Search Results - "DAVIES, PETER J. A."

A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells by Guo, Lei, Li, Jia, Zeng, Hongxiang, Guzman, Anna G., Li, Tingting, Lee, Minjung, Zhou, Yubin, Goodell, Margaret A., Stephan, Clifford, Davies, Peter J. A., Dawson, Mark A, Sun, Deqiang, Huang, Yun

“…Primary and acquired drug resistance imposes a major threat to achieving optimized clinical outcomes during cancer treatment. Aberrant changes in epigenetic…”
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Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists by Mukherjee, Ranjan, Davies, Peter J. A, Crombie, Diane L, Bischoff, Eric D, Cesario, Rosemary M, Jow, Lily, Hamann, Lawrence G, Boehm, Marcus F, Mondon, Carl E, Nadzan, Alex M, Paterniti, James R, Heyman, Richard A

“…Retinoic acid receptors (RAR), thyroid hormone receptors (TR), peroxisome proliferator activated receptors (PPARs) and the orphan receptor, LXR, bind…”
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Publisher Correction: Epigenetic alterations of repeated relapses in patient-matched childhood ependymomas by Zhao, Sibo, Li, Jia, Zhang, Huiyuan, Qi, Lin, Du, Yuchen, Kogiso, Mari, Braun, Frank K., Xiao, Sophie, Huang, Yulun, Li, Jianfang, Teo, Wan-Yee, Lindsay, Holly, Baxter, Patricia, Su, Jack M. F., Adesina, Adekunle, Laczik, Miklós, Genevini, Paola, Veillard, Anne-Clemence, Schvartzman, Sol, Berguet, Geoffrey, Ding, Shi-Rong, Du, Liping, Stephan, Clifford, Yang, Jianhua, Davies, Peter J. A., Lu, Xinyan, Chintagumpala, Murali, Parsons, Donald William, Perlaky, Laszlo, Xia, Yun-Fei, Man, Tsz-Kwong, Huang, Yun, Sun, Deqiang, Li, Xiao-Nan

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Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas by Zhao, Sibo, Li, Jia, Zhang, Huiyuan, Qi, Lin, Du, Yuchen, Kogiso, Mari, Braun, Frank K., Xiao, Sophie, Huang, Yulun, Li, Jianfang, Teo, Wan-Yee, Lindsay, Holly, Baxter, Patricia, Su, Jack M. F., Adesina, Adekunle, Laczik, Miklós, Genevini, Paola, Veillard, Anne-Clemence, Schvartzman, Sol, Berguet, Geoffrey, Ding, Shi-Rong, Du, Liping, Stephan, Clifford, Yang, Jianhua, Davies, Peter J. A., Lu, Xinyan, Chintagumpala, Murali, Parsons, Donald William, Perlaky, Laszlo, Xia, Yun-Fei, Man, Tsz-Kwong, Huang, Yun, Sun, Deqiang, Li, Xiao-Nan

“…Recurrence is frequent in pediatric ependymoma (EPN). Our longitudinal integrated analysis of 30 patient-matched repeated relapses (3.67 ± 1.76 times) over 13…”
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Arginine Methylation Provides Epigenetic Transcription Memory for Retinoid-Induced Differentiation in Myeloid Cells by Balint, Balint L, Szanto, Attila, Madi, Andras, Bauer, Uta-Maria, Gabor, Petra, Benko, Szilvia, Puskás, Laszlo G, Davies, Peter J A, Nagy, Laszlo

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Coordinate Regulation of the Production and Signaling of Retinoic Acid by Estrogen in the Human Endometrium by Deng, Lei, Shipley, Gregory L., Loose-Mitchell, David S., Stancel, George M., Broaddus, Russell, Pickar, James H., Davies, Peter J. A.

“…To determine whether estrogen regulates retinoic acid (RA) production and signaling in the human endometrium as it does in the rodent uterus, we investigated…”
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Overexpression of the Insulin-Like Growth Factor I Receptor and Activation of the AKT Pathway in Hyperplastic Endometrium by McCampbell, Adrienne S, Broaddus, Russell R, Loose, David S, Davies, Peter J A

“…Purpose: Although there is considerable information on the molecular aberrations associated with endometrial cancer, very little is known of the changes in…”
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Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors by Anakk, Sayeepriyadarshini, Kalsotra, Auinash, Shen, Qi, Vu, Mary T., Staudinger, Jeffrey L., Davies, Peter J. A., Strobel, Henry W.

