Search Results - "DE LEEUW, Hubert"

POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors by LOOIJENGA, Leendert H. J, STOOP, Hans, HONECKER, Friedemann, BOKEMEYER, Carsten, PERLMAN, Elizabeth J, SCHNEIDER, Dominik T, KONONEN, Juha, SAUTER, Guido, OOSTERHUIS, J. Wolter, DE LEEUW, Hubert P. J. C, DE GOUVEIA BRAZAO, Carlos A, GILLIS, Ad J. M, VAN ROOZENDAAL, Kees E. P, VAN ZOELEN, Everardus J. J, WEBER, Rob F. A, WOLFFENBUTTEL, Katja P, VAN DEKKEN, Herman

“…Human germ cell tumors (GCTs) may have variable histology and clinical behavior, depending on factors such as sex of the patient, age at clinical diagnosis,…”
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Small GTP-Binding Protein Ral Modulates Regulated Exocytosis of von Willebrand Factor by Endothelial Cells by de Leeuw, Hubert P.J.C, Fernandez-Borja, Mar, Reits, Eric A.J, de Wit, Thalia Romani, Wijers-Koster, Pauline M, Hordijk, Peter L, Neefjes, Jacques, van Mourik, Jan A, Voorberg, Jan

“…ABSTRACT—Weibel-Palade bodies are endothelial cell–specific organelles, which contain von Willebrand factor (vWF), P-selectin, and several other proteins…”
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Von Willebrand factor targets IL-8 to Weibel–Palade bodies in an endothelial cell line by Romani de Wit, Thalia, de Leeuw, Hubert P.J.C, Rondaij, Mariska G, de Laaf, Rozalia T.M, Sellink, Erica, Brinkman, Herm-Jan, Voorberg, Jan, van Mourik, Jan A

“…Vascular endothelial cells are able to store the chemotactic cytokine interleukin-8 (IL-8) in specialized storage vesicles, Weibel–Palade bodies, together with…”
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Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms by Echard, A, Opdam, F J, de Leeuw, H J, Jollivet, F, Savelkoul, P, Hendriks, W, Voorberg, J, Goud, B, Fransen, J A

“…Analysis of the human Rab6A gene structure reveals the presence of a duplicated exon, and incorporation of either of the two exons by alternative splicing is…”
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Small GTP-binding protein RalA associates with Weibel-Palade bodies in endothelial cells by de Leeuw, H P, Wijers-Koster, P M, van Mourik, J A, Voorberg, J

“…In endothelial cells von Willebrand factor (vWF) and P-selectin are stored in dense granules. so-called Weibel-Palade bodies. Upon stimulation of endothelial…”
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Small GTP‐binding proteins in human endothelial cells by De Leeuw, Hubert P. J. C., Koster, Pauline M., Calafat, Jero, Janssen, Hans, Van Zonneveld, Anton‐Jan, Van Mourik, Jan A., Voorberg, Jan

“…Small GTP‐binding proteins of the Ras superfamily control an extensive number of intracellular events by alternating between GDP‐ and GTP‐bound conformation…”
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Assembly of Multimeric von Willebrand Factor Directs Sorting of P-Selectin by Hop, Caroline, Guilliatt, Andrea, Daly, Martina, de Leeuw, Hubert P, Brinkman, Herm-Jan M, Peake, Ian R, van Mourik, Jan A, Pannekoek, Hans

“…We designed a model system to study the role of von Willebrand factor (vWF) in the sorting of P-selectin and the biogenesis of Weibel-Palade body (WPB)–like…”
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Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ-cell tumors by LOOIJENGA, Leendert H. J, DE LEEUW, Hubert, VON LINDERN, Marieke, VALK, Peter, LAJOS, Geczy, OLAH, Edit, NESLAND, Jahn M, FOSSA, Sophie D, OOSTERHUIS, J. Wolter, VAN OORSCHOT, Monique, VAN GURP, Ruud J. H. L. M, STOOP, Hans, GILLIS, Ad J. M, DE GOUVEIA BRAZAO, Carlos A, WEBER, Rob F. A, KIRKELS, Wim J, VAN DIJK, Thamar

“…Testicular germ-cell tumors (TGCTs) of adolescents and adults originate from intratubular germ cell neoplasia (ITGCN), which is composed of the malignant…”
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