Search Results - "DE GROOT, Joris R"
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Two-incision technique for implantation of the subcutaneous implantable cardioverter-defibrillator
Published in Heart rhythm (01-08-2013)“…Background Three incisions in the chest are necessary for implantation of the entirely subcutaneous implantable cardioverter-defibrillator (S-ICD). The…”
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2
Neutrophil degranulation interconnects over-represented biological processes in atrial fibrillation
Published in Scientific reports (03-02-2021)“…Despite our expanding knowledge about the mechanism underlying atrial fibrillation (AF), the interplay between the biological events underlying AF remains…”
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3
Implantable cardioverter-defibrillator harm in young patients with inherited arrhythmia syndromes: A systematic review and meta-analysis of inappropriate shocks and complications
Published in Heart rhythm (01-02-2016)“…Background Implantable cardioverter-defibrillators (ICDs) are implanted with the intention to prolong life in selected patients with inherited arrhythmia…”
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4
Sudden Cardiac Death in Adult Congenital Heart Disease
Published in Circulation (New York, N.Y.) (16-10-2012)“…Sudden cardiac death (SCD) is a major cause of mortality in adults with congenital heart disease (CHD). The aim of this study was to determine the adult CHD…”
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5
ElectroMap: High-throughput open-source software for analysis and mapping of cardiac electrophysiology
Published in Scientific reports (04-02-2019)“…The ability to record and analyse electrical behaviour across the heart using optical and electrode mapping has revolutionised cardiac research. However, wider…”
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6
PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers
Published in Journal of the American College of Cardiology (25-10-2016)“…Abstract Background Antiarrhythmic drugs are widely used to treat patients with atrial fibrillation (AF), but the mechanisms conveying their variable…”
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7
MicroRNAs in Atrial Fibrillation: from Expression Signatures to Functional Implications
Published in Cardiovascular drugs and therapy (01-06-2017)“…Atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with pronounced morbidity and mortality. Its prevalence, expected to further…”
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8
Chronic Performance of a Leadless Cardiac Pacemaker
Published in Journal of the American College of Cardiology (21-04-2015)“…Abstract Background A leadless cardiac pacemaker (LCP) system was recently introduced to overcome lead-related complications of conventional pacing systems. To…”
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9
Treatment of Atrial and Ventricular Arrhythmias Through Autonomic Modulation
Published in JACC. Clinical electrophysiology (01-12-2015)“…Abstract This paper reviews the contribution of autonomic nervous system (ANS) modulation in the treatment of arrhythmias. Both the atria and ventricles are…”
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10
Secretome of atrial epicardial adipose tissue facilitates reentrant arrhythmias by myocardial remodeling
Published in Heart rhythm (01-09-2022)“…Epicardial adipose tissue (EAT) accumulation is associated with cardiac arrhythmias. The effect of EAT secretome (EATs) on cardiac electrophysiology remains…”
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11
Inappropriate subcutaneous implantable cardioverter-defibrillator shocks due to T-wave oversensing can be prevented: Implications for management
Published in Heart rhythm (01-03-2014)“…Background Inappropriate shocks (IASs) complicate implantable cardioverter-defibrillator (ICD) therapy. The management of IASs in patients with a subcutaneous…”
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12
Differential Sodium Current Remodelling Identifies Distinct Cellular Proarrhythmic Mechanisms in Paroxysmal vs Persistent Atrial Fibrillation
Published in Canadian journal of cardiology (01-03-2023)“…The cellular mechanisms underlying progression from paroxysmal to persistent atrial fibrillation (AF) are not fully understood, but alterations in (late)…”
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13
Primary cilia suppress the fibrotic activity of atrial fibroblasts from patients with atrial fibrillation in vitro
Published in Scientific reports (30-05-2024)“…Atrial fibrosis serves as an arrhythmogenic substrate in atrial fibrillation (AF) and contributes to AF persistence. Treating atrial fibrosis is challenging…”
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14
Intermediate-term outcome of cryoballoon ablation of persistent atrial fibrillation and improvements in quality of life of patients
Published in PloS one (21-01-2022)“…Clinical outcome of pulmonary vein isolation (PVI) has been predominantly focused on the reoccurrence of atrial fibrillation (AF) and the maintenance of sinus…”
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15
Atrial inflammation and microvascular thrombogenicity are increased in deceased COVID-19 patients
Published in Cardiovascular pathology (01-05-2023)“…•Inflammation, cardiomyocyte injury and microvascular thrombosis are increased in the atria of the heart in COVID-19 patients.•The increased inflammation and…”
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Reduced left atrial cardiomyocyte PITX2 and elevated circulating BMP10 predict atrial fibrillation after ablation
Published in JCI insight (20-08-2020)“…BACKGROUNDGenomic and experimental studies suggest a role for PITX2 in atrial fibrillation (AF). To assess if this association is relevant for recurrent AF in…”
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17
Knockdown of Ift88 in fibroblasts causes extracellular matrix remodeling and decreases conduction velocity in cardiomyocyte monolayers
Published in Frontiers in physiology (17-11-2022)“…Background: Atrial fibrosis plays an important role in the development and persistence of atrial fibrillation by promoting reentry. Primary cilia have been…”
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Patch-Clamp Recordings of Action Potentials From Human Atrial Myocytes: Optimization Through Dynamic Clamp
Published in Frontiers in pharmacology (12-04-2021)“…Atrial fibrillation (AF) is the most common cardiac arrhythmia. Consequently, novel therapies are being developed. Ultimately, the impact of compounds on the…”
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Characteristics of patients initiated on edoxaban in Europe: baseline data from edoxaban treatment in routine clinical practice for patients with atrial fibrillation (AF) in Europe (ETNA-AF-Europe)
Published in BMC cardiovascular disorders (12-07-2019)“…Non-vitamin K antagonist (VKA) oral anticoagulants (NOACs) have substantially improved anticoagulation therapy for prevention of stroke and systemic embolism…”
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Efficacy of Antiarrhythmic Drugs in Adults With Congenital Heart Disease and Supraventricular Tachycardias
Published in The American journal of cardiology (01-11-2013)“…Supraventricular tachycardias (SVTs) are a major cause of morbidity in adults with congenital heart disease (CHD). Few data exist on safety and efficacy of…”
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