Search Results - "DE ARAUJO, WALLACE MARTINS"
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Crosstalk between PI3K/Akt and Wnt/β-catenin pathways promote colorectal cancer progression regardless of mutational status
Published in Cancer biology & therapy (31-12-2022)“…The PI3K/Akt and Wnt/β-catenin pathways play an important role in the acquisition of the malignant phenotype in cancer. However, there are few data regarding…”
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Inhibition of N-linked glycosylation by tunicamycin induces E-cadherin-mediated cell–cell adhesion and inhibits cell proliferation in undifferentiated human colon cancer cells
Published in Cancer chemotherapy and pharmacology (01-07-2011)“…Purpose Aberrant protein glycosylation and disassembly of E-cadherin-mediated cell–cell adhesion are characteristics of epithelial cancer. However, the…”
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3
PI3K/Akt and GSK-3β prevents in a differential fashion the malignant phenotype of colorectal cancer cells
Published in Journal of cancer research and clinical oncology (01-11-2010)“…Purpose During colorectal cancer progression, the loss of differentiation and cell-cell adhesion as well as a higher migratory potential are well-defined…”
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4
Docosahexaenoic acid promotes cell cycle arrest and decreases proliferation through WNT/β‐catenin modulation in colorectal cancer cells exposed to γ‐radiation
Published in BioFactors (Oxford) (01-01-2019)“…The effects of radiation are known to be potentiated by N‐3 polyunsaturated fatty acids, which modulate several signaling pathways, but the molecular…”
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PTEN Overexpression Cooperates With Lithium to Reduce the Malignancy and to Increase Cell Death by Apoptosis via PI3K/Akt Suppression in Colorectal Cancer Cells
Published in Journal of cellular biochemistry (01-02-2016)“…ABSTRACT Lithium is a well‐established non‐competitive inhibitor of glycogen synthase kinase‐3β (GSK‐3β), a kinase that is involved in several cellular…”
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Progeny From Irradiated Colorectal Cancer Cells Acquire an EMT-Like Phenotype and Activate Wnt/β-Catenin Pathway
Published in Journal of cellular biochemistry (01-12-2014)“…ABSTRACT Radiotherapy remains a major approach to adjuvant therapy for patients with advanced colorectal cancer, however, the fractionation schedules…”
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PTEN Overexpression Cooperates With Lithium to Reduce the Malignancy and to Increase Cell Death by Apoptosis via PI3K/Akt Suppression in Colorectal Cancer Cells: PTEN C OOPERATES W ITH L ITHIUM T o I NCREASE C ELL D EATH
Published in Journal of cellular biochemistry (01-02-2016)Get full text
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Ouabain-Induced Alterations of the Apical Junctional Complex Involve α1 and β1 Na,K-ATPase Downregulation and ERK1/2 Activation Independent of Caveolae in Colorectal Cancer Cells
Published in The Journal of membrane biology (2014)“…Studies have reported that Na,K-ATPase interacts with E-cadherin to stabilize (AJs) and regulate the expression of claudins, the main proteins present in the…”
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9
Progeny From Irradiated Colorectal Cancer Cells Acquire an EMT-Like Phenotype and Activate Wnt/[beta]-Catenin Pathway
Published in Journal of cellular biochemistry (01-12-2014)“…Radiotherapy remains a major approach to adjuvant therapy for patients with advanced colorectal cancer, however, the fractionation schedules frequently allow…”
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Journal Article -
10
Lithium reduces tumorigenic potential in response to EGF signaling in human colorectal cancer cells
Published in International journal of oncology (01-05-2011)“…Lithium is a specific inhibitor of GSK3-β, and hence, an activator of the Wnt/β-catenin pathway, whereas the epidermal growth factor (EGF) has been linked to…”
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11
Ouabain-Induced Alterations of the Apical Junctional Complex Involve [alpha]1 and [beta]1 Na,K-ATPase Downregulation and ERK1/2 Activation Independent of Caveolae in Colorectal Cancer Cells
Published in The Journal of membrane biology (01-01-2014)“…Studies have reported that Na,K-ATPase interacts with E-cadherin to stabilize (AJ) and regulate the expression of claudins, the main proteins present in the…”
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Journal Article -
12
Blockade of irradiation-induced autophagosome formation impairs proliferation but does not enhance cell death in HCT-116 human colorectal carcinoma cells
Published in International journal of oncology (01-04-2012)“…This work was undertaken to gain further information on the molecular mechanisms underlying autophagosome formation and its relation with tumor cell survival…”
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13
PI3K/Akt and GSK-3[beta] prevents in a differential fashion the malignant phenotype of colorectal cancer cells
Published in Journal of cancer research and clinical oncology (01-11-2010)“…During colorectal cancer progression, the loss of differentiation and cell-cell adhesion as well as a higher migratory potential are well-defined features;…”
Get full text
Journal Article