Search Results - "DE THONEL, A"

HSP110 promotes colorectal cancer growth through STAT3 activation by Berthenet, K, Bokhari, A'dem, Lagrange, A, Marcion, G, Boudesco, C, Causse, S, De Thonel, A, Svrcek, M, Goloudina, A R, Dumont, S, Hammann, A, Biard, D S, Demidov, O N, Seigneuric, R, Duval, A, Collura, A, Jego, G, Garrido, C

“…Heat shock protein 110 (HSP110) is induced by different stresses and, through its anti-apoptotic and chaperoning properties, helps cells survive these adverse…”
Get full text

Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E by Andrieu, C, Taieb, D, Baylot, V, Ettinger, S, Soubeyran, P, De-Thonel, A, Nelson, C, Garrido, C, So, A, Fazli, L, Bladou, F, Gleave, M, Iovanna, J L, Rocchi, P

“…One strategy to improve therapies in advanced prostate cancer (PC) involves targeting genes that are activated by androgen withdrawal to delay the emergence of…”
Get full text

Heat shock protein 27 is involved in SUMO-2 3 modification of heat shock factor 1 and thereby modulates the transcription factor activity by Brunet Simioni, M, De Thonel, A, Hammann, A, Joly, A L, Bossis, G, Fourmaux, E, Bouchot, A, Landry, J, Piechaczyk, M, Garrido, C

“…Heat shock protein 27 (HSP27) accumulates in stressed cells and helps them to survive adverse conditions. We have already shown that HSP27 has a function in…”
Get full text

Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes by Jego, G, Lanneau, D, De Thonel, A, Berthenet, K, Hazoumé, A, Droin, N, Hamman, A, Girodon, F, Bellaye, P-S, Wettstein, G, Jacquel, A, Duplomb, L, Le Mouël, A, Papanayotou, C, Christians, E, Bonniaud, P, Lallemand-Mezger, V, Solary, E, Garrido, C

“…In addition to their cytoprotective role in stressful conditions, heat shock proteins (HSPs) are involved in specific differentiation pathways, for example, we…”
Get full text

Regulation of death receptors—Relevance in cancer therapies by de Thonel, A., Eriksson, J.E.

“…Apoptosis is an essential non-inflammatory mechanism for cell removal, which occurs during both physiological and pathological conditions. Apoptosis is…”
Get full text

TNFα stimulates NKG2D-mediated lytic activity of acute myeloid leukemic cells by GUILLOTON, F, DE THONEL, A, JEAN, C, DEMUR, C, MANSAT-DE MAS, V, LAURENT, G, QUILLET-MARY, A

“…The mechanism by which leukemic cells interfere with normal hematopoiesis remains unclear. We show here that, whereas the leukemic KG1a cells are naturally…”
Get full text

Regulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cells by de Thonel, A, Hazoumé, A, Kochin, V, Isoniemi, K, Jego, G, Fourmaux, E, Hammann, A, Mjahed, H, Filhol, O, Micheau, O, Rocchi, P, Mezger, V, Eriksson, J E, Rangnekar, V M, Garrido, C

“…The proapoptotic protein, prostate apoptosis response-4 (Par-4), acts as a tumor suppressor in prostate cancer cells. The serine/threonine kinase casein kinase…”
Get full text

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells by Chalmin, Fanny, Ladoire, Sylvain, Mignot, Grégoire, Vincent, Julie, Bruchard, Mélanie, Remy-Martin, Jean-Paul, Boireau, Wilfrid, Rouleau, Alain, Simon, Benoit, Lanneau, David, De Thonel, Aurélie, Multhoff, Gabriele, Hamman, Arlette, Martin, François, Chauffert, Bruno, Solary, Eric, Zitvogel, Laurence, Garrido, Carmen, Ryffel, Bernhard, Borg, Christophe, Apetoh, Lionel, Rébé, Cédric, Ghiringhelli, François

“…Myeloid-derived suppressor cells (MDSCs) have been identified in humans and mice as a population of immature myeloid cells with the ability to suppress T cell…”
Get full text

