Search Results - "DE AZEVEDO, M L"

Transcriptome analysis of Loxosceles laeta (Araneae, Sicariidae) spider venomous gland using expressed sequence tags by Fernandes-Pedrosa, Matheus de F, Junqueira-de-Azevedo, Inácio de L M, Gonçalves-de-Andrade, Rute M, Kobashi, Leonardo S, Almeida, Diego D, Ho, Paulo L, Tambourgi, Denise V

“…The bite of spiders belonging to the genus Loxosceles can induce a variety of clinical symptoms, including dermonecrosis, thrombosis, vascular leakage,…”
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Colubrid Venom Composition: An -Omics Perspective by Junqueira-de-Azevedo, Inácio L M, Campos, Pollyanna F, Ching, Ana T C, Mackessy, Stephen P

“…Snake venoms have been subjected to increasingly sensitive analyses for well over 100 years, but most research has been restricted to front-fanged snakes,…”
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The Venom Composition of the Snake Tribe Philodryadini: 'Omic' Techniques Reveal Intergeneric Variability among South American Racers by Tioyama, Emilly Campos, Bayona-Serrano, Juan David, Portes-Junior, José A, Nachtigall, Pedro Gabriel, de Souza, Vinicius Carius, Beraldo-Neto, Emidio, Grazziotin, Felipe Gobbi, Junqueira-de-Azevedo, Inácio L M, Moura-da-Silva, Ana Maria, Freitas-de-Sousa, Luciana Aparecida

“…Snakes of the Philodryadini tribe are included in the Dipsadidae family, which is a diverse group of rear-fanged snakes widespread in different ecological…”
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Profiling the resting venom gland of the scorpion Tityus stigmurus through a transcriptomic survey by Almeida, Diego D, Scortecci, Katia C, Kobashi, Leonardo S, Agnez-Lima, Lucymara F, Medeiros, Silvia R B, Silva-Junior, Arnóbio A, Junqueira-de-Azevedo, Inácio de L M, Fernandes-Pedrosa, Matheus de F

“…The scorpion Tityus stigmurus is widely distributed in Northeastern Brazil and known to cause severe human envenoming, inducing pain, hyposthesia, edema,…”
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Venom Composition of Neglected Bothropoid Snakes from the Amazon Rainforest: Ecological and Toxinological Implications by Freitas-de-Sousa, Luciana A, Colombini, Mônica, Souza, Vinicius C, Silva, Joanderson P C, Mota-da-Silva, Ageane, Almeida, Marllus R N, Machado, Reginaldo A, Fonseca, Wirven L, Sartim, Marco A, Sachett, Jacqueline, Serrano, Solange M T, Junqueira-de-Azevedo, Inácio L M, Grazziotin, Felipe G, Monteiro, Wuelton M, Bernarde, Paulo S, Moura-da-Silva, Ana M

“…Snake venoms have evolved in several families of Caenophidae, and their toxins have been assumed to be biochemical weapons with a role as a trophic adaptation…”
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Lachesis muta (Viperidae) cDNAs Reveal Diverging Pit Viper Molecules and Scaffolds Typical of Cobra (Elapidae) Venoms: Implications for Snake Toxin Repertoire Evolution by Junqueira-de-Azevedo, Inacio L. M, Ching, Ana T. C, Carvalho, Eneas, Faria, Fernanda, Nishiyama, Milton Y., Jr, Ho, Paulo L, Diniz, Marcelo R. V

“…Efforts to describe toxins from the two major families of venomous snakes (Viperidae and Elapidae) usually reveal proteins belonging to few structural types,…”
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Transcripts involved in hemostasis: Exploring salivary complexes from Haementeria vizottoi leeches through transcriptomics, phylogenetic studies and structural features by Amorim, Adriane Michele Xavier Prado, de Oliveira, Ursula Castro, Faria, Fernanda, Pasqualoto, Kerly Fernanda Mesquita, Junqueira-de-Azevedo, Inácio de L.M., Chudzinski-Tavassi, Ana Marisa

