Search Results - "DAVALLI, Alberto M"

Pancreatic islet of Langerhans' cytoarchitecture and ultrastructure in normal glucose tolerance and in type 2 diabetes mellitus by Folli, Franco, La Rosa, Stefano, Finzi, Giovanna, Davalli, Alberto M., Galli, Alessandra, Dick, Edward J., Perego, Carla, Mendoza, Rodolfo Guardado

“…While a number of structural and cellular abnormalities occur in the islet of Langerhans in diabetes, and in particular in type 2 diabetes, the focus has been…”
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The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism by Andreozzi, Francesco, Raciti, Gregory Alexander, Nigro, Cecilia, Mannino, Gaia Chiara, Procopio, Teresa, Davalli, Alberto M, Beguinot, Francesco, Sesti, Giorgio, Miele, Claudia, Folli, Franco

“…Potentiation of glucose-induced insulin secretion is the main mechanism of exenatide (EXE) antidiabetic action, however, increased glucose utilization by…”
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Autoantibodies against the glial glutamate transporter GLT1/EAAT2 in Type 1 diabetes mellitus—Clues to novel immunological and non-immunological therapies by Perego, Carla, Di Cairano, Eliana S., Galli, Alessandra, Moretti, Stefania, Bazzigaluppi, Elena, Centonze, Victoria Frolich, Gastaldelli, Amalia, Assi, Emma, Fiorina, Paolo, Federici, Massimo, Porzio, Ottavia, Bertuzzi, Federico, Davalli, Alberto M., Folli, Franco

“…Islet cell surface autoantibodies were previously found in subjects with type 1 diabetes mellitus (T1DM), but their target antigens and pathogenic mechanisms…”
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Energy expenditure evaluation in humans and non-human primates by SenseWear Armband. Validation of energy expenditure evaluation by SenseWear Armband by direct comparison with indirect calorimetry by Casiraghi, Francesca, Lertwattanarak, Raweewan, Luzi, Livio, Chavez, Alberto O, Davalli, Alberto M, Naegelin, Terry, Comuzzie, Anthony G, Frost, Patricia, Musi, Nicolas, Folli, Franco

“…The purpose of this study was to compare and validate the use of SenseWear Armband (SWA) placed on the arm (SWA ARM) and on the back (SWA BACK) in healthy…”
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Pancreatic islet amyloidosis, β-cell apoptosis, and α-cell proliferation are determinants of islet remodeling in type-2 diabetic baboons by Guardado-Mendoza, Rodolfo, Davalli, Alberto M, Chavez, Alberto O, Hubbard, Gene B, Dick, Edward J, Majluf-Cruz, Abraham, Tene-Perez, Carlos E, Goldschmidt, Lukasz, Hart, John, Perego, Carla, Comuzzie, Anthony G, Tejero, Maria Elizabeth, Finzi, Giovanna, Placidi, Claudia, La Rosa, Stefano, Capella, Carlo, Halff, Glenn, Gastaldelli, Amalia, DeFronzo, Ralph A, Folli, Franco

“…β-Cell dysfunction is an important factor in the development of hyperglycemia of type-2 diabetes mellitus, and pancreatic islet amyloidosis (IA) has been…”
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Vulnerability of islets in the immediate posttransplantation period : Dynamic changes in structure and function by DAVALLI, A. M, SCAGLIA, L, ZANGEN, D. H, HOLLISTER, J, BONNER-WEIR, S, WEIR, G. C

“…To learn more about islet vulnerability in the immediate posttransplant period, 400 syngeneic islets were transplanted under the kidney capsule of B6AF1 mice…”
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Effects of balloon injury on neointimal hyperplasia in streptozotocin-induced diabetes and in hyperinsulinemic nondiabetic pancreatic islet-transplanted rats by INDOLFI, Ciro, TORELLA, Daniele, PERRINO, Cinzia, CHIEFFO, Alaide, PARDO, Francesco, CHIARIELLO, Massimo, CAVUTO, Luigi, DAVALLI, Alberto M, COPPOLA, Carmela, ESPOSITO, Giovanni, CARRIERO, Mariolina V, RAPACCIUOLO, Antonio, DI LORENZO, Emilio, STABILE, Eugenio

