Search Results - "DE LANGE, Pieter"

Differential Effects of 3,5-Diiodo-L-Thyronine and 3,5,3’-Triiodo-L-Thyronine On Mitochondrial Respiratory Pathways in Liver from Hypothyroid Rats by Silvestri, Elena, Lombardi, Assunta, Coppola, Maria, Gentile, Alessandra, Cioffi, Federica, Senese, Rosalba, Goglia, Fernando, Lanni, Antonia, Moreno, Maria, de Lange, Pieter

“…Background/Aims: Both 3,5-diiodo-L-thyronine (3,5-T2) and 3,5,3’-triiodo-L-tyronine (T3) affect energy metabolism having mitochondria as a major target…”
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(Healthy) ageing: focus on iodothyronines by de Lange, Pieter, Cioffi, Federica, Silvestri, Elena, Moreno, Maria, Goglia, Fernando, Lanni, Antonia

“…The activity of the thyroid gland diminishes during ageing, but a certain tissue reserve of T3 and its metabolites is maintained. This reserve is thought to…”
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Editorial: A year in review: discussions in cellular endocrinology by Romero, Damian G, de Lange, Pieter

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Adipose Tissue Remodeling in Obesity: An Overview of the Actions of Thyroid Hormones and Their Derivatives by Petito, Giuseppe, Cioffi, Federica, Magnacca, Nunzia, de Lange, Pieter, Senese, Rosalba, Lanni, Antonia

“…Metabolic syndrome and obesity have become important health issues of epidemic proportions and are often the cause of related pathologies such as type 2…”
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Editorial: Thyroid hormone and metabolites: central versus peripheral effects, volume II by de Lange, Pieter, Cioffi, Federica, Senese, Rosalba, Chiellini, Grazia

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3,5-Diiodothyronine: A Novel Thyroid Hormone Metabolite and Potent Modulator of Energy Metabolism by Senese, Rosalba, de Lange, Pieter, Petito, Giuseppe, Moreno, Maria, Goglia, Fernando, Lanni, Antonia

“…Over 30 years of research has demonstrated that 3,5-diiodo-L-thyronine (3,5-T2), an endogenous metabolite of thyroid hormones, exhibits interesting metabolic…”
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Physiological Approaches Targeting Cellular and Mitochondrial Pathways Underlying Adipose Organ Senescence by de Lange, Pieter, Lombardi, Assunta, Silvestri, Elena, Cioffi, Federica, Giacco, Antonia, Iervolino, Stefania, Petito, Giuseppe, Senese, Rosalba, Lanni, Antonia, Moreno, Maria

“…The adipose organ is involved in many metabolic functions, ranging from the production of endocrine factors to the regulation of thermogenic processes. Aging…”
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Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms by Pieter de Lange, Moreno, Maria, Silvestri, Elena, Lombardi, Assunta, Goglia, Fernando, Lanni, Antonia

“…Energy deprivation poses a tremendous challenge to skeletal muscle. Glucose (ATP) depletion causes muscle fibers to undergo rapid adaptive changes toward the…”
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Mild Endurance Exercise during Fasting Increases Gastrocnemius Muscle and Prefrontal Cortex Thyroid Hormone Levels through Differential BHB and BCAA-Mediated BDNF-mTOR Signaling in Rats by Giacco, Antonia, Cioffi, Federica, Cuomo, Arianna, Simiele, Roberta, Senese, Rosalba, Silvestri, Elena, Amoresano, Angela, Fontanarosa, Carolina, Petito, Giuseppe, Moreno, Maria, Lanni, Antonia, Lombardi, Assunta, de Lange, Pieter

“…Mild endurance exercise has been shown to compensate for declined muscle quality and may positively affect the brain under conditions of energy restriction…”
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Comparative effects of 3,5-diiodo-L-thyronine and 3,5,3'-triiodo-L-thyronine on mitochondrial damage and cGAS/STING-driven inflammation in liver of hypothyroid rats by Giacco, Antonia, Petito, Giuseppe, Silvestri, Elena, Scopigno, Nicla, Vigliotti, Michela, Mercurio, Giovanna, de Lange, Pieter, Lombardi, Assunta, Moreno, Maria, Goglia, Fernando, Lanni, Antonia, Senese, Rosalba, Cioffi, Federica

“…Maintaining a well-functioning mitochondrial network through the mitochondria quality control (MQC) mechanisms, including biogenesis, dynamics and mitophagy,…”
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Exercise Equals the Mobilization of Visceral versus Subcutaneous Adipose Fatty Acid Molecules in Fasted Rats Associated with the Modulation of the AMPK/ATGL/HSL Axis by Zotti, Tiziana, Giacco, Antonia, Cuomo, Arianna, Cerulo, Luigi, Petito, Giuseppe, Iervolino, Stefania, Senese, Rosalba, Cioffi, Federica, Vito, Pasquale, Cardinale, Gaetano, Silvestri, Elena, Lombardi, Assunta, Moreno, Maria, Lanni, Antonia, de Lange, Pieter

