Search Results - "DE GROOTH, G. J"

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    Cholesteryl ester transfer protein concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS) by Klerkx, A. H. E. M., De Grooth, G. J., Zwinderman, A. H., Jukema, J. W., Kuivenhoven, J. A., Kastelein, J. J. P.

    Published in European journal of clinical investigation (01-01-2004)
    “…Background  The TaqIB polymorphism in the cholesteryl ester transfer protein (CETP) gene is associated with HDL‐C, progression of coronary artery disease (CAD)…”
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    Journal Article
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    Effectiveness of Inhibition of Cholesteryl Ester Transfer Protein by JTT-705 in Combination With Pravastatin in Type II Dyslipidemia by Kuivenhoven, Jan Albert, de Grooth, Greetje J., Kawamura, Hitoshi, Klerkx, Anke H., Wilhelm, Francois, Trip, Mieke D., Kastelein, John J.P.

    Published in The American journal of cardiology (01-05-2005)
    “…The inhibition of cholesteryl ester transfer protein (CETP) has recently been shown to effectively increase high-density lipoprotein (HDL) cholesterol. This…”
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    Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study by DE GROOTH, Greetje J, KUIVENHOVEN, Jan Albert, STALENHOEF, Anton F. H, DE GRAAF, Jacqueline, ZWINDERMAN, Aeilko H, POSMA, Jan L, VAN TOL, Arie, KASTELEIN, John J. P

    Published in Circulation (New York, N.Y.) (07-05-2002)
    “…Cholesteryl ester transfer protein (CETP) mediates the transfer of neutral lipids between lipoproteins. High plasma levels of CETP are correlated with low HDL…”
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    A review of CETP and its relation to atherosclerosis by de Grooth, Greetje J., Klerkx, Anke H.E.M., Stroes, Erik S.G., Stalenhoef, Anton F.H., Kastelein, John J.P., Kuivenhoven, Jan Albert

    Published in Journal of lipid research (01-11-2004)
    “…Although the atheroprotective role of HDL cholesterol (HDL-c) is well documented, effective therapeutics to selectively increase plasma HDL-c levels are not…”
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    Journal Article
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    Enhancing reverse cholesterol transport/raising HDL cholesterol: new options for prevention and treatment of cardiovascular disease by Jukema, J W, Lenselink, M, de Grooth, G J, Boekholdt, S M, Liem, A H, Kuivenhoven, J-A, Kastelein, J J P

    Published in Netherlands heart journal (01-11-2004)
    “…High-density lipoprotein cholesterol (HDL-c) plays a crucial role in the concept of reverse cholesterol transport and has many other beneficial properties…”
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