“…The mechanisms of increased neointimal hyperplasia after coronary interventions in diabetic patients are still unknown. Glucose and insulin effects on in vitro…”
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Disproportionate hyperproinsulinemia, beta-cell restricted prohormone convertase 2 deficiency, and cell cycle inhibitors expression by human islets transplanted into athymic nude mice: insights into nonimmune-mediated mechanisms of delayed islet graft failure by Davalli, Alberto M, Perego, Lucia, Bertuzzi, Federico, Finzi, Giovanna, La Rosa, Stefano, Blau, Adam, Placidi, Claudia, Nano, Rita, Gregorini, Luisa, Perego, Carla, Capella, Carlo, Folli, Franco

“…To learn more about nonimmune-mediated islet graft failure, we transplanted different preparations (preps) of isolated human islets under the kidney capsule of…”
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The potential role of glutamate in the current diabetes epidemic by Davalli, Alberto M., Perego, Carla, Folli, Franco B.

“…In the present article, we propose the perspective that abnormal glutamate homeostasis might contribute to diabetes pathogenesis. Previous reports and our…”
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Effects of Streptozocin Diabetes and Diabetes Treatment by Islet Transplantation on In Vivo Insulin Signaling in Rat Heart by LAVIOLA, Luigi, BELSANTI, Gaetana, DAVALLI, Alberto M, NAPOLI, Raffaele, PERRINI, Sebastio, WEIR, Gordon C, GIORGINO, Riccardo, GIORGINO, Francesco

“…Effects of Streptozocin Diabetes and Diabetes Treatment by Islet Transplantation on In Vivo Insulin Signaling in Rat Heart Luigi Laviola 1 , Gaetana Belsanti 1…”
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Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas) by Guardado Mendoza, Rodolfo, Perego, Carla, Finzi, Giovanna, La Rosa, Stefano, Capella, Carlo, Jimenez-Ceja, Lilia M., Velloso, Licio A., Saad, Mario J. A., Sessa, Fausto, Bertuzzi, Federico, Moretti, Stefania, Dick, Edward J., Davalli, Alberto M., Folli, Franco

“…Aims/hypothesis The cellular composition of the islet of Langerhans is essential to ensure its physiological function. Morphophysiological islet abnormalities…”
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The Glial Glutamate Transporter 1 (GLT1) Is Expressed by Pancreatic β-Cells and Prevents Glutamate-induced β-Cell Death by Di Cairano, Eliana S., Davalli, Alberto M., Perego, Lucia, Sala, Silvia, Sacchi, V. Franca, La Rosa, Stefano, Finzi, Giovanna, Placidi, Claudia, Capella, Carlo, Conti, Paola, Centonze, Victoria E., Casiraghi, Francesca, Bertuzzi, Federico, Folli, Franco, Perego, Carla

“…Glutamate is the major excitatory neurotransmitter of the central nervous system (CNS) and may induce cytotoxicity through persistent activation of glutamate…”
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Further Evidence for Amyloid Deposition in Clinical Pancreatic Islet Grafts by WESTERMARK, Gunilla T, DAVALLI, Alberto M, WESTERMARK, Per, SECCHI, Antonio, FOLLI, Franco, KIN, Tatsuya, TOSO, Christian, JAMES SHAPIRO, A. M, KORSGREN, Olle, TUFVESON, Gunnar, ANDERSSON, Arne

“…The reasons for the long-term complete or partial loss of islet graft function are unknown, but there are obviously other reasons than just pure allogeneic…”
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Exenatide regulates pancreatic islet integrity and insulin sensitivity in the nonhuman primate baboon Papio hamadryas by Fiorentino, Teresa Vanessa, Casiraghi, Francesca, Davalli, Alberto M, Finzi, Giovanna, La Rosa, Stefano, Higgins, Paul B, Abrahamian, Gregory A, Marando, Alessandro, Sessa, Fausto, Perego, Carla, Guardado-Mendoza, Rodolfo, Kamath, Subhash, Ricotti, Andrea, Fiorina, Paolo, Daniele, Giuseppe, Paez, Ana M, Andreozzi, Francesco, Bastarrachea, Raul A, Comuzzie, Anthony G, Gastaldelli, Amalia, Chavez, Alberto O, Di Cairano, Eliana S, Frost, Patrice, Luzi, Livio, Dick, Edward J, Halff, Glenn A, DeFronzo, Ralph A, Folli, Franco