HSP27 controls GATA-1 protein level during erythroid cell differentiation by de Thonel, Aurelie, Vandekerckhove, Julie, Lanneau, David, Selvakumar, Subramaniam, Courtois, Geneviève, Hazoume, Adonis, Brunet, Mathilde, Maurel, Sebastien, Hammann, Arlette, Ribeil, Jean Antoine, Zermati, Yael, Gabet, Anne Sophie, Boyes, Joan, Solary, Eric, Hermine, Olivier, Garrido, Carmen

“…Heat shock protein 27 (HSP27) is a chaperone whose cellular expression increases in response to various stresses and protects the cell either by inhibiting…”
Get full text

Binding and Phosphorylation of Par-4 by Akt Is Essential for Cancer Cell Survival by Goswami, Anindya, Burikhanov, Ravshan, de Thonel, Aurelie, Fujita, Naoya, Goswami, Mamta, Zhao, Yanming, Eriksson, John E., Tsuruo, Takashi, Rangnekar, Vivek M.

“…Activation of the PI3K-Akt pathway by loss of tumor suppressor PTEN (phosphatase and tensin homolog deleted on chromosome 10) function, increased growth factor…”
Get full text

Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes by Jego, G, Lanneau, D, de Thonel, A, Berthenet, K, Hazoumé, A, Droin, N, Hamman, A, Girodon, F, Bellaye, P-S, Wettstein, G, Jacquel, A, Duplomb, L, Le Mouël, A, Papanayotou, C, Christians, E, Bonniaud, P, Lallemand-Mezger, V, Solary, E, Garrido, C

Get full text

Protein kinase C ζ  associates with death inducing signaling complex and regulates Fas ligand-induced apoptosis by Leroy, Ingrid, de Thonel, Aurélie, Laurent, Guy, Quillet-Mary, Anne

“…Previous studies have shown that Protein kinase C (PKC) stimulation may interfere with Fas signaling pathway and Fas ligand (FasL)-induced apoptosis. In this…”
Get full text

Role of protein kinase C ζ isoform in Fas resistance of immature myeloid KG1a leukemic cells by de Thonel, Aurélie, Bettaı̈eb, Ali, Jean, Christine, Laurent, Guy, Quillet-Mary, Anne

“…Leukemic CD34+ immature acute myeloid leukemia (AML) cells express Fas receptor but are frequently resistant to Fas agonistic reagents. Fas plays an important…”
Get full text

TNFalpha stimulates NKG2D-mediated lytic activity of acute myeloid leukemic cells by Guilloton, F, de Thonel, A, Jean, C, Demur, C, Mansat-De Mas, V, Laurent, G, Quillet-Mary, A

“…The mechanism by which leukemic cells interfere with normal hematopoiesis remains unclear. We show here that, whereas the leukemic KG1a cells are naturally…”
Get full text

TNFα stimulates NKG2D-mediated lytic activity of acute myeloid leukemic cells by Guilloton, F, de Thonel, A, Jean, C, Demur, C, Mansat-de Mas, V, Laurent, G, Quillet-Mary, A

Get full text

TNF stimulates NKG2D-mediated lytic activity of acute myeloid leukemic cells by Guilloton, F, de Thonel, A, Jean, C, Demur, C, V Mansat-De Mas, Laurent, G, Quillet-Mary, A

“…The mechanism by which leukemic cells interfere with normal hematopoiesis remains unclear. We show here that, whereas the leukemic KG1a cells are naturally…”
Get full text

Protein kinase C‐ζ overexpression induces erythroid phenotype in the monocytic leukaemia cell line U937 by Mansat‐De Mas, Véronique, De Thonel, Aurélie, Gaulin, Vanessa, Demur, Cécile, Laurent, Guy, Quillet‐Mary, Anne

“…Previous studies have established that protein kinase C‐ζ (PKC‐ζ) is critical for neuronal cell differentiation. However, the role of PKC‐ζ in haematopoietic…”
Get full text

Acute myeloblastic leukemic cells acquire cellular cytotoxicity under genotoxic stress: implication of granzyme B and perforin by Bruno, Alain Pierre, Lautier, Dominique, d'Orgeix, Aurélie de Thonel, Laurent, Guy, Quillet-Mary, Anne

“…Granzyme B (GrB) and perforin (PFN) are the major components of cytoplasmic granules contained in immune cellular effectors. The granule secretory pathway is…”
Get full text