Search Results - "DARNAUD, MARION"

Targeting gut flora to prevent progression of hepatocellular carcinoma by Darnaud, Marion, Faivre, Jamila, Moniaux, Nicolas

“…Increased translocation of intestinal bacteria is a hallmark of chronic liver disease and contributes to hepatic inflammation and fibrosis. Here we tested the…”
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A standardized gnotobiotic mouse model harboring a minimal 15-member mouse gut microbiota recapitulates SOPF/SPF phenotypes by Darnaud, Marion, De Vadder, Filipe, Bogeat, Pascaline, Boucinha, Lilia, Bulteau, Anne-Laure, Bunescu, Andrei, Couturier, Céline, Delgado, Ana, Dugua, Hélène, Elie, Céline, Mathieu, Alban, Novotná, Tereza, Ouattara, Djomangan Adama, Planel, Séverine, Saliou, Adrien, Šrůtková, Dagmar, Yansouni, Jennifer, Stecher, Bärbel, Schwarzer, Martin, Leulier, François, Tamellini, Andrea

“…Mus musculus is the classic mammalian model for biomedical research. Despite global efforts to standardize breeding and experimental procedures, the undefined…”
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Mass Spectrometry-Based Proteomics Reveal Alcohol Dehydrogenase 1B as a Blood Biomarker Candidate to Monitor Acetaminophen-Induced Liver Injury by Pailleux, Floriane, Maes, Pauline, Jaquinod, Michel, Barthelon, Justine, Darnaud, Marion, Lacoste, Claire, Vandenbrouck, Yves, Gilquin, Benoît, Louwagie, Mathilde, Hesse, Anne-Marie, Kraut, Alexandra, Garin, Jérôme, Leroy, Vincent, Zarski, Jean-Pierre, Bruley, Christophe, Couté, Yohann, Samuel, Didier, Ichai, Philippe, Faivre, Jamila, Brun, Virginie

“…Acute liver injury (ALI) is a severe disorder resulting from excessive hepatocyte cell death, and frequently caused by acetaminophen intoxication. Clinical…”
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The Reg3α (HIP/PAP) Lectin Suppresses Extracellular Oxidative Stress in a Murine Model of Acute Liver Failure by Moniaux, Nicolas, Darnaud, Marion, Garbin, Kévin, Dos Santos, Alexandre, Guettier, Catherine, Samuel, Didier, Amouyal, Gilles, Amouyal, Paul, Bréchot, Christian, Faivre, Jamila

“…Acute liver failure (ALF) is a rapidly progressive heterogeneous illness with high mortality rate and no widely accessible cure. A promising drug candidate…”
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Antimicrobial protein REG3A regulates glucose homeostasis and insulin resistance in obese diabetic mice by Gonzalez, Patrick, Dos Santos, Alexandre, Darnaud, Marion, Moniaux, Nicolas, Rapoud, Delphine, Lacoste, Claire, Nguyen, Tung-Son, Moullé, Valentine S., Deshayes, Alice, Amouyal, Gilles, Amouyal, Paul, Bréchot, Christian, Cruciani-Guglielmacci, Céline, Andréelli, Fabrizio, Magnan, Christophe, Faivre, Jamila

“…Innate immune mediators of pathogen clearance, including the secreted C-type lectins REG3 of the antimicrobial peptide (AMP) family, are known to be involved…”
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Human hepatocarcinoma‐intestine‐pancreas/pancreatitis‐associated protein cures fas‐induced acute liver failure in mice by attenuating free‐radical damage in injured livers by Moniaux, Nicolas, Song, Haiyan, Darnaud, Marion, Garbin, Kévin, Gigou, Michelle, Mitchell, Claudia, Samuel, Didier, Jamot, Laure, Amouyal, Paul, Amouyal, Gilles, Bréchot, Christian, Faivre, Jamila

“…Acute liver failure (ALF) is a rare syndrome with a difficult clinical management and a high mortality rate. During ALF, several molecular pathways governing…”
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Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis by Darnaud, Marion, Dos Santos, Alexandre, Gonzalez, Patrick, Augui, Sandrine, Lacoste, Claire, Desterke, Christophe, De Hertogh, Gert, Valentino, Emma, Braun, Emilie, Zheng, Jinzi, Boisgard, Raphael, Neut, Christel, Dubuquoy, Laurent, Chiappini, Franck, Samuel, Didier, Lepage, Patricia, Guerrieri, Francesca, Doré, Joel, Bréchot, Christian, Moniaux, Nicolas, Faivre, Jamila

