Search Results - "DE FABIANI, Emma"

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning by Ferrari, Alessandra, Longo, Raffaella, Fiorino, Erika, Silva, Rui, Mitro, Nico, Cermenati, Gaia, Gilardi, Federica, Desvergne, Béatrice, Andolfo, Annapaola, Magagnotti, Cinzia, Caruso, Donatella, Fabiani, Emma De, Hiebert, Scott W., Crestani, Maurizio

“…White adipose tissue (WAT) can undergo a phenotypic switch, known as browning, in response to environmental stimuli such as cold. Post-translational…”
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Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy by Mitro, Nico, Cermenati, Gaia, Brioschi, Elisabetta, Abbiati, Federico, Audano, Matteo, Giatti, Silvia, Crestani, Maurizio, De Fabiani, Emma, Azcoitia, Inigo, Garcia-Segura, Luis Miguel, Caruso, Donatella, Melcangi, Roberto Cosimo

“…Diabetic peripheral neuropathy causes a decrease in the levels of dihydroprogesterone and 5α-androstane-3α,17β-diol (3α-diol) in the peripheral nerves. These…”
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Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function by Audano, Matteo, Ferrari, Alessandra, Fiorino, Erika, Kuenzl, Martin, Caruso, Donatella, Mitro, Nico, Crestani, Maurizio, De Fabiani, Emma

“…Energy metabolism and mitochondrial function hold a core position in cellular homeostasis. Oxidative metabolism is regulated at multiple levels, ranging from…”
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PGC1s and Beyond: Disentangling the Complex Regulation of Mitochondrial and Cellular Metabolism by Coppi, Lara, Ligorio, Simona, Mitro, Nico, Caruso, Donatella, De Fabiani, Emma, Crestani, Maurizio

“…Metabolism is the central engine of living organisms as it provides energy and building blocks for many essential components of each cell, which are required…”
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Ketogenic Diet: A New Light Shining on Old but Gold Biochemistry by Longo, Raffaella, Peri, Carolina, Cricrì, Dalma, Coppi, Lara, Caruso, Donatella, Mitro, Nico, De Fabiani, Emma, Crestani, Maurizio

“…Diets low in carbohydrates and proteins and enriched in fat stimulate the hepatic synthesis of ketone bodies (KB). These molecules are used as alternative fuel…”
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Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue by GALMOZZI, Andrea, MITRO, Nico, VALENTE, Sergio, GUERRINI, Uliano, CARUSO, Donatella, MAI, Antonello, SAEZ, Enrique, DE FABIANI, Emma, CRESTANI, Maurizio, FERRARI, Alessandra, GERS, Elise, GILARDI, Federica, GODIO, Cristina, CERMENATI, Gaia, GUALERZI, Alice, DONETTI, Elena, ROTILI, Dante

“…Chromatin modifications are sensitive to environmental and nutritional stimuli. Abnormalities in epigenetic regulation are associated with metabolic disorders…”
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Atomistic description of the OCTN1 recognition mechanism via in silico methods by Ben Mariem, Omar, Palazzolo, Luca, Torre, Beatrice, Wei, Yao, Bianchi, Davide, Guerrini, Uliano, Laurenzi, Tommaso, Saporiti, Simona, De Fabiani, Emma, Pochini, Lorena, Indiveri, Cesare, Eberini, Ivano

“…The Organic Cation Transporter Novel 1 (OCTN1), also known as SLC22A4, is widely expressed in various human tissues, and involved in numerous physiological and…”
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When food meets man: the contribution of epigenetics to health by De Fabiani, Emma, Mitro, Nico, Gilardi, Federica, Galmozzi, Andrea, Caruso, Donatella, Crestani, Maurizio

“…Post-translational modifications of chromatin contribute to the epigenetic control of gene transcription. The response to food intake and individual nutrients…”
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Targeting lipid metabolism to starve and stop cancer cells by Fabiani, Emma De

“…The “unusual” turnover of fatty acids in cancer cells Anabolic reactions, including fatty acid synthesis, are enhanced in proliferating cancer cells. Several…”
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Histone Deacetylase 3 Regulates Adipocyte Phenotype at Early Stages of Differentiation by Cricrí, Dalma, Coppi, Lara, Pedretti, Silvia, Mitro, Nico, Caruso, Donatella, De Fabiani, Emma, Crestani, Maurizio

“…Obesity is a condition characterized by uncontrolled expansion of adipose tissue mass resulting in pathological weight gain. Histone deacetylases (HDACs) have…”
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Ellagitannins from Castanea sativa Mill. Leaf Extracts Impair H. pylori Viability and Infection-Induced Inflammation in Human Gastric Epithelial Cells by Piazza, Stefano, Martinelli, Giulia, Fumagalli, Marco, Pozzoli, Carola, Maranta, Nicole, Giavarini, Flavio, Colombo, Luca, Nicotra, Giovanna, Vicentini, Silvia Francesca, Genova, Francesca, De Fabiani, Emma, Sangiovanni, Enrico, Dell'Agli, Mario

