Search Results - "DAVIES, Susan"

Human primary liver cancer–derived organoid cultures for disease modeling and drug screening by Broutier, Laura, Mastrogiovanni, Gianmarco, Verstegen, Monique MA, Francies, Hayley E, Gavarró, Lena Morrill, Bradshaw, Charles R, Allen, George E, Arnes-Benito, Robert, Sidorova, Olga, Gaspersz, Marcia P, Georgakopoulos, Nikitas, Koo, Bon-Kyoung, Dietmann, Sabine, Davies, Susan E, Praseedom, Raaj K, Lieshout, Ruby, IJzermans, Jan N M, Wigmore, Stephen J, Saeb-Parsy, Kourosh, Garnett, Mathew J, van der Laan, Luc JW, Huch, Meritxell

“…Tumor organoids derived from the most common subtypes of primary liver cancer recapitulate the histologic and molecular features of the tissues of origin, even…”
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Somatic mutations and clonal dynamics in healthy and cirrhotic human liver by Brunner, Simon F., Roberts, Nicola D., Wylie, Luke A., Moore, Luiza, Aitken, Sarah J., Davies, Susan E., Sanders, Mathijs A., Ellis, Pete, Alder, Chris, Hooks, Yvette, Abascal, Federico, Stratton, Michael R., Martincorena, Inigo, Hoare, Matthew, Campbell, Peter J.

“…The most common causes of chronic liver disease are excess alcohol intake, viral hepatitis and non-alcoholic fatty liver disease, with the clinical spectrum…”
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Guidelines on the use of liver biopsy in clinical practice from the British Society of Gastroenterology, the Royal College of Radiologists and the Royal College of Pathology by Neuberger, James, Patel, Jai, Caldwell, Helen, Davies, Susan, Hebditch, Vanessa, Hollywood, Coral, Hubscher, Stefan, Karkhanis, Salil, Lester, Will, Roslund, Nicholas, West, Rebecca, Wyatt, Judith I, Heydtmann, Mathis

“…Liver biopsy is required when clinically important information about the diagnosis, prognosis or management of a patient cannot be obtained by safer means, or…”
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Convergent somatic mutations in metabolism genes in chronic liver disease by Ng, Stanley W. K., Rouhani, Foad J., Brunner, Simon F., Brzozowska, Natalia, Aitken, Sarah J., Yang, Ming, Abascal, Federico, Moore, Luiza, Nikitopoulou, Efterpi, Chappell, Lia, Leongamornlert, Daniel, Ivovic, Aleksandra, Robinson, Philip, Butler, Timothy, Sanders, Mathijs A., Williams, Nicholas, Coorens, Tim H. H., Teague, Jon, Raine, Keiran, Butler, Adam P., Hooks, Yvette, Wilson, Beverley, Birtchnell, Natalie, Naylor, Huw, Davies, Susan E., Stratton, Michael R., Martincorena, Iñigo, Rahbari, Raheleh, Frezza, Christian, Hoare, Matthew, Campbell, Peter J.

“…The progression of chronic liver disease to hepatocellular carcinoma is caused by the acquisition of somatic mutations that affect 20–30 cancer genes 1 – 8 …”
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Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease by Aravinthan, Aloysious, Scarpini, Cinzia, Tachtatzis, Phaedra, Verma, Suman, Penrhyn-Lowe, Sue, Harvey, Rebecca, Davies, Susan E, Allison, Michael, Coleman, Nick, Alexander, Graeme

“…Background & Aims Models of non-alcohol-related fatty liver disease (NAFLD) reveal features of accelerated ageing, such as impaired regeneration, and an…”
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Lipid zonation and phospholipid remodeling in nonalcoholic fatty liver disease by Hall, Zoe, Bond, Nicholas J., Ashmore, Tom, Sanders, Francis, Ament, Zsuzsanna, Wang, Xinzhu, Murray, Andrew J., Bellafante, Elena, Virtue, Sam, Vidal‐Puig, Antonio, Allison, Michael, Davies, Susan E., Koulman, Albert, Vacca, Michele, Griffin, Julian L.

