Search Results - "DE PAULIS, T"

Sodium-dependent isomerization of dopamine D-2 receptors characterized using [125I]epidepride, a high-affinity substituted benzamide ligand by Neve, K A, Henningsen, R A, Kinzie, J M, De Paulis, T, Schmidt, D E, Kessler, R M, Janowsky, A

“…We have characterized the in vitro binding of a new ligand, [125I]epidepride, and used this substituted benzamide to assess the sensitivity of dopamine D-2…”
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Extrastriatal dopamine D2 receptors: distribution, pharmacological characterization and region-specific regulation by clozapine by Janowsky, A, Neve, K A, Kinzie, J M, Taylor, B, de Paulis, T, Belknap, J K

“…The distribution of dopamine D2 receptors in the rat brain was determined by quantitative autoradiography of the binding of [125I]epidepride and the effects of…”
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Effect of Roasting on the Formation of Chlorogenic Acid Lactones in Coffee by Farah, Adriana, de Paulis, Tomas, Trugo, Luiz C, Martin, Peter R

“…Of all plant constituents, coffee has one of the highest concentrations of chlorogenic acids. When roasting coffee, some of these are transformed into…”
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High Affinity Dopamine D2 Receptor Radioligands. 1. Regional Rat Brain Distribution of Iodinated Benzamides by Kessler, Robert M, Ansari, M. Sib, de Paulis, Tomas, Schmidt, Dennis E, Clanton, Jeffrey A, Smith, Howard E, Manning, Ronald G, Gillespie, David, Ebert, Michael H

“…Five 125I-labeled substituted benzamides, which are close structural analogues of (S)-sulpiride, eticlopride, and isoremoxipride, were evaluated for their…”
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Chlorogenic Acids and Lactones in Regular and Water-Decaffeinated Arabica Coffees by Farah, Adriana, de Paulis, Tomas, Moreira, Daniel P, Trugo, Luiz C, Martin, Peter R

“…The market for decaffeinated coffees has been increasingly expanding over the years. Caffeine extraction may result in losses of other compounds such as…”
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High affinity dopamine D2 receptor radioligands. 2. [125I]epidepride, a potent and specific radioligand for the characterization of striatal and extrastriatal dopamine D2 receptors by Kessler, R M, Ansari, M S, Schmidt, D E, de Paulis, T, Clanton, J A, Innis, R, al-Tikriti, M, Manning, R G, Gillespie, D

“…Epidepride, (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2,3-dimethoxybenzamide+ ++, the iodine analogue of isoremoxipride (FLB 457), was found to be a very…”
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Dosimetry of Iodine-123-Epidepride: A Dopamine D2 Receptor Ligand by Votaw, John R, Ansari, M. Sib, Mason, N. Scott, Schmidt, Dennis, de Paulis, Tomas, Holburn, George, Clanton, Jeff A, Votaw, Delicia B, Manning, Ronald G, Kessler, Robert M

“…Substituted benzamides have been shown to have very high affinity and specificity for the dopamine D2 receptor. One of these is radiolabeled epidepride, an…”
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Antioxidant effects of dihydrocaffeic acid in human EA.hy926 endothelial cells by Huang, Junjun, de Paulis, Tomas, May, James M.

“…Dihydrocaffeic acid (DHCA) is a metabolite of caffeic acid with potent antioxidant properties. Since DHCA has been detected in human plasma following coffee…”
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Quinides of roasted coffee enhance insulin action in conscious rats by Shearer, Jane, Farah, Adriana, de Paulis, Tomas, Bracy, Deanna P, Pencek, R Richard, Graham, Terry E, Wasserman, David H

“…Consumption of large amounts of coffee has been shown to decrease the incidence of type 2 diabetes. However, the specific compounds and mechanisms responsible…”
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Metabolism of zimelidine in rat, dog and man. Identification and synthesis of the principal metabolites by Lundström, J, Högberg, T, Gosztonyi, T, de Paulis, T

