Search Results - "DE DOMENICO, Elena"

A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation by Hansen, Jan N, Kaiser, Fabian, Leyendecker, Philipp, Stüven, Birthe, Krause, Jens‐Henning, Derakhshandeh, Fatemeh, Irfan, Jaazba, Sroka, Tommy J, Preval, Kenley M, Desai, Paurav B, Kraut, Michael, Theis, Heidi, Drews, Anna‐Dorothee, De‐Domenico, Elena, Händler, Kristian, Pazour, Gregory J, Henderson, David J P, Mick, David U, Wachten, Dagmar

“…The primary cilium constitutes an organelle that orchestrates signal transduction independently from the cell body. Dysregulation of this intricate molecular…”
Get full text

Analysis of the early response to spinal cord injury identified a key role for mTORC1 signaling in the activation of neural stem progenitor cells by Peñailillo, Johany, Palacios, Miriam, Mounieres, Constanza, Muñoz, Rosana, Slater, Paula G., De Domenico, Elena, Patrushev, Ilya, Gilchrist, Mike, Larraín, Juan

“…Xenopus laevis are able to regenerate the spinal cord during larvae stages through the activation of neural stem progenitor cells (NSPCs). Here we use…”
Get full text

Neutrophils in COVID-19 by Reusch, Nico, De Domenico, Elena, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Baßler, Kevin, Schultze, Joachim L, Aschenbrenner, Anna C

“…Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that neutrophils play an important role in the pathophysiology, particularly…”
Get full text

High-resolution analysis of gene activity during the Xenopus mid-blastula transition by Collart, Clara, Owens, Nick D L, Bhaw-Rosun, Leena, Cooper, Brook, De Domenico, Elena, Patrushev, Ilya, Sesay, Abdul K, Smith, James N, Smith, James C, Gilchrist, Michael J

“…The Xenopus mid-blastula transition (MBT) marks the onset of large-scale zygotic transcription, as well as an increase in cell cycle length and a loss of…”
Get full text

Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease by Kapellos, Theodore S., Baßler, Kevin, Fujii, Wataru, Nalkurthi, Christina, Schaar, Anna C., Bonaguro, Lorenzo, Pecht, Tal, Galvao, Izabela, Agrawal, Shobhit, Saglam, Adem, Dudkin, Erica, Frishberg, Amit, de Domenico, Elena, Horne, Arik, Donovan, Chantal, Kim, Richard Y., Gallego-Ortega, David, Gillett, Tessa E., Ansari, Meshal, Schulte-Schrepping, Jonas, Offermann, Nina, Antignano, Ignazio, Sivri, Burcu, Lu, Wenying, Eapen, Mathew S., van Uelft, Martina, Osei-Sarpong, Collins, van den Berge, Maarten, Donker, Hylke C., Groen, Harry J.M., Sohal, Sukhwinder S., Klein, Johanna, Schreiber, Tina, Feißt, Andreas, Yildirim, Ali Önder, Schiller, Herbert B., Nawijn, Martijn C., Becker, Matthias, Händler, Kristian, Beyer, Marc, Capasso, Melania, Ulas, Thomas, Hasenauer, Jan, Pizarro, Carmen, Theis, Fabian J., Hansbro, Philip M., Skowasch, Dirk, Schultze, Joachim L.

“…Systemic inflammation is established as part of late-stage severe lung disease, but molecular, functional, and phenotypic changes in peripheral immune cells in…”
Get full text

Molecular asymmetry in the 8-cell stage Xenopus tropicalis embryo described by single blastomere transcript sequencing by De Domenico, Elena, Owens, Nick D.L., Grant, Ian M., Gomes-Faria, Rosa, Gilchrist, Michael J.

“…Correct development of the vertebrate body plan requires the early definition of two asymmetric, perpendicular axes. The first axis is established during…”
Get full text

Optimized workflow for single-cell transcriptomics on infectious diseases including COVID-19 by De Domenico, Elena, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Becker, Matthias, Händler, Kristian, Schultze, Joachim L.

