Search Results - "DE LEON, J"

Microglial activation and tau propagate jointly across Braak stages by Pascoal, Tharick A., Benedet, Andrea L., Ashton, Nicholas J., Kang, Min Su, Therriault, Joseph, Chamoun, Mira, Savard, Melissa, Lussier, Firoza Z., Tissot, Cécile, Karikari, Thomas K., Ottoy, Julie, Mathotaarachchi, Sulantha, Stevenson, Jenna, Massarweh, Gassan, Schöll, Michael, de Leon, Mony J., Soucy, Jean-Paul, Edison, Paul, Blennow, Kaj, Zetterberg, Henrik, Gauthier, Serge, Rosa-Neto, Pedro

“…Compelling experimental evidence suggests that microglial activation is involved in the spread of tau tangles over the neocortex in Alzheimer’s disease (AD)…”
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Pharmacogenetics and pharmacogenomics of schizophrenia: a review of last decade of research by ARRANZ, M. J, DE LEON, J

“…The last decade of research into the pharmacogenetics of antipsychotics has seen the development of genetic tests to determine the patients' metabolic status…”
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Traumatic Brain Injury and Alzheimer's Disease: The Cerebrovascular Link by Ramos-Cejudo, Jaime, Wisniewski, Thomas, Marmar, Charles, Zetterberg, Henrik, Blennow, Kaj, de Leon, Mony J., Fossati, Silvia

“…Traumatic brain injury (TBI) and Alzheimer's disease (AD) are devastating neurological disorders, whose complex relationship is not completely understood…”
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Is "memory-for-when" universal? Group and individual variability in temporal position memory for words, faces, and classrooms by Delaney, Peter F., de Leon Guerrero, Agustin J., Cook, Myranda, Jones, Todd C.

“…Many contemporary theories of memory assume that everyone automatically stores temporal contextual information about all types of encountered information, yet…”
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Antipsychotic medication exposure, clozapine, and pneumonia: results from a self‐controlled study by Rohde, C., Siskind, D., Leon, J., Nielsen, J.

“…Objective By using a self‐controlled design, we investigated whether antipsychotic medication exposure was associated with increased pneumonia risk and whether…”
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The queen conch mitogenome: intra- and interspecific mitogenomic variability in Strombidae and phylogenetic considerations within the Hypsogastropoda by Machkour-M’Rabet, Salima, Hanes, Margaret M., Martínez-Noguez, Josué Jacob, Cruz-Medina, Jorge, García-De León, Francisco J.

“…Aliger gigas is an economically important and vulnerable marine species. We present a new mitogenome of A. gigas from the Mexican Caribbean and use the eight…”
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TOI 4201 b and TOI 5344 b: Discovery of Two Transiting Giant Planets around M-dwarf Stars and Revised Parameters for Three Others by Hartman, J. D., Bakos, G. Á., Csubry, Z., Howard, A. W., Isaacson, H., Giacalone, S., Chontos, A., Narita, N., Fukui, A., de Leon, J. P., Watanabe, N., Mori, M., Kagetani, T., Fukuda, I., Kawai, Y., Ikoma, M., Palle, E., Murgas, F., Esparza-Borges, E., Parviainen, H., Bouma, L. G., Cointepas, M., Bonfils, X., Almenara, J. M., Collins, Karen A., Collins, Kevin I., Relles, Howard M., Barkaoui, Khalid, Schwarz, Richard P., Mourad, Ghachoui, Timmermans, Mathilde, Dransfield, Georgina, Burdanov, Artem, de Wit, Julien, Jehin, Emmanuël, Triaud, Amaury H. M. J., Gillon, Michaël, Benkhaldoun, Zouhair, Horne, Keith, Sefako, Ramotholo, Jordán, A., Brahm, R., Suc, V., Howell, Steve B., Furlan, E., Schlieder, J. E., Ciardi, D., Barclay, T., Gonzales, E. J., Crossfield, I., Dressing, C. D., Goliguzova, M., Tatarnikov, A., Ricker, George R., Vanderspek, Roland, Latham, David W., Seager, S., Winn, Joshua N., Jenkins, Jon M., Striegel, Stephanie, Shporer, Avi, Vanderburg, Andrew, Levine, Alan M., Kostov, Veselin B., Watanabe, David

“…Abstract We present the discovery from the TESS mission of two giant planets transiting M-dwarf stars: TOI 4201 b and TOI 5344 b. We also provide precise…”
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The nonlinear relationship between cerebrospinal fluid Aβ42 and tau in preclinical Alzheimer's disease by de Leon, Mony J, Pirraglia, Elizabeth, Osorio, Ricardo S, Glodzik, Lidia, Saint-Louis, Les, Kim, Hee-Jin, Fortea, Juan, Fossati, Silvia, Laska, Eugene, Siegel, Carole, Butler, Tracy, Li, Yi, Rusinek, Henry, Zetterberg, Henrik, Blennow, Kaj

“…Cerebrospinal fluid (CSF) studies consistently show that CSF levels of amyloid-beta 1-42 (Aβ42) are reduced and tau levels increased prior to the onset of…”
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Ballooning of the levator hiatus by Dietz, H. P., Shek, C., De Leon, J., Steensma, A. B.

