Search Results - "DANOY, Patrick"

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1 by Burdon, Kathryn P, Macgregor, Stuart, Hewitt, Alex W, Sharma, Shiwani, Chidlow, Glyn, Mills, Richard A, Danoy, Patrick, Casson, Robert, Viswanathan, Ananth C, Liu, Jimmy Z, Landers, John, Henders, Anjali K, Wood, John, Souzeau, Emmanuelle, Crawford, April, Leo, Paul, Wang, Jie Jin, Rochtchina, Elena, Nyholt, Dale R, Martin, Nicholas G, Montgomery, Grant W, Mitchell, Paul, Brown, Matthew A, Mackey, David A, Craig, Jamie E

“…Jamie Craig and colleagues report a genome-wide association study for advanced open angle glaucoma (OAG). They identify variants near TMCO1 and in CDKN2B-AS1…”
Get full text

Association of variants at 1q32 and STAT3 with ankylosing spondylitis suggests genetic overlap with Crohn's disease by Danoy, Patrick, Pryce, Karena, Hadler, Johanna, Bradbury, Linda A, Farrar, Claire, Pointon, Jennifer, Ward, Michael, Weisman, Michael, Reveille, John D, Wordsworth, B Paul, Stone, Millicent A, Maksymowych, Walter P, Rahman, Proton, Gladman, Dafna, Inman, Robert D, Brown, Matthew A

“…Ankylosing spondylitis (AS) is a common inflammatory arthritic condition. Overt inflammatory bowel disease (IBD) occurs in about 10% of AS patients, and in…”
Get full text

A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways by Anderson, Robert P, Henry, Margaret J, Taylor, Roberta, Duncan, Emma L, Danoy, Patrick, Costa, Marylia J, Addison, Kathryn, Tye-Din, Jason A, Kotowicz, Mark A, Knight, Ross E, Pollock, Wendy, Nicholson, Geoffrey C, Toh, Ban-Hock, Brown, Matthew A, Pasco, Julie A

“…Changing perspectives on the natural history of celiac disease (CD), new serology and genetic tests, and amended histological criteria for diagnosis cast doubt…”
Get full text

Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese by Davidson, Stuart I, Liu, Yu, Danoy, Patrick A, Wu, Xin, Thomas, Gethin P, Jiang, Lei, Sun, Linyun, Wang, Niansong, Han, Jun, Han, Huanxing, Visscher, Peter M, Brown, Matthew A, Xu, Huji

“…Recent association studies by the Australo-Anglo-American Spondyloarthritis Consortium (TASC) in Caucasian European populations from Australia, North America…”
Get more information

Glaucoma Risk Alleles at CDKN2B-AS1 Are Associated with Lower Intraocular Pressure, Normal-Tension Glaucoma, and Advanced Glaucoma by Burdon, Kathryn P., PhD, Crawford, April, MBBS, Casson, Robert J., DPhil, FRANZCO, Hewitt, Alex W., MBBS, PhD, Landers, John, PhD, FRANZCO, Danoy, Patrick, PhD, Mackey, David A., PhD, FRANZCO, Mitchell, Paul, PhD, FRANZCO, Healey, Paul R., PhD, FRANZCO, Craig, Jamie E., DPhil, FRANZCO

“…Purpose Genetic variation at the 9p21 locus encompassing the CDKN2B-AS1 , CDKN2A , and CDKN2B genes has been associated with primary open-angle glaucoma (POAG)…”
Get full text

A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis by Field, Judith, Browning, Sharon R, Johnson, Laura J, Danoy, Patrick, Varney, Michael D, Tait, Brian D, Gandhi, Kaushal S, Charlesworth, Jac C, Heard, Robert N, Stewart, Graeme J, Kilpatrick, Trevor J, Foote, Simon J, Bahlo, Melanie, Butzkueven, Helmut, Wiley, James, Booth, David R, Taylor, Bruce V, Brown, Matthew A, Rubio, Justin P, Stankovich, Jim

“…We conducted an association study across the human leukocyte antigen (HLA) complex to identify loci associated with multiple sclerosis (MS). Comparing 1927…”
Get full text

Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients by Jensen, Cathy J, Stankovich, Jim, Van der Walt, Anneke, Bahlo, Melanie, Taylor, Bruce V, van der Mei, Ingrid A F, Foote, Simon J, Kilpatrick, Trevor J, Johnson, Laura J, Wilkins, Ella, Field, Judith, Danoy, Patrick, Brown, Matthew A, Rubio, Justin P, Butzkueven, Helmut

“…Recent association studies in multiple sclerosis (MS) have identified and replicated several single nucleotide polymorphism (SNP) susceptibility loci including…”
Get full text

A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk by Revez, J A, Bain, L, Chapman, B, Powell, J E, Jansen, R, Duffy, D L, Tung, J Y, Penninx, B W, Visscher, P M, De Geus, E J C, Boomsma, D I, Hinds, D A, Martin, N G, Montgomery, G W, Ferreira, M A R

“…The main genetic determinant of soluble interleukin 6 receptor (sIL-6R) levels is the missense variant rs2228145 that maps to the cleavage site of IL-6R. For…”
Get full text

Omission of Author Name in the Article by Davidson et al (Arthritis Rheum, July 2013) by Davidson, Stuart I., Jiang, Lei, Cortes, Adrian, Wu, Xin, Glazov, Evgeny A., Zheng, Yi, Danoy, Patrick A., Liu, Yi, Thomas, Gethin P., Brown, Matthew A., Xu, Huji

Get full text

Brief Report: High‐Throughput Sequencing of IL23R Reveals a Low‐Frequency, Nonsynonymous Single‐Nucleotide Polymorphism That Is Associated With Ankylosing Spondylitis in a Han Chinese Population by Davidson, Stuart I., Jiang, Lei, Cortes, Adrian, Wu, Xin, Glazov, Evgeny A., Zheng, Yi, Danoy, Patrick A., Liu, Yi, Thomas, Gethin P., Brown, Matthew A., Xu, Huji

“…Objective Ankylosing spondylitis (AS) is a highly heritable common inflammatory arthritis that targets the spine and sacroiliac joints of the pelvis, causing…”
Get full text

A naturally occurring genetic variant of human XRCC2 (R188H) confers increased resistance to cisplatin-induced DNA damage by Danoy, Patrick, Sonoda, Eiichiro, Lathrop, Mark, Takeda, Shunichi, Matsuda, Fumihiko

“…Homologous recombination, a major double strand break repair pathway, plays critical roles in maintaining genome stability. Genetic polymorphisms in HR genes…”
Get full text

Genetic influences on the end-stage effector phase of arthritis by Ji, H, Gauguier, D, Ohmura, K, Gonzalez, A, Duchatelle, V, Danoy, P, Garchon, H J, Degott, C, Lathrop, M, Benoist, C, Mathis, D

“…K/BxN T cell receptor transgenic mice are a model of inflammatory arthritis, most similar to rheumatoid arthritis, that is critically dependent on both T and B…”
Get full text

A High-Resolution Consensus Linkage Map of the Rat, Integrating Radiation Hybrid and Genetic Maps by Bihoreau, Marie-Thérèse, Sebag-Montefiore, Liam, Godfrey, Richard F., Wallis, Robert H., Brown, Joanna H., Danoy, Patrick A., Collins, Stephan C., Rouard, Mathias, Kaisaki, Pamela J., Lathrop, Mark, Gauguier, Dominique

“…We have constructed a high-resolution consensus genetic map of the rat in a single large intercross, which integrates 747 framework markers and 687 positions…”
Get full text

Genome-wide association study identifies five new schizophrenia loci by Ripke, Stephan, Sanders, Alan R, Kendler, Kenneth S, Levinson, Douglas F, Sklar, Pamela, Holmans, Peter A, Lin, Dan-Yu, Duan, Jubao, Ophoff, Roel A, Andreassen, Ole A, Scolnick, Edward, Cichon, Sven, St Clair, David, Corvin, Aiden, Gurling, Hugh, Werge, Thomas, Rujescu, Dan, Blackwood, Douglas H R, Pato, Carlos N, Malhotra, Anil K, Purcell, Shaun, Dudbridge, Frank, Neale, Benjamin M, Rossin, Lizzy, Visscher, Peter M, Posthuma, Danielle, Ruderfer, Douglas M, Fanous, Ayman, Stefansson, Hreinn, Steinberg, Stacy, Mowry, Bryan J, Golimbet, Vera, De Hert, Marc, Jonsson, Erik G, Bitter, Istvan, Pietilaeinen, Olli P H, Collier, David A, Tosato, Sarah, Agartz, Ingrid, Albus, Margot, Alexander, Madeline, Amdur, Richard L, Amin, Farooq, Bass, Nicholas, Bergen, Sarah E, Black, Donald W, Boerglum, Anders D, Brown, Matthew A, Bruggeman, Richard, Buccola, Nancy G

