Search Results - "DANIS, V. A."

Cytokine production by normal human monocytes: inter‐subject variation and relationship to an IL‐1 receptor antagonist (IL‐1Ra) gene polymorphism by DANIS, V. A., MILLINGTON, M., HYLAND, V. J., GRENNAN, D.

“…SUMMARY Monocytes from different individuals show variable cytokine production in response to a variety of stimuli. We wished to determine the sets of…”
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Effect of gonadal steroids on the production of IL-1 and IL-6 by blood mononuclear cells in vitro by Li, Z G, Danis, V A, Brooks, P M

“…Sex hormones have profound effects on immune responses and may influence the outcome of autoimmune diseases such as rheumatoid arthritis (RA). We investigated…”
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In Vivo Production of Cytokines and β (C-C) Chemokines in Human Recurrent Herpes Simplex Lesions—Do Herpes Simplex Virus-Infected Keratinocytes Contribute to Their Production? by Miklos, Zorka, Danis, Vic A., Adams, Susan, Lloyd, Andrew R., Adrian, Deborah L., Cunningham, Anthony L.

“…Recurrent human herpes simplex lesions are infiltrated by macrophages and CD4 and CD8 lymphocytes, which secrete cytokines and chemokines. Vesicle fluid was…”
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Circulating cytokine levels in patients with rheumatoid arthritis: results of a double blind trial with sulphasalazine by Danis, V A, Franic, G M, Rathjen, D A, Laurent, R M, Brooks, P M

“…Interleukin 1 (IL-1), IL-6, and tumour necrosis factor (TNF) alpha are pleiotropic cytokines produced predominantly by macrophages which have been implicated…”
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Increased frequency of the uncommon allele of a tumour necrosis factor alpha gene polymorphism in rheumatoid arthritis and systemic lupus erythematosus by Danis, V A, Millington, M, Hyland, V, Lawford, R, Huang, Q, Grennan, D

“…The frequency of the uncommon allele (TNF2) of a polymorphism in the promoter region of the tumour necrosis factor alpha (TNF alpha) gene in patients with…”
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Effects of granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), IL‐2, interferon‐gamma (IFN‐γ), tumour necrosis factor‐alpha (TNF‐α) and IL‐6 on the production of immunoreactive IL‐1 and TNF‐α by human monocytes by DANIS, V. A., FRANIC, G. M., RATHJEN, D. A., BROOKS, P. M.

“…SUMMARY The effects of GM‐CSF, IL‐2, IFN‐γ, TNF‐α and IL‐6 on the production of IL‐1 (both secreted and cell associated) and TNF‐α by peripheral blood…”
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Interleukin-1 production and cell-activation response to cytomegalovirus infection of vascular endothelial cells by WOODROFFE, S. B, GARNETT, H. M, DANIS, V. A

“…Human cytomegalovirus (HCMV) is a source of major complications in immunosuppressed individuals, and endothelial involvement in HCMV infection is well…”
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Interleukin-1 secretion by peripheral blood monocytes and synovial macrophages from patients with rheumatoid arthritis by Danis, V A, March, L M, Nelson, D S, Brooks, P M

“…Blood monocytes and synovial fluid and tissue macrophages were examined for their ability to produce interleukin-1 (IL-1) measured in a mouse thymocyte…”
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The effect of gold sodium thiomalate and auranofin on lipopolysaccharide‐induced interleukin‐1 production by blood monocytes in vitro: variation in healthy subjects and patients with arthritis by DANIS, V. A., KULESZ, A. J., NELSON, D. S., BROOKS, P. M.

“…SUMMARY The anti‐rheumatic gold compounds gold sodium thiomalate (GST) and auranofin (AF) have variable and often unpredictable effects in patients treated for…”
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Lack of association between an interleukin-1 receptor antagonist gene polymorphism and systemic lupus erythematosus by Danis, V A, Millington, M, Huang, Q, Hyland, V, Grennan, D

“…Non-MHC linked genes may contribute to genetic predisposition to the development of systemic lupus erythematosus. The possibility that cytokine genes may be…”
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Influence of nutritional status on immune functions in patients with Crohn's disease by Harries, A D, Danis, V A, Heatley, R V

“…Nutritional status and immune function were correlated with clinical features in 56 patients with Crohn's disease. These were divided arbitrarily into either…”
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The effect of slow-acting anti-rheumatic drugs (SAARDs) and combinations of SAARDs on monokine production in vitro by Danis, V A, Franic, G M, Brooks, P M

“…The mode of action of slow-acting anti-rheumatic drugs (SAARDs) is complex but may often include effects on cytokine (interleukin-1, IL-1, and tumour necrosis…”
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Antigen-antibody complexes in inflammatory bowel disease by Danis, V A, Harries, A D, Heatley, R V

“…One hundred and sixty patients have been studied to assess the significance of circulating antigen-antibody complexes in inflammatory bowel disease (IBD). Sera…”
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Pokeweed mitogen stimulated immunoglobulin production by peripheral blood lymphocytes in vitro: evidence for disordered immunoregulation in patients with ulcerative colitis and Crohn's disease by DANIS, V. A, HEATLEY, R. V

“…Production of immunoglobulins (G, A, M) by pokeweed mitogen stimulated peripheral blood lymphocytes was studied in 81 patients with inflammatory bowel disease…”
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Bimodal effect of gold on IL-1 production by blood monocytes by Danis, V A, Kulesz, A, Nelson, D S, Brooks, P M

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In vitro immunoglobulin secretion by normal human gastrointestinal mucosal tissues, and alterations in patients with inflammatory bowel disease by DANIS, V. A, HARRIES, A. D, HEATLEY, R. V

“…Intestinal mucosal immunoglobulin secretion in vitro has been studied by culture of endoscopic biopsy tissues obtained from various sites along the…”
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Evidence for regulation of human colonic mucosal immunoglobulin secretion by intestinal lymphoid cells by Danis, V A, Heatley, R V

“…In vitro immunoglobulin secretion has been studied using isolated colonic mucosal lymphoid cell populations obtained from 41 patients with non-inflammatory…”
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In vitro IgE production by peripheral blood lymphocytes and rectal mucosal biopsies and antigen-induced basophil degranulation in patients with inflammatory bowel disease by Smart, C, Danis, V A, Heatley, R V

“…IgE production by peripheral blood lymphocytes (PBL) and rectal mucosal biopsies in vitro has been examined in patients with ulcerative colitis (UC) and…”
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Cytokine regulation of human monocyte interleukin‐1 (IL‐1) production in vitro. Enhancement of IL‐1 production by interferon (IFN) gamma, tumour necrosis factor‐alpha, IL‐2 and IL‐1, and inhibition by IFN‐alpha by DANIS, V. A., KULESZ, A. J., NELSON, D. S., BROOKS, P. M.

“…SUMMARY IL‐1 production (secreted and cell‐associated) was measured in monocyte cultures stimulated by a variety of agents in vitro. Monocytes either adherent…”
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The effect of gold treatment on monocyte interleukin-1 production in rheumatoid arthritis. A prospective study by Danis, V A, Kulesz, A J, Kelly, D E, Nelson, D S, Brooks, P M

“…Monocyte interleukin-1 (IL-1) production in vitro was studied in 49 patients with rheumatoid arthritis (RA) and 31 controls. Twenty-six of the RA patients were…”
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