Search Results - "DAROCHA, Wanderson D"

Unveiling the intracellular survival gene kit of trypanosomatid parasites by Bartholomeu, Daniella Castanheira, de Paiva, Rita Marcia Cardoso, Mendes, Tiago A O, DaRocha, Wanderson D, Teixeira, Santuza M R

“…Trypanosomatids are unicellular protozoans of medical and economical relevance since they are the etiologic agents of infectious diseases in humans as well as…”
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Trypanin Disruption Affects the Motility and Infectivity of the Protozoan Trypanosoma cruzi by Saenz-Garcia, Jose L, Borges, Beatriz S, Souza-Melo, Normanda, Machado, Luiz V, Miranda, Juliana S, Pacheco-Lugo, Lisandro Alfonso, Moretti, Nilmar S, Wheleer, Richard, Soares Medeiros, Lia C, DaRocha, Wanderson D

“…The flagellum of Trypanosomatids is an organelle that contributes to multiple functions, including motility, cell division, and host-pathogen interaction…”
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Trypanosoma cruzi as an effective cancer antigen delivery vector by Junqueira, Caroline, Santos, Luara I, Galvão-Filho, Bruno, Teixeira, Santuza M, Rodrigues, Flávia G, DaRocha, Wanderson D, Chiari, Egler, Jungbluth, Achim A, Ritter, Gerd, Gnjatic, Sacha, Old, Lloyd J, Gazzinelli, Ricardo T

“…One of the main challenges in cancer research is the development of vaccines that induce effective and long-lived protective immunity against tumors…”
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Tests of cytoplasmic RNA interference (RNAi) and construction of a tetracycline-inducible T7 promoter system in Trypanosoma cruzi by DaRocha, Wanderson D., Otsu, Keiko, Teixeira, Santuza M.R., Donelson, John E.

“…The technique of RNA interference (RNAi) is exceedingly useful for knocking down the expression of a specific mRNA in African trypanosomes and other organisms…”
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Trypanosomatid comparative genomics: Contributions to the study of parasite biology and different parasitic diseases by Teixeira, Santuza M, de Paiva, Rita Márcia Cardoso, Kangussu-Marcolino, Monica M, Darocha, Wanderson D

“…In 2005, draft sequences of the genomes of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major, also known as the Tri-Tryp genomes, were published…”
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Identification of secreted virulence factors of Chromobacterium violaceum by Castro-Gomes, Thiago, Cardoso, Mariana S, DaRocha, Wanderson D, Laibida, Letícia A, Nascimento, Andréa M. A, Zuccherato, Luciana W, Horta, Maria Fátima, Bemquerer, Marcelo P, Teixeira, Santuza M. R

“…Chromobacterium violaceum, a component of tropical soil microbiota, is an opportunistic pathogenic bacterium that can infect humans and other animals. In…”
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Development of a dual reporter system to identify regulatory cis -acting elements in untranslated regions of Trypanosoma cruzi mRNAs by Araújo, Patrícia R, Burle-Caldas, Gabriela A, Silva-Pereira, Rosiane A, Bartholomeu, Daniella C, daRocha, Wanderson D, Teixeira, Santuza M.R

“…Abstract In trypanosomatids, transcription is polycistronic and gene expression control occurs mainly at the post-transcriptional level. To investigate the…”
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Correction: Antigenicity and Protective Efficacy of a Leishmania Amastigote-specific Protein, Member of the Super-oxygenase Family, against Visceral Leishmaniasis by Martins, Vivian T, Chávez-Fumagalli, Miguel A, Costa, Lourena E, Canavaci, Adriana M C, Lage, Paula S, Lage, Daniela P, Duarte, Mariana C, Valadares, Diogo G, Magalhães, Rubens D M, Ribeiro, Tatiana G, Nagem, Ronaldo A P, Darocha, Wanderson D, Régis, Wiliam C B, Soto, Manuel, Coelho, Eduardo A F, Fernandes, Ana Paula, Tavares, Carlos A P

“…[This corrects the article on p. e2148 in vol. 7.]…”
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CREditing: a tool for gene tuning in Trypanosoma cruzi by Pacheco-Lugo, Lisandro A., Sáenz-García, José L., Díaz-Olmos, Yirys, Netto-Costa, Rodrigo, Brant, Rodrigo S.C., DaRocha, Wanderson D.

“…[Display omitted] •Genetic manipulation is challenging in Trypanosoma cruzi, a difficult to manipulate parasite.•The delivery of CRE recombinase by…”
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Genomic organization and expression profile of the mucin-associated surface protein (masp) family of the human pathogen Trypanosoma cruzi by Bartholomeu, Daniella C, Cerqueira, Gustavo C, Leão, Ana Carolina A, daRocha, Wanderson D, Pais, Fabiano S, Macedo, Camila, Djikeng, Appolinaire, Teixeira, Santuza M.R, El-Sayed, Najib M

“…A novel large multigene family was recently identified in the human pathogen Trypanosoma cruzi, causative agent of Chagas disease, and corresponds to ~6% of…”
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Targeting epimastigotes of Trypanosoma cruzi with a peptide isolated from a phage display random library by Sáenz-Garcia, José L., Yamanaka, Isabel B., Pacheco-Lugo, Lisandro A., Miranda, Juliana S., Córneo, Emily S., Machado-de-Ávila, Ricardo A., De Moura, Juliana F., DaRocha, Wanderson D.