“…Nonalcoholic fatty liver disease (NAFLD) can progress from simple steatosis (i.e., nonalcoholic fatty liver [NAFL]) to nonalcoholic steatohepatitis (NASH),…”
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Cholangiocyte organoids can repair bile ducts after transplantation in the human liver by Sampaziotis, Fotios, Muraro, Daniele, Tysoe, Olivia C, Sawiak, Stephen, Beach, Timothy E, Godfrey, Edmund M, Upponi, Sara S, Brevini, Teresa, Wesley, Brandon T, Garcia-Bernardo, Jose, Mahbubani, Krishnaa, Canu, Giovanni, Gieseck, 3rd, Richard, Berntsen, Natalie L, Mulcahy, Victoria L, Crick, Keziah, Fear, Corrina, Robinson, Sharayne, Swift, Lisa, Gambardella, Laure, Bargehr, Johannes, Ortmann, Daniel, Brown, Stephanie E, Osnato, Anna, Murphy, Michael P, Corbett, Gareth, Gelson, William T H, Mells, George F, Humphreys, Peter, Davies, Susan E, Amin, Irum, Gibbs, Paul, Sinha, Sanjay, Teichmann, Sarah A, Butler, Andrew J, See, Teik Choon, Melum, Espen, Watson, Christopher J E, Saeb-Parsy, Kourosh, Vallier, Ludovic

“…Organoid technology holds great promise for regenerative medicine but has not yet been applied to humans. We address this challenge using cholangiocyte…”
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Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial by Jacobs, Ian J, Prof, Menon, Usha, Prof, Ryan, Andy, PhD, Gentry-Maharaj, Aleksandra, PhD, Burnell, Matthew, PhD, Kalsi, Jatinderpal K, PhD, Amso, Nazar N, Prof, Apostolidou, Sophia, PhD, Benjamin, Elizabeth, FRCPath, Cruickshank, Derek, FRCOG, Crump, Danielle N, BSN, Davies, Susan K, RGN, Dawnay, Anne, PhD, Dobbs, Stephen, FRCOG, Fletcher, Gwendolen, DCR(R), Ford, Jeremy, MSc, Godfrey, Keith, FRCOG, Gunu, Richard, MSc, Habib, Mariam, PhD, Hallett, Rachel, PhD, Herod, Jonathan, MRCOG, Jenkins, Howard, FRCOG, Karpinskyj, Chloe, BSc, Leeson, Simon, FRCOG, Lewis, Sara J, MSc, Liston, William R, Lopes, Alberto, FRCOG, Mould, Tim, FRCOG, Murdoch, John, FRCOG, Oram, David, FRCOG, Rabideau, Dustin J, MSc, Reynolds, Karina, FRCOG, Scott, Ian, FRCOG, Seif, Mourad W, FRCOG, Sharma, Aarti, PhD, Singh, Naveena, FRCPath, Taylor, Julie, MSc, Warburton, Fiona, MSc, Widschwendter, Martin, Prof, Williamson, Karin, FRCOG, Woolas, Robert, MD, Fallowfield, Lesley, Prof, McGuire, Alistair J, Prof, Campbell, Stuart, Prof, Parmar, Mahesh, Prof, Skates, Steven J, PhD

“…Summary Background Ovarian cancer has a poor prognosis, with just 40% of patients surviving 5 years. We designed this trial to establish the effect of early…”
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OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer by Damgaard, Rune Busk, Jolin, Helen E., Allison, Michael E. D., Davies, Susan E., Titheradge, Hannah L., McKenzie, Andrew N. J., Komander, David

“…Methionine-1 (M1)-linked polyubiquitin chains conjugated by the linear ubiquitin chain assembly complex (LUBAC) control NF-κB activation, immune homoeostasis,…”
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Racial and Ethnic Disparities in ADHD Diagnosis and Treatment by Coker, Tumaini R, Elliott, Marc N, Toomey, Sara L, Schwebel, David C, Cuccaro, Paula, Tortolero Emery, Susan, Davies, Susan L, Visser, Susanna N, Schuster, Mark A

“…We examined racial/ethnic disparities in attention-deficit/hyperactivity disorder (ADHD) diagnosis and medication use and determined whether medication…”
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Exploring the care coordination experiences of professionals and caregivers of youth with acquired brain injuries in rural areas by Yoder, Emilie M, Davies, Susan C, Montgomery, Meredith, Lundine, Jennifer P

