Search Results - "DE GUNZBURG, J"
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Spatiotemporal regulation of the Pak1 kinase
Published in Biochemical Society transactions (01-08-2005)“…Pak1 (p21-activated kinase 1) is a key regulator of the actin cytoskeleton, adhesion and cell motility. Such biological roles require a tight spatial and…”
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Investigation of the effect of the adsorbent DAV131A on the propensity of moxifloxacin to induce simulated Clostridioides (Clostridium) difficile infection (CDI) in an in vitro human gut model
Published in Journal of antimicrobial chemotherapy (01-06-2020)“…Clostridioides difficile infection (CDI) remains a high burden worldwide. DAV131A, a novel adsorbent, reduces residual gut antimicrobial levels, reducing CDI…”
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Erythromycin degradation by esterase (EreB) in enzymatic membrane reactors
Published in Biochemical engineering journal (15-10-2016)“…Free and immobilized EreB exhibited an effective removal of Erythromycin.Effect of pH and temperature on EreB activity.Different enzymatic membrane reactor…”
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Design and optimization of an enzymatic membrane reactor for tetracycline degradation
Published in Catalysis today (01-11-2014)“…•Laccase grafting onto ceramic supports for active membrane elaboration.•Impact of different parameters on laccase activity.•Tetracycline degradation by free…”
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Determination of structural requirements for the interaction of Rab6 with RabGDI and Rab geranylgeranyltransferase
Published in The Journal of biological chemistry (06-05-1994)“…The importance of geranylgeranylation to the interaction of Rab proteins with RabGDI was investigated with a set of Rab6 mutants post-translationally modified…”
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Cloning and cDNA sequence of the regulatory subunit of cAMP-dependent protein kinase from Dictyostelium discoideum
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1987)“…cDNA clones encoding the regulatory subunit of the cAMP-dependent protein kinase (ATP:protein phosphotransferase, EC 2.7.1.37) from Dictyostelium discoideum…”
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Thrombopoietin-Mediated Sustained Activation of Extracellular Signal-Regulated Kinase in UT7-Mpl Cells Requires Both Ras–Raf-1- and Rap1–B-Raf-Dependent Pathways
Published in Molecular and Cellular Biology (01-04-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Purification and Characterization of Smooth Muscle Cell Caveolae
Published in The Journal of cell biology (01-07-1994)“…Plasmalemmal caveolae are a membrane specialization that mediates transcytosis across endothelial cells and the uptake of small molecules and ions by both…”
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Specific inhibition of phorbol ester-stimulated phospholipase D by Clostridium sordellii lethal toxin and Clostridium difficile toxin B-1470 in HEK-293 cells. Restoration by Ral GTPases
Published in The Journal of biological chemistry (27-03-1998)“…Activation of m3 muscarinic acetylcholine receptor (mAChR), stably expressed in human embryonic kidney (HEK)-293 cells, leads to phospholipase D (PLD)…”
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Association of rap1 and rap2 proteins with the specific granules of human neutrophils. Translocation to the plasma membrane during cell activation
Published in The Journal of biological chemistry (25-03-1992)“…Activation of human neutrophils involves the degranulation of specific and azurophil granules. This process is GTP-dependent and the presence of small…”
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1043P A review of meta-analyses on the impact of antibiotics on the efficacy of immune checkpoint inhibitors and cancer patients’ survival
Published in Annals of oncology (01-09-2020)Get full text
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Expression of the TSC2 product tuberin and its target Rap1 in normal human tissues
Published in The American journal of pathology (01-01-1997)“…The tuberous sclerosis-2 (TSC2) gene is linked to tuberous sclerosis (TSC), a dominantly inherited genetic syndrome in which inactivation of the normal TSC2…”
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Association of the Ras-Antagonistic Rap1/Krev-1 Proteins with the Golgi Complex
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1991)“…Ras oncogenes encode 21-kDa GTP-binding proteins that are capable of transforming immortalized cells in culture. Ras proteins are bound to the inner face of…”
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Ultrastructural localization of the small GTP-binding protein Rap1 in human platelets and megakaryocytes
Published in British journal of haematology (01-10-1994)“…Several functions have been proposed for Rap1B in human platelets, including the regulation of phospholipase (PL) C gamma and Ca2+ ATPase. However, its…”
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Protein interaction mapping: a Drosophila case study
Published in Genome research (01-03-2005)“…The Drosophila (fruit fly) model system has been instrumental in our current understanding of human biology, development, and diseases. Here, we used a…”
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p21ras-Induced Responsiveness of Phosphatidylinositol Turnover to Bradykinin is a Receptor Number Effect
Published in Proceedings of the National Academy of Sciences - PNAS (01-08-1988)“…Proteins encoded by ras genes have recently been reported to couple certain growth factor receptors to phospholipase C, the enzyme catalyzing…”
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Correlated expression of the 97 kDa sarcoendoplasmic reticulum Ca(2+)-ATPase and Rap1B in platelets and various cell lines
Published in Biochemical journal (15-01-1994)“…Evidence has accumulated that cyclic AMP (cAMP)-induced phosphorylation of a Ras-related protein (Rap1) regulates platelet Ca2+ transport. As this transport…”
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The product of the rap2 gene, member of the ras superfamily. Biochemical characterization and site-directed mutagenesis
Published in The Journal of biological chemistry (05-03-1991)“…The human rap2 gene encodes a 183 amino acid protein that shares 46% identity with the K-ras p21. Its cDNA was engineered and inserted into the bacterial…”
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