Search Results - "DE LUCA, Michele"

Single-keratinocyte transcriptomic analyses identify different clonal types and proliferative potential mediated by FOXM1 in human epidermal stem cells by Enzo, Elena, Secone Seconetti, Alessia, Forcato, Mattia, Tenedini, Elena, Polito, Maria Pia, Sala, Irene, Carulli, Sonia, Contin, Roberta, Peano, Clelia, Tagliafico, Enrico, Bicciato, Silvio, Bondanza, Sergio, De Luca, Michele

“…Autologous epidermal cultures restore a functional epidermis on burned patients. Transgenic epidermal grafts do so also in genetic skin diseases such as…”
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Long-Term Stability and Safety of Transgenic Cultured Epidermal Stem Cells in Gene Therapy of Junctional Epidermolysis Bullosa by De Rosa, Laura, Carulli, Sonia, Cocchiarella, Fabienne, Quaglino, Daniela, Enzo, Elena, Franchini, Eleonora, Giannetti, Alberto, De Santis, Giorgio, Recchia, Alessandra, Pellegrini, Graziella, De Luca, Michele

“…We report a long-term follow-up (6.5 years) of a phase I/II clinical trial envisaging the use of autologous genetically modified cultured epidermal stem cells…”
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Gel Formulation of Nabumetone and a Newly Synthesized Analog: Microemulsion as a Photoprotective Topical Delivery System by Grande, Fedora, Ragno, Gaetano, Muzzalupo, Rita, Occhiuzzi, Maria Antonietta, Mazzotta, Elisabetta, Luca, Michele De, Garofalo, Antonio, Ioele, Giuseppina

“…Photostability studies were performed on topical formulations containing the anti-inflammatory drug Nabumetone and an analog newly synthesized in order to…”
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Light-sensitive drugs in topical formulations: stability indicating methods and photostabilization strategies by Ioele, Giuseppina, Tavano, Lorena, Luca, Michele De, Muzzalupo, Rita, Mancuso, Annalisa, Ragno, Gaetano

“…Photostability tests applied on commercial specialties for topical use have demonstrated a greater vulnerability of several drugs, due to greater exposure to…”
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Optimization of wavelength range and data interval in chemometric analysis of complex pharmaceutical mixtures by De Luca, Michele, Ioele, Giuseppina, Spatari, Claudia, Ragno, Gaetano

“…The performance of different chemometric approaches was evaluated in the spectrophotometric determination of pharmaceutical mixtures characterized by having…”
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Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration by Rama, Paolo, Matuska, Stanislav, Paganoni, Giorgio, Spinelli, Alessandra, De Luca, Michele, Pellegrini, Graziella

“…Corneal damage may become permanent if the supply of limbal stem cells is compromised. In this long-term follow-up study of 113 eyes treated with autologous…”
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Advances in Gene/Cell Therapy in Epidermolysis Bullosa by Murauer, Eva M., Koller, Ulrich, Pellegrini, Graziella, luca, Michele De, Bauer, Johann W.

“…In the past few years, substantial preclinical and experimental advances have been made in the treatment of the severe monogenic skin blistering disease…”
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Comparative Assessment of Cultures from Oral and Urethral Stem Cells for Urethral Regeneration by Corradini, Francesca, Zattoni, Michela, Barbagli, Guido, Bianchi, Giampaolo, Giovanardi, Michael, Serafini, Chiava, Genna, Vicenzo G, Ribbene, Anna, Balò, Sofia, Fidanza, Francesco, Lazzeri, Massimo, Luca, Michele De, Pellegrini, Graziella

“…Urethral reconstruction has received much attention in recent years, due to pathologies such as recurrence of urethral strictures after treatments. Various…”
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Regeneration of the entire human epidermis using transgenic stem cells by Hirsch, Tobias, Rothoeft, Tobias, Teig, Norbert, Bauer, Johann W., Pellegrini, Graziella, De Rosa, Laura, Scaglione, Davide, Reichelt, Julia, Klausegger, Alfred, Kneisz, Daniela, Romano, Oriana, Secone Seconetti, Alessia, Contin, Roberta, Enzo, Elena, Jurman, Irena, Carulli, Sonia, Jacobsen, Frank, Luecke, Thomas, Lehnhardt, Marcus, Fischer, Meike, Kueckelhaus, Maximilian, Quaglino, Daniela, Morgante, Michele, Bicciato, Silvio, Bondanza, Sergio, De Luca, Michele

