Search Results - "DAZA, A. V"

In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB2 receptor? by Yao, B B, Mukherjee, S, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Hooker, B A, Dart, M J, Sullivan, J P, Meyer, M D

“…Background and purpose: The CB2 receptor has been proposed as a novel target for the treatment of pain, and CB2 receptor agonists defined in in vitro assays…”
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In vitro and in vivo characterization of A‐796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models by Yao, B B, Hsieh, G C, Frost, J M, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Zhu, C Z, Pai, M, Chandran, P, Salyers, A K, Wensink, E J, Honore, P, Sullivan, J P, Dart, M J, Meyer, M D

“…Background and purpose: Selective cannabinoid CB2 receptor agonists have demonstrated analgesic activity across multiple preclinical pain models. AM1241 is an…”
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Peripheral and central sites of action for the non‐selective cannabinoid agonist WIN 55,212‐2 in a rat model of post‐operative pain by Zhu, CZ, Mikusa, JP, Fan, Y, Hollingsworth, PR, Pai, M, Chandran, P, Daza, AV, Yao, BB, Dart, MJ, Meyer, MD, Decker, MW, Hsieh, GC, Honore, P

“…Background and purpose:  Activation of cannabinoid (CB) receptors decreases nociceptive transmission in inflammatory or neuropathic pain states. However, the…”
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In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB 2 receptor? by Yao, B B, Mukherjee, S, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Hooker, B A, Dart, M J, Sullivan, J P, Meyer, M D

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In vitro and in vivo characterization of A‐796260: a selective cannabinoid CB 2 receptor agonist exhibiting analgesic activity in rodent pain models by Yao, B B, Hsieh, G C, Frost, J M, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Zhu, C Z, Pai, M, Chandran, P, Salyers, A K, Wensink, E J, Honore, P, Sullivan, J P, Dart, M J, Meyer, M D

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Bronchial and alveolar allergen-induced anaphylaxis and the stimulation of bronchial mucociliary clearance in ragweed-sensitized dogs by Yeates, D B, Daza, A V, Mussatto, D J

“…In allergic airways disease, we hypothesized that an acute allergen inhalation activates cells in the bronchial and alveolar regions of the lungs to initiate…”
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(-)-(9S)-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide (A-278637): a novel ATP-sensitive potassium channel opener efficacious in suppressing urinary bladder contractions. I. In vitro characterization by Gopalakrishnan, Murali, Buckner, Steven A, Whiteaker, Kristi L, Shieh, Char-Chang, Molinari, Eduardo J, Milicic, Ivan, Daza, Anthony V, Davis-Taber, Rachel, Scott, Victoria E, Sellers, Donna, Chess-Williams, Russ, Chapple, Christopher R, Liu, Yi, Liu, Dong, Brioni, Jorge D, Sullivan, James P, Williams, Michael, Carroll, William A, Coghlan, Michael J

“…Alterations in the myogenic activity of the bladder smooth muscle are thought to serve as a basis for the involuntary detrusor contractions associated with the…”
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In vitro and in vivo characterization of A-796260: a selective cannabinoid CB sub(2) receptor agonist exhibiting analgesic activity in rodent pain models by Yao, B B, Hsieh, G C, Frost, J M, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Zhu, C Z, Pai, M, Chandran, P, Salyers, A K, Wensink, E J, Honore, P, Sullivan, J P

“…Background and purpose: Selective cannabinoid CB sub(2) receptor agonists have demonstrated analgesic activity across multiple preclinical pain models. AMI 241…”
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In vitro and in vivo characterization of A-796260 : a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models: CB2 cannabinoid receptors by YAO, B. B, HSIEH, G. C, SALYERS, A. K, WENSINK, E. J, HONORE, P, SULLIVAN, J. P, DART, M. J, MEYER, M. D, FROST, J. M, FAN, Y, GARRISON, T. R, DAZA, A. V, GRAYSON, G. K, ZHU, C. Z, PAI, M, CHANDRAN, P

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In vitro pharmacological characterization of AM1241: a protean agonist at the cannabinoid CB sub(2) receptor? by Yao, B B, Mukherjee, S, Fan, Y, Garrison, T R, Daza, A V, Grayson, G K, Hooker, BA, Dart, MJ, Sullivan, J P, Meyer, MD

“…Background and purpose: The CB sub(2) receptor has been proposed as a novel target for the treatment of pain, and CB sub(2) receptor agonists defined in in…”
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Spontaneous phasic activity of the pig urinary bladder smooth muscle: characteristics and sensitivity to potassium channel modulators by Buckner, Steven A, Milicic, Ivan, Daza, Anthony V, Coghlan, Michael J, Gopalakrishnan, Murali

“…A hallmark for unstable bladder contractions is hyperexcitability and changes in the nature of spontaneous phasic activity of the bladder smooth muscle. In…”
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Pharmacological properties of A-204176, a novel and selective alpha1A adrenergic agonist, in in vitro and in vivo models of urethral function by O'Neill, A B, Buckner, S A, Brune, M E, Milicic, I, Daza, A V, Gauvin, D M, Altenbach, R J, Meyer, M D, Williams, M, Sullivan, J P, Brioni, J D

“…A-204176 (N-[5-(1H-imidazol-4-y1)-5,6,7,8-tetrahydro-1-naphthalenyl]methanesulfonamide) is a potent and selective alpha1A adrenoceptor agonist that binds with…”
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Functional characterization of large conductance calcium-activated K+ channel openers in bladder and vascular smooth muscle by Malysz, John, Buckner, Steven A, Daza, Anthony V, Milicic, Ivan, Perez-Medrano, Arturo, Gopalakrishnan, Murali

