Search Results - "DAYANANDAN, R"

Exploring the Relationship Between Youth Participation in Community Development and Positive Youth Development in Hadiya Zone, Ethiopia: A CB-SEM Analysis by Jekamo, Gizachew B., R., Dayanandan, Nuri, Tofik M.

Get full text

Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease by Sammons, E, Hopewell, J C, Chen, F, Stevens, W, Wallendszus, K, Valdes-Marquez, E, Dayanandan, R, Knott, C, Murphy, K, Wincott, E, Baxter, A, Goodenough, R, Lay, M, Hill, M, Macdonnell, S, Fabbri, G, Lucci, D, Fajardo-Moser, M, Brenner, S, Hao, D, Zhang, H, Liu, J, Wuhan, B, Mosegaard, S, Herrington, W, Wanner, C, Angermann, C, Ertl, G, Maggioni, A, Barter, P, Mihaylova, B, Mitchel, Y, Blaustein, R, Goto, S, Tobert, J, DeLucca, P, Chen, Y, Chen, Z, Gray, A, Haynes, R, Armitage, J, Baigent, C, Wiviott, S, Cannon, C, Braunwald, E, Collins, R, Bowman, L, Landray, M

“…Abstract Aims REVEAL was the first randomized controlled trial to demonstrate that adding cholesteryl ester transfer protein inhibitor therapy to intensive…”
Get full text

Paroxysmal dysarthria ataxia syndrome responds to lacosamide by Lilleker, JB, Gall, C, Dayanandan, R, Chhetri, SK, Emsley, HCA

Get full text

Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation by Dayanandan, R., Van Slegtenhorst, M., Mack, T.G.A., Ko, L., Yen, S.-H., Leroy, K., Brion, J.-P., Anderton, B.H., Hutton, M., Lovestone, S.

“…In vitro evidence has suggested a change in the ability of tau bearing mutations associated with fronto-temporal dementia to promote microtubule assembly. We…”
Get full text

Screening for problem drinking in older people referred to a mental health service: A comparison of CAGE and AUDIT by Philpot, M., Pearson, N., Petratou, V., Dayanandan, R., Silverman, M., Marshall, J.

“…The aim of the study was to evaluate the validity of the Alcohol Use Disorders Identification Test (AUDIT), the five-item version (AUDIT-5) and the CAGE as…”
Get full text

Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3β inhibition and in neurons by FORLENZA, O. V, SPINK, J. M, DAYANANDAN, R, ANDERTON, B. H, OLESEN, O. F, LOVESTONE, S

“…Muscarinic agonists alter the metabolism of amyloid precursor protein, leading to an increase in alpha -secretase cleavage and a decreased production of…”
Get full text

Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease by Bowman, Louise, Hopewell, Jemma C, Chen, Fang, Wallendszus, Karl, Stevens, William, Collins, Rory, Wiviott, Stephen D, Cannon, Christopher P, Braunwald, Eugene, Sammons, Emily, Landray, Martin J

“…In this trial involving patients with atherosclerotic disease who were receiving effective statin therapy, those who were assigned to receive anacetrapib, a…”
Get full text

Tau proteins with frontotemporal dementia-17 mutations have both altered expression levels and phosphorylation profiles in differentiated neuroblastoma cells by Mack, T.G.A, Dayanandan, R, Van Slegtenhorst, M, Whone, A, Hutton, M, Lovestone, S, Anderton, B.H

“…The inherited form of frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17) has been attributed to mutations in the tau gene…”
Get full text

The function of the microtubule-associated protein tau is variably modulated by graded changes in glycogen synthase kinase-3β activity by Leroy, K., Menu, R., Conreur, J.L., Dayanandan, R., Lovestone, S., Anderton, B.H., Brion, J.P.

