Search Results - "DAWOOD, Fayez"

Excessive tumor necrosis factor activation after infarction contributes to susceptibility of myocardial rupture and left ventricular dysfunction by Sun, Mei, Dawood, Fayez, Wen, Wen-Hu, Chen, Manyin, Dixon, Ian, Kirshenbaum, Lorrie A, Liu, Peter P

“…We investigated the potential contributions of tumor necrosis factor-alpha (TNF-alpha) on the incidence of acute myocardial rupture and subsequent chronic…”
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The Primary Benefits of Angiotensin-Converting Enzyme Inhibition on Cardiac Remodeling Occur During Sleep Time in Murine Pressure Overload Hypertrophy by Martino, Tami A., PhD, Tata, Nazneen, MSc, MBBChBAO, Simpson, Jeremy A., PhD, Vanderlaan, Rachel, BSc, Dawood, Fayez, DVM, Kabir, M. Golam, MD, Khaper, Neelam, PhD, Cifelli, Carlo, MSc, Podobed, Peter, BSc, Liu, Peter P., MD, Husain, Mansoor, MD, Heximer, Scott, PhD, Backx, Peter H., DVM, PhD, Sole, Michael J., MD

“…Objectives Our objective was to test the hypothesis that there is a significant diurnal variation for the therapeutic benefit of angiotensin-converting enzyme…”
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Curcumin prevents and reverses murine cardiac hypertrophy by Li, Hong-Liang, Liu, Chen, de Couto, Geoffrey, Ouzounian, Maral, Sun, Mei, Wang, Ai-Bing, Huang, Yue, He, Cheng-Wei, Shi, Yu, Chen, Xin, Nghiem, Mai P, Liu, Youan, Chen, Manyin, Dawood, Fayez, Fukuoka, Masahiro, Maekawa, Yuichiro, Zhang, Liyong, Leask, Andrew, Ghosh, Asish K, Kirshenbaum, Lorrie A, Liu, Peter P

“…Chromatin remodeling, particularly histone acetylation, plays a critical role in the progression of pathological cardiac hypertrophy and heart failure. We…”
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Gelsolin Regulates Cardiac Remodeling After Myocardial Infarction Through DNase I–Mediated Apoptosis by Li, Guo Hua, Shi, Yu, Chen, Yu, Sun, Mei, Sader, Sawsan, Maekawa, Yuichiro, Arab, Sara, Dawood, Fayez, Chen, Manyin, De Couto, Geoffrey, Liu, Youan, Fukuoka, Masahiro, Yang, Stanley, Da Shi, Ming, Kirshenbaum, Lorrie A, McCulloch, Christopher A, Liu, Peter

“…Gelsolin, a calcium-regulated actin severing and capping protein, is highly expressed in murine and human hearts after myocardial infarction and is associated…”
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Stem Cell Factor Receptor Induces Progenitor and Natural Killer Cell-Mediated Cardiac Survival and Repair after Myocardial Infarction by Ayach, Bilal B., Yoshimitsu, Makoto, Dawood, Fayez, Sun, Mei, Arab, Sara, Chen, Manyin, Higuchi, Koji, Siatskas, Christopher, Lee, Paul, Lim, Hilda, Zhang, Jane, Cukerman, Eva, Stanford, William L., Medin, Jeffrey A., Liu, Peter P.

“…Inappropriate cardiac remodeling and repair after myocardial infarction (MI) predisposes to heart failure. Studies have reported on the potential for lineage…”
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The remote ischemic preconditioning stimulus modifies gene expression in mouse myocardium by Konstantinov, Igor E., Arab, Sara, Li, Jia, Coles, John G., Boscarino, Cathy, Mori, Alessandro, Cukerman, Eva, Dawood, Fayez, Cheung, Michael M.H., Shimizu, Mikiko, Liu, Peter P., Redington, Andrew N.