“…ABSTRACT We report that CYP3a13 gene, located on mouse chromosome 5, spans 27.5 Kb and contains 13 exons. The transcription start site is 35 bp upstream of the…”
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Developmental reprogramming of IGF signaling and susceptibility to endometrial hyperplasia in the rat by McCampbell, Adrienne S, Walker, Cheryl L, Broaddus, Russell R, Cook, Jennifer D, Davies, Peter J A

“…In rodents, a brief neonatal exposure of the developing reproductive tract to the xenoestrogen, diethylstilbestrol (DES) reprograms developing tissues to…”
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Enhanced estrogen-induced proliferation in obese rat endometrium by Zhang, Qian, PhD, Shen, Qi, MD, PhD, Celestino, Joseph, Milam, Michael R., MD, Westin, Shannon N., MD, Lacour, Robin A., MD, Meyer, Larissa A., MD, Shipley, Gregory L., PhD, Davies, Peter J.A., MD, PhD, Deng, Lei, PhD, McCampbell, Adrienne S., PhD, Broaddus, Russell R., MD, PhD, Lu, Karen H., MD

“…Objective We tested the hypothesis that the proliferative estrogen effect on the endometrium is enhanced in obese vs lean animals. Study Design Using Zucker…”
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Estrogen regulation of the cytochrome P450 3A subfamily in humans by Williams, Eric T, Leyk, Małgorzata, Wrighton, Steven A, Davies, Peter J A, Loose, David S, Shipley, Gregory L, Strobel, Henry W

“…This study examines the possible role of estrogen in regulating the expression of the human CYP3A subfamily: CYP3A4, CYP3A5, CYP3A7, and CYP3A43. To accomplish…”
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Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis by Wang, Shan, Rao, Wei, Hoffman, Ashley, Lin, Jennifer, Li, Justin, Lin, Tao, Liew, Audrey-Ann, Vincent, Matthew, Mertens, Tinne C J, Karmouty-Quintana, Harry, Crum, Christopher P, Metersky, Mark L, Schwartz, David A, Davies, Peter J A, Stephan, Clifford, Jyothula, Soma S K, Sheshadri, Ajay, Suarez, Erik Eddie, Huang, Howard J, Engelhardt, John F, Dickey, Burton F, Parekh, Kalpaj R, McKeon, Frank D, Xian, Wa

“…Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible, and rapidly fatal interstitial lung disease marked by the replacement of lung alveoli with…”
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Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma by Li, Jia, Zhao, Sibo, Lee, Minjung, Yin, Yue, Li, Jin, Zhou, Yubin, Ballester, Leomar Y, Esquenazi, Yoshua, Dashwood, Roderick H, Davies, Peter J A, Parsons, D Williams, Li, Xiao-Nan, Huang, Yun, Sun, Deqiang

“…Medulloblastoma (MB), the most common form of pediatric brain malignancy, has a low frequency of oncogenic mutations but pronouncedly abnormal DNA methylation…”
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Identification of a Novel Estrogen-Regulated Gene, EIG121, Induced by Hormone Replacement Therapy and Differentially Expressed in Type I and Type II Endometrial Cancer by Deng, Lei, Broaddus, Russell R, McCampbell, Adrienne, Shipley, Gregory L, Loose, David S, Stancel, George M, Pickar, James H, Davies, Peter J A

“…Purpose: The identification of genes and pathways that are affected by estrogenization may shed light on the mechanisms of estrogen action. Here, we describe…”
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Injury‐induced ‘switch’ from GTP‐regulated to novel GTP‐independent isoform of tissue transglutaminase in the rat spinal cord by Festoff, Barry W., SantaCruz, Karen, Arnold, Paul M., Sebastian, Cyril T., Davies, Peter J. A., Citron, Bruce A.

“…We recently found that alternative transcripts of tissue transglutaminase (tTG or TG2) were present in hippocampal brain regions of Alzheimer's disease (AD),…”
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Downregulation of metabolic gene expression in failing human heart before and after mechanical unloading by Razeghi, Peter, Young, Martin E, Ying, Jun, Depre, Christophe, Uray, Ivan P, Kolesar, June, Shipley, Gregory L, Moravec, Christine S, Davies, Peter J A, Frazier, O H, Taegtmeyer, Heinrich

“…We have previously shown that several metabolic genes are downregulated in the failing human heart. We now tested the hypothesis that mechanical unloading…”
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Regulation of the Expression of the Tissue Transglutaminase Gene by DNA Methylation by Lu, Shan, Peter J. A. Davies

“…We have investigated the role of DNA methylation in the regulation of the expression of the human tissue transglutaminase gene. Studies on the methylation of…”
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Synthesis and Structure−Activity Relationships of Retinoid X Receptor Selective Diaryl Sulfide Analogs of Retinoic Acid by Beard, Richard L, Colon, Diana F, Song, Tae K, Davies, Peter J. A, Kochhar, Devendra M, Chandraratna, Roshantha A. S

“…Retinoids exert their biological effects by binding to and activating nuclear receptors that interact with responsive elements on DNA to promote gene…”
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Protein crosslinking, tissue transglutaminase, alternative splicing and neurodegeneration by Citron, Bruce A, Suo, Zhiming, SantaCruz, Karen, Davies, Peter J.A, Qin, Frank, Festoff, Barry W

“…Increasing interest and awareness of protein aggregation as being implicated in neurodegenerative processes has developed in recent years. One novel mechanism…”
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Effects of Rexinoids on Glucose Transport and Insulin-mediated Signaling in Skeletal Muscles of Diabetic (db/db) Mice by Shen, Qi, Cline, Gary W, Shulman, Gerald I, Leibowitz, Mark D, Davies, Peter J A

“…Rexinoids and thiazolidinediones (TZDs) are two classes of nuclear receptor ligands that induce insulin sensitization in diabetic rodents. TZDs are peroxisome…”
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