Search Results - "DE MIGUEL, Maria P"
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Derivation of Limbal Stem Cells from Human Adult Mesenchymal Stem Cells for the Treatment of Limbal Stem Cell Deficiency
Published in International journal of molecular sciences (25-01-2023)“…Approximately 10 million individuals have blindness due to limbal stem cell (LSCs) deficiency, one of the most challenging problems in ophthalmology. To…”
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Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation
Published in Nature genetics (01-04-2002)“…In a wide variety of animal species, oocyte maturation is arrested temporarily at prophase of meiosis I (ref. 1). Resumption of meiosis requires activation of…”
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Pluripotent Stem Cells: Origin, Maintenance and Induction
Published in Stem cell reviews (01-12-2010)“…Pluripotency is defined as the potential of a cell to differentiate into cells of the three germ layers: endoderm, mesoderm and ectoderm. In vivo, the presence…”
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Cellular Therapy With Human Autologous Adipose-Derived Adult Stem Cells for Advanced Keratoconus
Published in Cornea (01-08-2017)“…The aim of this phase 1 study was to preliminarily evaluate the safety and efficacy of autologous adipose-derived adult stem cell (ADASC) implantation within…”
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Corneal Stroma Cell Density Evolution in Keratoconus Corneas Following the Implantation of Adipose Mesenchymal Stem Cells and Corneal Laminas: An In Vivo Confocal Microscopy Study
Published in Investigative ophthalmology & visual science (17-04-2020)“…To report the corneal stroma cell density evolution identified by in vivo corneal confocal microscopy in humans using injected autologous adipose-derived adult…”
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Corneal stroma regeneration: Preclinical studies
Published in Experimental eye research (01-01-2021)“…Corneal grafting is one of the most common and successful forms of human tissue transplantation in the world, but the need for corneal grafting is growing and…”
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Cornea and ocular surface treatment
Published in Current stem cell research & therapy (01-06-2010)“…In addition to being a protective shield, the cornea represents two thirds of the eye's refractive power. Corneal pathology can affect one or all of the…”
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Treatment of corneal endothelial damage in a rabbit model with a bioengineered graft using human decellularized corneal lamina and cultured human corneal endothelium
Published in PloS one (21-11-2019)“…We aimed to investigate the functionality of human decellularized stromal laminas seeded with cultured human corneal endothelial cells as a tissue engineered…”
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Improvement of an Effective Protocol for Directed Differentiation of Human Adipose Tissue-Derived Adult Mesenchymal Stem Cells to Corneal Endothelial Cells
Published in International journal of molecular sciences (05-11-2021)“…Corneal disease affects 12.5 million individuals worldwide, with 2 million new cases each year. The standard treatment consists of a corneal transplantation…”
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10
Monocytes inhibit NK activity via TGF-β in patients with obstructive sleep apnoea
Published in The European respiratory journal (01-06-2017)“…Obstructive sleep apnoea (OSA) is associated with cancer incidence and mortality. The contribution of the immune system appears to be crucial; however, the…”
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Mesenchymal Stem Cells for Liver Regeneration in Liver Failure: From Experimental Models to Clinical Trials
Published in Stem cells international (01-01-2019)“…The liver centralizes the systemic metabolism and thus controls and modulates the functions of the central and peripheral nervous systems, the immune system,…”
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Adipose‐Derived Stem Cells Are a Source for Cell Therapy of the Corneal Stroma
Published in Stem cells (Dayton, Ohio) (01-02-2008)“…Most corneal diseases affect corneal stroma and include immune or infectious diseases, ecstatic disorders, traumatic scars, and corneal dystrophies. Cell‐based…”
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Adipose-derived mesenchymal stem cell administration does not improve corneal graft survival outcome
Published in PloS one (02-03-2015)“…The effect of local and systemic injections of mesenchymal stem cells derived from adipose tissue (AD-MSC) into rabbit models of corneal allograft rejection…”
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Corneal Stromal Regeneration: A Review of Human Clinical Studies in Keratoconus Treatment
Published in Frontiers in medicine (23-02-2021)“…The use of advanced therapies with stem cells to reconstruct the complex tissue of corneal stroma has gained interest in recent years. Besides, collagen-based…”
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Hypoxia Increases the Efficiencies of Cellular Reprogramming and Oncogenic Transformation in Human Blood Cell Subpopulations In Vitro and In Vivo
Published in Cells (Basel, Switzerland) (04-06-2024)“…Patients with chronic hypoxia show a higher tumor incidence; however, no primary common cause has been recognized. Given the similarities between cellular…”
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Regenerative Surgery of the Corneal Stroma for Advanced Keratoconus: 1-Year Outcomes
Published in American journal of ophthalmology (01-07-2019)“…This study evaluated 1-year safety and efficacy outcomes of corneal stroma cell therapy. Therapy consisted of implanting autologous adipose-derived adult stem…”
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Comparison of corneal haze and visual outcome in primary DSAEK versus DSAEK following failed DMEK
Published in Graefe's archive for clinical and experimental ophthalmology (01-11-2013)“…Background Descemet membrane endothelial keratoplasty (DMEK) is being proposed as the procedure of choice in corneal endothelial disease as it achieves better…”
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Corneal Stromal Regeneration Therapy for Advanced Keratoconus: Long-term Outcomes at 3 Years
Published in Cornea (01-06-2021)“…To report the 3-year clinical outcomes of corneal stromal cell therapy consisting of the intrastromal implantation with autologous adipose-derived adult stem…”
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Epiblast-derived stem cells in embryonic and adult tissues
Published in The International journal of developmental biology (2009)“…Pluripotent cells can be isolated from the mammalian inner cell mass (ICM) of the embryo at the blastocyst stage, and maintained in culture as…”
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Autoantibodies Against Perilipin 1 as a Cause of Acquired Generalized Lipodystrophy
Published in Frontiers in immunology (19-09-2018)“…Acquired generalized lipodystrophy (AGL) is a rare condition characterized by an altered distribution of adipose tissue and predisposition to develop hepatic…”
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