“…We have recently demonstrated that remote ischemic preconditioning reduces ischemia-reperfusion injury in animal models. The mechanisms by which the remote…”
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Endoplasmic Reticulum Resident Protein 44 (ERp44) Deficiency in Mice and Zebrafish Leads to Cardiac Developmental and Functional Defects by Wang, Ding‐Yan, Abbasi, Cynthia, El‐Rass, Suzan, Li, Jamie Yuanjun, Dawood, Fayez, Naito, Kotaro, Sharma, Parveen, Bousette, Nicolas, Singh, Shalini, Backx, Peter H., Cox, Brian, Wen, Xiao‐Yan, Liu, Peter P., Gramolini, Anthony O.

“…Background Endoplasmic reticulum (ER) resident protein 44 (ERp44) is a member of the protein disulfide isomerase family, is induced during ER stress, and may…”
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HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress by Zhang, Liyong, Chen, Xin, Sharma, Parveen, Moon, Mark, Sheftel, Alex D., Dawood, Fayez, Nghiem, Mai P., Wu, Jun, Li, Ren-Ke, Gramolini, Anthony O., Sorensen, Poul H., Penninger, Josef M., Brumell, John H., Liu, Peter P.

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Correction of Cardiac Abnormalities in Fabry Mice by Direct Intraventricular Injection of a Recombinant Lentiviral Vector That Engineers Expression of α-Galactosidase A by Yoshimitsu, Makoto, Higuchi, Koji, Dawood, Fayez, Rasaiah, Vanessa I., Ayach, Bilal, Chen, Manyin, Liu, Peter, Medin, Jeffrey A.

“…Background Recombinant lentiviral vectors (LVs) offer the possibility of stable, long-term expression of transgenes even in non-dividing cells. In the present…”
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Effects of estrogen replacement on infarct size, cardiac remodeling, and the endothelin system after myocardial infarction in ovariectomized rats by SMITH, Paula J. W, ORNATSKY, Olga, STEWART, Duncan J, PICARD, Pierre, DAWOOD, Fayez, WEN, Wen-Hu, LIU, Peter P, WEBB, David J, MONGE, Juan Carlos

“…Estrogen may increase the long-term survival of women who have suffered from a myocardial infarction (MI). We examined the acute and chronic influence of…”
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A serine elastase inhibitor reduces inflammation and fibrosis and preserves cardiac function after experimentally-induced murine myocarditis by Rabinovitch, Marlene, Lee, Jong K, Zaidi, Syed H. E, Liu, Peter, Dawood, Fayez, L.Cheah, Alexander Y, Wen, Wen-Hu, Saiki, Yuriko

“…In viral myocarditis, inflammation and destruction of cardiac myocytes leads to fibrosis, causing progressive impairment in cardiac function. Here we show the…”
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Exercise increases tissue-type plasminogen activator expression in rat cardiomyocytes by Walinski, Hubert P, Gyorffy, Steve F, Leong, Hon S, Slaughter, Graham R D, Dawood, Fayez, Pate, Gordon E, Liu, Peter P, Parker, Thomas G, Podor, Thomas J

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Innate Immune Nod1/RIP2 Signaling Is Essential for Cardiac Hypertrophy but Requires Mitochondrial Antiviral Signaling Protein for Signal Transductions and Energy Balance by Lin, Han-Bin, Naito, Kotaro, Oh, Yena, Farber, Gedaliah, Kanaan, Georges, Valaperti, Alan, Dawood, Fayez, Zhang, Liyong, Li, Guo Hua, Smyth, David, Moon, Mark, Liu, Youan, Liang, Wenbin, Rotstein, Benjamin, Philpott, Dana J., Kim, Kyoung-Han, Harper, Mary-Ellen, Liu, Peter P.