“…Acquired brain injuries (ABIs) can have devastating effects on children and their families. Families living in rural communities experience unique barriers to…”
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Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) by Menon, Usha, Dr, Gentry-Maharaj, Aleksandra, PhD, Hallett, Rachel, PhD, Ryan, Andy, PhD, Burnell, Matthew, PhD, Sharma, Aarti, MRCOG, Lewis, Sara, MSc, Davies, Susan, RGN, Philpott, Susan, MSc, Lopes, Alberto, FRCOG, Godfrey, Keith, FRCOG, Oram, David, FRCOG, Herod, Jonathan, MRCOG, Williamson, Karin, FRCOG, Seif, Mourad W, FRCOG, Scott, Ian, FRCOG, Mould, Tim, FRCOG, Woolas, Robert, MD, Murdoch, John, FRCOG, Dobbs, Stephen, MRCOG, Amso, Nazar N, PhD, Leeson, Simon, FRCOG, Cruickshank, Derek, FRCOG, Mcguire, Alistair, Prof, Campbell, Stuart, Prof, Fallowfield, Lesley, Prof, Singh, Naveena, FRCPath, Dawnay, Anne, PhD, Skates, Steven J, PhD, Parmar, Mahesh, Prof, Jacobs, Ian, Prof

“…Summary Background Ovarian cancer has a high case–fatality ratio, with most women not diagnosed until the disease is in its advanced stages. The United Kingdom…”
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Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation by Sampaziotis, Fotios, Cardoso de Brito, Miguel, Madrigal, Pedro, Bertero, Alessandro, Saeb-Parsy, Kourosh, Soares, Filipa A C, Schrumpf, Elisabeth, Melum, Espen, Karlsen, Tom H, Bradley, J Andrew, Gelson, William T H, Davies, Susan, Baker, Alastair, Kaser, Arthur, Alexander, Graeme J, Hannan, Nicholas R F, Vallier, Ludovic

“…A protocol for generating biliary epithelial cells from human pluripotent stem cells facilitates disease modeling and drug screening. The study of biliary…”
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Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis by Tachtatzis, Phaedra M, Marshall, Aileen, Arvinthan, Aloysious, Aravinthan, Aloysius, Verma, Suman, Penrhyn-Lowe, Sue, Mela, Marianna, Scarpini, Cinzia, Davies, Susan E, Coleman, Nicholas, Alexander, Graeme J M

“…Chronic Hepatitis B virus (HBV) infection can lead to the development of chronic hepatitis, cirrhosis and hepatocellular carcinoma. We hypothesized that HBV…”
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School-Based Support for Families of Students with Traumatic Brain Injuries by Davies, Susan C.

“…Families of children with traumatic brain injuries (TBIs) often experience emotional burden related to the sudden onset, intensity, and duration of the…”
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Intercalibration of aquatic ecological assessment methods in the European Union: Lessons learned and way forward by Poikane, Sandra, Zampoukas, Nikolaos, Borja, Angel, Davies, Susan P., van de Bund, Wouter, Birk, Sebastian

“…•Over 300 aquatic ecological assessment methods are currently in use across Europe.•To ensure methods comparability, intercalibration was carried out by Member…”
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Spleen Size Does Not Correlate With Histological Stage of Liver Disease in People With Nonalcoholic Fatty Liver Disease by Cacciottolo, Tessa M., Kumar, Anupa, Godfrey, Edmund M., Davies, Susan E., Allison, Michael

“…Splenomegaly in the context of liver disease is classically associated with advanced cirrhosis and portal hypertension.1 More recently, we observed an…”
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Care Coordination for Children with Special Health Care Needs: A Scoping Review to Inform Strategies for Students with Traumatic Brain Injuries by Davies, Susan C., Lundine, Jennifer P., Justice, Ann F.

“…ABSTRACT BACKGROUND Chronic and complex medical issues, including traumatic brain injuries (TBIs), have significant educational implications. The purpose of…”
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The Biological Condition Gradient: A Descriptive Model for Interpreting Change in Aquatic Ecosystems by Davies, Susan P., Jackson, Susan K.

“…The United States Clean Water Act (CWA; 1972, and as amended, U.S. Code title 33, sections 1251-1387) provides the long-term, national objective to "restore…”
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SCHOOL-BASED TRAUMATIC BRAIN INJURY AND CONCUSSION MANAGEMENT PROGRAM by Davies, Susan C.

“…Traumatic brain injuries (TBIs), including concussions, can result in a constellation of physical, cognitive, emotional, and behavioral symptoms that affect…”
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