Search Results - "DE CASTRO, Gilberto"

Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer by Carnielli, Carolina Moretto, Macedo, Carolina Carneiro Soares, De Rossi, Tatiane, Granato, Daniela Campos, Rivera, César, Domingues, Romênia Ramos, Pauletti, Bianca Alves, Yokoo, Sami, Heberle, Henry, Busso-Lopes, Ariane Fidelis, Cervigne, Nilva Karla, Sawazaki-Calone, Iris, Meirelles, Gabriela Vaz, Marchi, Fábio Albuquerque, Telles, Guilherme Pimentel, Minghim, Rosane, Ribeiro, Ana Carolina Prado, Brandão, Thaís Bianca, de Castro, Gilberto, González-Arriagada, Wilfredo Alejandro, Gomes, Alexandre, Penteado, Fabio, Santos-Silva, Alan Roger, Lopes, Márcio Ajudarte, Rodrigues, Priscila Campioni, Sundquist, Elias, Salo, Tuula, da Silva, Sabrina Daniela, Alaoui-Jamali, Moulay A., Graner, Edgard, Fox, Jay W., Coletta, Ricardo Della, Paes Leme, Adriana Franco

“…Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological and molecular characteristics limiting the standard…”
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Exercise prescription for symptoms and quality of life improvements in lung cancer patients: a systematic review by Codima, Alberto, das Neves Silva, Willian, de Souza Borges, Ana Paula, de Castro, Gilberto

“…Purpose The purpose of this study was to conduct a systematic review to assess the effect of exercise on symptoms and quality of life in lung cancer patients…”
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Review: Side Effects of Approved Molecular Targeted Therapies in Solid Cancers by Widakowich, Christian, de Castro, Gilberto, de Azambuja, Evandro, Dinh, Phuong, Awada, Ahmad

“…Learning Objectives After completing this course, the reader will be able to: List the molecular targeted agents that are considered standard practice in solid…”
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Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial by Herbst, Roy S, Prof, Baas, Paul, Prof, Kim, Dong-Wan, MD, Felip, Enriqueta, MD, Pérez-Gracia, José L, MD, Han, Ji-Youn, Prof, Molina, Julian, MD, Kim, Joo-Hang, Prof, Arvis, Catherine Dubos, MD, Ahn, Myung-Ju, Prof, Majem, Margarita, MD, Fidler, Mary J, MD, de Castro, Gilberto, MD, Garrido, Marcelo, MD, Lubiniecki, Gregory M, MD, Shentu, Yue, PhD, Im, Ellie, MD, Dolled-Filhart, Marisa, PhD, Garon, Edward B, MD

“…Summary Background Despite recent advances in the treatment of advanced non-small-cell lung cancer, there remains a need for effective treatments for…”
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First-line ceritinib versus platinum-based chemotherapy in advanced ALK -rearranged non-small-cell lung cancer (ASCEND-4): a randomised, open-label, phase 3 study by Soria, Jean-Charles, Prof, Tan, Daniel S W, MD, Chiari, Rita, MD, Wu, Yi-Long, Prof, Paz-Ares, Luis, Prof, Wolf, Juergen, Prof, Geater, Sarayut L, MD, Orlov, Sergey, Prof, Cortinovis, Diego, MD, Yu, Chong-Jen, Prof, Hochmair, Maximillian, MD, Cortot, Alexis B, Prof, Tsai, Chun-Ming, Prof, Moro-Sibilot, Denis, MD, Campelo, Rosario G, MD, McCulloch, Tracey, MSc, Sen, Paramita, PhD, Dugan, Margaret, MD, Pantano, Serafino, PhD, Branle, Fabrice, MD, Massacesi, Cristian, MD, de Castro, Gilberto, MD

“…Summary Background The efficacy of ceritinib in patients with untreated anaplastic lymphoma kinase ( ALK )-rearranged non-small-cell lung cancer (NSCLC) is not…”
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A phase 2 study of first‐line nivolumab in patients with locally advanced or metastatic cutaneous squamous‐cell carcinoma by Munhoz, Rodrigo R., Nader‐Marta, Guilherme, Camargo, Veridiana P., Queiroz, Marcello M., Cury‐Martins, Jade, Ricci, Hermínia, Mattos, Marcela R., Menezes, Thiago A. F., Machado, Guilherme U. C., Bertolli, Eduardo, Barros, Milton, Souza, Carina E., Franke, Fábio, Ferreira, Fabio O., Feher, Olavo, Castro, Gilberto

“…Background Cutaneous squamous‐cell carcinoma (CSCC) is among the most frequent malignancies worldwide. For those not amenable to treatment with curative…”
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Serum Creatinine as a Potential Biomarker of Skeletal Muscle Atrophy in Non-small Cell Lung Cancer Patients by das Neves, Willian, Alves, Christiano R R, de Souza Borges, Ana Paula, de Castro, Jr, Gilberto

