Search Results - "DE LA ROSA, Vladimir"

SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity by Keiran, Noelia, Ceperuelo-Mallafré, Victoria, Calvo, Enrique, Hernández-Alvarez, Maria Isabel, Ejarque, Miriam, Núñez-Roa, Catalina, Horrillo, Daniel, Maymó-Masip, Elsa, Rodríguez, M. Mar, Fradera, Rosa, de la Rosa, Juan Vladimir, Jorba, Rosa, Megia, Ana, Zorzano, Antonio, Medina-Gómez, Gema, Serena, Carolina, Castrillo, Antonio, Vendrell, Joan, Fernández-Veledo, Sonia

“…Succinate is a signaling metabolite sensed extracellularly by succinate receptor 1 (SUNCR1). The accumulation of succinate in macrophages is known to activate…”
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MAFB Determines Human Macrophage Anti-Inflammatory Polarization: Relevance for the Pathogenic Mechanisms Operating in Multicentric Carpotarsal Osteolysis by Cuevas, Víctor D, Anta, Laura, Samaniego, Rafael, Orta-Zavalza, Emmanuel, Vladimir de la Rosa, Juan, Baujat, Geneviève, Domínguez-Soto, Ángeles, Sánchez-Mateos, Paloma, Escribese, María M, Castrillo, Antonio, Cormier-Daire, Valérie, Vega, Miguel A, Corbí, Ángel L

“…Macrophage phenotypic and functional heterogeneity derives from tissue-specific transcriptional signatures shaped by the local microenvironment. Most studies…”
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Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses by Vladimir de la Rosa, Juan, Tabraue, Carlos, Huang, Zhiqiang, Orizaola, Marta C., Martin‐Rodríguez, Patricia, Steffensen, Knut R., Zapata, Juan Manuel, Boscá, Lisardo, Tontonoz, Peter, Alemany, Susana, Treuter, Eckardt, Castrillo, Antonio

“…Macrophages regulate essential aspects of innate immunity against pathogens. In response to microbial components, macrophages activate primary and secondary…”
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Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages by Ramón-Vázquez, Ana, de la Rosa, Juan Vladimir, Tabraue, Carlos, Lopez, Felix, Díaz-Chico, Bonifacio Nicolas, Bosca, Lisardo, Tontonoz, Peter, Alemany, Susana, Castrillo, Antonio

“…The liver X receptors α and β (LXRα and LXRβ) are oxysterol-activated transcription factors that coordinately regulate gene expression that is important for…”
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LXR Signaling Regulates Macrophage Survival and Inflammation in Response to Ionizing Radiation by Tabraue, Carlos, Lara, Pedro C., De Mirecki-Garrido, Mercedes, De La Rosa, Juan Vladimir, López-Blanco, Félix, Fernández-Pérez, Leandro, Boscá, Lisardo, Castrillo, Antonio

“…To evaluate the role of liver X receptor (LXR) nuclear receptors on irradiation-induced cell death and polarization of macrophages and the potential…”
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Regulation of metabolic and transcriptional responses by the thyroid hormone in cellular models of murine macrophages by López-Mateo, Irene, Rodríguez-Muñoz, Diego, de La Rosa, Juan Vladimir, Castrillo, Antonio, Alemany, Susana, Aranda, Ana

“…Oncogene-immortalized bone marrow-derived macrophages are considered to be a good model for the study of immune cell functions, but the factors required for…”
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Activation of LXR Nuclear Receptors Impairs the Anti-Inflammatory Gene and Functional Profile of M-CSF-Dependent Human Monocyte-Derived Macrophages by González de la Aleja, Arturo, Herrero, Cristina, Torres-Torresano, Mónica, de la Rosa, Juan Vladimir, Alonso, Bárbara, Capa-Sardón, Enrique, Muller, Ittai B, Jansen, Gerrit, Puig-Kröger, Amaya, Vega, Miguel A, Castrillo, Antonio, Corbí, Ángel L