“…Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi, which is…”
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Zinc finger nuclease technology: A stable tool for high efficiency transformation in bloodstream form T. brucei by Schumann, Gabriela, Kangussu-Marcolino, Monica M., Doiron, Nicholas, Käser, Sandro, de Assis Burle-Caldas, Gabriela, DaRocha, Wanderson D., Teixeira, Santuza M., Roditi, Isabel

“…•Zinc finger nuclease system established in Trypanosoma brucei.•Cell lines that inducibly express zinc finger nucleases are stable.•Transfection efficiency…”
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Conditional removal of selectable markers in Trypanosoma cruzi using a site-specific recombination tool: Proof of concept by Kangussu-Marcolino, Monica M., Cunha, Ana Paula, Avila, Andrea R., Herman, Jean-Paul, DaRocha, Wanderson D.

“…•We have adapted the DiCRE system to remove selectable markers in Trypanosoma cruzi.•We constructed two vectors that can be transferred to different…”
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Genomic comparison of the endophyte Herbaspirillum seropedicae SmR1 and the phytopathogen Herbaspirillum rubrisubalbicans M1 by suppressive subtractive hybridization and partial genome sequencing by Monteiro, Rose A., Balsanelli, Eduardo, Tuleski, Thalita, Faoro, Helison, Cruz, Leonardo M., Wassem, Roseli, de Baura, Valter A., Tadra-Sfeir, Michelle Z., Weiss, Vinícius, DaRocha, Wanderson D., Muller-Santos, Marcelo, Chubatsu, Leda S., Huergo, Luciano F., Pedrosa, Fábio O., de Souza, Emanuel M.

“…Abstract Herbaspirillum rubrisubalbicans M1 causes the mottled stripe disease in sugarcane cv. B-4362. Inoculation of this cultivar with Herbaspirillum…”
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Analysis of expressed sequence tags from Trypanosoma cruzi amastigotes by Cerqueira, Gustavo C, DaRocha, Wanderson D, Campos, Priscila C, Zouain, Cláudia S, Teixeira, Santuza M R

“…A total of 880 expressed sequence tags (EST) originated from clones randomly selected from a Trypanosoma cruzi amastigote cDNA library have been analyzed. Of…”
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Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response by Campos, Priscila C., Silva, Viviane G., Furtado, Carolina, Machado-Silva, Alice, DaRocha, Wanderson D., Peloso, Eduardo F., Gadelha, Fernanda R., Medeiros, Marisa H.G., Lana, Gustavo de Carvalho, Chen, Ying, Barnes, Rebecca L., Passos-Silva, Danielle Gomes, McCulloch, Richard, Machado, Carlos Renato, Teixeira, Santuza M.R.

“…T. cruzi II strains accumulate more 8-oxoguanine in the kDNA after hydrogen peroxide-induced 18 oxidative stress than T. cruzi I strains. NT: untreated; T:…”
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Sequence diversity and evolution of multigene families in Trypanosoma cruzi by Cerqueira, Gustavo C., Bartholomeu, Daniella C., DaRocha, Wanderson D., Hou, Lihua, Freitas-Silva, Danielle M., Machado, Carlos Renato, El-Sayed, Najib M., Teixeira, Santuza M.R.

“…Several copies of genes belonging to three multigene families present in the genome of Trypanosoma cruzi were sequenced and comparatively analyzed across six…”
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Sequences involved in mRNA processing in Trypanosoma cruzi by Campos, Priscila C., Bartholomeu, Daniella C., DaRocha, Wanderson D., Cerqueira, Gustavo C., Teixeira, Santuza M.R.

“…Gene expression in Trypanosomatids requires processing of polycistronic transcripts to generate monocistronic mRNAs by cleavage events that are coupled to the…”
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Expression of exogenous genes in Trypanosoma cruzi: improving vectors and electroporation protocols by DAROCHA, Wanderson D, SILVA, Rosiane A, BARTHOLOMEU, Daniella C, PIRES, Simone F, FREITAS, Jorge M, MACEDO, Andrea M, VAZQUEZ, Martin P, LEVIN, Mariano J, TEIXEIRA, Santuza M. R

“…To improve transfection efficiency in Trypanosoma cruzi, we developed a new electroporation protocol and expression vectors which use luciferase and green and…”
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Molecular characterization of ribonucleoproteic antigens containing repeated amino acid sequences from Trypanosoma cruzi by Pais, Fabiano S., DaRocha, Wanderson D., Almeida, Ramon M., Leclercq, Sophie Y., Penido, Marcus L., Fragoso, Stenio P., Bartholomeu, Daniella C., Gazzinelli, Ricardo T., Teixeira, Santuza M.R.

“…Trypanosoma cruzi expresses several proteins containing antigenic amino acid repeats. Here we characterized TcRpL7a and TcRBP28, which carry similar repeat…”
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