Search Results - "DE LONGUEVILLE, Francoise"

Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes by GILLET, Jean-Pierre, EFFERTH, Thomas, STEINBACH, Daniel, HAMELS, Jacques, DE LONGUEVILLE, Francoise, BERTHOLET, Vincent, REMACLE, José

“…Different mechanisms of drug resistance, including ATP-binding cassette (ABC) transporters, are responsible for treatment failure of tumors. We developed a…”
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Performance comparison of one-color and two-color platforms within the Microarray Quality Control (MAQC) project by Patterson, Tucker A, Lobenhofer, Edward K, Fulmer-Smentek, Stephanie B, Collins, Patrick J, Chu, Tzu-Ming, Bao, Wenjun, Fang, Hong, Kawasaki, Ernest S, Hager, Janet, Tikhonova, Irina R, Walker, Stephen J, Zhang, Liang, Hurban, Patrick, de Longueville, Francoise, Fuscoe, James C, Tong, Weida, Shi, Leming, Wolfinger, Russell D

“…Microarray-based expression profiling experiments typically use either a one-color or a two-color design to measure mRNA abundance. The validity of each…”
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ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia by STEINBACH, Daniel, GILLET, Jean-Pierre, SAUERBREY, Axel, GRUHN, Bernd, DAWCZYNSKI, Kristin, BERTHOLET, Vincent, DE LONGUEVILLE, Francoise, ZINTL, Felix, REMADE, Jose, EFFERTH, Thomas

“…Background: A major issue in the treatment of acute myeloid leukemia (AML) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by…”
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Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-β1 signaling pathway by Debacq-Chainiaux, Florence, Borlon, Céline, Pascal, Thierry, Royer, Véronique, Eliaers, François, Ninane, Noëlle, Carrard, Géraldine, Friguet, Bertrand, de Longueville, Françoise, Boffe, Sophie, Remacle, José, Toussaint, Olivier

“…Premature senescence of human diploid fibroblasts (HDFs) can be induced by exposures to a variety of oxidative stress and DNA damaging agents. In this study we…”
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Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity by Sermeus, Audrey, Cosse, Jean-Philippe, Crespin, Marianne, Mainfroid, Veronique, de Longueville, Francoise, Ninane, Noelle, Raes, Martine, Remacle, Jose, Michiels, Carine

“…it is now well established that hypoxia renders tumor cells resistant to radio- but also chemotherapy. However, few elements are currently available as for the…”
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CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes by Vankoningsloo, Sébastien, Pauw, Aurélia De, Houbion, Andrée, Tejerina, Silvia, Demazy, Catherine, Longueville, Françoise de, Bertholet, Vincent, Renard, Patricia, Remacle, José, Holvoet, Paul, Raes, Martine, Arnould, Thierry

“…Several mitochondrial pathologies are characterized by lipid redistribution and microvesicular cell phenotypes resulting from triglyceride accumulation in…”
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Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia by Efferth, Thomas, Gillet, Jean-Pierre, Sauerbrey, Axel, Zintl, Felix, Bertholet, Vincent, de Longueville, Françoise, Remacle, Jose, Steinbach, Daniel

“…A major issue in the treatment of T-cell acute lymphoblastic leukemia (T-ALL) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by…”
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Mild mitochondrial uncoupling induces 3T3-L1 adipocyte de-differentiation by a PPARγ-independent mechanism, whereas TNFα-induced de-differentiation is PPARγ dependent by Tejerina, Silvia, De Pauw, Aurélia, Vankoningsloo, Sébastien, Houbion, Andrée, Renard, Patricia, De Longueville, Françoise, Raes, Martine, Arnould, Thierry

“…Impairment of mitochondrial activity affects lipid-metabolizing tissues and mild mitochondrial uncoupling has been proposed as a possible strategy to fight…”
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Detection of disease resistance and susceptibility alleles in pigs using oligonucleotide microarray hybridization by Pastoret, Soumya, Ameels, Hélène, Bossiroy, Frédérique, Decreux, Annabelle, De Longueville, Françoise, Thomas, Anne, Desmecht, Daniel

“…A multiplex DNA microarray chip aimed at the identification of allelic polymorphisms was developed for simultaneous detection of swine disease resistance genes…”
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Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray by de Longueville, Françoise, Surry, Dominic, Meneses-Lorente, Georgina, Bertholet, Vincent, Talbot, Valérie, Evrard, Stephanie, Chandelier, Nathalie, Pike, Andrew, Worboys, Phil, Rasson, Jean-Paul, Le Bourdellès, Béatrice, Remacle, José