“…Liver X Receptors (LXR) control cholesterol metabolism and exert anti-inflammatory actions but their contribution to human macrophage polarization remains…”
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Fungal pattern receptors down‐regulate the inflammatory response by a cross‐inhibitory mechanism independent of interleukin‐10 production by Rodríguez, Mario, Márquez, Saioa, Rosa, Juan Vladimir, Alonso, Sara, Castrillo, Antonio, Sánchez Crespo, Mariano, Fernández, Nieves

“…Summary Cyclic AMP regulatory element binding protein and signal transducer and activator of transcription 3 (STAT3) may control inflammation by several…”
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Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver by Fernández-Pérez, Leandro, Guerra, Borja, Recio, Carlota, Cabrera-Galván, Juan José, García, Irma, De La Rosa, Juan Vladimir, Castrillo, Antonio, Iglesias-Gato, Diego, Díaz, Mario

“…Preclinical and clinical studies suggest that hypothyroidism might cause hepatic endocrine and metabolic disturbances with features that mimic deficiencies of…”
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Crosstalk Between LXR and Caveolin-1 Signaling Supports Cholesterol Efflux and Anti-Inflammatory Pathways in Macrophages by Ramírez, Cristina M, Torrecilla-Parra, Marta, Pardo-Marqués, Virginia, de-Frutos, Mario Fernández, Pérez-García, Ana, Tabraue, Carlos, de la Rosa, Juan Vladimir, Martín-Rodriguez, Patricia, Díaz-Sarmiento, Mercedes, Nuñez, Uxue, Orizaola, Marta C, Través, Paqui G, Camps, Marta, Boscá, Lisardo, Castrillo, Antonio

“…Macrophages are immune cells that play crucial roles in host defense against pathogens by triggering their exceptional phagocytic and inflammatory functions…”
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Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: relevance for their anti-tumor activity by Povo-Retana, Adrián, Fariñas, Marco, Landauro-Vera, Rodrigo, Mojena, Marina, Alvarez-Lucena, Carlota, Fernández-Moreno, Miguel A., Castrillo, Antonio, de la Rosa Medina, Juan Vladimir, Sánchez-García, Sergio, Foguet, Carles, Mas, Francesc, Marin, Silvia, Cascante, Marta, Boscá, Lisardo

“…In recent years, the central role of cell bioenergetics in regulating immune cell function and fate has been recognized, giving rise to the interest in…”
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Flow cytometric determination of lipid content in a marine dinoflagellate, Crypthecodinium cohnii by DE LA JARA, Adelina, MENDOZA, Héctor, MARTEL, Antera, MOLINA, Cristina, NORDSTRÖN, Laurette, DE LA ROSA, Vladimir, DIAZ, Ricardo

“…Since flow cytometry allows rapid, simultaneous and quantitative measurements related to cell morphology and physiologicy, the lipid-specific fluorescent dye,…”
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Analysis of LXR Nuclear Receptor Cistrome Through ChIP-Seq Data Bioinformatics by de la Rosa, Juan Vladimir, Ramón-Vázquez, Ana, Tabraue, Carlos, Castrillo, Antonio

“…Liver X receptors are members of the nuclear receptor superfamily of transcription factors. The LXR genes (NR1H2 and NR1H3) encode for two different proteins…”
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Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment by Carbó, José M, León, Theresa E, Font-Díaz, Joan, De la Rosa, Juan Vladimir, Castrillo, Antonio, Picard, Felix R, Staudenraus, Daniel, Huber, Magdalena, Cedó, Lídia, Escolà-Gil, Joan Carles, Campos, Lucía, Bakiri, Latifa, Wagner, Erwin F, Caelles, Carme, Stratmann, Thomas, Van Ginderachter, Jo A, Valledor, Annabel F

“…Liver X receptors (LXR) are transcription factors from the nuclear receptor family that are activated by oxysterols and synthetic high-affinity agonists. In…”
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Bone Marrow-Derived Macrophage Immortalization of LXR Nuclear Receptor-Deficient Cells by Ramón-Vázquez, Ana, de la Rosa, Juan Vladimir, Tabraue, Carlos, Castrillo, Antonio

“…Macrophages are professional phagocytic cells that play key roles in innate and adaptive immunity, metabolism, and tissue homeostasis. Lipid metabolism is…”
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