“…Several metabolites of (Z)-3-(4-bromophenyl)-N,N-dimethyl-3-(3-pyridyl)allylamine (zimelidine) were isolated from urine of rat and dog after administration of…”
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Comprehensive analysis of major and minor chlorogenic acids and lactones in economically relevant Brazilian coffee cultivars by Perrone, D, Farah, A, Donangelo, C.M, De Paulis, T, Martin, P.R

“…Coffee is the most consumed beverage in the world and a significant source of phenolic compounds, particularly chlorogenic acids (CGA). During coffee roasting,…”
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Dicinnamoylquinides in roasted coffee inhibit the human adenosine transporter by de Paulis, Tomas, Schmidt, Dennis E, Bruchey, Aleksandra K, Kirby, Michael T, McDonald, Michael P, Commers, Patricia, Lovinger, David M, Martin, Peter R

“…Preliminary screening of a minor, non-xanthine constituent of roasted coffee, 3,4-diferuloyl-1,5-quinolactone (DIFEQ), showed inhibition of the adenosine…”
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4-Caffeoyl-1,5-quinide in roasted coffee inhibits [3H]naloxone binding and reverses anti-nociceptive effects of morphine in mice by DE PAULIS, Tomas, COMMERS, Patricia, FARAH, Adriana, JIALI ZHAO, MCDONALD, Michael P, GALICI, Ruggero, MARTIN, Peter R

“…Cinnamoylquinides are formed from the corresponding chlorogenic acids during coffee roasting. Instant coffee has been shown to displace binding of the mu…”
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Labeling of (S)-DES-4-amino-3-[125I]iodozacopride (DAIZAC), a high-affinity radioligand for the 5-HT-3 receptor by Mason, N. Scott, Hewlett, William A., Ebert, Michael H., Schmidt, Dennis E., de Paulis, Tomas

“…We have prepared (S)‐5‐chloro‐3‐[125I]iodo‐2‐methoxy‐N‐(1‐azabicyclo[2.2.2]oct‐3‐yl)‐benzamide ([125I]DAIZAC, [125I]‐3) as a radioligand for characterization…”
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On the topology of the norepinephrine transport carrier in rat hypothalamus. The site of action of tricyclic uptake inhibitors by de Paulis, T, Kelder, D, Ross, S B

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M-100907 (Aventis) by de Paulis, T

“…M-100907 is a highly selective 5-HT2A antagonist that is being developed by Aventis Pharmaceuticals, formerly Hoechst Marion Roussel (HMR), for the potential…”
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Identification of extrastriatal dopamine D2 receptors in post mortem human brain with [125I]epidepride by Kessler, R M, Whetsell, W O, Ansari, M S, Votaw, J R, de Paulis, T, Clanton, J A, Schmidt, D E, Mason, N S, Manning, R G

“…The regional distribution of striatal and extrastriatal dopamine D2 receptors in human brain was studied in vitro with (S)-N-[(1-ethyl-2-…”
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Solid state conformations and antidopaminergic effects of remoxipride hydrochloride and a closely related salicylamide, FLA 797, in relation to dopamine receptor models by Högberg, T, Rämsby, S, de Paulis, T, Stensland, B, Csöregh, I, Wägner, A

“…The X-ray structures of two new 2,6-disubstituted benzamides, i.e., remoxipride hydrochloride monohydrate…”
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Anxiolytic-like effects of DAIZAC, a selective high-affinity 5-HT3 receptor antagonist, in the mouse elevated plus-maze by ZHANG, Zhang-Jin, SCHMIDT, Dennis E, DE PAULIS, Tomas, TRIVEDI, Bakula L, ONAIVI, Emmanuel S, EBERT, Michael H, HEWLETT, William A

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Pharmacological characterization of morphine-6-sulfate and codeine-6-sulfate by Zuckerman, Amy, Bolan, Elizabeth, de Paulis, Tomas, Schmidt, Dennis, Spector, Sydney, Pasternak, Gavril W.

“…Morphine-6-sulfate (M6S) and codeine-6-sulfate (C6S) are mu-selective opiates which have been isolated from brain. M6S is an effective analgesic, with a…”
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