“…The microtubule-associated protein tau favors microtubule nucleation and stabilization and plays a role in the elongation of axons. We have investigated the…”
Get full text

Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12 064 survivors of myocardial infarction: a double-blind randomised trial by Armitage, Jane, Bowman, Louise, Wallendszus, Karl, Bulbulia, Richard, Rahimi, Kazem, Haynes, Richard, Parish, Sarah, Peto, Richard, Collins, Rory

“…Summary Background Lowering of LDL cholesterol reduces major vascular events, but whether more intensive therapy safely produces extra benefits is uncertain…”
Get full text

Randomized multicentre pilot study of sacubitril/valsartan versus irbesartan in patients with chronic kidney disease: United Kingdom Heart and Renal Protection (HARP)- III-rationale, trial design and baseline data

“…Patients with chronic kidney disease (CKD) are at risk of progression to end-stage renal disease and cardiovascular disease. Data from other populations and…”
Get full text

Apolipoprotein E (apoE) uptake and distribution in mammalian cell lines is dependent upon source of apoE and can be monitored in living cells by Ljungberg, M.C, Asuni, A, Pearce, J, Dayanandan, R, März, W, Hoffmann, M.M, Bertrand, P, Siest, G, Rupniak, H.T.R, Anderton, B.H, Huettinger, M, Lovestone, S

“…As part of investigations of the cellular uptake of apolipoprotein E (apoE) relevant to Alzheimer's disease we have found that different preparations of apoE…”
Get full text

089 Delayed primary CNS post-transplant lymphoproliferative disorder (PTLD): Abstract 089 Figure 1 by Chhetri, S K, Dayanandan, R, Joseph, J, Armour, A, Sonwalkar, H, Emsley, H C A

Get full text

089 Delayed primary CNS post-transplant lymphoproliferative disorder (PTLD) by Chhetri, S K, Dayanandan, R, Joseph, J, Armour, A, Sonwalkar, H, Emsley, H C A

“…Primary central nervous system (PCNS) PTLD is a very rare complication that occurs as a result of immunosuppression in the setting of solid organ…”
Get full text

Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer’s disease? by Anderton, Brian H, Dayanandan, Rejith, Killick, Richard, Lovestone, Simon

“…Alzheimer’s disease is characterized by the presence of neurofibrillary tangles and senile neuritic plaques in the brain. Tangles are aggregates of paired…”
Get full text

Studies on RDX Particle Size in LOVA Gun Propellant Formulations by Pillai, A. G. S., Sanghavi, R. R., Dayanandan, C. R., Joshi, M. M., Velapure, S. P., Singh, Amarjit

“…This paper presents the results of systematic studies carried out on the role of fine RDX in determining the burning rate and ballistics of LOVA gun…”
Get full text

Truncated apoE forms tangle-like structures in a neuronal cell line by Ljungberg, M Cecilia, Dayanandan, Rejith, Asuni, Ayodeji, Rupniak, Tom H, Anderton, Brian H, Lovestone, Simon

“…Apolipoprotein E is the predominant brain lipoprotein and polymorphic variation in the APOE gene the major genetic susceptibly factor for late onset…”
Get full text

Neurofibrillary tangles and tau phosphorylation by Brion, J P, Anderton, B H, Authelet, M, Dayanandan, R, Leroy, K, Lovestone, S, Octave, J N, Pradier, L, Touchet, N, Tremp, G

“…Neurofibrillary tangles (NFTs) are a characteristic neuropathological lesion of Alzheimer's disease (AD). They are composed of a highly-phosphorylated form of…”
Get more information

Sites of phosphorylation in tau and factors affecting their regulation by Anderton, B H, Betts, J, Blackstock, W P, Brion, J P, Chapman, S, Connell, J, Dayanandan, R, Gallo, J M, Gibb, G, Hanger, D P, Hutton, M, Kardalinou, E, Leroy, K, Lovestone, S, Mack, T, Reynolds, C H, Van Slegtenhorst, M

“…The microtubule-associated protein, tau, is the principal component of paired helical filaments (PHFs) in Alzheimer's disease. PHF-tau is highly phosphorylated…”
Get more information

The function of the microtubule-associated protein tau is variably modulated by graded changes in glycogen synthase kinase-3beta activity by Leroy, K, Menu, R, Conreur, J L, Dayanandan, R, Lovestone, S, Anderton, B H, Brion, J P

“…The microtubule-associated protein tau favors microtubule nucleation and stabilization and plays a role in the elongation of axons. We have investigated the…”
Get full text