“…Throughout evolution, parasites have adapted in order to successfully intervene in the host defense, producing specific peptides and proteins. Interestingly,…”
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A transcriptomic view of the proteome variability of newborn and adult Bothrops jararaca snake venoms by Zelanis, André, Andrade-Silva, Débora, Rocha, Marisa M, Furtado, Maria F, Serrano, Solange M T, Junqueira-de-Azevedo, Inácio L M, Ho, Paulo Lee

“…Snake bite is a neglected public health problem in communities in rural areas of several countries. Bothrops jararaca causes many snake bites in Brazil and…”
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Transcriptomic basis for an antiserum against Micrurus corallinus (coral snake) venom by Leão, Luciana I, Ho, Paulo L, Junqueira-de-Azevedo, Inacio de L M

“…Micrurus corallinus (coral snake) is a tropical forest snake belonging to the family Elapidae. Its venom shows a high neurotoxicity associated with pre- and…”
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Bothrops jararaca venom gland transcriptome: Analysis of the gene expression pattern by Cidade, Daniela A.P., Simão, Tatiana A., Dávila, Alberto M.R., Wagner, Glauber, de L.M. Junqueira-de-Azevedo, Inácio, Lee Ho, Paulo, Bon, Cassian, Zingali, Russolina B., Albano, Rodolpho M.

“…Bothrops jararaca is a pit viper responsible for the majority of snake envenoming accidents in Brazil. As an attempt to describe the transcriptional activity…”
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Novel transcripts in the maxillary venom glands of advanced snakes by Fry, Bryan G., Scheib, Holger, Junqueira de Azevedo, Inacio de L.M., Silva, Debora Andrade, Casewell, Nicholas R.

“…Venom proteins are added to reptile venoms through duplication of a body protein gene, with the duplicate tissue-specifically expressed in the venom gland…”
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A New Anti-loxoscelic Serum Produced Against Recombinant Sphingomyelinase D: Results of Preclinical Trials by de Almeida, Daniel Manzoni, Fernandes-Pedrosa, Matheus de F, de Andrade, Rute M. Goncalves, Marcelino, Jose Roberto, Gondo-Higashi, Hisako, de Azevedo, Inacio de L. M. Junqueira, Ho, Paulo Lee, van den Berg, Carmen, Tambourgi, Denise V

“…Envenomation by Loxosceles species (brown spider) can lead to local dermonecrosis and to serious systemic effects. The main toxic component in the venom of…”
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Proteomic and Glycoproteomic Profilings Reveal That Post-translational Modifications of Toxins Contribute to Venom Phenotype in Snakes by Andrade-Silva, Débora, Zelanis, André, Kitano, Eduardo S, Junqueira-de-Azevedo, Inácio L. M, Reis, Marcelo S, Lopes, Aline S, Serrano, Solange M. T

“…Snake venoms are biological weapon systems composed of secreted proteins and peptides that are used for immobilizing or killing prey. Although…”
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Differences in PLA2 Constitution Distinguish the Venom of Two Endemic Brazilian Mountain Lanceheads, Bothrops cotiara and Bothrops fonsecai by Nachtigall, Pedro G., Freitas-de-Sousa, Luciana A., Mason, Andrew J., Moura-da-Silva, Ana M., Grazziotin, Felipe G., Junqueira-de-Azevedo, Inácio L. M.

