence, we…”
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Immediate and past cumulative effects of oral glucocorticoids on the risk of acute myocardial infarction in rheumatoid arthritis: a population-based study
Published in Rheumatology (Oxford, England) (01-01-2013)“…To determine the effect of glucocorticoids (GCs) on acute myocardial infarction (MI) risk in patients with RA. Using administrative health data, we conducted a…”
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Mental health in people living with and beyond colorectal cancer: A patient‐oriented constructivist grounded theory
Published in Cancer medicine (Malden, MA) (01-09-2024)“…Background With the burden of colorectal cancer in Canada, there is a need to address the psycho‐oncologic challenges, including mental health. This study aims…”
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Recent and historical pollution legacy in high altitude Lake Marboré (Central Pyrenees): A record of mining and smelting since pre-Roman times in the Iberian Peninsula
Published in The Science of the total environment (10-01-2021)“…We have analyzed potential harmful trace elements (PHTE; Pb, Hg, Zn, As and Cu) on sediment cores retrieved from lake Marboré (LM) (2612 m a.s.l, 42°41′N; 0°…”
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Perspectives and experiences with telepharmacy among pharmacists in Canada: A cross-sectional survey
Published in Pharmacy practice : official journal of the GRIPP (Global Research Institute of Pharmacy Practice) (01-01-2022)“…Objective: This study aims to understand Canadian pharmacists’ use, experiences, and perspectives of telepharmacy. Methods: We conducted a cross-sectional…”
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7
Impact of MYC on Anti-Tumor Immune Responses in Aggressive B Cell Non-Hodgkin Lymphomas: Consequences for Cancer Immunotherapy
Published in Cancers (20-10-2020)“…Patients with MYC overexpressing high grade B cell lymphoma (HGBL) face significant dismal prognosis after treatment with standard immunochemotherapy regimens…”
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Impact of statin adherence on cardiovascular disease and mortality outcomes: a systematic review
Published in British journal of clinical pharmacology (01-10-2014)“…Aims While suboptimal adherence to statin medication has been quantified in real‐world patient settings, a better understanding of its impact is needed,…”
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9
Medication Nonadherence in Systemic Lupus Erythematosus: A Systematic Review
Published in Arthritis care & research (2010) (01-11-2017)“…Objective Medication nonadherence has not been well characterized in systemic lupus erythematosus (SLE). Our objective was to a conduct a systematic review of…”
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Trends in the epidemiology of young-onset colorectal cancer: a worldwide systematic review
Published in BMC cancer (06-04-2020)“…Recent data suggest that the risk of young-onset colorectal cancer (yCRC), in adults less than 50 years of age, is increasing. To confirm findings and identify…”
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11
Epcoritamab induces potent anti-tumor activity against malignant B-cells from patients with DLBCL, FL and MCL, irrespective of prior CD20 monoclonal antibody treatment
Published in Blood cancer journal (New York) (18-02-2021)“…Epcoritamab (DuoBody-CD3xCD20, GEN3013) is a novel bispecific IgG1 antibody redirecting T-cells toward CD20 + tumor cells. Here, we assessed the preclinical…”
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How patients with gout become engaged in disease management: a constructivist grounded theory study
Published in Arthritis research & therapy (01-06-2018)“…Prior qualitative research on gout has focused primarily on barriers to disease management. Our objective was to use patients' perspectives to construct an…”
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Immuno-oncology agent IPI-549 is a modulator of P-glycoprotein (P-gp, MDR1, ABCB1)-mediated multidrug resistance (MDR) in cancer: In vitro and in vivo
Published in Cancer letters (01-02-2019)“…Phosphoinositide 3-kinase gamma isoform (PI3Kγ) plays a critical role in myeloid-derived cells of the immunosuppressive tumor microenvironment. IPI-549, a…”
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14
Reliability and Validity of an Internet-based Questionnaire Measuring Lifetime Physical Activity
Published in American journal of epidemiology (15-11-2010)“…Lifetime exposure to physical activity is an important construct for evaluating associations between physical activity and disease outcomes, given the long…”
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What are the experiences of colorectal cancer patients with biomarker testing in Canada?: a mixed methods study
Published in BMC cancer (31-08-2024)“…Molecular or biomarker testing to guide targeted treatments for colorectal cancer (CRC) has advanced care, specifically by improving treatment specificity. Our…”
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The impact of introducing multidisciplinary care assessments on access to rheumatology care in British Columbia: an interrupted time series analysis
Published in BMC health services research (11-03-2022)“…In 2011 the British Columbia (BC) Ministry of Health introduced a new fee-for-service billing code that allowed "Multidisciplinary Care Assessment" (MCA). This…”
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Assessing how health information needs of individuals with colorectal cancer are met across the care continuum: an international cross-sectional survey
Published in BMC cancer (27-10-2020)“…Studies evaluating health information needs in colorectal cancer (CRC) lack specificity in terms of study samples involving patients. We assessed how health…”
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Study of the costs and morbidities of late-preterm birth
Published in Archives of disease in childhood. Fetal and neonatal edition (01-09-2012)“…To compare late-preterm infants (33-36 weeks) with term infants (≥37 weeks) on incidence of morbidities in the first 3 years of life and healthcare costs…”
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Reporting of determinants of health inequities and participant characteristics in randomized controlled trials of juvenile idiopathic arthritis in Canada: a scoping review
Published in Pediatric rheumatology online journal (06-11-2023)“…Abstract Background Juvenile Idiopathic Arthritis (JIA) is the most common form of childhood inflammatory arthritis. The disease burden of JIA is substantial…”
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"The medications are the decision-makers…" Making reproductive and medication use decisions among female patients with rheumatoid arthritis: a constructivist grounded theory
Published in Arthritis research & therapy (22-01-2022)“…To examine how female patients with RA form decisions about having children, pregnancy, and medication use. We employed a constructivist grounded theory design…”
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