Search Results - "DE LENCASTRE, HERMINIA"

Dynamics of Pneumococcal Carriage in Adults: A New Look at an Old Paradigm by Almeida, Sónia T, Paulo, Ana Cristina, Froes, Filipe, de Lencastre, Hermínia, Sá-Leão, Raquel

“…Abstract Background Limited information is available on pneumococcal colonization among adults. We studied pneumococcal carriage dynamics in healthy adults…”
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Genomic analysis of Enterococcus faecium from non-clinical settings: antimicrobial resistance, virulence, and clonal population in livestock and the urban environment by Lopes, Jéssica, de Lencastre, Hermínia, Conceição, Teresa

“…Enterococci are commensals of the gastrointestinal tract of humans and animals that evolved into opportunistic pathogens with high antimicrobial resistance and…”
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Impact of Insertion Sequences and Recombination on the Population Structure of Staphylococcus haemolyticus by Bouchami, Ons, de Lencastre, Herminia, Miragaia, Maria

“…Staphylococcus haemolyticus is one of the most common pathogens associated with medical-device related infections, but its molecular epidemiology is poorly…”
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Epidemiology and antimicrobial resistance of methicillin-resistant Staphylococcus aureus isolates colonizing pigs with different exposure to antibiotics by Lopes, Elizeth, Conceição, Teresa, Poirel, Laurent, de Lencastre, Hermínia, Aires-de-Sousa, Marta

“…In 2016, very high rates of methicillin-resistant Staphylococcus aureus (MRSA)-ST398 (99%) were found in Portuguese pig farms that used colistin, amoxicillin,…”
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Carriage of Staphylococcus aureus among Portuguese nursing students: A longitudinal cohort study over four years of education by Conceição, Teresa, de Lencastre, Hermínia, Aires-de-Sousa, Marta

“…Staphylococcus aureus is a major human pathogen that can colonize healthy people mainly in the anterior nares. The aim of the present study was to evaluate S…”
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Phenotypic signatures and genetic determinants of oxacillin tolerance in a laboratory mutant of Staphylococcus aureus by Chung, Marilyn, Borges, Vitor, Gomes, João Paulo, de Lencastre, Herminia, Tomasz, Alexander

“…Addition of β-lactam antibiotics to growing cultures of bacteria inhibit synthesis of the bacterial cell wall peptidoglycan accompanied by killing (loss of…”
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Methicillin-resistance in Staphylococcus aureus is not affected by the overexpression in trans of the mecA gene repressor: a surprising observation by Oliveira, Duarte C, de Lencastre, Hermínia

“…Methicillin-resistant Staphylococcus aureus (MRSA) is intrinsically cross-resistant to virtually all β-lactam antibiotics. The central determinant for the MRSA…”
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Prevalence of biocide resistance genes and chlorhexidine and mupirocin non-susceptibility in Portuguese hospitals during a 31-year period (1985–2016) by Conceição, Teresa, de Lencastre, Hermínia, Aires-de-Sousa, Marta

“…•High prevalence of biocide resistance genes among MRSA in Portuguese hospitals.•Significant mupirocin non-susceptibility (15.4%) associated with the EMRSA-15…”
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Absence of methicillin-resistant Staphylococcus aureus colonization among immunocompetent healthy adults: Insights from a longitudinal study by Almeida, Sónia T, Paulo, A. Cristina, Babo, João, Borralho, João, Figueiredo, Catarina, Gonçalves, Bruno, Lança, João, Louro, Mónica, Morais, Hermes, Queiroz, Joana, de Lencastre, Hermínia, Sá-Leão, Raquel

“…Methicillin-resistant Staphylococcus aureus (MRSA) has long been known as a major cause of hospital-acquired (HA-MRSA) infections worldwide. For the past…”
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Multiplex Real-Time PCR for Rapid Staphylococcal Cassette Chromosome mec Typing by Chen, Liang, Mediavilla, José R, Oliveira, Duarte C, Willey, Barbara M, de Lencastre, Herminia, Kreiswirth, Barry N