“…The glucagon-like peptide-1 receptor agonist exenatide improves glycemic control by several and not completely understood mechanisms. Herein, we examined the…”
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High glucose causes apoptosis in cultured human pancreatic islets of Langerhans : A potential role for regulation of specific Bcl family genes toward an apoptotic cell death program by FEDERICI, Massimo, HRIBAL, Marta, MARLIER, Lionel N. J. L, DAVALLI, Alberto M, CARANDENTE, Orazio, PONTIROLI, Antonio E, MELINO, Gerry, MARCHETTI, Piero, LAURO, Renato, SESTI, Giorgio, FOLLI, Franco, PEREGO, Lucia, RANALLI, Marco, CARADONNA, Zaira, PEREGO, Carla, USELLINI, Luciana, NANO, Rita, BONINI, Paolo, BERTUZZI, Federico

“…Type 2 diabetes is characterized by insulin resistance and inadequate insulin secretion. In the advanced stages of the disease, beta-cell dysfunction worsens…”
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Coordinated defects in hepatic long chain fatty acid metabolism and triglyceride accumulation contribute to insulin resistance in non-human primates by Kamath, Subhash, Chavez, Alberto O, Gastaldelli, Amalia, Casiraghi, Francesca, Halff, Glenn A, Abrahamian, Gregory A, Davalli, Alberto M, Bastarrachea, Raul A, Comuzzie, Anthony G, Guardado-Mendoza, Rodolfo, Jimenez-Ceja, Lilia M, Mattern, Vicki, Paez, Ana Maria, Ricotti, Andrea, Tejero, Mary E, Higgins, Paul B, Rodriguez-Sanchez, Iram Pablo, Tripathy, Devjit, DeFronzo, Ralph A, Dick, Jr, Edward J, Cline, Gary W, Folli, Franco

“…Non-alcoholic fatty liver disease (NAFLD) is characterized by accumulation of triglycerides (TG) in hepatocytes, which may also trigger cirrhosis. The…”
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Long-lasting remission of type 1 diabetes following treatment with topiramate for generalized seizures by Davalli, Alberto M., Perego, Carla, Folli, Franco B., Bosi, Emanuele

“…We report a case of unusually long-lasting remission of type 1 diabetes (T1D). The patient, a Caucasian man, at the age of 43 years developed a ketotic…”
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Effects of carboxypeptidase E overexpression on insulin mRNA levels, regulated insulin secretion, and proinsulin processing of pituitary GH3 cells transfected with a furin-cleavable human proinsulin cDNA by Polastri, Luca, Galbiati, Francesca, Folli, Franco, Davalli, Alberto M

“…We recently developed two rat pituitary GH3 cell clones engineered to secrete human insulin (InsGH3). InsGH3 cells convert proinsulin into mature insulin,…”
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Islet transplantation under the kidney capsule corrects the defects in glycogen metabolism in both liver and muscle of streptozocin-diabetic rats by Matarazzo, Margherita, Giardina, Maria Grazia, Guardasole, Vincenzo, Davalli, Alberto M, Horton, Edward S, Weir, Gordon C, Saccà, Luigi, Napoli, Raffaele

“…Insulin-deficient rats are characterized by multiple defects in the pathway of glycogen synthesis and breakdown in both liver and skeletal muscle. The aim of…”
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Paraneoplastic Insulin Resistance Syndrome in Advanced Aggressive Fibromatosis (Desmoid Tumor) Treated by Imatinib Mesylate by Folli, Franco, Galimberti, Gabriella, Pastore, Matteo, Davalli, Alberto M, Bosi, Emanuele

“…Laboratory investigations were normal, apart from features of nonketotic insulin-resistant diabetes with HbA^sub 1c^ 14.2%, 24-h blood glucose 300-500 mg/dl,…”
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