“…Calcium activated K(+) channels (K(Ca) channels) are found in a variety of smooth muscle tissues, the most characterized of which are the large conductance…”
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Synthesis and Structure−Activity Relationships of a Novel Series of 2,3,5,6,7,9-Hexahydrothieno[3,2- b ]quinolin-8(4 H )-one 1,1-Dioxide K ATP Channel Openers:  Discovery of (−)-(9 S )-9-(3-Bromo-4-fluorophenyl)-2,3,5,6,7,9- hexahydrothieno[3,2- b ]quinolin-8(4 H )-one 1,1-Dioxide (A-278637), a Potent K ATP Opener That Selectively Inhibits Spontaneous Bladder Contractions by Carroll, William A., Altenbach, Robert J., Bai, Hao, Brioni, Jorge D., Brune, Michael E., Buckner, Steven A., Cassidy, Christopher, Chen, Yiyuan, Coghlan, Michael J., Daza, Anthony V., Drizin, Irene, Fey, Thomas A., Fitzgerald, Michael, Gopalakrishnan, Murali, Gregg, Robert J., Henry, Rodger F., Holladay, Mark W., King, Linda L., Kort, Michael E., Kym, Philip R., Milicic, Ivan, Tang, Rui, Turner, Sean C., Whiteaker, Kristi L., Yi, Lin, Zhang, Henry, Sullivan, James P.

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Synthesis and Structure−Activity Relationships of a Novel Series of Tricyclic Dihydropyridine-Based K ATP Openers That Potently Inhibit Bladder Contractions in Vitro by Carroll, William A., Agrios, Konstantinos A., Altenbach, Robert J., Buckner, Steven A., Chen, Yiyuan, Coghlan, Michael J., Daza, Anthony V., Drizin, Irene, Gopalakrishnan, Murali, Henry, Rodger F., Kort, Michael E., Kym, Philip R., Milicic, Ivan, Smith, Jamie C., Tang, Rui, Turner, Sean C., Whiteaker, Kristi L., Zhang, Henry, Sullivan, James P.

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In vitro and in vivo characterization of a novel naphthylamide ATP‐sensitive K+ channel opener, A‐151892 by Gopalakrishnan, Murali, Buckner, Steven A, Shieh, Char‐Chang, Fey, Thomas, Fabiyi, Adebola, Whiteaker, Kristi L, Davis‐Taber, Rachel, Milicic, Ivan, Daza, Anthony V, Scott, Victoria E S, Castle, Neil A, Printzenhoff, David, London, Brecht, Turner, Sean C, Carroll, William A, Sullivan, James P, Coghlan, Michael J, Brune, Michael E

“…Openers of ATP‐sensitive K+ channels are of interest in several therapeutic indications including overactive bladder and other lower urinary tract disorders…”
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ABT-866, a novel alpha(1A)-adrenoceptor agonist with antagonist properties at the alpha(1B)- and alpha(1D)-adrenoceptor subtypes by Buckner, Steven A, Milicic, Ivan, Daza, Anthony V, Meyer, Michael D, Altenbach, Robert J, Williams, Michael, Sullivan, James P, Brioni, Jorge D

“…N-[3-(1H-Imidazol-4-ylmethyl)phenyl]ethanesulfonamide, maleate (ABT-866) is a novel alpha(1)-adrenoceptor agent with mixed pharmacological properties in vitro…”
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Synthesis and structure-activity studies on N-[5-(1H-imidazol-4-yl)-5,6,7,8-tetrahydro-1-naphthalenyl]methanesulfonamide, an imidazole-containing alpha(1A)-adrenoceptor agonist by Altenbach, Robert J, Khilevich, Albert, Kolasa, Teodozyj, Rohde, Jeffrey J, Bhatia, Pramila A, Patel, Meena V, Searle, Xenia B, Yang, Fan, Bunnelle, William H, Tietje, Karin, Bayburt, Erol K, Carroll, William A, Meyer, Michael D, Henry, Rodger, Buckner, Steven A, Kuk, Jane, Daza, Anthony V, Milicic, Ivan V, Cain, John C, Kang, Chae H, Ireland, Lynne M, Carr, Tracy L, Miller, Thomas R, Hancock, Arthur A, Nakane, Masaki, Esbenshade, Timothy A, Brune, Michael E, O'Neill, Alyssa B, Gauvin, Donna M, Katwala, Sweta P, Holladay, Mark W, Brioni, Jorge D, Sullivan, James P

“…Structure-activity studies were performed on the alpha(1A)-adrenoceptor (AR) selective agonist…”
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N-[3-(1H-imidazol-4-ylmethyl)phenyl]ethanesulfonamide (ABT-866, 1),(1) a novel alpha(1)-adrenoceptor ligand with an enhanced in vitro and in vivo profile relative to phenylpropanolamine and midodrine by Altenbach, Robert J, Khilevich, Albert, Meyer, Michael D, Buckner, Steven A, Milicic, Ivan, Daza, Anthony V, Brune, Michael E, O'Neill, Alyssa B, Gauvin, Donna M, Cain, John C, Nakane, Masaki, Holladay, Mark W, Williams, Michael, Brioni, Jorge D, Sullivan, James P

“…N-[3-(1H-Imidazol-4-ylmethyl)phenyl]ethanesulfonamide (ABT-866, 1) is a novel alpha(1) agent having the unique profile of alpha(1A) (rabbit urethra, EC(50) =…”
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Excitatory and Inhibitory Neural Regulation of Tracheal Ciliary Beat Frequency (CBF) Activated by Ammonia Vapour and SO2 by Yeates, D. B., Katwala, S. P., Daugird, J., Daza, A. V., Wong, L. B.

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