“…Rapid identification and typing of methicillin (meticillin)-resistant Staphylococcus aureus (MRSA) is important for understanding the molecular epidemiology…”
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Impact of the Stringent Stress Response on the Expression of Methicillin Resistance in Staphylococcaceae Strains Carrying mecA , mecA1 and mecC by Milheiriço, Catarina, Tomasz, Alexander, de Lencastre, Hermínia

“…The acquisition of the resistance determinant by is of major clinical importance, since it confers a resistant phenotype to virtually the entire large family…”
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The anti-repressor MecR2 promotes the proteolysis of the mecA repressor and enables optimal expression of β-lactam resistance in MRSA by Arêde, Pedro, Milheiriço, Catarina, de Lencastre, Hermínia, Oliveira, Duarte C

“…Methicillin-resistant Staphylococcus aureus (MRSA) is an important human pathogen, which is cross-resistant to virtually all β-lactam antibiotics. MRSA strains…”
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The blp Locus of Streptococcus pneumoniae Plays a Limited Role in the Selection of Strains That Can Cocolonize the Human Nasopharynx by Valente, Carina, Dawid, Suzanne, Pinto, Francisco R, Hinds, Jason, Simões, Alexandra S, Gould, Katherine A, Mendes, Luís A, de Lencastre, Hermínia, Sá-Leão, Raquel

“…Nasopharyngeal colonization is important for Streptococcus pneumoniae evolution, providing the opportunity for horizontal gene transfer when multiple strains…”
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Evidence for the dissemination to humans of Methicillin-Resistant Staphylococcus aureus ST398 through the pork production chain : a study in a portuguese slaughterhouse by Bouchami, Ons, Fraqueza, Maria João, Faria, Nuno Alexandre, Alves, Valquíria, Lawal, Opeyemi Uwangbaoje, Lencastre, Herminia de, Miragaia, Maria

“…Research Areas: Microbiology Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) ST398 was recovered from infections in humans exposed…”
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Complementation of the Essential Peptidoglycan Transpeptidase Function of Penicillin-Binding Protein 2 (PBP2) by the Drug Resistance Protein PBP2A in Staphylococcus aureus by Pinho, M G, Filipe, S R, de Lencastre, H, Tomasz, A

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Epidemiology and population structure of serotypes 1, 5 and 7f carried by children in Portugal from 1996-2010 before introduction of the 10-valent and 13-valent pneumococcal conjugate vaccines by Almeida, Sónia T, de Lencastre, Hermínia, Sá-Leão, Raquel

“…Among the over 90 serotypes of Streptococcus pneumoniae described, serotypes 1, 5, and 7F account for a significant proportion of invasive disease worldwide…”
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Identification of Clinical Staphylococcal Isolates from Humans by Internal Transcribed Spacer PCR by COUTO, Isabel, PEREIRA, Sandro, MIRAGAIA, Maria, SANCHES, Ilda Santos, DE LENCASTRE, Herminia

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Methicillin-resistant Staphylococcus aureus by Lee, Andie S., de Lencastre, Hermínia, Garau, Javier, Kluytmans, Jan, Malhotra-Kumar, Surbhi, Peschel, Andreas, Harbarth, Stephan

“…Since the 1960s, methicillin-resistant Staphylococcus aureus (MRSA) has emerged, disseminated globally and become a leading cause of bacterial infections in…”
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Methicillin-resistant Staphylococcus aureus emerged long before the introduction of methicillin into clinical practice by Harkins, Catriona P, Pichon, Bruno, Doumith, Michel, Parkhill, Julian, Westh, Henrik, Tomasz, Alexander, de Lencastre, Herminia, Bentley, Stephen D, Kearns, Angela M, Holden, Matthew T G

“…The spread of drug-resistant bacterial pathogens poses a major threat to global health. It is widely recognised that the widespread use of antibiotics has…”
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Antibiotic resistant Staphylococcus aureus : a paradigm of adaptive power by de Lencastre, Herminia, Oliveira, Duarte, Tomasz, Alexander

“…Nothing documents better the spectacular adaptive capacity of Staphylococcus aureus than the response of this important human and animal pathogen to the…”
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