“…In December 2019, a new coronavirus, SARS-CoV-2, which causes the respiratory illness that led to the COVID-19 pandemic, was reported. In the face of such a…”
Get full text

A multibiomarker approach in Coris julis living in a natural environment by Fasulo, Salvatore, Marino, Sergio, Mauceri, Angela, Maisano, Maria, Giannetto, Alessia, D'Agata, Alessia, Parrino, Vincenzo, Minutoli, Roberta, De Domenico, Elena

“…To monitor the health of aquatic organisms, biomarkers have been used as effective tools in assessing environmental risk. In this study was examined the…”
Get full text

Chromatin accessibility profiling of targeted cell populations with laser capture microdissection coupled to ATAC-seq by Carraro, Caterina, Bonaguro, Lorenzo, Srinivasa, Rachana, van Uelft, Martina, Isakzai, Victoria, Schulte-Schrepping, Jonas, Gambhir, Prerna, Elmzzahi, Tarek, Montgomery, Jessica V., Hayer, Hannah, Li, Yuanfang, Theis, Heidi, Kraut, Michael, Mahbubani, Krishnaa T., Aschenbrenner, Anna C., König, Ireen, Fava, Eugenio, Fried, Hans-Ulrich, De Domenico, Elena, Beyer, Marc, Saglam, Adem, Schultze, Joachim L.

“…Spatially resolved omics technologies reveal context-dependent cellular regulatory networks in tissues of interest. Beyond transcriptome analysis, information…”
Get full text

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients by Aschenbrenner, Anna C, Mouktaroudi, Maria, Krämer, Benjamin, Oestreich, Marie, Antonakos, Nikolaos, Nuesch-Germano, Melanie, Gkizeli, Konstantina, Bonaguro, Lorenzo, Reusch, Nico, Baßler, Kevin, Saridaki, Maria, Knoll, Rainer, Pecht, Tal, Kapellos, Theodore S, Doulou, Sarandia, Kröger, Charlotte, Herbert, Miriam, Holsten, Lisa, Horne, Arik, Gemünd, Ioanna D, Rovina, Nikoletta, Agrawal, Shobhit, Dahm, Kilian, van Uelft, Martina, Drews, Anna, Lenkeit, Lena, Bruse, Niklas, Gerretsen, Jelle, Gierlich, Jannik, Becker, Matthias, Händler, Kristian, Kraut, Michael, Theis, Heidi, Mengiste, Simachew, De Domenico, Elena, Schulte-Schrepping, Jonas, Seep, Lea, Raabe, Jan, Hoffmeister, Christoph, ToVinh, Michael, Keitel, Verena, Rieke, Gereon, Talevi, Valentina, Skowasch, Dirk, Aziz, N Ahmad, Pickkers, Peter, van de Veerdonk, Frank L, Netea, Mihai G, Schultze, Joachim L, Kox, Matthijs, Breteler, Monique M B, Nattermann, Jacob, Koutsoukou, Antonia, Giamarellos-Bourboulis, Evangelos J, Ulas, Thomas

“…The SARS-CoV-2 pandemic is currently leading to increasing numbers of COVID-19 patients all over the world. Clinical presentations range from asymptomatic,…”
Get full text

Metabolomic investigation of Mytilus galloprovincialis (Lamarck 1819) caged in aquatic environments by Fasulo, Salvatore, Iacono, Francesco, Cappello, Tiziana, Corsaro, Carmelo, Maisano, Maria, D'Agata, Alessia, Giannetto, Alessia, De Domenico, Elena, Parrino, Vincenzo, Lo Paro, Giuseppe, Mauceri, Angela

“…Environmental metabolomics was applied to assess the metabolic responses in transplanted mussels to environmental pollution. Specimens of Mytilus…”
Get full text

Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus by Duy, Phan Q., Weise, Stefan C., Marini, Claudia, Li, Xiao-Jun, Liang, Dan, Dahl, Peter J., Ma, Shaojie, Spajic, Ana, Dong, Weilai, Juusola, Jane, Kiziltug, Emre, Kundishora, Adam J., Koundal, Sunil, Pedram, Maysam Z., Torres-Fernández, Lucia A., Händler, Kristian, De Domenico, Elena, Becker, Matthias, Ulas, Thomas, Juranek, Stefan A., Cuevas, Elisa, Hao, Le Thi, Jux, Bettina, Sousa, André M. M., Liu, Fuchen, Kim, Suel-Kee, Li, Mingfeng, Yang, Yiying, Takeo, Yutaka, Duque, Alvaro, Nelson-Williams, Carol, Ha, Yonghyun, Selvaganesan, Kartiga, Robert, Stephanie M., Singh, Amrita K., Allington, Garrett, Furey, Charuta G., Timberlake, Andrew T., Reeves, Benjamin C., Smith, Hannah, Dunbar, Ashley, DeSpenza, Tyrone, Goto, June, Marlier, Arnaud, Moreno-De-Luca, Andres, Yu, Xin, Butler, William E., Carter, Bob S., Lake, Evelyn M. R., Constable, R. Todd, Rakic, Pasko, Lin, Haifan, Deniz, Engin, Benveniste, Helene, Malvankar, Nikhil S., Estrada-Veras, Juvianee I., Walsh, Christopher A., Alper, Seth L., Schultze, Joachim L., Paeschke, Katrin, Doetzlhofer, Angelika, Wulczyn, F. Gregory, Jin, Sheng Chih, Lifton, Richard P., Sestan, Nenad, Kolanus, Waldemar, Kahle, Kristopher T.

“…Hydrocephalus, characterized by cerebral ventricular dilatation, is routinely attributed to primary defects in cerebrospinal fluid (CSF) homeostasis. This…”
Get full text

The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation by Knoll, Rainer, Helbig, Elisa T, Dahm, Kilian, Bolaji, Olufemi, Hamm, Frederik, Dietrich, Oliver, van Uelft, Martina, Müller, Sophie, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Petrov, Lev, Krämer, Benjamin, Kraut, Michael, Stubbemann, Paula, Thibeault, Charlotte, Brumhard, Sophia, Theis, Heidi, Hack, Gudrun, De Domenico, Elena, Nattermann, Jacob, Becker, Matthias, Beyer, Marc D, Hillus, David, Georg, Philipp, Loers, Constantin, Tiedemann, Janina, Tober-Lau, Pinkus, Lippert, Lena, Millet Pascual-Leone, Belén, Tacke, Frank, Rohde, Gernot, Suttorp, Norbert, Witzenrath, Martin, Saliba, Antoine-Emmanuel, Ulas, Thomas, Polansky, Julia K, Sawitzki, Birgit, Sander, Leif E, Schultze, Joachim L, Aschenbrenner, Anna C, Kurth, Florian

“…Dexamethasone is a life-saving treatment for severe COVID-19, yet its mechanism of action is unknown, and many patients deteriorate or die despite timely…”
Get more information

Biological responses of juvenile European sea bass (Dicentrarchus labrax) exposed to contaminated sediments by De Domenico, Elena, Mauceri, Angela, Giordano, Daniela, Maisano, Maria, Giannetto, Alessia, Parrino, Vincenzo, Natalotto, Antonino, D’Agata, Alessia, Cappello, Tiziana, Fasulo, Salvatore

“…Multiple anthropogenic activities present along coastal environments may affect the health status of aquatic ecosystems. In this study, specimens of European…”
Get full text

Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation by Baßler, Kevin, Fujii, Wataru, Kapellos, Theodore S, Dudkin, Erika, Reusch, Nico, Horne, Ari, Reiz, Benedikt, Luecken, Malte D, Osei-Sarpong, Collins, Warnat-Herresthal, Stefanie, Bonaguro, Lorenzo, Schulte-Schrepping, Jonas, Wagner, Allon, Günther, Patrick, Pizarro, Carmen, Schreiber, Tina, Knoll, Rainer, Holsten, Lisa, Kröger, Charlotte, De Domenico, Elena, Becker, Matthias, Händler, Kristian, Wohnhaas, Christian T, Baumgartner, Florian, Köhler, Meike, Theis, Heidi, Kraut, Michael, Wadsworth, 2nd, Marc H, Hughes, Travis K, Ferreira, Humberto J, Hinkley, Emily, Kaltheuner, Ines H, Geyer, Matthias, Thiele, Christoph, Shalek, Alex K, Feißt, Andreas, Thomas, Daniel, Dickten, Henning, Beyer, Marc, Baum, Patrick, Yosef, Nir, Aschenbrenner, Anna C, Ulas, Thomas, Hasenauer, Jan, Theis, Fabian J, Skowasch, Dirk, Schultze, Joachim L

“…Despite its high prevalence, the cellular and molecular mechanisms of chronic obstructive pulmonary disease (COPD) are far from being understood. Here, we…”
Get full text

Influence of continuous light treatment on expression of stress biomarkers in Atlantic cod by Giannetto, Alessia, Fernandes, Jorge M.O., Nagasawa, Kazue, Mauceri, Angela, Maisano, Maria, De Domenico, Elena, Cappello, Tiziana, Oliva, Sabrina, Fasulo, Salvatore

“…•Genes involved in oxidative stress were differentially expressed with photoperiod.•Photoperiod modulates liver transcript levels of key antimicrobial…”
Get full text

Effects of “ in vivo” exposure to toxic sediments on juveniles of sea bass ( Dicentrarchus labrax) by De Domenico, Elena, Mauceri, Angela, Giordano, Daniela, Maisano, Maria, Gioffrè, Giuseppina, Natalotto, Antonino, D’Agata, Alessia, Ferrante, Margherita, Brundo, Maria Violetta, Fasulo, Salvatore

“…► Impact of heavy metals in the sediments on Dicentrarchus labrax. ► Gills as organ target. ► Detoxification action by Metallothioneins. ► Alteration of the…”
Get full text

Ultrastructural and immunohistochemical investigation on the gills of the teleost, Thalassoma pavo L., exposed to cadmium by Brunelli, Elvira, Mauceri, Angela, Maisano, Maria, Bernabò, Ilaria, Giannetto, Alessia, De Domenico, Elena, Corapi, Barbara, Tripepi, Sandro, Fasulo, Salvatore

“…An investigation was conducted to determine the effects of the heavy metal, cadmium (Cd), on the gills of the teleost fish, Thalassoma pavo Linnaeus, 1758. The…”
Get full text

Cellular and Molecular Mechanism of Spinal Cord Regeneration in the Frog Xenopus laevis by Larrain, Juan, Edwards, Gabriela, Lee-Liu, Dasfne, Mendez, Emilio, Peñailillo, Johany, Muñoz, Rosana, Guzman, Daniel, Sun, Liangliang, De Domenico, Elena, Cebrian-Silla, Arantxa, Dovichi, Norman, Gilchrist, Mike, Garcia-verdugo, Jose Manuel, Faunes, Fernando

Get full text

Phylogenetic relationships of the Antarctic euphausiids inhabiting the Ross Sea and the adjacent regions of Southern Ocean by GIORDANO, Daniela, RINELLI, Paola, RUSSO, Aniello, SALA, Antonello, AZZALI, Massimo, LA SPADA, Gina, GIULIANO, Laura, CRISAFI, Ermanno, DE DOMENICO, Elena, YAKIMOV, Michail

“…Ross Sea supports a large concentration of Antarctic krill (Euphausia superba Dana, 1850) and Ice krill (Euphausia crystallorophias Holt & Tattersal, 1906)…”
Get full text