Search Results - "DAVIDSON, MARI"

Molecular mechanisms for environmentally induced and evolutionarily rapid redistribution (plasticity) of meiotic recombination by Protacio, Reine U, Mukiza, Tresor O, Davidson, Mari K, Wahls, Wayne P

“…Abstract It has long been known (circa 1917) that environmental conditions, as well as speciation, can affect dramatically the frequency distribution of…”
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Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution by Protacio, Reine U, Davidson, Mari K, Wahls, Wayne P

“…Meiosis is an essential component of the sexual life cycle in eukaryotes. The independent assortment of chromosomes in meiosis increases genetic diversity at…”
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Diverse DNA Sequence Motifs Activate Meiotic Recombination Hotspots Through a Common Chromatin Remodeling Pathway by Mukiza, Tresor O, Protacio, Reine U, Davidson, Mari K, Steiner, Walter W, Wahls, Wayne P

“…In meiosis, multiple different DNA sequence motifs help to position homologous recombination at hotspots in the genome. How do the seemingly disparate -acting…”
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Creating Meiotic Recombination-Regulating DNA Sites by SpEDIT in Fission Yeast Reveals Inefficiencies, Target-Site Duplications, and Ectopic Insertions by Protacio, Reine U, Dixon, Seth, Davidson, Mari K, Wahls, Wayne P

“…Recombination hotspot-activating DNA sites (e.g., , , ) and their binding proteins (e.g., Atf1-Pcr1 heterodimer; Php2-Php3-Php5 complex, Rst2, Prdm9) regulate…”
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Agar lot-specific inhibition in the plating efficiency of yeast spores and cells by Protacio, Reine U, Davidson, Mari K, Malone, Emory G, Helmlinger, Dominique, Smith, Jeremy R, Gibney, Patrick A, Wahls, Wayne P

“…The fission yeast Schizosaccharomyces pombe and the budding yeast Saccharomyces cerevisiae are highly diverged (530 mya), single-celled, model eukaryotic…”
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Discrete DNA sites regulate global distribution of meiotic recombination by Wahls, Wayne P, Davidson, Mari K

“…Homologous recombination is induced to high levels in meiosis, is initiated by Spo11-catalyzed DNA double-strand breaks (DSBs) and is clustered at hotspots…”
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Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot by Storey, Aaron J, Wang, Hsin-Ping, Protacio, Reine U, Davidson, Mari K, Tackett, Alan J, Wahls, Wayne P

“…Meiotic recombination hotspots control the frequency and distribution of Spo11 (Rec12)-initiated recombination in the genome. Recombination occurs within and…”
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DNA sequence-mediated, evolutionarily rapid redistribution of meiotic recombination hotspots by Wahls, Wayne P, Davidson, Mari K

“…Hotspots regulate the position and frequency of Spo11 (Rec12)-initiated meiotic recombination, but paradoxically they are suicidal and are somehow resurrected…”
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Meiotic recombination protein Rec12: functional conservation, crossover homeostasis and early crossover/non-crossover decision by Kan, Fengling, Davidson, Mari K, Wahls, Wayne P

“…In fission yeast and other eukaryotes, Rec12 (Spo11) is thought to catalyze the formation of dsDNA breaks (DSBs) that initiate homologous recombination in…”
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Galectin-3 is a substrate for prostate specific antigen (PSA) in human seminal plasma by Saraswati, Sarika, Block, Ashley S., Davidson, Mari. K., Rank, Roger. G., Mahadevan, Maha, Diekman, Alan B.

“…BACKGROUND Galectin‐3 is a multivalent carbohydrate‐binding protein involved in cell adhesion, cell cycle control, immunomodulation, and cancer progression,…”
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Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast by Storey, Aaron J, Wang, Hsin-Ping, Protacio, Reine U, Davidson, Mari K, Wahls, Wayne P

“…Precise allele replacement (genome editing), without unwanted changes to the genome, provides a powerful tool to define the functions of DNA elements and…”
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New paradigms for conserved, multifactorial, cis-acting regulation of meiotic recombination by Wahls, Wayne P, Davidson, Mari K

“…How do cells position the Spo11 (Rec12)-dependent initiation of meiotic recombination at hotspots? The mechanisms are poorly understood and a prevailing view…”
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Meiotic recombination hotspots of fission yeast are directed to loci that express non-coding RNA by Wahls, Wayne P, Siegel, Eric R, Davidson, Mari K

“…Polyadenylated, mRNA-like transcripts with no coding potential are abundant in eukaryotes, but the functions of these long non-coding RNAs (ncRNAs) are…”
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Phosphorylation-Independent Regulation of Atf1-Promoted Meiotic Recombination by Stress-Activated, p38 Kinase Spc1 of Fission Yeast by Gao, Jun, Davidson, Mari K, Wahls, Wayne P

“…Background: Stress-activated protein kinases regulate multiple cellular responses to a wide variety of intracellular and extracellular conditions. The…”
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A Stress-Activated, p38 Mitogen-Activated Protein Kinase–ATF/CREB Pathway Regulates Posttranscriptional, Sequence-Dependent Decay of Target RNAs by Gao, Jun, Wagnon, Jacy L., Protacio, Reine M., Glazko, Galina V., Beggs, Marjorie, Raj, Vinay, Davidson, Mari K., Wahls, Wayne P.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Rapid, efficient and precise allele replacement in the fission yeast Schizosaccharomyces pombe by Gao, Jun, Kan, Fengling, Wagnon, Jacy L, Storey, Aaron J, Protacio, Reine U, Davidson, Mari K, Wahls, Wayne P

“…Gene targeting provides a powerful tool to modify endogenous loci to contain specific mutations, insertions and deletions. Precise allele replacement, with no…”
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The Syphilis Testing Result Interprofessional Counseling and Education (STRICE) simulation by Nunez-Argote, Letycia, Robertson, Cherika, Teigen, Amber, Gilbert, Lindsay, Neill, Kathryn K, Anders, Michael, Davidson, Mari K

“…AbstractThe Syphilis Testing Result Interprofessional Counseling and Education simulation provides a scenario where students of a variety of health professions…”
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Nonsense codon suppression in fission yeast due to mutations of tRNA(Ser.11) and translation release factor Sup35 (eRF3) by Protacio, Reine U, Storey, Aaron J, Davidson, Mari K, Wahls, Wayne P

“…In the fission yeast Schizosaccharomyces pombe, sup9 mutations can suppress the termination of translation at nonsense (stop) codons. We localized sup9…”
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Distinct regions of ATF/CREB proteins Atf1 and Pcr1 control recombination hotspot ade6-M26 and the osmotic stress response by Gao, Jun, Davidson, Mari K, Wahls, Wayne P

“…The Atf1 protein of Schizosaccharomyces pombe contains a bZIP (DNA-binding/protein dimerization) domain characteristic of ATF/CREB proteins, but no other…”
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Atf1-Pcr1-M26 Complex Links Stress-activated MAPK and cAMP-dependent Protein Kinase Pathways via Chromatin Remodeling of cgs2 by Davidson, Mari K., Shandilya, Harish K., Hirota, Kouji, Ohta, Kunihiro, Wahls, Wayne P.

“…Although co-ordinate interaction between different signal transduction pathways is essential for developmental decisions, interpathway connections are often…”
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