“…We examined the role of common genetic variation in schizophrenia in a genome-wide association study of substantial size: a stage 1 discovery sample of 21,856…”
Get full text

Association of ERAP1, but not IL23R, with ankylosing spondylitis in a Han Chinese population by Davidson, Stuart I., Wu, Xin, Liu, Yu, Wei, Meng, Danoy, Patrick A., Thomas, Gethin, Cai, Qing, Sun, Linyun, Duncan, Emma, Wang, Niansong, Yu, Qinghong, Xu, Anlong, Fu, Yonggui, Brown, Matthew A., Xu, Huji

“…Objective The results of a recent genome‐wide association study have shown that ERAP1 and IL23R are associated with ankylosing spondylitis (AS) in Caucasian…”
Get full text

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype by Ferreira, Manuel A.R., PhD, Matheson, Melanie C., PhD, Tang, Clara S., PhD, Granell, Raquel, PhD, Ang, Wei, PhD, Hui, Jennie, PhD, Kiefer, Amy K., PhD, Duffy, David L., PhD, Baltic, Svetlana, PhD, Danoy, Patrick, PhD, Bui, Minh, PhD, Price, Loren, PhD, Sly, Peter D., FRACP, Eriksson, Nicholas, PhD, Madden, Pamela A., PhD, Abramson, Michael J., PhD, Holt, Patrick G., FAA, Heath, Andrew C., DPhil, Hunter, Michael, PhD, Musk, Bill, FRACP, Robertson, Colin F., FRACP, Le Souëf, Peter, FRACP, Montgomery, Grant W., PhD, Henderson, A. John, MD, Tung, Joyce Y., PhD, Dharmage, Shyamali C., PhD, Brown, Matthew A., FRACP, James, Alan, FRACP, Thompson, Philip J., FRACP, Pennell, Craig, PhD, Martin, Nicholas G., PhD, Evans, David M., PhD, Hinds, David A., PhD, Hopper, John L., PhD

“…Background To date, no genome-wide association study (GWAS) has considered the combined phenotype of asthma with hay fever. Previous analyses of family data…”
Get full text

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk by Zheng, Hou-Feng, Tobias, Jon H, Duncan, Emma, Evans, David M, Eriksson, Joel, Paternoster, Lavinia, Yerges-Armstrong, Laura M, Lehtimäki, Terho, Bergström, Ulrica, Kähönen, Mika, Leo, Paul J, Raitakari, Olli, Laaksonen, Marika, Nicholson, Geoffrey C, Viikari, Jorma, Ladouceur, Martin, Lyytikäinen, Leo-Pekka, Medina-Gomez, Carolina, Rivadeneira, Fernando, Prince, Richard L, Sievanen, Harri, Leslie, William D, Mellström, Dan, Eisman, John A, Movérare-Skrtic, Sofia, Goltzman, David, Hanley, David A, Jones, Graeme, St Pourcain, Beate, Xiao, Yongjun, Timpson, Nicholas J, Smith, George Davey, Reid, Ian R, Ring, Susan M, Sambrook, Philip N, Karlsson, Magnus, Dennison, Elaine M, Kemp, John P, Danoy, Patrick, Sayers, Adrian, Wilson, Scott G, Nethander, Maria, McCloskey, Eugene, Vandenput, Liesbeth, Eastell, Richard, Liu, Jeff, Spector, Tim, Mitchell, Braxton D, Streeten, Elizabeth A, Brommage, Robert, Pettersson-Kymmer, Ulrika, Brown, Matthew A, Ohlsson, Claes, Richards, J Brent, Lorentzon, Mattias

“…We aimed to identify genetic variants associated with cortical bone thickness (CBT) and bone mineral density (BMD) by performing two separate genome-wide…”
Get full text

