Search Results - "DAS SARMA, Jayasri"

Connexin 43/47 channels are important for astrocyte/oligodendrocyte cross-talk in myelination and demyelination by Basu, Rahul, Das Sarma, Jayasri

“…The gap junctions (GJs), which form intercellular communicating channels between two apposing cells or form hemichannel with extracellular environment, perform…”
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CD40L protects against mouse hepatitis virus-induced neuroinflammatory demyelination by Saadi, Fareeha, Chakravarty, Debanjana, Kumar, Saurav, Kamble, Mithila, Saha, Bhaskar, Shindler, Kenneth S, Das Sarma, Jayasri

“…Neurotropic mouse hepatitis virus (MHV-A59/RSA59) infection in mice induces acute neuroinflammation due to direct neural cell dystrophy, which proceeds with…”
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Cytoplasmic tail of coronavirus spike protein has intracellular targeting signals by Sadasivan, Jibin, Singh, Manmeet, Sarma, Jayasri Das

“…Intracellular trafficking and localization studies of spike protein from SARS and OC43 showed that SARS spike protein is localized in the ER or ERGIC…”
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Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection by Das Sarma, Jayasri, Burrows, Amy, Rayman, Patricia, Hwang, Mi-Hyun, Kundu, Soumya, Sharma, Nikhil, Bergmann, Cornelia, Sen, Ganes C

“…The interferon-induced tetratricopeptide repeat protein (Ifit2) protects mice from lethal neurotropic viruses. Neurotropic coronavirus MHV-RSA59 infection of…”
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Effect of Microtubule Disruption on Neuronal Spread and Replication of Demyelinating and Nondemyelinating Strains of Mouse Hepatitis Virus In Vitro by Biswas, Kaushiki, Das Sarma, Jayasri

“…Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Suppressive Effect of IL-27 on Encephalitogenic Th17 Cells and the Effector Phase of Experimental Autoimmune Encephalomyelitis by Fitzgerald, Denise C, Ciric, Bogoljub, Touil, Tarik, Harle, Heather, Grammatikopolou, Julia, Sarma, Jayasri Das, Gran, Bruno, Zhang, Guang-Xian, Rostami, Abdolmohamad

“…IL-27 has been shown to play a suppressive role in experimental autoimmune encephalomyelitis (EAE) as demonstrated by more severe disease in IL-27R-deficient…”
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Isolation and Enrichment of Major Primary Neuroglial Cells from Neonatal Mouse Brain by Samal, Santosh Kumar, Sharma, Madhav, Sarma, Jayasri Das

“…The central nervous system (CNS) relies on the complex interaction of neuroglial cells to carry out vital physiological functions. To comprehensively…”
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Efficient approach to prepare multiple chemotherapeutic agent conjugated nanocarrier by N, Vijayakameswara Rao, Dinda, Himadri, Ganivada, Mutyala Naidu, Das Sarma, Jayasri, Shunmugam, Raja

“…A pH-responsive, multiple chemotherapeutic agent derived nanocarrier has been synthesized by conjugating doxorubicin, indomethacin, and folate to the backbone…”
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Two Consecutive Prolines in the Fusion Peptide of Murine β-Coronavirus Spike Protein Predominantly Determine Fusogenicity and May Be Essential but Not Sufficient to Cause Demyelination by Safiriyu, Abass Alao, Singh, Manmeet, Kishore, Abhinoy, Mulchandani, Vaishali, Maity, Dibyajyoti, Behera, Amrutamaya, Sinha, Bidisha, Pal, Debnath, Das Sarma, Jayasri

“…Combined in silico, in vitro, and in vivo comparative studies between isogenic-recombinant Mouse-Hepatitis-Virus-RSA59 and its proline deletion mutant,…”
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Connexin 43 mediated collective cell migration is independent of Golgi orientation by Sharma, Madhav, Mukherjee, Suvam, Shaw, Archana Kumari, Mondal, Anushka, Behera, Amrutamaya, Das, Jibitesh, Bose, Abhishek, Sinha, Bidisha, Sarma, Jayasri Das

