Search Results - "DE FERRARI, GAETANO M."

Ranolazine in the treatment of atrial fibrillation: Results of the dose-ranging RAFFAELLO (Ranolazine in Atrial Fibrillation Following An ELectricaL CardiOversion) study by De Ferrari, Gaetano M., MD, Maier, Lars S., MD, Mont, Lluís, MD, PhD, Schwartz, Peter J., MD, FAHA, FHRS, Simonis, Gregor, MD, Leschke, Matthias, MD, Gronda, Edoardo, MD, Boriani, Giuseppe, MD, PhD, Darius, Harald, MD, Guillamón Torán, Laura, MD, Savelieva, Irene, MD, PhD, Dusi, Veronica, MD, Marchionni, Niccolò, MD, Quintana Rendón, Miguel, MD, PhD, Schumacher, Kai, MD, Tonini, Giulia, PhD, Melani, Lorenzo, MD, PhD, Giannelli, Stefano, MD, Alberto Maggi, Carlo, MD, John Camm, A., MD, FHRS

“…Background Currently available antiarrhythmic agents for the treatment of atrial fibrillation (AF) have important limitations, leaving an unmet need for safe…”
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Left cardiac sympathetic denervation for the prevention of life-threatening arrhythmias: The surgical supraclavicular approach to cervicothoracic sympathectomy by Odero, Attilio, MD, Bozzani, Antonio, MD, De Ferrari, Gaetano M., MD, Schwartz, Peter J., MD, FHRS

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Right Ventricular–Pulmonary Arterial Coupling in Secondary Tricuspid Regurgitation by Fortuni, Federico, Butcher, Steele C., Dietz, Marlieke F., van der Bijl, Pieter, Prihadi, Edgard A., De Ferrari, Gaetano M., Ajmone Marsan, Nina, Bax, Jeroen J., Delgado, Victoria

“…Chronic pressure-overload induces right ventricular (RV) adaptation to maintain RV–pulmonary arterial (PA) coupling. RV remodeling is frequently associated…”
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Vagal stimulation for heart failure: Background and first in-man study by Schwartz, Peter J., MD, FHRS, De Ferrari, Gaetano M., MD

“…This article reviews the background and rationale that have led to the first in-man study of the effects of direct chronic vagal stimulation for the management…”
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Clinical neurocardiology defining the value of neuroscience‐based cardiovascular therapeutics by Shivkumar, Kalyanam, Ajijola, Olujimi A., Anand, Inder, Armour, J. Andrew, Chen, Peng‐Sheng, Esler, Murray, Ferrari, Gaetano M., Fishbein, Michael C., Goldberger, Jeffrey J., Harper, Ronald M., Joyner, Michael J., Khalsa, Sahib S., Kumar, Rajesh, Lane, Richard, Mahajan, Aman, Po, Sunny, Schwartz, Peter J., Somers, Virend K., Valderrabano, Miguel, Vaseghi, Marmar, Zipes, Douglas P.

“…The autonomic nervous system regulates all aspects of normal cardiac function, and is recognized to play a critical role in the pathophysiology of many…”
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Chronic vagal stimulation for the treatment of low ejection fraction heart failure: results of the NEural Cardiac TherApy foR Heart Failure (NECTAR-HF) randomized controlled trial by Zannad, Faiez, De Ferrari, Gaetano M, Tuinenburg, Anton E, Wright, David, Brugada, Josep, Butter, Christian, Klein, Helmut, Stolen, Craig, Meyer, Scott, Stein, Kenneth M, Ramuzat, Agnes, Schubert, Bernd, Daum, Doug, Neuzil, Petr, Botman, Cornelis, Castel, Maria Angeles, D'Onofrio, Antonio, Solomon, Scott D, Wold, Nicholas, Ruble, Stephen B

