Search Results - "DASEN, J. S"

Signaling and transcriptional mechanisms in pituitary development by DASEN, Jeremy S, ROSENFELD, Michael G

“…During the development of the pituitary gland, distinct hormone-producing cell types arise from a common population of ectodermal progenitors, providing an…”
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Mutations in PROP1 cause familial combined pituitary hormone deficiency by WEI WU, COGAN, J. D, PHILLIPS, J. A, ROSENFELD, M. G, PFÄFFLE, R. W, DASEN, J. S, FRISCH, H, O'CONNELL, S. M, FLYNN, S. E, BROWN, M. R, MULLIS, P. E, PARKS, J. S

“…Combined pituitary hormone deficiency (CPHD) in man denotes impaired production of growth hormone (GH) and one or more of the other five anterior pituitary…”
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Pituitary lineage determination by the Prophet of Pit-1 homeodomain factor defective in Ames dwarfism by Sornson, Mark W, Wu, Wei, Dasen, Jeremy S, Flynn, Sarah E, Norman, Deborah J, O'Connell, Shawn M, Gukovsky, Ilya, Carrière, Catherine, Ryan, Aimee K, Miller, Andrew P, Zuo, Lin, Gleiberman, Anatoli S, Andersen, Bogi, Beamer, Wes G, Rosenfeld, Michael G

“…The gene apparently responsible for a heritable form of murine pituitary-dependent dwarfism (Ames dwarf, df) has been positionally cloned, identifying a novel,…”
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Signal-specific co-activator domain requirements for Pit-1 activation by Rosenfeld, Michael G, Xu, Lan, Lavinsky, Robert M, Dasen, Jeremy S, Flynn, Sarah E, McInerney, Eileen M, Mullen, Tina-Marie, Heinzel, Thorsten, Szeto, Daniel, Korzus, Edward, Kurokawa, Riki, Aggarwal, Aneel K, Rose, David W, Glass, Christopher K

“…POU-domain proteins, such as the pituitary-specific factor Pit-1, are members of the homeodomain family of proteins which are important in development and…”
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Motor neuron columnar fate imposed by sequential phases of Hox-c activity by Dasen, Jeremy S, Jessell, Thomas M, Liu, Jeh-Ping

“…The organization of neurons into columns is a prominent feature of central nervous system structure and function. In many regions of the central nervous system…”
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Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis by Dasen, J S, Martinez Barbera, J P, Herman, T S, Connell, S O, Olson, L, Ju, B, Tollkuhn, J, Baek, S H, Rose, D W, Rosenfeld, M G

“…Understanding the functional significance of the coordinate expression of specific corepressors and DNA-binding transcription factors remains a critical…”
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Reciprocal Interactions of Pit1 and GATA2 Mediate Signaling Gradient–Induced Determination of Pituitary Cell Types by Dasen, Jeremy S, O’Connell, Shawn M, Flynn, Sarah E, Treier, Mathias, Gleiberman, Anatoli S, Szeto, Daniel P, Hooshmand, Farideh, Aggarwal, Aneel K, Rosenfeld, Michael G

“…The mechanisms by which transient gradients of signaling molecules lead to emergence of specific cell types remain a central question in mammalian…”
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Combinatorial codes in signaling and synergy: lessons from pituitary development by Dasen, Jeremy S, Rosenfeld, Michael G

“…The development of the hormone-secreting cell types in the pituitary gland provides an excellent model system in which to explore the complex transcriptional…”
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Signaling mechanisms in pituitary morphogenesis and cell fate determination by Dasen, Jeremy S, Rosenfeld, Michael G

“…The development of the pituitary gland has provided an instructive model system for exploring the mechanisms by which differentiated cell types arise from a…”
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Factor-Specific Modulation of CREB-Binding Protein Acetyltransferase Activity by Perissi, Valentina, Dasen, Jeremy S., Kurokawa, Riki, Wang, Zhiyong, Korzus, Edward, Rose, David W., Glass, Christopher K., Rosenfeld, Michael G.

“…CREB-binding proteins (CBP) and p300 are essential transcriptional coactivators for a large number of regulated DNA-binding transcription factors, including…”
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Hox Repertoires for Motor Neuron Diversity and Connectivity Gated by a Single Accessory Factor, FoxP1 by Dasen, Jeremy S., De Camilli, Alessandro, Wang, Bin, Tucker, Philip W., Jessell, Thomas M.

“…The precision with which motor neurons innervate target muscles depends on a regulatory network of Hox transcription factors that translates neuronal identity…”
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Phylogenetic Footprinting of the Human Cytochrome c Oxidase Subunit Vb Promoter by Bachman, Nancy J., Yang, Tony L., Dasen, Jeremy S., Ernst, Robin E., Lomax, Margaret I.

“…The humanCOX5Bgene encodes subunit Vb of cytochromecoxidase (COX). COX Vb is 1 of the 10 subunits of the mitochondrial COX complex encoded by a nuclear gene…”
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A Hox Regulatory Network Establishes Motor Neuron Pool Identity and Target-Muscle Connectivity by Dasen, Jeremy S., Tice, Bonnie C., Brenner-Morton, Susan, Jessell, Thomas M.

“…Spinal motor neurons acquire specialized “pool” identities that determine their ability to form selective connections with target muscles in the limb, but the…”
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Paired-like repression/activation in pituitary development by Olson, Lorin E, Dasen, Jeremy S, Ju, Bong Gun, Tollkuhn, Jessica, Rosenfeld, Michael G

“…Pituitary gland development is controlled by signals that guide expression of specific combinations of transcription factors that dictate serial determination…”
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