“…Identifying simple biomarkers to determine muscle atrophy in non-small-cell lung cancer (NSCLC) patients remains a critical research gap. Since creatinine is…”
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Pembrolizumab With or Without Chemotherapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: Updated Results of the Phase III KEYNOTE-048 Study by Harrington, Kevin J, Burtness, Barbara, Greil, Richard, Soulières, Denis, Tahara, Makoto, de Castro, Jr, Gilberto, Psyrri, Amanda, Brana, Irene, Basté, Neus, Neupane, Prakash, Bratland, Åse, Fuereder, Thorsten, Hughes, Brett G M, Mesia, Ricard, Ngamphaiboon, Nuttapong, Rordorf, Tamara, Wan Ishak, Wan Zamaniah, Lin, Jianxin, Gumuscu, Burak, Swaby, Ramona F, Rischin, Danny

“…Pembrolizumab and pembrolizumab-chemotherapy demonstrated efficacy in recurrent/metastatic head and neck squamous cell carcinoma in KEYNOTE-048. Post hoc…”
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Extraoral photobiomodulation for prevention of oral and oropharyngeal mucositis in head and neck cancer patients: interim analysis of a randomized, double-blind, clinical trial by Kauark-Fontes, Elisa, Migliorati, Cesar Augusto, Epstein, Joel B., Treister, Nathaniel Simon, Alves, Carolina Guimarães Bonfim, Faria, Karina Morais, Palmier, Natalia Rangel, Rodrigues-Oliveira, Leticia, de Pauli Paglioni, Mariana, Gueiros, Luiz Alcino Monteiro, da Conceição Vasconcelos, Karina G. M., de Castro, Gilberto, Leme, Adriana Franco Paes, Lopes, Marcio Ajudarte, Prado-Ribeiro, Ana Carolina, Brandão, Thaís Bianca, Santos-Silva, Alan Roger

“…Purpose To assess the safety and efficacy of prophylactic extraoral photobiomodulation (PBM) for the prevention of oral and oropharyngeal mucositis (OM) on…”
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Oral Mucositis Prevention By Low-Level Laser Therapy in Head-and-Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy: A Phase III Randomized Study by Gouvêa de Lima, Aline, D.D.S., M.Sc, Villar, Rosângela Correa, M.D., Ph.D, de Castro, Gilberto, M.D., Ph.D, Antequera, Reynaldo, D.D.S, Gil, Erlon, M.D, Rosalmeida, Mauro Cabral, M.D, Federico, Miriam Hatsue Honda, M.D., Ph.D, Snitcovsky, Igor Moisés Longo, M.D., Ph.D

“…Purpose Oral mucositis is a major complication of concurrent chemoradiotherapy (CRT) in head-and-neck cancer patients. Low-level laser (LLL) therapy is a…”
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Lung cancer in Brazil by Araujo, Luiz Henrique, Baldotto, Clarissa, Castro, Jr, Gilberto de, Katz, Artur, Ferreira, Carlos Gil, Mathias, Clarissa, Mascarenhas, Eldsamira, Lopes, Gilberto de Lima, Carvalho, Heloisa, Tabacof, Jaques, Martínez-Mesa, Jeovany, Viana, Luciano de Souza, Cruz, Marcelo de Souza, Zukin, Mauro, Marchi, Pedro De, Terra, Ricardo Mingarini, Ribeiro, Ronaldo Albuquerque, Lima, Vladmir Cláudio Cordeiro de, Werutsky, Gustavo, Barrios, Carlos Henrique

“…Lung cancer is one of the most incident types of cancer and a leading cause of cancer mortality in Brazil. We reviewed the current status of lung cancer by…”
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Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial by Machiels, Jean-Pascal H, Prof, Haddad, Robert I, MD, Fayette, Jérôme, MD, Licitra, Lisa F, MD, Tahara, Makoto, MD, Vermorken, Jan B, Prof, Clement, Paul M, Prof, Gauler, Thomas, MD, Cupissol, Didier, MD, Grau, Juan José, MD, Guigay, Joël, Prof, Caponigro, Francesco, MD, de Castro, Gilberto, PhD, de Souza Viana, Luciano, MD, Keilholz, Ulrich, Prof, del Campo, Joseph M, MD, Cong, Xiuyu Julie, PhD, Ehrnrooth, Eva, MD, Cohen, Ezra E W, MD

“…Summary Background Patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (HNSCC) progressing after first-line platinum regimens…”
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Five-Year Outcomes With Pembrolizumab Versus Chemotherapy as First-Line Therapy in Patients With Non-Small-Cell Lung Cancer and Programmed Death Ligand-1 Tumor Proportion Score ≥ 1% in the KEYNOTE-042 Study by de Castro, Jr, Gilberto, Kudaba, Iveta, Wu, Yi-Long, Lopes, Gilberto, Kowalski, Dariusz M, Turna, Hande Z, Caglevic, Christian, Zhang, Li, Karaszewska, Boguslawa, Laktionov, Konstantin K, Srimuninnimit, Vichien, Bondarenko, Igor, Kubota, Kaoru, Mukherjee, Rinee, Lin, Jianxin, Souza, Fabricio, Mok, Tony S K, Cho, Byoung Chul

