Search Results - "DE COURTEN, Maximilian P. J"
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Effects of carnosine supplementation on glucose metabolism: Pilot clinical trial
Published in Obesity (Silver Spring, Md.) (01-05-2016)“…Objective Carnosine is a naturally present dipeptide in humans and an over‐the counter food additive. Evidence from animal studies supports the role for…”
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Higher glomerular filtration rate is related to insulin resistance but not to obesity in a predominantly obese non-diabetic cohort
Published in Scientific reports (03-04-2017)“…Glomerular hyperfiltration has been associated with obesity, insulin resistance, and systolic blood pressure (SBP). However, previous studies are limited by…”
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Muscle Carnosine Is Associated with Cardiometabolic Risk Factors in Humans
Published in PloS one (06-10-2015)“…Carnosine is a naturally present dipeptide abundant in skeletal muscle and an over-the counter food additive. Animal data suggest a role of carnosine…”
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Carnosine Supplementation Improves Serum Resistin Concentrations in Overweight or Obese Otherwise Healthy Adults: A Pilot Randomized Trial
Published in Nutrients (07-09-2018)“…Adipokines play an important role in the regulation of glucose metabolism. We have previously shown that carnosine supplementation in overweight or obese…”
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5
complex immunological and inflammatory network of adipose tissue in obesity
Published in Molecular nutrition & food research (01-01-2016)“…A number of approaches have been utilized in the prevention, management, and treatment of obesity, including, surgery, medication, diet, exercise, and overall…”
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Effect of vitamin D supplementation on inflammation and nuclear factor kappa-B activity in overweight/obese adults: a randomized placebo-controlled trial
Published in Scientific reports (09-11-2017)“…In-vitro studies suggest that vitamin D reduces inflammation by inhibiting nuclear factor kappa-B (NFκB) activity. Yet, no trials have examined the effects of…”
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Vitamin D supplementation increases adipokine concentrations in overweight or obese adults
Published in European journal of nutrition (01-02-2020)“…Purpose Vitamin D regulates adipokine production in vitro; however, clinical trials have been inconclusive. We conducted secondary analyses of a randomized…”
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Carnosine supplementation reduces plasma soluble transferrin receptor in healthy overweight or obese individuals: a pilot randomised trial
Published in Amino acids (01-01-2019)“…Abnormalities of iron homeostasis have been linked to insulin resistance, type 2 diabetes and cardiovascular disease. Carnosine, an over-the-counter food…”
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Author Correction: Effect of carnosine supplementation on the plasma lipidome in overweight and obese adults: a pilot randomised controlled trial
Published in Scientific reports (04-03-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Vitamin D supplementation may improve back pain disability in vitamin D deficient and overweight or obese adults
Published in The Journal of steroid biochemistry and molecular biology (01-01-2019)“…•This trial investigated the effects of vitamin D supplementation on back pain.•Vitamin D in severely deficient, overweight/obese adults reduced back pain…”
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Effect of dietary advanced glycation end products on inflammation and cardiovascular risks in healthy overweight adults: a randomised crossover trial
Published in Scientific reports (23-06-2017)“…Diets high in advanced glycation end products (AGEs) are thought to be detrimental to cardiovascular health. However, there remains uncertainty about the…”
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Adipsin Concentrations Are Associated with Back Pain Independently of Adiposity in Overweight or Obese Adults
Published in Frontiers in physiology (12-02-2018)“…To compare cardiometabolic risk factors including cytokine and adipokine concentrations between individuals with and without back pain. In 62 overweight/obese…”
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Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects
Published in Amino acids (01-02-2014)“…It has been postulated that chronic exposure to high levels of advanced glycation end products (AGEs), in particular from dietary sources, can impair insulin…”
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Effect of carnosine supplementation on the plasma lipidome in overweight and obese adults: a pilot randomised controlled trial
Published in Scientific reports (12-12-2017)“…Carnosine has been shown to reduce oxidation and glycation of low density lipoprotein hence improving dyslipidaemia in rodents. The effect of carnosine on…”
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Targeted reduction of advanced glycation improves renal function in obesity
Published in Kidney international (01-07-2011)“…Obesity is highly prevalent in Western populations and is considered a risk factor for the development of renal impairment. Interventions that reduce the…”
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25-hydroxyvitamin D is associated with adiposity and cardiometabolic risk factors in a predominantly vitamin D-deficient and overweight/obese but otherwise healthy cohort
Published in The Journal of steroid biochemistry and molecular biology (01-10-2017)“…•25-hydroxyvitamin D levels were associated with cardiometabolic risk factors including adiposity, glucose intolerance, insulin resistance, and inflammation in…”
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The Role of Traditional Cardiovascular Risk Factors Among Patients with Rheumatoid Arthritis
Published in Journal of rheumatology (01-01-2009)“…Objective People with rheumatoid arthritis (RA) have an increased risk of cardiovascular disease (CVD) compared with the general population. We investigated…”
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Vitamin D and symptoms of depression in overweight or obese adults: A cross-sectional study and randomized placebo-controlled trial
Published in The Journal of steroid biochemistry and molecular biology (01-03-2018)“…•Serum 25-hydroxyvitamin D (25(OH)D) concentrations were not related to depressive symptoms (Beck Depression Inventory [BDI]) in young adults.•Vitamin D…”
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Insulin infusion reduces hepatocyte growth factor in lean humans
Published in Metabolism, clinical and experimental (01-05-2013)“…Abstract Objective Plasma Hepatocyte Growth Factor (HGF) is significantly elevated in obesity and may contribute to vascular disease, metabolic syndrome or…”
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Vitamin D supplementation improves waist-to-hip ratio and fasting blood glucose in vitamin D deficient, overweight or obese Asians: A pilot secondary analysis of a randomised controlled trial
Published in The Journal of steroid biochemistry and molecular biology (01-02-2019)“…•We previously reported no effects of vitamin D supplements in overweight/obesity.•In a subset of Asians, vitamin D improved waist-hip ratio and fasting…”
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