Search Results - "DAVIES, T. F"
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Graves' Disease Mechanisms: The Role of Stimulating, Blocking, and Cleavage Region TSH Receptor Antibodies
Published in Hormone and metabolic research (01-09-2015)“…The immunologic processes involved in Graves' disease (GD) have one unique characteristic--the autoantibodies to the TSH receptor (TSHR)--which have both…”
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A Consensus Report of the Role of Serum Thyroglobulin as a Monitoring Method for Low-Risk Patients with Papillary Thyroid Carcinoma
Published in The journal of clinical endocrinology and metabolism (01-04-2003)“…Recent studies have provided new information regarding the optimal surveillance protocols for low-risk patients with differentiated thyroid cancer (DTC). This…”
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Thyroid and Bone: Macrophage-Derived TSH-β Splice Variant Increases Murine Osteoblastogenesis
Published in Endocrinology (Philadelphia) (01-12-2013)“…It is now firmly established that TSH may influence the physiology and patho-physiology of bone by activating osteoblasts and inhibiting osteoclast activity…”
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T3 Regulates a Human Macrophage-Derived TSH-β Splice Variant: Implications for Human Bone Biology
Published in Endocrinology (Philadelphia) (01-09-2016)“…TSH and thyroid hormones (T3 and T4) are intimately involved in bone biology. We have previously reported the presence of a murine TSH-β splice variant…”
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Thyrotropin receptor-associated diseases: from adenomata to Graves disease
Published in The Journal of clinical investigation (01-08-2005)“…The thyroid-stimulating hormone receptor (TSHR) is a G protein-linked, 7-transmembrane domain (7-TMD) receptor that undergoes complex posttranslational…”
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Defining Thyrotropin-Dependent and -Independent Steps of Thyroid Hormone Synthesis by Using Thyrotropin Receptor-Null Mice
Published in Proceedings of the National Academy of Sciences - PNAS (26-11-2002)“…The thyrotropin (TSH) receptor (TSHR) is a member of the heterotrimeric G protein-coupled family of receptors whose main function is to regulate thyroid cell…”
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Role of the Thyroid-Stimulating Hormone Receptor Signaling in Development and Differentiation of the Thyroid Gland
Published in Proceedings of the National Academy of Sciences - PNAS (26-11-2002)“…The thyroid-stimulating hormone/thyrotropin (TSH) is the most relevant hormone in the control of thyroid gland physiology in adulthood. TSH effects on the…”
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Lipid Rafts Are Triage Centers for Multimeric and Monomeric Thyrotropin Receptor Regulation
Published in Endocrinology (Philadelphia) (01-07-2007)“…The TSH receptor (TSHR), a heptahelical G protein-coupled receptor on the surface of thyrocytes, is a major autoantigen and physiological regulator of the…”
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MYCORRHIZAL FUNGI INCREASE CHROMIUM UPTAKE BY SUNFLOWER PLANTS: INFLUENCE ON TISSUE MINERAL CONCENTRATION, GROWTH, AND GAS EXCHANGE
Published in Journal of plant nutrition (01-09-2002)“…As a potential phytoremediation system for phytoextraction of chromium (Cr), we evaluated the influence of the arbuscular mycorrhizal fungus Glomus…”
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Drought stress influences leaf water content, photosynthesis, and water-use efficiency of Hibiscus rosa-sinensis at three potassium concentrations
Published in Photosynthetica (01-03-2005)Get full text
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Localization and Regulation of Thyrotropin Receptors within Lipid Rafts
Published in Endocrinology (Philadelphia) (01-11-2003)“…The TSH receptor (TSHR) is a prototypic G protein-coupled receptor with a large extracellular domain. We have previously demonstrated homophilic interactions…”
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Intrathyroidal Fetal Microchimerism in Pregnancy and Postpartum
Published in Endocrinology (Philadelphia) (01-01-2002)“…To investigate a possible relationship between fetal microchimerism and autoimmune thyroiditis, we looked for the presence of fetal cells in the maternal blood…”
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A comparison of recombinant human thyrotropin and thyroid hormone withdrawal for the detection of thyroid remnant or cancer
Published in The journal of clinical endocrinology and metabolism (01-11-1999)“…Recombinant human TSH has been developed to facilitate monitoring for thyroid carcinoma recurrence or persistence without the attendant morbidity of…”
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Analysis of the CTLA-4, CD28, and inducible costimulator (ICOS) genes in autoimmune thyroid disease
Published in Genes and immunity (01-12-2003)“…The cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) gene on 2q33 is associated with autoimmune thyroid diseases (AITDs). Our earlier study in 56 families…”
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Monomerization as a Prerequisite for Intramolecular Cleavage and Shedding of the Thyrotropin Receptor
Published in Endocrinology (Philadelphia) (01-12-2004)“…The TSH receptor (TSHR) undergoes intramolecular cleavage of the ectodomain yielding a two-subunit structure on the cell surface. Subsequently, the TSHR…”
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Arginine at position 74 of the HLA-DR β1 chain is associated with Graves' disease
Published in Genes and immunity (01-05-2004)“…Graves' disease (GD) is associated with HLA-DR3 (DRB1*03) in Caucasians, but the exact amino-acid sequence in the DR β1 chain conferring susceptibility to GD…”
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T3 Regulates a Human Macrophage-Derived TSH-[beta] Splice Variant: Implications for Human Bone Biology
Published in Endocrinology (Philadelphia) (01-09-2016)“…TSH and thyroid hormones (T sub(3) and T sub(4)) are intimately involved in bone biology. We have previously reported the presence of a murine TSH-[beta]…”
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Influences of fertilization on Aphis gossypii and insecticide usage. [Erratum: 2005 Apr., v. 129, no. 3, p. 176-184.]
Published in Journal of applied entomology (1986) (01-03-2005)“…: Fertilization levels for ornamental crops may influence pest population dynamics, crop quality, and pest management strategy. We examined the effect of…”
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Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases: Evidence for genetic heterogeneity and gene interactions
Published in The journal of clinical endocrinology and metabolism (01-12-1999)“…The autoimmune thyroid diseases (AITDs), comprising Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of a complex…”
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Comparison of Administration of Recombinant Human Thyrotropin with Withdrawal of Thyroid Hormone for Radioactive Iodine Scanning in Patients with Thyroid Carcinoma
Published in The New England journal of medicine (25-09-1997)“…Thyroid carcinoma is diagnosed in 14,000 people each year in the United States. 1 Most are effectively treated by surgery, followed often by radioiodine…”
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