Search Results - "DAVISSON, Vincent Jo"

A Prototype Assay Multiplexing SARS-CoV-2 3CL-Protease and Angiotensin-Converting Enzyme 2 for Saliva-Based Diagnostics in COVID-19 by Suresh, Vallabh, Sheik, Daniel A, Detomasi, Tyler C, Zhao, Tianqi, Zepeda, Theresa, Saladi, Shyam, Rajesh, Ummadisetti Chinna, Byers, Kaleb, Craik, Charles S, Davisson, Vincent Jo

“…With the current state of COVID-19 changing from a pandemic to being more endemic, the priorities of diagnostics will likely vary from rapid detection to…”
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Anti-malarial activity of geldanamycin derivatives in mice infected with Plasmodium yoelii by Mout, Rubul, Xu, Zhi-Dong, Wolf, Angela K H, Jo Davisson, Vincent, Jarori, Gotam K

“…Geldanamycin (GA), a benzoquinone ansamycin antibiotic has been shown in vitro to possess anti-plasmodial activity. Pharmacological activity of this drug is…”
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Glyoxylate protects against cyanide toxicity through metabolic modulation by Nielson, Jason R., Nath, Anjali K., Doane, Kim P., Shi, Xu, Lee, Jangwoen, Tippetts, Emily G., Saha, Kusumika, Morningstar, Jordan, Hicks, Kevin G., Chan, Adriano, Zhao, Yanbin, Kelly, Amy, Hendry-Hofer, Tara B., Witeof, Alyssa, Sips, Patrick Y., Mahon, Sari, Bebarta, Vikhyat S., Davisson, Vincent Jo, Boss, Gerry R., Rutter, Jared, MacRae, Calum A., Brenner, Matthew, Gerszten, Robert E., Peterson, Randall T.

“…Although cyanide’s biological effects are pleiotropic, its most obvious effects are as a metabolic poison. Cyanide potently inhibits cytochrome c oxidase and…”
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Selective Inhibition of STAT3 Phosphorylation Using a Nuclear-Targeted Kinase Inhibitor by Bartolowits, Matthew D, Brown, Wells, Ali, Remah, Pedley, Anthony M, Chen, Qingshou, Harvey, Kyle E, Wendt, Michael K, Davisson, Vincent Jo

“…The discovery of compounds that selectively modulate signaling and effector proteins downstream of EGFR could have important implications for understanding…”
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Computational analysis of high-throughput flow cytometry data by Robinson, J Paul, Rajwa, Bartek, Patsekin, Valery, Davisson, Vincent Jo

“…Flow cytometry has been around for over 40 years, but only recently has the opportunity arisen to move into the high-throughput domain. The technology is now…”
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Translation of a Protease Turnover Assay for Clinical Discrimination of Mucinous Pancreatic Cysts by Suresh, Vallabh, Byers, Kaleb, Rajesh, Ummadisetti Chinna, Caiazza, Francesco, Zhu, Gina, Craik, Charles S., Kirkwood, Kimberly, Davisson, Vincent Jo, Sheik, Daniel A.

“…The classification of pancreatic cyst fluids can provide a basis for the early detection of pancreatic cancer while eliminating unnecessary procedures. A…”
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Multimeric Rhodamine Dye-Induced Aggregation of Silver Nanoparticles for Surface-Enhanced Raman Scattering by Bartolowits, Matthew D, Xin, Meiguo, Petrov, Dino P, Tague, Thomas J, Davisson, Vincent Jo

“…Isotopic variants of Rhodamine 6G (R6G) have previously been used as a method of multiplexed detection for Surface Enhanced Raman Spectroscopy (SERS),…”
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Discovery of Inhibitors for Proliferating Cell Nuclear Antigen Using a Computational-Based Linked-Multiple-Fragment Screen by Bartolowits, Matthew D, Gast, Jonathon M, Hasler, Ashlee J, Cirrincione, Anthony M, O’Connor, Rachel J, Mahmoud, Amr H, Lill, Markus A, Davisson, Vincent Jo

“…Proliferating cell nuclear antigen (PCNA) is a central factor in DNA replication and repair pathways that plays an essential role in genome stability. The…”
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Design, synthesis, and biological evaluation of some 2-(3-oxo-5,6-diphenyl-1,2,4-triazin-2(3H)-yl)-N-phenylacetamide hybrids as MTDLs for Alzheimer's disease therapy by Waiker, Digambar Kumar, Verma, Akash, Gajendra, T.A., Namrata, Roy, Anima, Kumar, Pradeep, Trigun, Surendra Kumar, Srikrishna, Saripella, Krishnamurthy, Sairam, Davisson, Vincent Jo, Shrivastava, Sushant Kumar

“…Inspite of established symptomatic relief drug targets, a multi targeting approach is highly in demand to cure Alzheimer's disease (AD). Simultaneous…”
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Evaluation of potency and metabolic stability of diphyllin-derived Vacuolar-ATPase inhibitors by Sanford, Laura M., Keiser, Patrick, Fujii, Naoaki, Woods, Hannah, Zhang, Charlie, Xu, Zhuangyan, Mahajani, Nivedita S., Cortés, Julián González, Plescia, Caroline B., Knipp, Gregory, Stahelin, Robert V., Davey, Robert, Davisson, Vincent Jo

