Search Results - "DE HOOGE, Alfons S. K"

Expression of Cellular FLICE Inhibitory Protein, Caspase-8, and Protease Inhibitor-9 in Ewing Sarcoma and Implications for Susceptibility to Cytotoxic Pathways by DE HOOGE, Alfons S. K, BERGHUIS, Dagmar, LANKESTER, Arjan C, SANTOS, Susyjusto, MOOIMAN, Esther, ROMEO, Salvatore, ALAIN KUMMER, J, MAARTEN EGELER, R, VAN TOL, Maarten J. D, MELIEF, Cornelis J. M, HOGENDOORN, Pancras C. W

“…Purpose: Ewing sarcoma is a common pediatric bone tumor with an unfavorable prognosis for metastatic or recurrent disease. Cellular immunotherapy may provide…”
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NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways by Verhoeven, Dirk H.J., de Hooge, Alfons S.K., Mooiman, Esther C.K., Santos, Susy Justo, ten Dam, Monique M., Gelderblom, Hans, Melief, Cornelis J.M., Hogendoorn, Pancras C.W., Egeler, R. Maarten, van Tol, Maarten J.D., Schilham, Marco W., Lankester, Arjan C.

“…Ewing sarcoma (EWS) is a malignant bone-associated sarcoma, with poor prognosis in case of metastasis or relapse. To explore the feasibility of natural killer…”
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Involvement of IL-6, Apart from Its Role in Immunity, in Mediating a Chronic Response during Experimental Arthritis by de Hooge, Alfons S.K., van de Loo, Fons A.J., Arntz, Onno J., van den Berg, Wim B.

“…Interleukin-6 (IL-6) is highly produced during arthritis but its exact function is still unknown. In this study we examined if IL-6, apart from its role in…”
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Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-κB Ligand by de Hooge, Alfons S.K., van de Loo, Fons A.J., Bennink, Miranda B., de Jong, Diana S., Arntz, Onno J., Lubberts, Erik, Richards, Carl D., van den Berg, Wim B.

“…Oncostatin M (OSM) has been described as a bone-remodeling factor either stimulating osteoblast activity or osteoclast formation in vitro. To elucidate the in…”
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Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition by Berghuis, Dagmar, de Hooge, Alfons SK, Santos, Susy J, Horst, Danielle, Wiertz, Emmanuel J, van Eggermond, Marja C, van den Elsen, Peter J, Taminiau, Antonie HM, Ottaviano, Laura, Schaefer, Karl-Ludwig, Dirksen, Uta, Hooijberg, Erik, Mulder, Arend, Melief, Cornelis JM, Egeler, R. Maarten, Schilham, Marco W, Jordanova, Ekaterina S, Hogendoorn, Pancras CW, Lankester, Arjan C

“…Ewing sarcoma (EWS) is a tumour most commonly arising in bone, although on occasion in soft tissue, with a poor prognosis in patients with refractory or…”
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Local activation of STAT‐1 and STAT‐3 in the inflamed synovium during zymosan‐induced arthritis: Exacerbation of joint inflammation in STAT‐1 gene–knockout mice by de Hooge, Alfons S. K., van de Loo, Fons A. J., Koenders, Marije I., Bennink, Miranda B., Arntz, Onno J., Kolbe, Thomas, van den Berg, Wim B.

“…Objective STAT proteins play an important role in cytokine signaling. Some investigators have reported preferential activation of STAT‐1, and others have…”
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Splenic suppressor of cytokine signaling 3 transgene expression affects T cell responses and prevents development of collagen‐induced arthritis by Veenbergen, Sharon, Bennink, Miranda B., de Hooge, Alfons S. K., Arntz, Onno J., Smeets, Ruben L., van den Berg, Wim B., van de Loo, Fons A. J.

“…Objective Members of the suppressor of cytokine signaling (SOCS) family are key negative intracellular regulators of cytokine and growth factor responses,…”
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Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-{kappa}B Ligand by de Hooge, Alfons S. K, van de Loo, Fons A. J, Bennink, Miranda B, de Jong, Diana S, Arntz, Onno J, Lubberts, Erik, Richards, Carl D, van den Berg, Wim B

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Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: A comparative study in gene‐deficient mice by de Hooge, Alfons S. K., van de Loo, Fons A. J., Bennink, Miranda B., Arntz, Onno J., Fiselier, Theo J. W., Franssen, Marcel J. A. M., Joosten, Leo A. B., van Lent, Peter L. E. M., Richards, Carl D., van den Berg, Wim B.

“…Objective To investigate the involvement of proinflammatory and destructive mediators in oncostatin M (OSM)–induced joint pathology, using gene‐deficient mice…”
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Male IL-6 gene knock out mice developed more advanced osteoarthritis upon aging by de Hooge, Alfons S.K., van de Loo, Fons A.J., Bennink, Miranda B., Arntz, Onno J., de Hooge, Pieter, van den Berg, Wim B.

“…Interleukin-6 (IL-6) is expressed in osteoarthritic joints but its function in osteoarthritis (OA) is unknown. To study this, spontaneous and experimental OA…”
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