“…( ) is an etiologic factor of peptic ulcer disease and gastric cancer. Virulent strains of are correlated with the severity of gastritis, due to NF-κB…”
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Investigating the Molecular Mechanisms Underlying Early Response to Inflammation and Helicobacter pylori Infection in Human Gastric Epithelial Cells by Martinelli, Giulia, Fumagalli, Marco, Piazza, Stefano, Maranta, Nicole, Genova, Francesca, Sperandeo, Paola, Sangiovanni, Enrico, Polissi, Alessandra, Dell’Agli, Mario, De Fabiani, Emma

“…Helicobacter pylori is a leading cause of chronic gastric inflammation, generally associated with gastritis and adenocarcinoma. Activation of the NF-κB pathway…”
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Strawberry tannins inhibit IL-8 secretion in a cell model of gastric inflammation by Fumagalli, Marco, Sangiovanni, Enrico, Vrhovsek, Urska, Piazza, Stefano, Colombo, Elisa, Gasperotti, Mattia, Mattivi, Fulvio, De Fabiani, Emma, Dell’Agli, Mario

“…[Display omitted] In the present study we chemically profiled tannin-enriched extracts from strawberries and tested their biological properties in a cell model…”
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Lack of Sterol Regulatory Element Binding Factor-1c Imposes Glial Fatty Acid Utilization Leading to Peripheral Neuropathy by Cermenati, Gaia, Audano, Matteo, Giatti, Silvia, Carozzi, Valentina, Porretta-Serapiglia, Carla, Pettinato, Emanuela, Ferri, Cinzia, D’Antonio, Maurizio, De Fabiani, Emma, Crestani, Maurizio, Scurati, Samuele, Saez, Enrique, Azcoitia, Iñigo, Cavaletti, Guido, Garcia-Segura, Luis-Miguel, Melcangi, Roberto C., Caruso, Donatella, Mitro, Nico

“…Myelin is a membrane characterized by high lipid content to facilitate impulse propagation. Changes in myelin fatty acid (FA) composition have been associated…”
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Study of 1,4-Dihydropyridine Structural Scaffold: Discovery of Novel Sirtuin Activators and Inhibitors by Mai, Antonello, Valente, Sergio, Meade, Sarah, Carafa, Vincenzo, Tardugno, Maria, Nebbioso, Angela, Galmozzi, Andrea, Mitro, Nico, De Fabiani, Emma, Altucci, Lucia, Kazantsev, Aleksey

“…NAD+-dependent sirtuin deacetylases have emerged as potential therapeutic targets for treatment of human illnesses such as cancer, metabolic, cardiovascular,…”
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Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation by Cermenati, Gaia, Abbiati, Federico, Cermenati, Solei, Brioschi, Elisabetta, Volonterio, Alessandro, Cavaletti, Guido, Saez, Enrique, De Fabiani, Emma, Crestani, Maurizio, Garcia-Segura, Luis M., Melcangi, Roberto C., Caruso, Donatella, Mitro, Nico

“…Diabetic peripheral neuropathy (DPN) is characterized by myelin abnormalities; however, the molecular mechanisms underlying such deficits remain obscure. To…”
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The sirtuin class of histone deacetylases: Regulation and roles in lipid metabolism by Fiorino, Erika, Giudici, Marco, Ferrari, Alessandra, Mitro, Nico, Caruso, Donatella, De Fabiani, Emma, Crestani, Maurizio

“…After the completion of the human genome sequence and that from many other organisms, last decade has witnessed a spectacular gain of knowledge on gene…”
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"The Loss of Golden Touch": Mitochondria-Organelle Interactions, Metabolism, and Cancer by Audano, Matteo, Pedretti, Silvia, Ligorio, Simona, Crestani, Maurizio, Caruso, Donatella, De Fabiani, Emma, Mitro, Nico

“…Mitochondria represent the energy hub of cells and their function is under the constant influence of their tethering with other subcellular organelles…”
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Coordinated Control of Cholesterol Catabolism to Bile Acids and of Gluconeogenesis via a Novel Mechanism of Transcription Regulation Linked to the Fasted-to-fed Cycle by De Fabiani, Emma, Mitro, Nico, Gilardi, Federica, Caruso, Donatella, Galli, Giovanni, Crestani, Maurizio

“…Bile acid metabolism plays an essential role in cholesterol homeostasis and is critical for the initiation of atherosclerotic disease. However, despite the…”
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Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease by Crosignani, Andrea, Del Puppo, Marina, Longo, Matteo, De Fabiani, Emma, Caruso, Donatella, Zuin, Massimo, Podda, Mauro, Javitt, Norman B., Kienle, Marzia Galli

“…Cholesterol elimination occurs through bile acid synthesis that starts within the liver from 7α-hydroxylation or in extrahepatic tissues from 27-hydroxylation…”
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