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20 by Bahlo, Melanie, Booth, David R, Broadley, Simon A, Brown, Matthew A, Foote, Simon J, Griffiths, Lyn R, Kilpatrick, Trevor J, Lechner-Scott, Jeanette, Moscato, Pablo, Perreau, Victoria M, Rubio, Justin P, Scott, Rodney J, Stankovich, Jim, Stewart, Graeme J, Taylor, Bruce V, Wiley, James, Clarke, Glynnis, Cox, Mathew B, Csurhes, Peter A, Danoy, Patrick, Drysdale, Karen, Field, Judith, Greer, Judith M, Guru, Preethi, Hadler, Johanna, McMorran, Brendan J, Jensen, Cathy J, Johnson, Laura J, McCallum, Ruth, Merriman, Marilyn, Merriman, Tony, Pryce, Karen, Tajouri, Lotfi, Wilkins, Ella J, Browning, Brian L, Browning, Sharon R, Perera, Devindri, Broadley, Simon, Butzkueven, Helmut, Carroll, William M, Chapman, Caron, Kermode, Allan G, Marriott, Mark, Mason, Deborah, Heard, Robert N, Pender, Michael P, Slee, Mark, Tubridy, Niall, Willoughby, Ernest

“…To identify multiple sclerosis (MS) susceptibility loci, we conducted a genome-wide association study (GWAS) in 1,618 cases and used shared data for 3,413…”
Get full text

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci by Reveille, John D, Sims, Anne-Marie, Danoy, Patrick, Evans, David M, Leo, Paul, Pointon, Jennifer J, Jin, Rui, Zhou, Xiaodong, Bradbury, Linda A, Appleton, Louise H, Davis, John C, Diekman, Laura, Doan, Tracey, Dowling, Alison, Duan, Ran, Duncan, Emma L, Farrar, Claire, Hadler, Johanna, Harvey, David, Karaderi, Tugce, Mogg, Rebecca, Pomeroy, Emma, Pryce, Karena, Taylor, Jacqueline, Savage, Laurie, Deloukas, Panos, Kumanduri, Vasudev, Peltonen, Leena, Ring, Sue M, Whittaker, Pamela, Glazov, Evgeny, Thomas, Gethin P, Maksymowych, Walter P, Inman, Robert D, Ward, Michael M, Stone, Millicent A, Weisman, Michael H, Wordsworth, B Paul, Brown, Matthew A

“…To identify susceptibility loci for ankylosing spondylitis, we undertook a genome-wide association study in 2,053 unrelated ankylosing spondylitis cases among…”
Get full text

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma by Ferreira, Manuel AR, Dr, Matheson, Melanie C, PhD, Duffy, David L, PhD, Marks, Guy B, Prof, Hui, Jennie, PhD, Le Souëf, Peter, Prof, Danoy, Patrick, PhD, Baltic, Svetlana, PhD, Nyholt, Dale R, PhD, Jenkins, Mark, PhD, Hayden, Catherine, PhD, Willemsen, Gonneke, PhD, Ang, Wei, MSc, Kuokkanen, Mikko, PhD, Beilby, John, PhD, Cheah, Faang, BSc, de Geus, Eco JC, PhD, Ramasamy, Adaikalavan, DPhil, Vedantam, Sailaja, PhD, Salomaa, Veikko, PhD, Madden, Pamela A, PhD, Heath, Andrew C, Prof, Hopper, John L, Prof, Visscher, Peter M, PhD, Musk, Bill, Prof, Leeder, Stephen R, Prof, Jarvelin, Marjo-Riitta, Prof, Pennell, Craig, PhD, Boomsma, Dorret I, Prof, Hirschhorn, Joel N, Prof, Walters, Haydn, Prof, Martin, Nicholas G, Prof, James, Alan, FRACP, Jones, Graham, PhD, Abramson, Michael J, Prof, Robertson, Colin F, FRACP, Dharmage, Shyamali C, PhD, Brown, Matthew A, Prof, Montgomery, Grant W, PhD, Thompson, Philip J, Prof

“…Summary Background We aimed to identify novel genetic variants affecting asthma risk, since these might provide novel insights into molecular mechanisms…”
Get full text