“…DNA microarrays are useful tools to study changes of gene expression in response to a treatment with drugs. Here, we describe the optimization of conditions…”
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Gene expression silencing with 'specific' small interfering RNA goes beyond specificity - a study of key parameters to take into account in the onset of small interfering RNA off-target effects by Vankoningsloo, Sébastien, de Longueville, Françoise, Evrard, Stéphanie, Rahier, Pierre, Houbion, Andrée, Fattaccioli, Antoine, Gastellier, Mélanie, Remacle, José, Raes, Martine, Renard, Patricia, Arnould, Thierry

“…RNA-mediated gene silencing (RNA interference) is a powerful way to knock down gene expression and has revolutionized the fields of cellular and molecular…”
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DualChip microarray as a new tool in cancer research by Gillet, Jean-Pierre, de Longueville, Françoise, Remacle, José

“…Over the last 5 years, the emergence of gene expression profiling using high-density DNA microarrays led to a better understanding of tumor development and…”
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Use of a Low-Density Microarray for Studying Gene Expression Patterns Induced by Hepatotoxicants on Primary Cultures of Rat Hepatocytes by de Longueville, Francoise, Atienzar, Franck A., Marcq, Laurence, Dufrane, Simon, Evrard, Stéphanie, Wouters, Lydia, Leroux, Florence, Bertholet, Vincent, Gerin, Brigitte, Whomsley, Rhys, Arnould, Thierry, Remacle, José, Canning, Mickael

“…In the field of gene expression analysis, DNA microarray technology is having a major impact on many different areas including toxicology. For instance, a…”
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ABCChips as New Diagnostic Tool to Monitoring Multidrug Resistance in Human Tumor Cells to Chemotherapeutics Agents by Expression Profiling of ATP-Binding Cassette Transporter Genes by Gillet, Jean-Pierre, Efferth, Thomas, Steinbach, Damiel, de Longueville, Françoise, Bertholet, Vincent, Remacle, José, Sayer, Herbert G.

“…A major problem in the treatment of tumors represents the development of resistance to chemotherapy. Many mechanisms are responsible for the failure of…”
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An Evaluation of a Low-Density DNA Microarray Using Cytochrome P450 Inducers by Meneses-Lorente, Georgina, de Longueville, Françoise, Dos Santos-Mendes, Sofia, Bonnert, Timothy P, Jack, Andrew, Evrard, Stéphanie, Bertholet, Vincent, Pike, Andrew, Scott-Stevens, Paul, Remacle, José, Sohal, Bindi

“…The aim of this study was to validate a low-density DNA microarray “Rat HepatoChip”, which contains 59 genes from a range of potential toxic markers and drug…”
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New chips for molecular biology and diagnostics by Zammatteo, Nathalie, Hamels, Sandrine, De Longueville, Françoise, Alexandre, Isabelle, Gala, Jean-luc, Brasseur, Francis, Remacle, José

“…The DNA chips are arrays of DNA probes immobilized on solid support for simultaneous identification of many target DNA sequences. DNA chips applied to…”
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Molecular characterization of breast cancer cell lines by a low-density microarray by de Longueville, Francoise, Lacroix, Marc, Barbuto, Anna-Maria, Bertholet, Vincent, Gallo, Dominique, Larsimont, Denis, Marcq, Laurence, Zammatteo, Nathalie, Boffe, Sophie, Leclercq, Guy, Remacle, Jose

“…We designed a low-density microarray carrying 132 DNA capture sequences highly specific for genes known to be differentially expressed among breast tumors and…”
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Expression Profiling of ABC-Transporters in Childhood AML Reveals ABCA3 as a Potential Cause of Drug Resistance by Steinbach, Daniel, Gillet, Jean-Pierre, Sauerbrey, Axel, Gruhn, Bernd, Dawczynski, Kristin, de Longueville, Francoise, Bertholet, Vincent, Zintl, Felix, Remacle, Jose, Efferth, Thomas

“…A major issue in the treatment of acute myeloid leukemia (AML) is the development of resistance to chemotherapeutic drugs. While more than 80% of children with…”
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Mild mitochondrial uncoupling induces 3T3-L1 adipocyte de-differentiation by a PPARgamma-independent mechanism, whereas TNFalpha-induced de-differentiation is PPARgamma dependent by Tejerina, Silvia, De Pauw, Aurélia, Vankoningsloo, Sébastien, Houbion, Andrée, Renard, Patricia, De Longueville, Françoise, Raes, Martine, Arnould, Thierry

“…Impairment of mitochondrial activity affects lipid-metabolizing tissues and mild mitochondrial uncoupling has been proposed as a possible strategy to fight…”
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Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase by de Magalhães, João Pedro, Chainiaux, Florence, de Longueville, Françoise, Mainfroid, Véronique, Migeot, Valérie, Marcq, Laurence, Remacle, José, Salmon, Michel, Toussaint, Olivier

“…We compared the DNA-binding activity of transcription factors and gene expression patterns in BJ human diploid fibroblasts (HDFs) expressing or not telomerase…”
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