Search Results - "DE GROOT, R. P"

Hormonal control of gene expression: multiplicity and versatility of cyclic adenosine 3',5'-monophosphate-responsive nuclear regulators by de Groot, R P, Sassone-Corsi, P

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Lineage-specific activation of STAT3 by interferon-gamma in human neutrophils by Caldenhoven, Eric, Buitenhuis, Miranda, Djk, Thamar B., Raaijmakers, Jan A. M., Lammers, Jan‐Willem J., Koenderman, Leo, Groot, Rolf P.

“…Binding of interferon‐γ (IFN‐γ) to its heterodimeric receptor induces activation of the tyrosine kinases JAK1 and JAK2 followed by tyrosine phosphorylation of…”
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Alternative Usage of Initiation Codons in mRNA Encoding the cAMP- Responsive-Element Modulator Generates Regulators with Opposite Functions by Delmas, Veronique, Laoide, Brid M., Masquilier, Denis, de Groot, Rolf P., Foulkes, Nicholas S., Sassone-Corsi, Paolo

“…The cAMP-responsive-element modulator (CREM) gene encodes both antagonists (CREMα/beta/gamma) and an activator (CREMτ) of cAMP-responsive transcription by…”
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Growth hormone induces expression of c-jun and jun B oncogenes and employs a protein kinase C signal transduction pathway for the induction of c-fos oncogene expression by Slootweg, M C, de Groot, R P, Herrmann-Erlee, M P, Koornneef, I, Kruijer, W, Kramer, Y M

“…Although the structure of several members of the GH receptor family has been defined, signal transduction following GH binding to its receptor has not been…”
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Stat3 Activation by Src Induces Specific Gene Regulation and Is Required for Cell Transformation by Turkson, James, Bowman, Tammy, Garcia, Roy, Caldenhoven, Eric, De Groot, Rolf P., Jove, Richard

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multiple and cooperative phosphorylation events regulate the CREM activator function by Groot, R.P., Hertog, J., Vandenheede, J.R., Goris, J., Sassone‐Corsi, P.

“…Phosphorylation is one of the major mechanisms by which the activity of transcription factors can be regulated. We have investigated the role of…”
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The role of STATs in myeloid differentiation and leukemia by Coffer, P J, Koenderman, L, de Groot, R P

“…Myeloid differentiation is a highly regulated process governed by various cytokines, such as EPO, TPO, G-CSF, IL-3, IL-5 and GM-CSF. These cytokines act in…”
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Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy by de Groot, R P, Auwerx, J, Bourouis, M, Sassone-Corsi, P

“…Transcription factor AP-1 is constituted by the products of the various fos and jun genes. AP-1 activity is modulated by second messengers and appears to…”
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C/EBP regulates the promoter of the eosinophil-derived neurotoxin/RNS2 gene in human eosinophilic cells by Baltus, Belinda, Buitenhuis, Miranda, Dijk, Thamar B., Vinson, Charles, Raaijmakers, Jan A. M., Lammers, Jan‐Willem J., Koenderman, Leo, Groot, Rolf P.

“…The eosinophil‐derived neurotoxin (EDN), a member of the mammalian ribonuclease family, is found in the large specific granules of human eosinophilic…”
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Regulation of Proliferation, Differentiation and Survival by the IL-3/IL-5/GM-CSF Receptor Family by de Groot, Rolf P., Coffer, Paul J., Koenderman, Leo

“…The receptors for the Il-3/IL-5/GM-CSF cytokine family are composed of a heterodimeric complex of a cytokine-specific α chain and a common β chain (βc)…”
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STAT5 Activation by BCR-Abl Contributes to Transformation of K562 Leukemia Cells by de Groot, Rolf P., Raaijmakers, Jan A.M., Lammers, Jan-Willem J., Jove, Richard, Koenderman, Leo

“…Signal transducers and activators of transcription (STATs) belong to a family of transcription factors that were originally identified as mediators of…”
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Regulation and function of protein kinase B and MAP kinase activation by the IL-5/GM-CSF/IL-3 receptor by DIJKERS, P. F, VAN DIJK, T. B, DE GROOT, R. P, RAAIJMAKERS, J. A, LAMMERS, J.-W. J, KOENDERMAN, L, COFFER, P. J

“…Interleukin (IL)-3, IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) regulate proliferation, differentiation and apoptosis of target cells…”
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Activation of junB by PKC and PKA signal transduction through a novel cis-acting element by DE GROOT, R. P, AUWERX, J, KARPERIEN, M, STAELS, B, KRUIJER, W

“…The product of the junB gene, a gene homologous to the proto-oncogene c-jun, is a component of transcription factor AP-1. JunB expression is modulated by a…”
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Activation of Jun/AP-1 by protein kinase A by de Groot, R P, Sassone-Corsi, P

“…The product of the c-jun proto-oncogene is the major component of the 12-O-tetradecanoyl phorbol 13-acetate (TPA)-inducible transcription factor AP-1. Jun…”
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Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expression by de Groot, R P, Ballou, L M, Sassone-Corsi, P

“…Activation of the adenylyl cyclase signaling pathway elicits the induction of genes via activators binding to cAMP-responsive elements (CREs). Nuclear factor…”
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Ectopic expression of c‐jun leads to differentiation of P19 embryonal carcinoma cells by Groot, R.P., Kruyt, F.A., Saag, P.T., Kruijer, W.

“…The product of the c‐jun proto‐oncogene, a major component of the transcription factor AP1, has been implicated in both positive and negative transcriptional…”
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Cloning and characterization of FcαRb, a novel Fcα receptor (CD89) isoform expressed in eosinophils and neutrophils by VAN DIJK, T. B, BRACKE, M, CALDENHOVEN, E, RAAIJMAKERS, J. A. M, LAMMERS, J.-W. J, KOENDERMAN, L, DE GROOT, R. P

“…The Fc receptor for IgA (Fc alpha R, CD89) is a transmembrane glycoprotein found on monocytes, macrophages, neutrophils, and eosinophils. Here we describe the…”
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Phosphorylation and negative regulation of the transcriptional activator CREM by p34cdc2 by de Groot, R P, Derua, R, Goris, J, Sassone-Corsi, P

“…Transcription factors that bind to cAMP-responsive elements (CREs) regulate the expression of target genes in response to activation of the adenylyl cyclase…”
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Leptin treatment increases suppressors of cytokine signaling in central and peripheral tissues by Emilsson, Valur, Arch, Jonathan R.S., de Groot, Rolf P., Lister, Carolyn A., Cawthorne, Michael A.

“…Leptin concentrations are elevated in the majority of obese individuals raising the possibility that leptin resistance contributes to their obesity. Peripheral…”
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Transcriptional control of c-jun by retinoic acid by DE GROOT, R. P, PALS, C, KRUIJER, W

“…The proto-oncogene c-jun, a major component of transcription factor AP-1, is expressed at very low levels in undifferentiated embryonal carcinoma (EC) end…”
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