“…BACKGROUND:Cardiac hypertrophy is a key biological response to injurious stresses such as pressure overload and, when excessive, can lead to heart failure…”
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Tumor necrosis factor-α mediates cardiac remodeling and ventricular dysfunction after pressure overload state by MEI SUN, MANYIN CHEN, LIU, Peter P, DAWOOD, Fayez, ZURAWSKA, Urszula, LI, Jeff Y, PARKER, Thomas, KASSIRI, Zamaneh, KIRSHENBAUM, Lorrie A, ARNOLD, Malcolm, KHOKHA, Rama

“…Pressure overload is accompanied by cardiac myocyte apoptosis, hypertrophy, and inflammatory/fibrogenic responses that lead to ventricular remodeling and heart…”
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Simultaneous Transforming Growth Factor β-Tumor Necrosis Factor Activation and Cross-talk Cause Aberrant Remodeling Response and Myocardial Fibrosis in Timp3-deficient Heart by Kassiri, Zamaneh, Defamie, Virginie, Hariri, Mehrdad, Oudit, Gavin Y., Anthwal, Shalini, Dawood, Fayez, Liu, Peter, Khokha, Rama

“…The pleiotropic cytokines, transforming growth factor β1 (TGFβ1), and tumor necrosis factor (TNF) play critical roles in tissue homeostasis in response to…”
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Impaired Heart Contractility in Apelin Gene–Deficient Mice Associated With Aging and Pressure Overload by Kuba, Keiji, Zhang, Liyong, Imai, Yumiko, Arab, Sara, Chen, Manyin, Maekawa, Yuichiro, Leschnik, Michael, Leibbrandt, Andreas, Markovic, Mato, Schwaighofer, Julia, Beetz, Nadine, Musialek, Renata, Neely, G Greg, Komnenovic, Vukoslav, Kolm, Ursula, Metzler, Bernhard, Ricci, Romeo, Hara, Hiromitsu, Meixner, Arabella, Nghiem, Mai, Chen, Xin, Dawood, Fayez, Wong, Kit Man, Sarao, Renu, Cukerman, Eva, Kimura, Akinori, Hein, Lutz, Thalhammer, Johann, Liu, Peter P, Penninger, Josef M

“…Apelin constitutes a novel endogenous peptide system suggested to be involved in a broad range of physiological functions, including cardiovascular function,…”
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L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy by Oudit, Gavin Y, Sun, Hui, Trivieri, Maria G, Koch, Sheryl E, Dawood, Fayez, Ackerley, Cameron, Yazdanpanah, Mehrdad, Wilson, Greg J, Schwartz, Arnold, Liu, Peter P, Backx, Peter H

“…Under conditions of iron overload, which are now reaching epidemic proportions worldwide, iron-overload cardiomyopathy is the most important prognostic factor…”
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Disturbed Diurnal Rhythm Alters Gene Expression and Exacerbates Cardiovascular Disease With Rescue by Resynchronization by Martino, Tami A, Tata, Nazneen, Belsham, Denise D, Chalmers, Jennifer, Straume, Marty, Lee, Paul, Pribiag, Horia, Khaper, Neelam, Liu, Peter P, Dawood, Fayez, Backx, Peter H, Ralph, Martin R, Sole, Michael J

“…Day/night rhythms are recognized as important to normal cardiovascular physiology and timing of adverse cardiovascular events; however, their significance in…”
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Cathepsin-L contributes to cardiac repair and remodelling post-infarction by MEI SUN, MANYIN CHEN, LIU, Youan, FUKUOKA, Masahiro, KIM ZHOU, GUOHUA LI, DAWOOD, Fayez, GRAMOLINI, Anthony, LIU, Peter P

“…Cathepsin-L (CTSL) is a member of the lysozomal cysteine protease family, which participates in remodelling of various tissues. Herein, we sought to examine…”
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Abstract 18619: Scaffold Protein CARD11 Modulates Receptor Mediated Apoptosis in Cardiomyocytes Following Myocardial Infarction by Wood, Philip, Moon, Mark, Zhang, Liyong, Dawood, Fayez, Liu, Youan, Kotaro, Naito, Liu, Peter

“…Abstract only Background: The CARD scaffold family members, named for containing the common caspase-recruitment domain, are important modulators of…”
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