“…The neural cardiac therapy for heart failure (NECTAR-HF) was a randomized sham-controlled trial designed to evaluate whether a single dose of vagal nerve…”
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Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE by Gaba, Prakriti, O’Donoghue, Michelle L., Park, Jeong-Gun, Wiviott, Stephen D., Atar, Dan, Kuder, Julia F., Im, KyungAh, Murphy, Sabina A., De Ferrari, Gaetano M., Gaciong, Zbigniew A., Toth, Kalman, Gouni-Berthold, Ioanna, Lopez-Miranda, Jose, Schiele, François, Mach, François, Flores-Arredondo, Jose H., López, J. Antonio G., Elliott-Davey, Mary, Wang, Bei, Monsalvo, Maria Laura, Abbasi, Siddique, Giugliano, Robert P., Sabatine, Marc S.

“…Low-density lipoprotein cholesterol (LDL-C) is a well-established risk factor for atherosclerotic cardiovascular disease. However, the optimal achieved LDL-C…”
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Prognostic Implications of a Novel Algorithm to Grade Secondary Tricuspid Regurgitation by Fortuni, Federico, Dietz, Marlieke F., Prihadi, Edgard A., van der Bijl, Pieter, De Ferrari, Gaetano M., Knuuti, Juhani, Bax, Jeroen J., Delgado, Victoria, Marsan, Nina Ajmone

“…A novel tricuspid regurgitation (TR) grading system, using vena contracta (VC) width and effective regurgitant orifice area (EROA), was proposed and validated…”
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Impact of atrial fibrillation catheter ablation on mortality, stroke, and heart failure hospitalizations: A meta‐analysis by Saglietto, Andrea, De Ponti, Roberto, Di Biase, Luigi, Matta, Mario, Gaita, Fiorenzo, Romero, Jorge, De Ferrari, Gaetano M., Anselmino, Matteo

“…Background The impact of atrial fibrillation catheter ablation (AFCA) on hard clinical endpoints remains controversial. Objective Our aim was to conduct a…”
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Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes by Rocchetti, Marcella, Sala, Luca, Dreizehnter, Lisa, Crotti, Lia, Sinnecker, Daniel, Mura, Manuela, Pane, Luna Simona, Altomare, Claudia, Torre, Eleonora, Mostacciuolo, Gaspare, Severi, Stefano, Porta, Alberto, De Ferrari, Gaetano M, George, Jr, Alfred L, Schwartz, Peter J, Gnecchi, Massimiliano, Moretti, Alessandra, Zaza, Antonio

“…Calmodulin (CaM) is a small protein, encoded by three genes (CALM1-3), exerting multiple Ca2+-dependent modulatory roles. A mutation (F142L) affecting only one…”
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Chronic vagus nerve stimulation: a new and promising therapeutic approach for chronic heart failure by DE FERRARI, Gaetano M, CRIJNS, Harry J. G. M, RASPOPOVIC, Srdjan, KLEIN, Helmut, SWEDBERG, Karl, SCHWARTZ, Peter J, BORGGREFE, Martin, MILASINOVIC, Goran, SMID, Jan, ZABEL, Markus, GAVAZZI, Antonello, SANZO, Antonio, DENNERT, Robert, KUSCHYK, Juergen

“…In chronic heart failure (CHF), reduced vagal activity correlates with increased mortality and acute decompensation. Experimentally, chronic vagus nerve…”
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The sympathetic nervous system and arrhythmogenic right ventricular cardiomyopathy: Further evidence of a strong tie by Dusi, Veronica, De Ferrari, Gaetano M.