“…Cell migration is vital for multiple physiological functions and is involved in the metastatic dissemination of tumour cells in various cancers. For effective…”
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Functional interleukin-17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitis by Das Sarma, Jayasri, Ciric, Bogoljub, Marek, Ryan, Sadhukhan, Sanjoy, Caruso, Michael L, Shafagh, Jasmine, Fitzgerald, Denise C, Shindler, Kenneth S, Rostami, Am

“…Interleukin-17A (IL-17A) is the founding member of a novel family of inflammatory cytokines that plays a critical role in the pathogenesis of many autoimmune…”
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Mouse hepatitis virus infection upregulates genes involved in innate immune responses by Chatterjee, Dhriti, Addya, Sankar, Khan, Reas S, Kenyon, Lawrence C, Choe, Alexander, Cohrs, Randall J, Shindler, Kenneth S, Sarma, Jayasri Das

“…Neurotropic recombinant strain of Mouse Hepatitis Virus, RSA59, induces meningo-encephalitis, myelitis and demyelination following intracranial inoculation…”
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Experimental Optic Neuritis Induced by a Demyelinating Strain of Mouse Hepatitis Virus by SHINDLER, Kenneth S, KENYON, Lawrence C, DUTT, Mahasweta, HINGLEY, Susan T, DAS SARMA, Jayasri

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Mechanism of Virus-Induced Demyelination by Das Sarma, Jayasri

“…Myelin forms an insulating sheath surrounding axons in the central and peripheral nervous systems and is essential for rapid propagation of neuronal action…”
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Magnetic cell sorting: A fast and effective method of concurrent isolation of high purity viable astrocytes and microglia from neonatal mouse brain tissue by Marek, Ryan, Caruso, Michael, Rostami, Abdolmohamad, Grinspan, Judith. B., Sarma, Jayasri Das

“…Pathologically altered functions of astrocytes and microglia play a pivotal role in diseases of the central nervous system (CNS). The complexity of the CNS…”
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ERp29 restricts Connexin43 oligomerization in the endoplasmic reticulum by Das, Shamie, Smith, Tekla D, Sarma, Jayasri Das, Ritzenthaler, Jeffrey D, Maza, Jose, Kaplan, Benjamin E, Cunningham, Leslie A, Suaud, Laurence, Hubbard, Michael J, Rubenstein, Ronald C, Koval, Michael

“…Connexin43 (Cx43) is a gap junction protein that forms multimeric channels that enable intercellular communication through the direct transfer of signals and…”
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The CD40/CD40 ligand dyad and its downstream effector molecule ISG54 in relating acute neuroinflammation with persistent, progressive demyelination by Hazra, Bishal, Das Sarma, Jayasri

“…Although Multiple Sclerosis (MS) is primarily thought to be an autoimmune condition, its possible viral etiology must be taken into consideration. When mice…”
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Microglia-mediated neuroinflammation is an amplifier of virus-induced neuropathology by Das Sarma, Jayasri

“…Microglia, the major resident immune cells in the central nervous system (CNS) are considered as the key cellular mediators of neuroinflammatory processes. In…”
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Microglia Play a Major Role in Direct Viral-Induced Demyelination by Ramachandra, S. G., Nag, Soma, Biswas, Kaushiki, Chatterjee, Dhriti, Das Sarma, Jayasri

“…Microglia are the resident macrophage-like populations in the central nervous system (CNS). Microglia remain quiescent, unable to perform effector and antigen…”
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Astrocytes as antigen‐presenting cells: expression of IL‐12/IL‐23 by Constantinescu, Cris S., Tani, Marie, Ransohoff, Richard M., Wysocka, Maria, Hilliard, Brendan, Fujioka, Toshiki, Murphy, Sean, Tighe, Patrick J., Sarma, Jayasri Das, Trinchieri, Giorgio, Rostami, Abdolmohamad

“…Interleukin‐12 (IL‐12, p70) a heterodimeric cytokine of p40 and p35 subunits, important for Th1‐type immune responses, has been attributed a prominent role in…”
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