Search Results - "DAS GUPTA, Tapas K"

A peptide fragment of azurin induces a p53-mediated cell cycle arrest in human breast cancer cells by Yamada, Tohru, Mehta, Rajeshwari R, Lekmine, Fatima, Christov, Konstantin, King, Marissa L, Majumdar, Dibyen, Shilkaitis, Anne, Green, Albert, Bratescu, Laura, Beattie, Craig W, Das Gupta, Tapas K

“…We report that amino acids 50 to 77 of azurin (p28) preferentially enter the human breast cancer cell lines MCF-7, ZR-75-1, and T47D through a…”
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MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells by Turner, Andrea, Li, Liang-Cheng, Pilli, Tania, Qian, Lixia, Wiley, Elizabeth Louise, Setty, Suman, Christov, Konstantin, Ganesh, Lakshmy, Maker, Ajay V, Li, Peifeng, Kanteti, Prasad, Das Gupta, Tapas K, Prabhakar, Bellur S

“…The Map kinase Activating Death Domain containing protein (MADD) isoform of the IG20 gene is over-expressed in different types of cancer tissues and cell lines…”
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Internalization of bacterial redox protein azurin in mammalian cells: entry domain and specificity by Yamada, Tohru, Fialho, Arsenio M., Punj, Vasu, Bratescu, Laura, Gupta, Tapas K. Das, Chakrabarty, Ananda M.

“…Summary Azurin is a member of a group of copper‐containing redox proteins called cupredoxins. Different cupredoxins are produced by different aerobic bacteria…”
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A Method of Tumor In Vivo Imaging with a New Peptide-Based Fluorescent Probe by Naffouje, Samer, Goto, Masahide, Ryoo, Ingeun, Green, Albert, Das Gupta, Tapas K, Yamada, Tohru

“…Precise surgical resection directly influences the prognosis and survival of patients with solid tumors. However, it is often difficult to distinguish tumor…”
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Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer by PUNJ, Vasu, BHATTACHARYYA, Suchita, LI, Gang, MAJUMDAR, Dibyen, CHAKRABARTY, Ananda M, GUPTA, Tapas K, SAINT-DIC, Djenann, VASU, Chenthamarakshan, CUNNINGHAM, Elizabeth A, GRAVES, Jewell, YAMADA, Tohru, CONSTANTINOU, Andreas I, CHRISTOV, Konstantin, WHITE, Bethany

“…Azurin, a copper-containing redox protein released by the pathogenic bacterium Pseudomonas aeruginosa, is highly cytotoxic to the human breast cancer cell line…”
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Tumor-targeting cell-penetrating peptide, p28, for glioblastoma imaging and therapy by Mander, Sunam, Naffouje, Samer A., Gao, Jin, Li, Weiguo, Christov, Konstantin, Green, Albert, Bongarzone, Ernesto R., Das Gupta, Tapas K., Yamada, Tohru

“…Despite recent advances in cancer research, glioblastoma multiforme (GBM) remains a highly aggressive brain tumor as its treatment options are limited. The…”
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Noncationic Peptides Obtained From Azurin Preferentially Enter Cancer Cells by TAYLOR, Brad N, MEHTA, Rajeshwari R, DAS GUPTA, Tapas K, YAMADA, Tohru, LEKMINE, Fatima, CHRISTOV, Konstantin, CHAKRABARTY, Ananda M, GREEN, Albert, BRATESCU, Laura, SHILKAITIS, Anne, BEATTIE, Craig W

“…Azurin, a member of the cupredoxin family of copper containing redox proteins, preferentially penetrates human cancer cells and exerts cytostatic and cytotoxic…”
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Image-guided surgery with a new tumour-targeting probe improves the identification of positive margins by Goto, Masahide, Ryoo, Ingeun, Naffouje, Samer, Mander, Sunam, Christov, Konstantin, Wang, Jing, Green, Albert, Shilkaitis, Anne, Das Gupta, Tapas K., Yamada, Tohru

“…Given the lack of visual discrepancy between malignant and surrounding normal tissue, current breast conserving surgery (BCS) is associated with a high…”
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Azurin, Plasmodium falciparum Malaria and HIV/AIDS: Inhibition of Parasitic and Viral Growth by Azurin by Chaudhari, Anita, Fialho, Arsenio M., Ratner, Deena, Gupta, Phalguni, Hong, Chang Soo, Kahali, Soumen, Yamada, Tohru, Haldar, Kasturi, Cho, Wonhwa, Chauhan, Virander S., Gupta, Tapas K. Das, Chakrabarty, Ananda M.