“…Junctional epidermolysis bullosa (JEB) is a severe and often lethal genetic disease caused by mutations in genes encoding the basement membrane component…”
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Anticancer Drugs: Recent Strategies to Improve Stability Profile, Pharmacokinetic and Pharmacodynamic Properties by Ioele, Giuseppina, Chieffallo, Martina, Occhiuzzi, Maria Antonietta, De Luca, Michele, Garofalo, Antonio, Ragno, Gaetano, Grande, Fedora

“…In past decades, anticancer research has led to remarkable results despite many of the approved drugs still being characterized by high systemic toxicity…”
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Artificial Neural Network Combined with Principal Component Analysis for Resolution of Complex Pharmaceutical Formulations by Ioele, Giuseppina, Luca, Michele De, Dinç, Erdal, Oliverio, Filomena, Ragno, Gaetano

“…A chemometric approach based on the combined use of the principal component analysis (PCA) and artificial neural network (ANN) was developed for the…”
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Eyes on the Prize: Limbal Stem Cells and Corneal Restoration by Pellegrini, Graziella, De Luca, Michele

“…Corneal diseases and blindness can result from deficiency in limbal stem cells, and autologous transplantation is often the only therapeutic option. Two recent…”
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1,4-Dihydropyridine Antihypertensive Drugs: Recent Advances in Photostabilization Strategies by De Luca, Michele, Ioele, Giuseppina, Ragno, Gaetano

“…The 1,4-dihydropyridine (DHP) drugs are nowadays the most used drugs in the treatment of hypertension. However, all the structures in this series present a…”
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Gentamicin induces LAMB3 nonsense mutation readthrough and restores functional laminin 332 in junctional epidermolysis bullosa by Lincoln, Vadim, Cogan, Jon, Hou, Yingping, Hirsch, Michaela, Hao, Michelle, Alexeev, Vitali, De Luca, Michele, De Rosa, Laura, Bauer, Johann W., Woodley, David T., Chen, Mei

“…Herlitz junctional epidermolysis bullosa (H-JEB) is an incurable, devastating, and mostly fatal inherited skin disease for which there is only supportive care…”
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Marketing of unproven stem cell-based interventions: A call to action by Sipp, Douglas, Caulfield, Timothy, Kaye, Jane, Barfoot, Jan, Blackburn, Clare, Chan, Sarah, De Luca, Michele, Kent, Alastair, McCabe, Christopher, Munsie, Megan, Sleeboom-Faulkner, Margaret, Sugarman, Jeremy, van Zimmeren, Esther, Zarzeczny, Amy, Rasko, John E J

“…Commercial promotion of unsupported therapeutic uses of stem cells is a global problem that has proven resistant to regulatory efforts. Here, we suggest a…”
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Editorial: Gene, Cell and Protein Replacement Therapy for Genetic Muscle, Bone and Skin Disorders by Schneider, Holm, De Luca, Michele

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Navigating Market Authorization: The Path Holoclar Took to Become the First Stem Cell Product Approved in the European Union by Pellegrini, Graziella, Ardigò, Diego, Milazzo, Giovanni, Iotti, Giorgio, Guatelli, Paolo, Pelosi, Danilo, De Luca, Michele

“…Gene therapy, cell therapy, and tissue engineering have the potential to revolutionize the treatment of disease and injury. Attaining marketing authorization…”
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Photodegradation of Anti-Inflammatory Drugs: Stability Tests and Lipid Nanocarriers for Their Photoprotection by Ioele, Giuseppina, Grande, Fedora, De Luca, Michele, Occhiuzzi, Maria Antonietta, Garofalo, Antonio, Ragno, Gaetano

“…The present paper provides an updated overview of the methodologies applied in photodegradation studies of non-steroidal anti-inflammatory drugs…”
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Multivariate curve resolution of incomplete fused multiset data from chromatographic and spectrophotometric analyses for drug photostability studies by Luca, Michele De, Ragno, Gaetano, Ioele, Giuseppina, Tauler, Romà

“…[Display omitted] •A new MCR-ALS algorithm is proposed for the analysis of incomplete fused multiset.•Resolution of the data allowed the description of…”
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Biochemical role of FOXM1-dependent histone linker H1B in human epidermal stem cells by Polito, Maria Pia, Marini, Grazia, Fabrizi, Alessandra, Sercia, Laura, Enzo, Elena, De Luca, Michele

“…Epidermal stem cells orchestrate epidermal renewal and timely wound repair through a tight regulation of self-renewal, proliferation, and differentiation. In…”
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