“…Interspecific differences in snake venom compositions can result from distinct regulatory mechanisms acting in each species. However, comparative analyses…”
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Size Matters: An Evaluation of the Molecular Basis of Ontogenetic Modifications in the Composition of Bothrops jararacussu Snake Venom by Freitas-de-Sousa, Luciana A, Nachtigall, Pedro G, Portes-Junior, José A, Holding, Matthew L, Nystrom, Gunnar S, Ellsworth, Schyler A, Guimarães, Noranathan C, Tioyama, Emilly, Ortiz, Flora, Silva, Bruno R, Kunz, Tobias S, Junqueira-de-Azevedo, Inácio L M, Grazziotin, Felipe G, Rokyta, Darin R, Moura-da-Silva, Ana M

“…Ontogenetic changes in venom composition have been described in snakes, but only a few studies have attempted to identify the targeted paralogues or the…”
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Snake venomics and venom gland transcriptomic analysis of Brazilian coral snakes, Micrurus altirostris and M. corallinus by Corrêa-Netto, Carlos, Junqueira-de-Azevedo, Inácio de L.M., Silva, Débora A., Ho, Paulo L., Leitão-de-Araújo, Moema, Alves, Maria Lúcia M., Sanz, Libia, Foguel, Débora, Zingali, Russolina Benedeta, Calvete, Juan J.

“…The venom proteomes of Micrurus altirostris and M. corallinus were analyzed by combining snake venomics and venom gland transcriptomic surveys. In both coral…”
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Venomics Profiling of Thamnodynastes strigatus Unveils Matrix Metalloproteinases and Other Novel Proteins Recruited to the Toxin Arsenal of Rear-Fanged Snakes by Ching, Ana T. C, Paes Leme, Adriana F, Zelanis, André, Rocha, Marisa M. T, Furtado, Maria de Fátima D, Silva, Débora Andrade, Trugilho, Monique R. O, da Rocha, Surza L. G, Perales, Jonas, Ho, Paulo L, Serrano, Solange M. T, Junqueira-de-Azevedo, Inácio L. M

“…Rear-fanged and aglyphous snakes are usually considered not dangerous to humans because of their limited capacity of injecting venom. Therefore, only a few…”
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Phylogenetically diverse diets favor more complex venoms in North American pitvipers by Holding, Matthew L., Strickland, Jason L., Rautsaw, Rhett M., Hofmann, Erich P., Mason, Andrew J., Hogan, Michael P., Nystrom, Gunnar S., Ellsworth, Schyler A., Colston, Timothy J., Borja, Miguel, Castan˜eda-Gaytán, Gamaliel, Grünwald, Christoph I., Jones, Jason M., Freitas-de-Sousa, Luciana A., Viala, Vincent Louis, Margres, Mark J., Hingst-Zaher, Erika, Junqueira-de-Azevedo, Inácio L. M., Moura-da-Silva, Ana M., Grazziotin, Felipe G., Gibbs, H. Lisle, Rokyta, Darin R., Parkinson, Christopher L.

“…The role of natural selection in the evolution of trait complexity can be characterized by testing hypothesized links between complex forms and their functions…”
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Tracking the recruitment and evolution of snake toxins using the evolutionary context provided by the Bothrops jararaca genome by Almeida, Diego Dantas, Viala, Vincent Louis, Nachtigall, Pedro Gabriel, Broe, Michael, Gibbs, H. Lisle, de Toledo Serrano, Solange Maria, Moura-da-Silva, Ana Maria, Ho, Paulo Lee, Nishiyama, Milton Yutaka, Junqueira-de-Azevedo, Inácio L. M.

“…Venom is a key adaptive innovation in snakes, and how nonvenom genes were co-opted to become part of the toxin arsenal is a significant evolutionary question…”
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SMase II, a new sphingomyelinase D from Loxosceles laeta venom gland: Molecular cloning, expression, function and structural analysis by de Santi Ferrara, Guilherme I., Fernandes-Pedrosa, Matheus de F., Junqueira-de-Azevedo, Inácio de L.M., Gonçalves-de-Andrade, Rute M., Portaro, Fernanda C.V., Manzoni-de-Almeida, Daniel, Murakami, Mário T., Arni, Raghuvir K., van den Berg, Carmen W., Ho, Paulo L., Tambourgi, Denise V.

“…Sphingomyelinase D (SMase D) present in the venoms of Loxosceles spiders is the principal component responsible for local and systemic effects observed in the…”
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