Search Results - "DAY, Craig W"

Synthesis and Biological Evaluation of Epidithio‑, Epitetrathio‑, and bis-(Methylthio)diketopiperazines: Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8′-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E, and Haematocin and Discovery of New Antiviral and Antimalarial Agents by Nicolaou, K. C, Lu, Min, Totokotsopoulos, Sotirios, Heretsch, Philipp, Giguère, Denis, Sun, Ya-Ping, Sarlah, David, Nguyen, Thu H, Wolf, Ian C, Smee, Donald F, Day, Craig W, Bopp, Selina, Winzeler, Elizabeth A

“…An improved sulfenylation method for the preparation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines from diketopiperazines has been…”
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Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza by London, Nyall R, Zhu, Weiquan, Bozza, Fernando A, Smith, Matthew C P, Greif, Daniel M, Sorensen, Lise K, Chen, Luming, Kaminoh, Yuuki, Chan, Aubrey C, Passi, Samuel F, Day, Craig W, Barnard, Dale L, Zimmerman, Guy A, Krasnow, Mark A, Li, Dean Y

“…The innate immune system provides a first line of defense against invading pathogens by releasing multiple inflammatory cytokines, such as interleukin-1beta…”
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A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo by Day, Craig W, Baric, Ralph, Cai, Sui Xiong, Frieman, Matt, Kumaki, Yohichi, Morrey, John D, Smee, Donald F, Barnard, Dale L

“…Abstract Severe acute respiratory syndrome (SARS) is a highly lethal emerging disease caused by coronavirus SARS-CoV. New lethal animal models for SARS were…”
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Efficacy of Orally Administered T-705 on Lethal Avian Influenza A (H5N1) Virus Infections in Mice by SIDWELL, Robert W, BARNARD, Dale L, DAY, Craig W, SMEE, Donald F, BAILEY, Kevin W, WONG, Min-Hui, MORREY, John D, FURUTA, Yousuke

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Evaluation of Immunomodulators, Interferons and Known in Vitro SARS-CoV Inhibitors for Inhibition of SARS-Cov Replication in BALB/c Mice by Barnard, Dale L, Day, Craig W, Bailey, Kevin, Heiner, Matthew, Montgomery, Robert, Lauridsen, Larry, Chan, Paul KS, Sidwell, Robert W

“…Compounds approved for therapeutic use and in vitro inhibitors of severe acute respiratory syndrome coronavirus (SARS-CoV) were evaluated for inhibition in the…”
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The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice by Warfield, Kelly L, Barnard, Dale L, Enterlein, Sven G, Smee, Donald F, Khaliq, Mansoora, Sampath, Aruna, Callahan, Michael V, Ramstedt, Urban, Day, Craig W

“…Iminosugars that are competitive inhibitors of endoplasmic reticulum (ER) α-glucosidases have been demonstrated to have antiviral activity against a diverse…”
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Isolation and identification of compounds from Kalanchoe pinnata having human alphaherpesvirus and vaccinia virus antiviral activity by Cryer, Matthew, Lane, Kyle, Greer, Mary, Cates, Rex, Burt, Scott, Andrus, Merritt, Zou, Jiping, Rogers, Paul, Hansen, Marc D. H., Burgado, Jillybeth, Satheshkumar, Panayampalli Subbian, Day, Craig W., Smee, Donald F., Johnson, F. Brent

“…Context: Kalanchoe pinnata (Lam.) Pers. (Crassulaceae) is a succulent plant that is known for its traditional antivirus and antibacterial usage. Objective:…”
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Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin by Barnard, Dale L., Day, Craig W., Bailey, Kevin, Heiner, Matthew, Montgomery, Robert, Lauridsen, Larry, Winslow, Scott, Hoopes, Justin, Li, Joseph K.-K., Lee, Jongdae, Carson, Dennis A., Cottam, Howard B., Sidwell, Robert W.

“…Because of the conflicting data concerning the SARS-CoV inhibitory efficacy of ribavirin, an inosine monophosphate (IMP) dehydrogenase inhibitor, studies were…”
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Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones by Havrylyuk, Dmytro, Zimenkovsky, Borys, Vasylenko, Olexandr, Day, Craig W., Smee, Donald F., Grellier, Philippe, Lesyk, Roman

“…A series of novel 5-pyrazoline substituted 4-thiazolidinones have been synthesized. Target compounds were evaluated for their anticancer activity in vitro…”
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(−)-Carbodine: Enantiomeric synthesis and in vitro antiviral activity against various strains of influenza virus including H5N1 (avian influenza) and novel 2009 H1N1 (swine flu) by Rao, Jagadeeshwar R., Jha, Ashok K., Rawal, Ravindra K., Sharon, Ashoke, Day, Craig W., Barnard, Dale L., Smee, Donald F., Chu, Chung K.