“…JCO We report 5-year results from the phase III KEYNOTE-042 study (ClinicalTrials.gov identifier: NCT02220894). Eligible patients with locally…”
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Pembrolizumab Alone or With Chemotherapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma in KEYNOTE-048: Subgroup Analysis by Programmed Death Ligand-1 Combined Positive Score by Burtness, Barbara, Rischin, Danny, Greil, Richard, Soulières, Denis, Tahara, Makoto, de Castro, Jr, Gilberto, Psyrri, Amanda, Brana, Irene, Basté, Neus, Neupane, Prakash, Bratland, Åse, Fuereder, Thorsten, Hughes, Brett G M, Mesia, Ricard, Ngamphaiboon, Nuttapong, Rordorf, Tamara, Wan Ishak, Wan Zamaniah, Ge, Joy, Swaby, Ramona F, Gumuscu, Burak, Harrington, Kevin

“…The phase III KEYNOTE-048 (ClinicalTrials.gov identifier: NCT02358031) trial of pembrolizumab in recurrent or metastatic (R/M) head and neck squamous cell…”
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Effectiveness and toxicity of adjuvant chemotherapy in patients with non-small cell lung cancer by Harada, Guilherme, Neffa, Maria Fernanda Batistuzzo Vicentini, Bonadio, Renata Colombo, Mendoza, Elizabeth Zambrano, Caparica, Rafael, Lauricella, Letícia Leone, Takagaki, Teresa Yae, Roitberg, Felipe Santa Rosa, Terra, Ricardo Mingarini, Castro, Jr, Gilberto De

“…Adjuvant chemotherapy (AC) improves survival of patients with resected non-small cell lung cancer (NSCLC). However, the cisplatin-vinorelbine regimen has been…”
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Cushing's syndrome due to ectopic adrenocorticotropin secretion by a parotid carcinoma by Antonacio, Fernanda F, Harada, Guilherme, Vilela, Rafael S, Freitas, Thais C, Lima, Jr, Jose V, Kowalski, Luiz Paulo, Almeida, Madson Q, de Castro, Junior, Gilberto

“…We report a rare case of Cushing's syndrome in a 37-year-old female who initially presented with localized acinic cell carcinoma of the parotid gland. In…”
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Locally advanced oral squamous cell carcinoma patients treated with photobiomodulation for prevention of oral mucositis: retrospective outcomes and safety analyses by Brandão, Thaís Bianca, Morais-Faria, Karina, Ribeiro, Ana Carolina Prado, Rivera, César, Salvajoli, João Victor, Lopes, Marcio Ajudarte, Epstein, Joel B., Arany, Praveen R., de Castro, Gilberto, Migliorati, Cesar Augusto, Santos-Silva, Alan Roger

“…Purpose The well-established clinical efficacy of photobiomodulation (PBM) therapy in management of oral mucositis (OM) is leading to increasing use in…”
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Multicenter, randomized, double-blind clinical trial to evaluate efficacy and safety of combined glucosamine sulfate and chondroitin sulfate capsules for treating knee osteoarthritis by Lomonte, Andrea Barranjard Vannucci, Mendonça, José Alexandre, de Castro Brandão, Gilberto, Castro, Marise Lazaretti

“…To compare the efficacy and safety of a new fixed dose combination of glucosamine sulfate and chondroitin sulfate capsules (GS/CS) versus the fixed dose…”
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Outcomes With Pembrolizumab Monotherapy in Patients With Programmed Death-Ligand 1–Positive NSCLC With Brain Metastases: Pooled Analysis of KEYNOTE-001, 010, 024, and 042 by Mansfield, Aaron S., Herbst, Roy S., de Castro, Gilberto, Hui, Rina, Peled, Nir, Kim, Dong-Wan, Novello, Silvia, Satouchi, Miyako, Wu, Yi-Long, Garon, Edward B., Reck, Martin, Robinson, Andrew G., Samkari, Ayman, Piperdi, Bilal, Ebiana, Victoria, Lin, Jianxin, Mok, Tony S.K.

“…We retrospectively evaluated outcomes in patients with programmed death-ligand 1 (PD-L1)–positive NSCLC to determine whether baseline (i.e., at study…”
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Impact of pandemic COVID-19 outbreak on oral mucositis preventive and treatment protocols: new perspectives for extraoral photobiomodulation therapy by Faria, Karina Morais, Gomes-Silva, Wagner, Kauark-Fontes, Elisa, Bonfim-Alves, Carolina Guimarães, Kowalski, Luiz Paulo, Prado-Ribeiro, Ana Carolina, Vechiato-Filho, Aljomar José, Lopes, Marcio Ajudarte, Marta, Gustavo Nader, de Castro, Gilberto, Leme, Adriana Franco Paes, Migliorati, Cesar Augusto, Santos-Silva, Alan Roger, Brandão, Thaís Bianca

“…This communication discusses the current challenges of oral mucositis (OM) management during the pandemic COVID-19 outbreak and reflects about an extraoral…”
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