“…Objective The levator hiatus defines the ‘hernial portal’ through which female pelvic organ prolapse develops. Hiatal area may therefore be an independent…”
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Plasma tau complements CSF tau and P-tau in the diagnosis of Alzheimer's disease by Fossati, Silvia, Ramos Cejudo, Jaime, Debure, Ludovic, Pirraglia, Elizabeth, Sone, Je Yeong, Li, Yi, Chen, Jingyun, Butler, Tracy, Zetterberg, Henrik, Blennow, Kaj, de Leon, Mony J.

“…Plasma tau may be an accessible biomarker for Alzheimer's disease (AD), but the correlation between plasma and cerebrospinal fluid (CSF) tau and the value of…”
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Evaluation of extraction methods for preparative scale obtention of mangiferin and lupeol from mango peels (Mangifera indica L.) by Ruiz-Montañez, G., Ragazzo-Sánchez, J.A., Calderón-Santoyo, M., Velázquez-de la Cruz, G., Ramírez de León, J.A., Navarro-Ocaña, A.

“…•Mango peels are an important source of mangiferin and lupeol.•Mangiferin and lupeol contents were higher in mango at consumption maturity stage.•The…”
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Loss of the tumor suppressor spinophilin (PPP1R9B) increases the cancer stem cell population in breast tumors by Ferrer, I, Verdugo-Sivianes, E M, Castilla, M A, Melendez, R, Marin, J J, Muñoz-Galvan, S, Lopez-Guerra, J L, Vieites, B, Ortiz-Gordillo, M J, De León, J M, Praena-Fernandez, J M, Perez, M, Palacios, J, Carnero, A

“…The spinophilin (Spn, PPP1R9B) gene is located at 17q21.33, a region frequently associated with microsatellite instability and loss of heterozygosity,…”
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Genetic diversity and structure of circumtropical almaco jack, Seriola rivoliana: tool for conservation and management by Mendoza‐Portillo, Verónica, Galván‐Tirado, Carolina, Portnoy, David S., Valenzuela‐Quiñonez, Fausto, Domínguez‐Domínguez, Omar, Durand, Jean‐Dominique, Pérez‐Urbiola, Juan Carlos, García‐De León, Francisco J.

“…The almaco jack, Seriola rivoliana, is a circumtropical pelagic fish of importance both in commercial fisheries and in aquaculture. To understand levels of…”
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Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease by MOSCONI, L, MISTUR, R, SWITALSKI, R, BRYS, M, GLODZIK, L, RICH, K, PIRRAGLIA, E, TSUI, W, DE SANTI, S, DE LEON, M. J

“…At cross-section, cognitively normal individuals (NL) with a maternal history of late-onset Alzheimer disease (AD) have reduced glucose metabolism (CMRglc) on…”
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Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease by Mosconi, Lisa, Pupi, Alberto, De Leon, Mony J.

“…One of the main features of Alzheimer's disease (AD) is the severe reduction of the cerebral metabolic rate for glucose (CMRglc). In vivo imaging using…”
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Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism by Mosconi, Lisa, Brys, Miroslaw, Switalski, Remigiusz, Mistur, Rachel, Glodzik, Lidia, Pirraglia, Elizabeth, Tsui, Wai, De Santi, Susan, de Leon, Mony J

“…Having a parent affected with late-onset Alzheimer's disease (AD) is a risk factor for developing AD among cognitively normal subjects. We examined whether…”
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Viral Suppression Levels in Men Who Have Sex With Men and Transgender Women With Newly Diagnosed HIV and Alcohol Use Disorder in Peru: Results From a Randomized, Double-Blind, Placebo-Controlled Trial Using Oral Naltrexone by Gonzales, Pedro, Bachireddy, Chethan, Grieco, Arielle, Ding, Rona, Galvez de Leon, Samy J., Ulrich, Angela, Lama, Javier, Duerr, Ann C, Altice, Frederick L.

“…Alcohol use disorders (AUDs) are common in men who have sex with men (MSM) and transgender women (TGW) in Peru and undermine antiretroviral therapy (ART)…”
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Paying attention to pharmacokinetic and pharmacodynamic mechanisms to progress in the area of anticholinergic use in geriatric patients by de Leon, J

“…Many naturalistic studies agree that adverse drug reactions (ADRs), particularly cognitive deficits, frequently occur when medications with anticholinergic…”
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Periodontal disease as a possible cause for Alzheimer's disease by Kamer, Angela R., Craig, Ronald G., Niederman, Richard, Fortea, Juan, de Leon, Mony J.

“…Approximately 47 million people worldwide have been diagnosed with dementia, 60%‐80% of whom have dementia of the Alzheimer’s disease type. Unfortunately,…”
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A deep sequencing approach to uncover the miRNOME in the human heart by Leptidis, Stefanos, El Azzouzi, Hamid, Lok, Sjoukje I, de Weger, Roel, Olieslagers, Servé, Olieslagers, Serv, Kisters, Natasja, Silva, Gustavo J, Heymans, Stephane, Cuppen, Edwin, Berezikov, Eugene, De Windt, Leon J, da Costa Martins, Paula

“…MicroRNAs (miRNAs) are a class of non-coding RNAs of ∼22 nucleotides in length, and constitute a novel class of gene regulators by imperfect base-pairing to…”
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