“…Paneth cell dysfunction causes deficiencies in intestinal C-type lectins and antimicrobial peptides, which leads to dysbiosis of the intestinal microbiota,…”
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Development of Mass Spectrometry Imaging on skeletal muscle to characterize the local pro-inflammatory and pro-resolution lipid responses in a vaccination context by Ribette, Thomas, Charretier, Yannick, Laurent, Sebastien, Syntin, Patrick, Chautard, Emilie, Meniche, Xavier, Darnaud, Marion, Bequet, Frédéric, Beloeil, Laurent, Piras-Douce, Fabienne, Abi-Ghanem, Josephine

“…Vaccine reactogenicity is well documented at the clinical level but the mechanism involved at the local or systemic level are still poorly understood. Muscular…”
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Tumor suppressive role of the antimicrobial lectin REG3A targeting the O -GlcNAc glycosylation pathway by Moniaux, Nicolas, Geoffre, Nicolas, Deshayes, Alice, Dos Santos, Alexandre, Job, Sylvie, Lacoste, Claire, Nguyen, Tung-Son, Darnaud, Marion, Friedel-Arboleas, Mélanie, Guettier, Catherine, Purhonen, Janne, Kallijärvi, Jukka, Amouyal, Gilles, Amouyal, Paul, Bréchot, Christian, Vivès, Romain R, Buendia, Marie Annick, Issad, Tarik, Faivre, Jamila

“…Antimicrobial proteins of the regenerating family member 3 alpha (REG3A) family provide a first line of protection against infections and transformed cells…”
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1064-P: The Human Recombinant REG3A Protein ALF-5755 Restores Glucose Homeostasis and Insulin Sensitivity in High-Fat Fed Mice and in Ob/Ob Mice by DARNAUD, MARION, CRUCIANI-GUGLIELMACCI, CÉLINE, GONZALEZ, PATRICK, AMOUYAL, PAUL, AMOUYAL, GILLES, JAMOT, LAURE, MONIAUX, NICOLAS, ANDREELLI, FABRIZIO, BRÉCHOT, CHRISTIAN B., MAGNAN, CHRISTOPHE, FAIVRE, JAMILA

“…Introduction: REG3A (Regenerating islet-derived protein 3A) is a carbohydrate-binding protein belonging to the family of C-type lectins. REG3A has antioxidant…”
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Mass Spectrometry-Based Proteomics Reveal Alcohol Dehydrogenase 1B as a Blood Biomarker Candidate to Monitor Acetaminophen-Induced Liver Injury by Pailleux, Floriane, Maes, Pauline, Jaquinod, Michel, Barthelon, Justine, Darnaud, Marion, Lacoste, Claire, Vandenbrouck, Yves, Gilquin, Benoît, Louwagie, Mathilde, Hesse, Anne-Marie, Kraut, Alexandra, Garin, Jérôme, Leroy, Vincent, Zarski, Jean-Pierre, Bruley, Christophe, Couté, Yohann, Samuel, Didier, Ichai, Philippe, Faivre, Jamila, Brun, Virginie

“…Acute liver injury (ALI) is a severe disorder resulting from excessive hepatocyte cell death, and frequently caused by acetaminophen intoxication. Clinical…”
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Draft Genome Sequences of 15 Bacterial Species Constituting the Stable Defined Intestinal Microbiota of the GM15 Gnotobiotic Mouse Model by Elie, Céline, Mathieu, Alban, Saliou, Adrien, Villain, Adrien, Darnaud, Marion, Leulier, François, Tamellini, Andrea

“…The GM15 community is a bacterial consortium used to generate a novel standardized mouse model with a simplified controlled intestinal microbiota…”
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The Reg3[alpha] by Moniaux, Nicolas, Darnaud, Marion, Garbin, Kévin, Dos Santos, Alexandre, Guettier, Catherine, Samuel, Didier, Amouyal, Gilles, Amouyal, Paul, Bréchot, Christian, Faivre, Jamila

“…Background and Aims Acute liver failure (ALF) is a rapidly progressive heterogeneous illness with high mortality rate and no widely accessible cure. A…”
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The Reg3[alpha] Lectin Suppresses Extracellular Oxidative Stress in a Murine Model of Acute Liver Failure by Moniaux, Nicolas, Darnaud, Marion, Garbin, Kévin, Dos Santos, Alexandre, Guettier, Catherine, Samuel, Didier, Amouyal, Gilles, Amouyal, Paul, Bréchot, Christian, Faivre, Jamila

“…Background and Aims Acute liver failure (ALF) is a rapidly progressive heterogeneous illness with high mortality rate and no widely accessible cure. A…”
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HIP/PAP, a new drug for acute liver failure by Moniaux, Nicolas, Darnaud, Marion, Dos Santos, Alexandre, Jamot, Laure, Samuel, Didier, Amouyal, Paul, Amouyal, Gilles, Bréchot, Christian, Faivre, Jamila

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