“…Enantiomerically pure cyclopentyl cytosine [( −)-carbodine] exhibited potent antiviral activity against H5N1 (avian) and novel H1N1 (swine) flu…”
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Evaluation of cell viability dyes in antiviral assays with RNA viruses that exhibit different cytopathogenic properties by Smee, Donald F., Hurst, Brett L., Evans, W. Joseph, Clyde, Nathan, Wright, Sean, Peterson, Christopher, Jung, Kie-Hoon, Day, Craig W.

“…•Nine antiviral compounds were evaluated against chikungunya, dengue and Junin viruses using different dye indicators.•AlamarBlue, neutral red, Viral ToxGlo…”
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Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus 87 strains to various antiviral compounds by Smee, Donald F, Evans, W Joseph, Nicolaou, K C, Tarbet, E Bart, Day, Craig W

“…Compounds were evaluated for antiviral activity in rhabdomyosarcoma (RD) cells against a recent 2014 clinical isolate of enterovirus D68 (EV-D68), a 1962…”
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Development of a respiratory disease model for enterovirus D68 in 4-week-old mice for evaluation of antiviral therapies by Evans, W. Joseph, Hurst, Brett L., Peterson, Christopher J., Van Wettere, Arnaud J., Day, Craig W., Smee, Donald F., Tarbet, E. Bart

“…Enterovirus D68 (EV-D68) is a non-polio enterovirus that affects the respiratory system and can cause serious complications, especially in children and older…”
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Antivirally Active Ribavirin Analogues – 4,5-disubstituted 1,2,3-triazole Nucleosides: Biological Evaluation against Certain Respiratory Viruses and Computational Modelling by Krajczyk, Anna, Kulinska, Katarzyna, Kulinski, Tadeusz, Hurst, Brett L, Day, Craig W, Smee, Donald F, Ostrowski, Tomasz, Januszczyk, Piotr, Zeidler, Joanna

“…Background: Ribavirin is a broad-spectrum antiviral agent that derives some of its activity from inhibition of cellular inosine monophosphate dehydrogenase…”
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A new oxygen modification cyclooctaoxygen binds to nucleic acids as sodium crown complex by Kesel, Andreas J., Day, Craig W., Montero, Catherine M., Schinazi, Raymond F.

“…Oxygen exists in two gaseous and six solid allotropic modifications. An additional allotropic modification of oxygen, the cyclooctaoxygen, was predicted to…”
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In vitro and in vivo efficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1, seasonal, and pandemic H1N1 virus infections by Kumaki, Yohichi, Day, Craig W., Smee, Donald F., Morrey, John D., Barnard, Dale L.

“…► 2′-Deoxy-2′-fluorocytidine potently inhibited H5N1 influenza viruses. ► 2′-FdC protected H5N1 influenza-virus infected BALB/c mice from death. ► 2′-FdC was…”
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D282, a Non-Nucleoside Inhibitor of Influenza Virus Infection that Interferes with de novo Pyrimidine Biosynthesis by Smee, Donald F, Hurst, Brett L, Day, Craig W

“…Background: The discovery of novel influenza virus inhibitors remains an important priority in light of the emergence of drug-resistant viruses. Toward this…”
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Vaccine production training to develop the workforce of foreign institutions supported by the BARDA influenza vaccine capacity building program by Tarbet, E. Bart, Dorward, James T, Day, Craig W, Rashid, Kamal A

“…Highlights ► BARDA supported vaccine biomanufacturing training at Utah State University. ► Training consisted of three-week industry-focused course for foreign…”
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Antiviral Agents Derived from Novel 1-adamantyl Singlet Nitrenes by Kesel, Andreas J, Weiss, Hans-Christoph, Schönleber, Andreas, Day, Craig W, Barnard, Dale L, Detorio, Mervi A, Schinazi, Raymond F

“…Background: Amantadine constitutes an interesting, diamond crystal lattice-shaped, antivirally active amine with an inhibitory effect on influenza A viruses…”
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Error-prone replication of West Nile virus caused by ribavirin by Day, Craig W., Smee, Donald F., Julander, Justin G., Yamshchikov, Vladimir F., Sidwell, Robert W., Morrey, John D.

“…Ribavirin has been reported to cause error-prone replication and viral extinction in RNA viruses. The antiviral activity of ribavirin against West Nile virus…”
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