“…Diphyllin is a naturally occurring lignan comprised of an aryl naphthalene lactone scaffold that demonstrates beneficial biological activities in disease…”
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Investigating the Replacement of Carboxylates with Carboxamides to Modulate the Safety and Efficacy of Platinum(II) Thioether Cyanide Scavengers by Behymer, Matthew M, Mo, Huaping, Fujii, Naoaki, Suresh, Vallabh, Arzumanian, Ari S, Chan, Adriano, Nath, Anjali K, McCain, Robyn, MacRae, Calum A, Peterson, Randall, Boss, Gerry R, Davisson, Vincent Jo, Knipp, Gregory T

“…Cyanide represents a persistent threat for accidental or malicious misuse due to easy conversion into a toxic gas and access to large quantities through…”
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Phenotypic Prioritization of Diphyllin Derivatives That Block Filoviral Cell Entry by Vacuolar (H+)‐ATPase Inhibition by Lindstrom, Aaron, Anantpadma, Manu, Baker, Logan, Raghavendra, N. M., Davey, Robert, Davisson, Vincent Jo

“…Many viruses use endosomal pathways to gain entry into cells and propagate infection. Sensing of endosomal acidification is a trigger for the release of many…”
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Identification of Platinum(II) Sulfide Complexes Suitable as Intramuscular Cyanide Countermeasures by Behymer, Matthew M., Mo, Huaping, Fujii, Naoaki, Suresh, Vallabh, Chan, Adriano, Lee, Jangweon, Nath, Anjali K., Saha, Kusumika, Mahon, Sari B., Brenner, Matthew, MacRae, Calum A., Peterson, Randall, Boss, Gerry R., Knipp, Gregory T., Davisson, Vincent Jo

“…The development of rapidly acting cyanide countermeasures using intramuscular injection (IM) represents an unmet medical need to mitigate toxicant exposures in…”
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Intramuscular administration of glyoxylate rescues swine from lethal cyanide poisoning and ameliorates the biochemical sequalae of cyanide intoxication by Bebarta, Vik S, Shi, Xu, Zheng, Shunning, Hendry-Hofer, Tara B, Severance, Carter C, Behymer, Matthew M, Boss, Gerry R, Mahon, Sari, Brenner, Matthew, Knipp, Gregory T, Davisson, Vincent Jo, Peterson, Randall T, MacRae, Calum A, Rutter, Jared, Gerszten, Robert E, Nath, Anjali K

“…Abstract Cyanide—a fast-acting poison—is easy to obtain given its widespread use in manufacturing industries. It is a high-threat chemical agent that poses a…”
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Design, Synthesis, and Biological Evaluation of Piperazine and N‑Benzylpiperidine Hybrids of 5‑Phenyl-1,3,4-oxadiazol-2-thiol as Potential Multitargeted Ligands for Alzheimer’s Disease Therapy by Waiker, Digambar Kumar, Verma, Akash, Akhilesh, A, Gajendra T., Singh, Namrata, Roy, Anima, Dilnashin, Hagera, Tiwari, Vinod, Trigun, Surendra Kumar, Singh, Surya P., Krishnamurthy, Sairam, Lama, Prem, Davisson, Vincent Jo, Shrivastava, Sushant Kumar

“…Our present work demonstrates the successful design and synthesis of a new class of compounds based upon a multitargeted directed ligand design approach to…”
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Phenotypic Prioritization of Diphyllin Derivatives that Block Filo-viral Cell Entry by Vacuolar (H+)-ATPase Inhibition by Lindstrom, Aaron, Anantpadma, Manu, Baker, Logan, Raghavendra, N.M., Davey, Robert, Davisson, Vincent Jo

“…Many viruses utilize endosomal pathways to gain entry to cells and propagate infection. Sensing of endosomal acidification is a trigger for release of many…”
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Quantitative LC–MS/MS analysis of arachidonoyl amino acids in mouse brain with treatment of FAAH inhibitor by Han, Bingnan, Wright, Rachel, Kirchhoff, Aaron M., Chester, Julia A., Cooper, Bruce R., Davisson, Vincent Jo, Barker, Eric

“…An additional class of endogenous lipid amides, N-arachidonoyl amino acids (Ara-AAs), is growing in significance in the field of endocannabinoids. The…”
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Iejimalides A and B inhibit lysosomal vacuolar H+-ATPase (V-ATPase) activity and induce S-phase arrest and apoptosis in MCF-7 cells by McHenry, Peter, Wang, Wei-Lin Winnie, Devitt, Edward, Kluesner, Nicholas, Davisson, Vincent Jo, McKee, Edward, Schweitzer, Dirk, Helquist, Paul, Tenniswood, Martin

“…Iejimalides are novel macrolides that are cytostatic or cytotoxic against a wide range of cancer cells at low nanomolar concentrations. A recent study by our…”
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Virulence of a phosphoribosylaminoimidazole carboxylase-deficient Candida albicans strain in an immunosuppressed murine model of systemic candidiasis by DONOVAN, Matthew, SCHUMUKE, Jon J, FONZI, William A, BONAR, Sheri L, GHEESLING-MULLIS, Karen, JACOB, Gary S, DAVISSON, Vincent Jo, DOTSON, Stanton B

“…The relative pathogenicities of three Candida albicans strains differing in the function of ADE2 (the gene encoding phosphoribosylaminoimidazole carboxylase)…”
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Virulence of a Phosphoribosylaminoimidazole Carboxylase-DeficientCandida albicans Strain in an Immunosuppressed Murine Model of Systemic Candidiasis by Matthew Donovan, Jon J. Schumuke, William A. Fonzi, Sheri L. Bonar, Karen Gheesling-Mullis, Gary S. Jacob, Vincent Jo Davisson, Stanton B. Dotson

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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