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Safety and efficacy of ezetimibe: A meta-analysis by Savarese, Gianluigi, De Ferrari, Gaetano M, Rosano, Giuseppe M.C, Perrone-Filardi, Pasquale

“…Abstract Background The addition of ezetimibe to statin therapy has been widely demonstrated to significantly reduce low-density lipoprotein cholesterol…”
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Long-term vagal stimulation for heart failure: Eighteen month results from the NEural Cardiac TherApy foR Heart Failure (NECTAR-HF) trial by De Ferrari, Gaetano M, Stolen, Craig, Tuinenburg, Anton E, Jay Wright, D, Brugada, Josep, Butter, Christian, Klein, Helmut, Neuzil, Petr, Botman, Cornelis, Castel, Maria Angeles, D'Onofrio, Antonio, De Borst, Gert Jan, Solomon, Scott, Stein, Kenneth M, Schubert, Bernd, Stalsberg, Kevin, Wold, Nicholas, Ruble, Stephen, Zannad, Faiez

“…Abstract Background The NECTAR-HF study evaluated safety and feasibility of vagal nerve stimulation (VNS) for the treatment of heart failure patients. The…”
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Rationale and design of the effect of evolocumab in patients at high cardiovascular risk without prior myocardial infarction or stroke (VESALIUS-CV) trial by Bohula, Erin A., Marston, Nicholas A., Ruzza, Andrea, Murphy, Sabina A., De Ferrari, Gaetano M., Diaz, Rafael, Leiter, Lawrence A., Elliott-Davey, Mary, Wang, Huei, Bhatia, Ajay K., Giugliano, Robert P., Sabatine, Marc S.

“…The reduction of low-density lipoprotein cholesterol (LDL-C) with evolocumab, a fully human monoclonal antibody inhibitor of proprotein convertase…”
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Echocardiographic estimation of right ventricular wall tension: haemodynamic comparison and long-term follow-up by Annone, Umberto, Bocchino, Pier P., Marra, Walter G., D’Ascenzo, Fabrizio, Magnino, Corrado, Montefusco, Antonio, Omedè, Pierluigi, Veglio, Franco, Milan, Alberto, de Ferrari, Gaetano M.

“…Prognosis in pulmonary hypertension is strictly linked to right ventricle failure, which results from uncoupling between right ventricle function and its…”
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Chemokines and Heart Disease: A Network Connecting Cardiovascular Biology to Immune and Autonomic Nervous Systems by De Ferrari, Gaetano M., Ravera, Alice, Ghidoni, Alice, Dusi, Veronica, Calvillo, Laura

“…Among the chemokines discovered to date, nineteen are presently considered to be relevant in heart disease and are involved in all stages of cardiovascular…”
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Left Cardiac Sympathetic Denervation for Catecholaminergic Polymorphic Ventricular Tachycardia by Wilde, Arthur A.M, Bhuiyan, Zahurul A, Crotti, Lia, Facchini, Mario, De Ferrari, Gaetano M, Paul, Thomas, Ferrandi, Chiara, Koolbergen, Dave R, Odero, Attilio, Schwartz, Peter J

“…A surgical procedure for cardiac sympathetic denervation successfully controlled recurrent polymorphic ventricular tachycardia in three patients with a…”
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Vorapaxar for secondary prevention of thrombotic events for patients with previous myocardial infarction: a prespecified subgroup analysis of the TRA 2°P-TIMI 50 trial by Scirica, Benjamin M, Dr, Bonaca, Marc P, MD, Braunwald, Eugene, Prof, De Ferrari, Gaetano M, MD, Isaza, Daniel, MD, Lewis, Basil S, Prof, Mehrhof, Felix, MD, Merlini, Piera A, Prof, Murphy, Sabina A, MPH, Sabatine, Marc S, MD, Tendera, Michal, Prof, Van de Werf, Frans, Prof, Wilcox, Robert, Prof, Morrow, David A, MD

“…Summary Background Vorapaxar inhibits platelet activation by antagonising thrombin-mediated activation of the protease-activated receptor 1 on human platelets…”
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Sympathetic–parasympathetic interaction in health and disease: abnormalities and relevance in heart failure by Schwartz, Peter J., De Ferrari, Gaetano M.

“…Sympathetic–parasympathetic interaction plays a major role in the evolution and outcome of many cardiovascular disorders. Nonetheless, a thorough understanding…”
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