“…Azurin, a member of a family of copper-containing proteins involved in electron transfer called cupredoxins, demonstrates structural features similar to the…”
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Cross-talk between cancer and Pseudomonas aeruginosa mediates tumor suppression by Choi, Juliana K., Naffouje, Samer A., Goto, Masahide, Wang, Jing, Christov, Konstantin, Rademacher, David J., Green, Albert, Stecenko, Arlene A., Chakrabarty, Ananda M., Das Gupta, Tapas K., Yamada, Tohru

“…Microorganisms living at many sites in the human body compose a complex and dynamic community. Accumulating evidence suggests a significant role for…”
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p28-Mediated Activation of p53 in G2-M Phase of the Cell Cycle Enhances the Efficacy of DNA Damaging and Antimitotic Chemotherapy by Yamada, Tohru, Das Gupta, Tapas K, Beattie, Craig W

“…p28 is an anionic cell-penetrating peptide of 28 amino acids that activates wild-type and mutated p53, leading subsequently to selective inhibition of CDK2 and…”
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Randomized Trial of an Allogeneic Melanoma Lysate Vaccine With Low-Dose Interferon Alfa-2b Compared With High-Dose Interferon Alfa-2b for Resected Stage III Cutaneous Melanoma by MITCHELL, Malcolm S, ABRAMS, Judith, JAKOWATZ, James G, DAS GUPTA, Tapas K, RICHARDS, Jon M, SAMLOWSKI, Wolfram E, COSTANZI, John J, ARONSON, Frederick R, DEISSEROTH, Albert B, DUDEK, Arkadiusz Z, JONES, Vicky E, THOMPSON, John A, KASHANI-SABET, Mohammed, DECONTI, Ronald C, HWU, Wen-Jen, ATKINS, Michael B, WHITMAN, Eric, ERNSTOFF, Marc S, HALUSKA, Frank G

“…To compare the overall survival (OS) of patients with resected stage III melanoma administered active specific immunotherapy and low-dose interferon alfa-2b…”
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Cupredoxin−Cancer Interrelationship:  Azurin Binding with EphB2, Interference in EphB2 Tyrosine Phosphorylation, and Inhibition of Cancer Growth by Chaudhari, Anita, Mahfouz, Magdy, Fialho, Arsenio M, Yamada, Tohru, Granja, Ana Teresa, Zhu, Yonghua, Hashimoto, Wataru, Schlarb-Ridley, Beatrix, Cho, Wonhwa, Gupta, Tapas K. Das, Chakrabarty, Ananda M

“…Azurin is a member of a family of metalloproteins called cupredoxins. Although previously thought to be involved in electron transfer, azurin has recently been…”
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Bacterial Redox Protein Azurin, Tumor Suppressor Protein p53, and Regression of Cancer by Yamada, Tohru, Goto, Masatoshi, Punj, Vasu, Zaborina, Olga, Chen, Mei Ling, Kimbara, Kazuhide, Majumdar, Dibyen, Cunningham, Elizabeth, Tapas K. Das Gupta, Chakrabarty, Ananda M.

“…The use of live bacteria in the treatment of cancer has a long and interesting history. We report the use of a purified bacterial redox protein, azurin, that…”
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Apoptosis or Growth Arrest: Modulation of Tumor Suppressor p53's Specificity by Bacterial Redox Protein Azurin by Yamada, Tohru, Hiraoka, Yoshinori, Ikehata, Masateru, Kimbara, Kazuhide, Avner, Benjamin S., Tapas K. Das Gupta, Chakrabarty, Ananda M., Demain, Arnold L.

“…The tumor suppressor protein p53 is known to induce either apoptosis or growth arrest depending on cellular background. We have previously reported that a…”
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Beyond host–pathogen interactions: microbial defense strategy in the host environment by Fialho, Arsenio M, Stevens, Fred J, Das Gupta, Tapas K, Chakrabarty, Ananda M

“…Many extracellular pathogenic bacteria colonize human or animal bodies through evasion of the host immune system, a process called host–pathogen interaction…”
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Nontoxic Tumor-Targeting Optical Agents for Intraoperative Breast Tumor Imaging by Naffouje, Samer A., Goto, Masahide, Coward, Lori U., Gorman, Gregory S., Christov, Konstantin, Wang, Jing, Green, Albert, Shilkaitis, Anne, Das Gupta, Tapas K., Yamada, Tohru

“…Precise identification of the tumor margins during breast-conserving surgery (BCS) remains a challenge given the lack of visual discrepancy between malignant…”
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p28, an Anionic Cell-Penetrating Peptide, Increases the Activity of Wild Type and Mutated p53 without Altering Its Conformation by Yamada, Tohru, Das Gupta, Tapas K, Beattie, Craig W

“…p28, a cell penetrating peptide, binds to the DNA binding domain (DBD) of p53, inducing a post-translational increase in intracellular levels of wild type and…”
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The brain-penetrant cell-cycle inhibitor p28 sensitizes brain metastases to DNA-damaging agents by Mander, Sunam, Gorman, Gregory S, Coward, Lori U, Christov, Konstantin, Green, Albert, Das Gupta, Tapas K, Yamada, Tohru

“…Abstract Background Brain metastases (BMs), the most common tumors of the central nervous system, are life-threatening with a dismal prognosis. The major…”
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Melanoma cells can tolerate high levels of transcriptionally active endogenous p53 but are sensitive to retrovirus-transduced p53 by KICHINA, Julia V, RAUTH, Sikha, DAS GUPTA, Tapas K, GUDKOV, Andrei V

“…Malignant melanomas are frequently characterized by elevated levels of wild-type p53, suggesting that p53 function could be suppressed by a mechanism different…”
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