“…Combining exercise with fasting is known to boost fat mass-loss, but detailed analysis on the consequential mobilization of visceral and subcutaneous…”
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3,5-diiodo- l -thyronine, by modulating mitochondrial functions, reverses hepatic fat accumulation in rats fed a high-fat diet by Mollica, Maria Pina, Lionetti, Lillà, Moreno, Maria, Lombardi, Assunta, De Lange, Pieter, Antonelli, Alessandro, Lanni, Antonia, Cavaliere, Gina, Barletta, Antonio, Goglia, Fernando

“…Background/Aims Mitochondrial dysfunction is central to the physiopathology of steatosis and/or non-alcoholic fatty liver disease. In this study on rats we…”
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Exercise, fasting, and mimetics: toward beneficial combinations? by Jaspers, Richard T., Zillikens, M. Carola, Friesema, Edith C. H., Paoli, Giuseppe, Bloch, Wilhelm, Uitterlinden, André G., Goglia, Fernando, Lanni, Antonia, Lange, Pieter

“…Obesity and type 2 diabetes are associated disorders that involve a multiplicity of tissues. Both fasting and physical exercise are known to counteract…”
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3,5-Diiodo-L-Thyronine (T2) Administration Affects Visceral Adipose Tissue Inflammatory State in Rats Receiving Long-Lasting High-Fat Diet by Petito, Giuseppe, Cioffi, Federica, Silvestri, Elena, De Matteis, Rita, Lattanzi, Davide, de Lange, Pieter, Lombardi, Assunta, Moreno, Maria, Goglia, Fernando, Lanni, Antonia, Senese, Rosalba

“…3,5-diiodo-thyronine (T2), an endogenous metabolite of thyroid hormones, exerts beneficial metabolic effects. When administered to overweight rats receiving a…”
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New avenues for regulation of lipid metabolism by thyroid hormones and analogs by Senese, Rosalba, Lasala, Pasquale, Leanza, Cristina, de Lange, Pieter

“…Weight loss due to negative energy balance is a goal in counteracting obesity and type 2 diabetes mellitus. The thyroid is known to be an important regulator…”
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Editorial: Thyroid Hormone and Metabolites: Central Versus Peripheral Effects by Chiellini, Grazia, Cioffi, Federica, Senese, Rosalba, de Lange, Pieter

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Mild Exercise Rescues Steroidogenesis and Spermatogenesis in Rats Submitted to Food Withdrawal by Santillo, Alessandra, Giacco, Antonia, Falvo, Sara, Di Giacomo Russo, Federica, Senese, Rosalba, Di Fiore, Maria Maddalena, Chieffi Baccari, Gabriella, Lanni, Antonia, de Lange, Pieter

“…The present investigation was undertaken to increase our insight into the molecular basis of the physiological changes in rat testis induced by food…”
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Effect of CB1 Receptor Deficiency on Mitochondrial Quality Control Pathways in Gastrocnemius Muscle by Senese, Rosalba, Petito, Giuseppe, Silvestri, Elena, Ventriglia, Maria, Mosca, Nicola, Potenza, Nicoletta, Russo, Aniello, Manfrevola, Francesco, Cobellis, Gilda, Chioccarelli, Teresa, Porreca, Veronica, Mele, Vincenza Grazia, Chianese, Rosanna, de Lange, Pieter, Ricci, Giulia, Cioffi, Federica, Lanni, Antonia

“…This study aims to explore the complex role of cannabinoid type 1 receptor (CB1) signaling in the gastrocnemius muscle, assessing physiological processes in…”
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Both 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine Prevent Short-term Hepatic Lipid Accumulation via Distinct Mechanisms in Rats Being Fed a High-Fat Diet by Senese, Rosalba, Cioffi, Federica, de Lange, Pieter, Leanza, Cristina, Iannucci, Liliana F, Silvestri, Elena, Moreno, Maria, Lombardi, Assunta, Goglia, Fernando, Lanni, Antonia

“…3,3',5-triiodo-L-thyronine (T3) improves hepatic lipid accumulation by increasing lipid catabolism but it also increases lipogenesis, which at first glance…”
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3,5-Diiodo-L-Thyronine Exerts Metabolically Favorable Effects on Visceral Adipose Tissue of Rats Receiving a High-Fat Diet by Silvestri, Elena, Senese, Rosalba, Cioffi, Federica, De Matteis, Rita, Lattanzi, Davide, Lombardi, Assunta, Giacco, Antonia, Salzano, Anna Maria, Scaloni, Andrea, Ceccarelli, Michele, Moreno, Maria, Goglia, Fernando, Lanni, Antonia, de Lange, Pieter

“…When administered to rats receiving a high-fat diet (HFD), 3,5-diiodo-L-thyronine (3,5-T2) [at a dose of 25 μg/100 g body weight (BW)] is known to increase…”
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